Search of human proteins with 33469941

Search of human proteins with 33469941

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|33469941 RNA polymerase I polypeptide B isoform 1 [Homo
sapiens]
         (1135 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|33469941 RNA polymerase I polypeptide B isoform 1 [Homo sapiens]  2323   0.0  
gi|212286172 RNA polymerase I polypeptide B isoform 2 [Homo sapi...  2123   0.0  
gi|238908503 DNA-directed RNA polymerase III B isoform 1 [Homo s...   406   e-113
gi|238908505 DNA-directed RNA polymerase III B isoform 2 [Homo s...   402   e-112
gi|4505941 DNA directed RNA polymerase II polypeptide B [Homo sa...   383   e-106
gi|61742777 leucyl/cystinyl aminopeptidase isoform 1 [Homo sapiens]    36   0.24 
gi|61742775 leucyl/cystinyl aminopeptidase isoform 2 [Homo sapiens]    36   0.24 
gi|96975023 ankyrin repeat and death domain containing 1A [Homo ...    31   7.6  

>gi|33469941 RNA polymerase I polypeptide B isoform 1 [Homo sapiens]
          Length = 1135

 Score = 2323 bits (6021), Expect = 0.0
 Identities = 1135/1135 (100%), Positives = 1135/1135 (100%)

Query: 1    MDPGSRWRNLPSGPSLKHLTDPSYGIPREQQKAALQELTRAHVESFNYAVHEGLGLAVQA 60
            MDPGSRWRNLPSGPSLKHLTDPSYGIPREQQKAALQELTRAHVESFNYAVHEGLGLAVQA
Sbjct: 1    MDPGSRWRNLPSGPSLKHLTDPSYGIPREQQKAALQELTRAHVESFNYAVHEGLGLAVQA 60

Query: 61   IPPFEFAFKDERISFTILDAVISPPTVPKGTICKEANVYPAECRGRRSTYRGKLTADINW 120
            IPPFEFAFKDERISFTILDAVISPPTVPKGTICKEANVYPAECRGRRSTYRGKLTADINW
Sbjct: 61   IPPFEFAFKDERISFTILDAVISPPTVPKGTICKEANVYPAECRGRRSTYRGKLTADINW 120

Query: 121  AVNGISKGIIKQFLGYVPIMVKSKLCNLRNLPPQALIEHHEEAEEMGGYFIINGIEKVIR 180
            AVNGISKGIIKQFLGYVPIMVKSKLCNLRNLPPQALIEHHEEAEEMGGYFIINGIEKVIR
Sbjct: 121  AVNGISKGIIKQFLGYVPIMVKSKLCNLRNLPPQALIEHHEEAEEMGGYFIINGIEKVIR 180

Query: 181  MLIMPRRNFPIAMIRPKWKTRGPGYTQYGVSMHCVREEHSAVNMNLHYLENGTVMLNFIY 240
            MLIMPRRNFPIAMIRPKWKTRGPGYTQYGVSMHCVREEHSAVNMNLHYLENGTVMLNFIY
Sbjct: 181  MLIMPRRNFPIAMIRPKWKTRGPGYTQYGVSMHCVREEHSAVNMNLHYLENGTVMLNFIY 240

Query: 241  RKELFFLPLGFALKALVSFSDYQIFQELIKGKEDDSFLRNSVSQMLRIVMEEGCSTQKQV 300
            RKELFFLPLGFALKALVSFSDYQIFQELIKGKEDDSFLRNSVSQMLRIVMEEGCSTQKQV
Sbjct: 241  RKELFFLPLGFALKALVSFSDYQIFQELIKGKEDDSFLRNSVSQMLRIVMEEGCSTQKQV 300

Query: 301  LNYLGECFRVKLNVPDWYPNEQAAEFLFNQCICIHLKSNTEKFYMLCLMTRKLFALAKGE 360
            LNYLGECFRVKLNVPDWYPNEQAAEFLFNQCICIHLKSNTEKFYMLCLMTRKLFALAKGE
Sbjct: 301  LNYLGECFRVKLNVPDWYPNEQAAEFLFNQCICIHLKSNTEKFYMLCLMTRKLFALAKGE 360

Query: 361  CMEDNPDSLVNQEVLTPGQLFLMFLKEKLEGWLVSIKIAFDKKAQKTSVSMNTDNLMRIF 420
            CMEDNPDSLVNQEVLTPGQLFLMFLKEKLEGWLVSIKIAFDKKAQKTSVSMNTDNLMRIF
Sbjct: 361  CMEDNPDSLVNQEVLTPGQLFLMFLKEKLEGWLVSIKIAFDKKAQKTSVSMNTDNLMRIF 420

Query: 421  TMGIDLTKPFEYLFATGNLRSKTGLGLLQDSGLCVVADKLNFIRYLSHFRCVHRGADFAK 480
            TMGIDLTKPFEYLFATGNLRSKTGLGLLQDSGLCVVADKLNFIRYLSHFRCVHRGADFAK
Sbjct: 421  TMGIDLTKPFEYLFATGNLRSKTGLGLLQDSGLCVVADKLNFIRYLSHFRCVHRGADFAK 480

Query: 481  MRTTTVRRLLPESWGFLCPVHTPDGEPCGLMNHLTAVCEVVTQFVYTASIPALLCNLGVT 540
            MRTTTVRRLLPESWGFLCPVHTPDGEPCGLMNHLTAVCEVVTQFVYTASIPALLCNLGVT
Sbjct: 481  MRTTTVRRLLPESWGFLCPVHTPDGEPCGLMNHLTAVCEVVTQFVYTASIPALLCNLGVT 540

Query: 541  PIDGAPHRSYSECYPVLLDGVMVGWVDKDLAPGIADSLRHFKVLREKRIPPWMEVVLIPM 600
            PIDGAPHRSYSECYPVLLDGVMVGWVDKDLAPGIADSLRHFKVLREKRIPPWMEVVLIPM
Sbjct: 541  PIDGAPHRSYSECYPVLLDGVMVGWVDKDLAPGIADSLRHFKVLREKRIPPWMEVVLIPM 600

Query: 601  TGKPSLYPGLFLFTTPCRLVRPVQNLALGKEELIGTMEQIFMNVAIFEDEVFAGVTTHQE 660
            TGKPSLYPGLFLFTTPCRLVRPVQNLALGKEELIGTMEQIFMNVAIFEDEVFAGVTTHQE
Sbjct: 601  TGKPSLYPGLFLFTTPCRLVRPVQNLALGKEELIGTMEQIFMNVAIFEDEVFAGVTTHQE 660

Query: 661  LFPHSLLSVIANFIPFSDHNQSPRNMYQCQMGKQTMGFPLLTYQDRSDNKLYRLQTPQSP 720
            LFPHSLLSVIANFIPFSDHNQSPRNMYQCQMGKQTMGFPLLTYQDRSDNKLYRLQTPQSP
Sbjct: 661  LFPHSLLSVIANFIPFSDHNQSPRNMYQCQMGKQTMGFPLLTYQDRSDNKLYRLQTPQSP 720

Query: 721  LVRPSMYDYYDMDNYPIGTNAIVAVISYTGYDMEDAMIVNKASWERGFAHGSVYKSEFID 780
            LVRPSMYDYYDMDNYPIGTNAIVAVISYTGYDMEDAMIVNKASWERGFAHGSVYKSEFID
Sbjct: 721  LVRPSMYDYYDMDNYPIGTNAIVAVISYTGYDMEDAMIVNKASWERGFAHGSVYKSEFID 780

Query: 781  LSEKIKQGDSSLVFGIKPGDPRVLQKLDDDGLPFIGAKLQYGDPYYSYLNLNTGESFVMY 840
            LSEKIKQGDSSLVFGIKPGDPRVLQKLDDDGLPFIGAKLQYGDPYYSYLNLNTGESFVMY
Sbjct: 781  LSEKIKQGDSSLVFGIKPGDPRVLQKLDDDGLPFIGAKLQYGDPYYSYLNLNTGESFVMY 840

Query: 841  YKSKENCVVDNIKVCSNDTGSGKFKCVCITMRVPRNPTIGDKFASRHGQKGILSRLWPAE 900
            YKSKENCVVDNIKVCSNDTGSGKFKCVCITMRVPRNPTIGDKFASRHGQKGILSRLWPAE
Sbjct: 841  YKSKENCVVDNIKVCSNDTGSGKFKCVCITMRVPRNPTIGDKFASRHGQKGILSRLWPAE 900

Query: 901  DMPFTESGMVPDILFNPHGFPSRMTIGMLIESMAGKSAALHGLCHDATPFIFSEENSALE 960
            DMPFTESGMVPDILFNPHGFPSRMTIGMLIESMAGKSAALHGLCHDATPFIFSEENSALE
Sbjct: 901  DMPFTESGMVPDILFNPHGFPSRMTIGMLIESMAGKSAALHGLCHDATPFIFSEENSALE 960

Query: 961  YFGEMLKAAGYNFYGTERLYSGISGLELEADIFIGVVYYQRLRHMVSDKFQVRTTGARDR 1020
            YFGEMLKAAGYNFYGTERLYSGISGLELEADIFIGVVYYQRLRHMVSDKFQVRTTGARDR
Sbjct: 961  YFGEMLKAAGYNFYGTERLYSGISGLELEADIFIGVVYYQRLRHMVSDKFQVRTTGARDR 1020

Query: 1021 VTNQPIGGRNVQGGIRFGEMERDALLAHGTSFLLHDRLFNCSDRSVAHVCVKCGSLLSPL 1080
            VTNQPIGGRNVQGGIRFGEMERDALLAHGTSFLLHDRLFNCSDRSVAHVCVKCGSLLSPL
Sbjct: 1021 VTNQPIGGRNVQGGIRFGEMERDALLAHGTSFLLHDRLFNCSDRSVAHVCVKCGSLLSPL 1080

Query: 1081 LEKPPPSWSAMRNRKYNCTLCSRSDTIDTVSVPYVFRYFVAELAAMNIKVKLDVV 1135
            LEKPPPSWSAMRNRKYNCTLCSRSDTIDTVSVPYVFRYFVAELAAMNIKVKLDVV
Sbjct: 1081 LEKPPPSWSAMRNRKYNCTLCSRSDTIDTVSVPYVFRYFVAELAAMNIKVKLDVV 1135


>gi|212286172 RNA polymerase I polypeptide B isoform 2 [Homo sapiens]
          Length = 1079

 Score = 2123 bits (5502), Expect = 0.0
 Identities = 1054/1135 (92%), Positives = 1060/1135 (93%), Gaps = 56/1135 (4%)

Query: 1    MDPGSRWRNLPSGPSLKHLTDPSYGIPREQQKAALQELTRAHVESFNYAVHEGLGLAVQA 60
            MDPGSRWRNLPSGPSLKHLTDPSYGIP        +E  +A ++    A  E    AV  
Sbjct: 1    MDPGSRWRNLPSGPSLKHLTDPSYGIP--------REQQKAALQELTRAHVESFNYAVH- 51

Query: 61   IPPFEFAFKDERISFTILDAVISPPTVPKGTICKEANVYPAECRGRRSTYRGKLTADINW 120
                      E +   +                                      ADINW
Sbjct: 52   ----------EGLGLAV-------------------------------------QADINW 64

Query: 121  AVNGISKGIIKQFLGYVPIMVKSKLCNLRNLPPQALIEHHEEAEEMGGYFIINGIEKVIR 180
            AVNGISKGIIKQFLGYVPIMVKSKLCNLRNLPPQALIEHHEEAEEMGGYFIINGIEKVIR
Sbjct: 65   AVNGISKGIIKQFLGYVPIMVKSKLCNLRNLPPQALIEHHEEAEEMGGYFIINGIEKVIR 124

Query: 181  MLIMPRRNFPIAMIRPKWKTRGPGYTQYGVSMHCVREEHSAVNMNLHYLENGTVMLNFIY 240
            MLIMPRRNFPIAMIRPKWKTRGPGYTQYGVSMHCVREEHSAVNMNLHYLENGTVMLNFIY
Sbjct: 125  MLIMPRRNFPIAMIRPKWKTRGPGYTQYGVSMHCVREEHSAVNMNLHYLENGTVMLNFIY 184

Query: 241  RKELFFLPLGFALKALVSFSDYQIFQELIKGKEDDSFLRNSVSQMLRIVMEEGCSTQKQV 300
            RKELFFLPLGFALKALVSFSDYQIFQELIKGKEDDSFLRNSVSQMLRIVMEEGCSTQKQV
Sbjct: 185  RKELFFLPLGFALKALVSFSDYQIFQELIKGKEDDSFLRNSVSQMLRIVMEEGCSTQKQV 244

Query: 301  LNYLGECFRVKLNVPDWYPNEQAAEFLFNQCICIHLKSNTEKFYMLCLMTRKLFALAKGE 360
            LNYLGECFRVKLNVPDWYPNEQAAEFLFNQCICIHLKSNTEKFYMLCLMTRKLFALAKGE
Sbjct: 245  LNYLGECFRVKLNVPDWYPNEQAAEFLFNQCICIHLKSNTEKFYMLCLMTRKLFALAKGE 304

Query: 361  CMEDNPDSLVNQEVLTPGQLFLMFLKEKLEGWLVSIKIAFDKKAQKTSVSMNTDNLMRIF 420
            CMEDNPDSLVNQEVLTPGQLFLMFLKEKLEGWLVSIKIAFDKKAQKTSVSMNTDNLMRIF
Sbjct: 305  CMEDNPDSLVNQEVLTPGQLFLMFLKEKLEGWLVSIKIAFDKKAQKTSVSMNTDNLMRIF 364

Query: 421  TMGIDLTKPFEYLFATGNLRSKTGLGLLQDSGLCVVADKLNFIRYLSHFRCVHRGADFAK 480
            TMGIDLTKPFEYLFATGNLRSKTGLGLLQDSGLCVVADKLNFIRYLSHFRCVHRGADFAK
Sbjct: 365  TMGIDLTKPFEYLFATGNLRSKTGLGLLQDSGLCVVADKLNFIRYLSHFRCVHRGADFAK 424

Query: 481  MRTTTVRRLLPESWGFLCPVHTPDGEPCGLMNHLTAVCEVVTQFVYTASIPALLCNLGVT 540
            MRTTTVRRLLPESWGFLCPVHTPDGEPCGLMNHLTAVCEVVTQFVYTASIPALLCNLGVT
Sbjct: 425  MRTTTVRRLLPESWGFLCPVHTPDGEPCGLMNHLTAVCEVVTQFVYTASIPALLCNLGVT 484

Query: 541  PIDGAPHRSYSECYPVLLDGVMVGWVDKDLAPGIADSLRHFKVLREKRIPPWMEVVLIPM 600
            PIDGAPHRSYSECYPVLLDGVMVGWVDKDLAPGIADSLRHFKVLREKRIPPWMEVVLIPM
Sbjct: 485  PIDGAPHRSYSECYPVLLDGVMVGWVDKDLAPGIADSLRHFKVLREKRIPPWMEVVLIPM 544

Query: 601  TGKPSLYPGLFLFTTPCRLVRPVQNLALGKEELIGTMEQIFMNVAIFEDEVFAGVTTHQE 660
            TGKPSLYPGLFLFTTPCRLVRPVQNLALGKEELIGTMEQIFMNVAIFEDEVFAGVTTHQE
Sbjct: 545  TGKPSLYPGLFLFTTPCRLVRPVQNLALGKEELIGTMEQIFMNVAIFEDEVFAGVTTHQE 604

Query: 661  LFPHSLLSVIANFIPFSDHNQSPRNMYQCQMGKQTMGFPLLTYQDRSDNKLYRLQTPQSP 720
            LFPHSLLSVIANFIPFSDHNQSPRNMYQCQMGKQTMGFPLLTYQDRSDNKLYRLQTPQSP
Sbjct: 605  LFPHSLLSVIANFIPFSDHNQSPRNMYQCQMGKQTMGFPLLTYQDRSDNKLYRLQTPQSP 664

Query: 721  LVRPSMYDYYDMDNYPIGTNAIVAVISYTGYDMEDAMIVNKASWERGFAHGSVYKSEFID 780
            LVRPSMYDYYDMDNYPIGTNAIVAVISYTGYDMEDAMIVNKASWERGFAHGSVYKSEFID
Sbjct: 665  LVRPSMYDYYDMDNYPIGTNAIVAVISYTGYDMEDAMIVNKASWERGFAHGSVYKSEFID 724

Query: 781  LSEKIKQGDSSLVFGIKPGDPRVLQKLDDDGLPFIGAKLQYGDPYYSYLNLNTGESFVMY 840
            LSEKIKQGDSSLVFGIKPGDPRVLQKLDDDGLPFIGAKLQYGDPYYSYLNLNTGESFVMY
Sbjct: 725  LSEKIKQGDSSLVFGIKPGDPRVLQKLDDDGLPFIGAKLQYGDPYYSYLNLNTGESFVMY 784

Query: 841  YKSKENCVVDNIKVCSNDTGSGKFKCVCITMRVPRNPTIGDKFASRHGQKGILSRLWPAE 900
            YKSKENCVVDNIKVCSNDTGSGKFKCVCITMRVPRNPTIGDKFASRHGQKGILSRLWPAE
Sbjct: 785  YKSKENCVVDNIKVCSNDTGSGKFKCVCITMRVPRNPTIGDKFASRHGQKGILSRLWPAE 844

Query: 901  DMPFTESGMVPDILFNPHGFPSRMTIGMLIESMAGKSAALHGLCHDATPFIFSEENSALE 960
            DMPFTESGMVPDILFNPHGFPSRMTIGMLIESMAGKSAALHGLCHDATPFIFSEENSALE
Sbjct: 845  DMPFTESGMVPDILFNPHGFPSRMTIGMLIESMAGKSAALHGLCHDATPFIFSEENSALE 904

Query: 961  YFGEMLKAAGYNFYGTERLYSGISGLELEADIFIGVVYYQRLRHMVSDKFQVRTTGARDR 1020
            YFGEMLKAAGYNFYGTERLYSGISGLELEADIFIGVVYYQRLRHMVSDKFQVRTTGARDR
Sbjct: 905  YFGEMLKAAGYNFYGTERLYSGISGLELEADIFIGVVYYQRLRHMVSDKFQVRTTGARDR 964

Query: 1021 VTNQPIGGRNVQGGIRFGEMERDALLAHGTSFLLHDRLFNCSDRSVAHVCVKCGSLLSPL 1080
            VTNQPIGGRNVQGGIRFGEMERDALLAHGTSFLLHDRLFNCSDRSVAHVCVKCGSLLSPL
Sbjct: 965  VTNQPIGGRNVQGGIRFGEMERDALLAHGTSFLLHDRLFNCSDRSVAHVCVKCGSLLSPL 1024

Query: 1081 LEKPPPSWSAMRNRKYNCTLCSRSDTIDTVSVPYVFRYFVAELAAMNIKVKLDVV 1135
            LEKPPPSWSAMRNRKYNCTLCSRSDTIDTVSVPYVFRYFVAELAAMNIKVKLDVV
Sbjct: 1025 LEKPPPSWSAMRNRKYNCTLCSRSDTIDTVSVPYVFRYFVAELAAMNIKVKLDVV 1079


>gi|238908503 DNA-directed RNA polymerase III B isoform 1 [Homo
            sapiens]
          Length = 1133

 Score =  406 bits (1044), Expect = e-113
 Identities = 348/1153 (30%), Positives = 521/1153 (45%), Gaps = 123/1153 (10%)

Query: 38   LTRAHVESFNYAVHEGLGLAVQAIPPFEFAFKDERISFTILDAVISPPTVPKGTICKEAN 97
            L + H++SFNY ++  +   ++A      +  D       L+  +  P V +        
Sbjct: 39   LVKQHIDSFNYFINVEIKKIMKANEKVT-SDADPMWYLKYLNIYVGLPDVEESFNVTRP- 96

Query: 98   VYPAECRGRRSTYRGKLTADINWAVNGISKGIIKQFL--GYVPIMVKSKLCNLRNLPPQA 155
            V P ECR R  TY   +T DI +     S+ II+  L  G +PIM++S  C L    P  
Sbjct: 97   VSPHECRLRDMTYSAPITVDIEYTRG--SQRIIRNALPIGRMPIMLRSSNCVLTGKTPAE 154

Query: 156  LIEHHEEAEEMGGYFIINGIEKVIRMLIMPRRNFPIAMIRPKWKTRGPGYTQYGVSMHCV 215
              + +E   + GGYFI+ G+EKVI +     +N  I     K    G   T    S H  
Sbjct: 155  FAKLNECPLDPGGYFIVKGVEKVILIQEQLSKNRIIVEADRKGAV-GASVTS---STHEK 210

Query: 216  REE-HSAVNMNLHYLENGTVMLNFIYRKELFFLPLGFALKALVSFSDYQIFQELIKGKED 274
            +   + AV     YL + T+  +         +P+    KA+   SD +I Q +  G E+
Sbjct: 211  KSRTNMAVKQGRFYLRHNTLSED---------IPIVIIFKAMGVESDQEIVQMI--GTEE 259

Query: 275  DSFLRNSVSQMLRIVMEEGCSTQKQVLNYLGECFRVKL---NVPDWYPNEQAAEFLFNQC 331
               +  +    L    +    TQ Q L Y+G   R +      P     E+A E L +  
Sbjct: 260  H--VMAAFGPSLEECQKAQIFTQMQALKYIGNKVRRQRMWGGGPKKTKIEEARELLAST- 316

Query: 332  ICIHLKSNTEKFYMLCLMTRKLFA---LAKGECMEDNPDSLVNQEVLTPGQLFLMFLKEK 388
            I  H+      F   C+ T  +     LA+G+   D+ D   N+ +   GQL  +  ++ 
Sbjct: 317  ILTHVPVKEFNFRAKCIYTAVMVRRVILAQGDNKVDDRDYYGNKRLELAGQLLSLLFEDL 376

Query: 389  LEGWLVSIKIAFDKKAQKT-SVSMNTDNLMRIFTMGIDLTKPFEYLFATGNLRSKTGLGL 447
             + +   +K   D+   K  +   +    MR       +T       +TGN   K     
Sbjct: 377  FKKFNSEMKKIADQVIPKQRAAQFDVVKHMR----QDQITNGMVNAISTGNWSLKRFK-- 430

Query: 448  LQDSGLCVVADKLNFIRYLSHFRCVHRGADFAKMRTTT-VRRLLPESWGFLCPVHTPDGE 506
            +   G+  V  +L++I  L     +   + F K R  +  R L P  WG LCP  TP+GE
Sbjct: 431  MDRQGVTQVLSRLSYISALGMMTRI--SSQFEKTRKVSGPRSLQPSQWGMLCPSDTPEGE 488

Query: 507  PCGLMNHLTAVCEVVTQFVYTASIPALLCNLGVTPID--GAPHRSYSECYPVLLDGVMVG 564
             CGL+ +L  +  + T  +    I  L  NLGV  ++       SY   + V L+G ++G
Sbjct: 489  ACGLVKNLALMTHITTD-MEDGPIVKLASNLGVEDVNLLCGEELSYPNVFLVFLNGNILG 547

Query: 565  WVDKDLAPGIADSLRHFKVLREKRIPPWMEVVLIPMTGKPSLYPGLFLFTTPCRLVRP-- 622
             +           +  F+++R          +   +T +      +++ +   RL RP  
Sbjct: 548  VIRDH-----KKLVNTFRLMRRAGYINEFVSISTNLTDRC-----VYISSDGGRLCRPYI 597

Query: 623  -------------VQNLALGKE-----------ELIGTMEQIFMNVAIFEDEVFAGVTTH 658
                         ++ LA G             E +   E+   N+A++E  +    TTH
Sbjct: 598  IVKKQKPAVTNKHMEELAQGYRNFEDFLHESLVEYLDVNEENDCNIALYEHTINKD-TTH 656

Query: 659  QELFPHSLLSVIANFIPFSDHNQSPRNMYQCQMGKQTMGFPLLTYQDRSDNKLYRLQTPQ 718
             E+ P +LL V A  IP+  HNQSPRN YQC MGKQ MG      ++R D  +Y L  PQ
Sbjct: 657  LEIEPFTLLGVCAGLIPYPHHNQSPRNTYQCAMGKQAMGTIGYNQRNRIDTLMYLLAYPQ 716

Query: 719  SPLVRPSMYDYYDMDNYPIGTNAIVAVISYTGYDMEDAMIVNKASWERGFAHGSVYKSEF 778
             P+V+    +  + +  P G NA VAV+SY+GYD+EDA+++NKAS +RGF    VYK+  
Sbjct: 717  KPMVKTKTIELIEFEKLPAGQNATVAVMSYSGYDIEDALVLNKASLDRGFGRCLVYKNAK 776

Query: 779  IDLSEKIKQGDSSLVFGIKPGDPRVL----QKLDDDGLPFIGAKLQYGD-------PYYS 827
              L     Q    ++  +     R      + LD DG+   G K++          P  +
Sbjct: 777  CTLKRYTNQTFDKVMGPMLDAATRKPIWRHEILDADGICSPGEKVENKQVLVNKSMPTVT 836

Query: 828  YLNLNTG--------ESFVMYYKSKENCVVDNIKVCSNDTGSGKFKCVCITMRVPRNPTI 879
             + L           +   + YK   +  ++ + + SN   +   K +   +R  R P I
Sbjct: 837  QIPLEGSNVPQQPQYKDVPITYKGATDSYIEKVMISSNAEDAFLIKML---LRQTRRPEI 893

Query: 880  GDKFASRHGQKGILSRLWPAEDMPFTESGMVPDILFNPHGFPSRMTIGMLIESMAGKSAA 939
            GDKF+SRHGQKG+   + P EDMPF +SG+ PDI+ NPHGFPSRMT+G LIE +AGK+  
Sbjct: 894  GDKFSSRHGQKGVCGLIVPQEDMPFCDSGICPDIIMNPHGFPSRMTVGKLIELLAGKAGV 953

Query: 940  LHGLCHDATPFIFSEENSALEYFGEMLKAAGYNFYGTERLYSGISGLELEADIFIGVVYY 999
            L G  H  T F      S ++   E L   GYN+ G + + SGI+G  LEA I+ G VYY
Sbjct: 954  LDGRFHYGTAF----GGSKVKDVCEDLVRHGYNYLGKDYVTSGITGEPLEAYIYFGPVYY 1009

Query: 1000 QRLRHMVSDKFQVRTTGARDRVTNQPIGGRNVQGGIRFGEMERDALLAHGTSFLLHDRLF 1059
            Q+L+HMV DK   R  G R  +T QP  GR+  GG+R GEMERD L+ +G S LL +RL 
Sbjct: 1010 QKLKHMVLDKMHARARGPRAVLTRQPTEGRSRDGGLRLGEMERDCLIGYGASMLLLERLM 1069

Query: 1060 NCSDRSVAHVCVKCGSLLSPLLEKPPPSWSAMRNRKYNCTLCSRSDTIDTVSVPYVFRYF 1119
              SD     VC +CG L           W         C  C  S  + ++ +PY  +  
Sbjct: 1070 ISSDAFEVDVCGQCGLL-------GYSGW---------CHYCKSSCHVSSLRIPYACKLL 1113

Query: 1120 VAELAAMNIKVKL 1132
              EL +MNI  +L
Sbjct: 1114 FQELQSMNIIPRL 1126


>gi|238908505 DNA-directed RNA polymerase III B isoform 2 [Homo
            sapiens]
          Length = 1075

 Score =  402 bits (1034), Expect = e-112
 Identities = 337/1093 (30%), Positives = 498/1093 (45%), Gaps = 121/1093 (11%)

Query: 98   VYPAECRGRRSTYRGKLTADINWAVNGISKGIIKQFL--GYVPIMVKSKLCNLRNLPPQA 155
            V P ECR R  TY   +T DI +     S+ II+  L  G +PIM++S  C L    P  
Sbjct: 39   VSPHECRLRDMTYSAPITVDIEYTRG--SQRIIRNALPIGRMPIMLRSSNCVLTGKTPAE 96

Query: 156  LIEHHEEAEEMGGYFIINGIEKVIRMLIMPRRNFPIAMIRPKWKTRGPGYTQYGVSMHCV 215
              + +E   + GGYFI+ G+EKVI +     +N  I     K    G   T    S H  
Sbjct: 97   FAKLNECPLDPGGYFIVKGVEKVILIQEQLSKNRIIVEADRKGAV-GASVTS---STHEK 152

Query: 216  REE-HSAVNMNLHYLENGTVMLNFIYRKELFFLPLGFALKALVSFSDYQIFQELIKGKED 274
            +   + AV     YL + T+  +         +P+    KA+   SD +I Q +  G E+
Sbjct: 153  KSRTNMAVKQGRFYLRHNTLSED---------IPIVIIFKAMGVESDQEIVQMI--GTEE 201

Query: 275  DSFLRNSVSQMLRIVMEEGCSTQKQVLNYLGECFRVKL---NVPDWYPNEQAAEFLFNQC 331
               +  +    L    +    TQ Q L Y+G   R +      P     E+A E L +  
Sbjct: 202  H--VMAAFGPSLEECQKAQIFTQMQALKYIGNKVRRQRMWGGGPKKTKIEEARELLAST- 258

Query: 332  ICIHLKSNTEKFYMLCLMTRKLFA---LAKGECMEDNPDSLVNQEVLTPGQLFLMFLKEK 388
            I  H+      F   C+ T  +     LA+G+   D+ D   N+ +   GQL  +  ++ 
Sbjct: 259  ILTHVPVKEFNFRAKCIYTAVMVRRVILAQGDNKVDDRDYYGNKRLELAGQLLSLLFEDL 318

Query: 389  LEGWLVSIKIAFDKKAQKT-SVSMNTDNLMRIFTMGIDLTKPFEYLFATGNLRSKTGLGL 447
             + +   +K   D+   K  +   +    MR       +T       +TGN   K     
Sbjct: 319  FKKFNSEMKKIADQVIPKQRAAQFDVVKHMR----QDQITNGMVNAISTGNWSLKRFK-- 372

Query: 448  LQDSGLCVVADKLNFIRYLSHFRCVHRGADFAKMRTTT-VRRLLPESWGFLCPVHTPDGE 506
            +   G+  V  +L++I  L     +   + F K R  +  R L P  WG LCP  TP+GE
Sbjct: 373  MDRQGVTQVLSRLSYISALGMMTRI--SSQFEKTRKVSGPRSLQPSQWGMLCPSDTPEGE 430

Query: 507  PCGLMNHLTAVCEVVTQFVYTASIPALLCNLGVTPID--GAPHRSYSECYPVLLDGVMVG 564
             CGL+ +L  +  + T  +    I  L  NLGV  ++       SY   + V L+G ++G
Sbjct: 431  ACGLVKNLALMTHITTD-MEDGPIVKLASNLGVEDVNLLCGEELSYPNVFLVFLNGNILG 489

Query: 565  WVDKDLAPGIADSLRHFKVLREKRIPPWMEVVLIPMTGKPSLYPGLFLFTTPCRLVRP-- 622
             +           +  F+++R          +   +T +      +++ +   RL RP  
Sbjct: 490  VIRDH-----KKLVNTFRLMRRAGYINEFVSISTNLTDRC-----VYISSDGGRLCRPYI 539

Query: 623  -------------VQNLALGKE-----------ELIGTMEQIFMNVAIFEDEVFAGVTTH 658
                         ++ LA G             E +   E+   N+A++E  +    TTH
Sbjct: 540  IVKKQKPAVTNKHMEELAQGYRNFEDFLHESLVEYLDVNEENDCNIALYEHTINKD-TTH 598

Query: 659  QELFPHSLLSVIANFIPFSDHNQSPRNMYQCQMGKQTMGFPLLTYQDRSDNKLYRLQTPQ 718
             E+ P +LL V A  IP+  HNQSPRN YQC MGKQ MG      ++R D  +Y L  PQ
Sbjct: 599  LEIEPFTLLGVCAGLIPYPHHNQSPRNTYQCAMGKQAMGTIGYNQRNRIDTLMYLLAYPQ 658

Query: 719  SPLVRPSMYDYYDMDNYPIGTNAIVAVISYTGYDMEDAMIVNKASWERGFAHGSVYKSEF 778
             P+V+    +  + +  P G NA VAV+SY+GYD+EDA+++NKAS +RGF    VYK+  
Sbjct: 659  KPMVKTKTIELIEFEKLPAGQNATVAVMSYSGYDIEDALVLNKASLDRGFGRCLVYKNAK 718

Query: 779  IDLSEKIKQGDSSLVFGIKPGDPRVL----QKLDDDGLPFIGAKLQYGD-------PYYS 827
              L     Q    ++  +     R      + LD DG+   G K++          P  +
Sbjct: 719  CTLKRYTNQTFDKVMGPMLDAATRKPIWRHEILDADGICSPGEKVENKQVLVNKSMPTVT 778

Query: 828  YLNLNTG--------ESFVMYYKSKENCVVDNIKVCSNDTGSGKFKCVCITMRVPRNPTI 879
             + L           +   + YK   +  ++ + + SN   +   K +   +R  R P I
Sbjct: 779  QIPLEGSNVPQQPQYKDVPITYKGATDSYIEKVMISSNAEDAFLIKML---LRQTRRPEI 835

Query: 880  GDKFASRHGQKGILSRLWPAEDMPFTESGMVPDILFNPHGFPSRMTIGMLIESMAGKSAA 939
            GDKF+SRHGQKG+   + P EDMPF +SG+ PDI+ NPHGFPSRMT+G LIE +AGK+  
Sbjct: 836  GDKFSSRHGQKGVCGLIVPQEDMPFCDSGICPDIIMNPHGFPSRMTVGKLIELLAGKAGV 895

Query: 940  LHGLCHDATPFIFSEENSALEYFGEMLKAAGYNFYGTERLYSGISGLELEADIFIGVVYY 999
            L G  H  T F      S ++   E L   GYN+ G + + SGI+G  LEA I+ G VYY
Sbjct: 896  LDGRFHYGTAF----GGSKVKDVCEDLVRHGYNYLGKDYVTSGITGEPLEAYIYFGPVYY 951

Query: 1000 QRLRHMVSDKFQVRTTGARDRVTNQPIGGRNVQGGIRFGEMERDALLAHGTSFLLHDRLF 1059
            Q+L+HMV DK   R  G R  +T QP  GR+  GG+R GEMERD L+ +G S LL +RL 
Sbjct: 952  QKLKHMVLDKMHARARGPRAVLTRQPTEGRSRDGGLRLGEMERDCLIGYGASMLLLERLM 1011

Query: 1060 NCSDRSVAHVCVKCGSLLSPLLEKPPPSWSAMRNRKYNCTLCSRSDTIDTVSVPYVFRYF 1119
              SD     VC +CG L           W         C  C  S  + ++ +PY  +  
Sbjct: 1012 ISSDAFEVDVCGQCGLL-------GYSGW---------CHYCKSSCHVSSLRIPYACKLL 1055

Query: 1120 VAELAAMNIKVKL 1132
              EL +MNI  +L
Sbjct: 1056 FQELQSMNIIPRL 1068


>gi|4505941 DNA directed RNA polymerase II polypeptide B [Homo
            sapiens]
          Length = 1174

 Score =  383 bits (983), Expect = e-106
 Identities = 330/1116 (29%), Positives = 492/1116 (44%), Gaps = 137/1116 (12%)

Query: 100  PAECRGRRSTYRGKLTADINWAV-----NGISKGIIKQFLGYVPIMVKSKLCNLRNLPPQ 154
            P E R R  TY   L  DI   V       +     K F+G +PIM++S  C L  L  +
Sbjct: 110  PNEARLRNLTYSAPLYVDITKTVIKEGEEQLQTQHQKTFIGKIPIMLRSTYCLLNGLTDR 169

Query: 155  ALIEHHEEAEEMGGYFIINGIEKVIRMLIMPRRNFPIAMIRPKWKTRGPGYTQYGVSMHC 214
             L E +E   + GGYFIING EKV+        N      +   K     Y   G    C
Sbjct: 170  DLCELNECPLDPGGYFIINGSEKVLIAQEKMATNTVYVFAKKDSK-----YAYTGECRSC 224

Query: 215  VREEHSAVN-MNLHYLENG-----------TVMLNFIYRKELFFLPLGFALKALVSFSDY 262
            +       + + +  L  G            ++    Y K+   +P+    +AL   SD 
Sbjct: 225  LENSSRPTSTIWVSMLARGGQGAKKSAIGQRIVATLPYIKQE--VPIIIVFRALGFVSDR 282

Query: 263  QIFQELIKGKEDDSFLRNSVSQMLRIVMEEGCSTQKQ--VLNYLGECFRVKLNVPDWYPN 320
             I + +I   ED   +     +M++  ++E    Q+Q   LN++G     K  V      
Sbjct: 283  DILEHIIYDFEDPEMM-----EMVKPSLDEAFVIQEQNVALNFIGSR-GAKPGVTKEKRI 336

Query: 321  EQAAEFLFNQC---ICIHLKSNTEKFYMLCLMTRKLFALAKGECMEDNPDSLVNQEVLTP 377
            + A E L  +    + +     T+K Y L  M  +L   A G    D+ D   N+ +   
Sbjct: 337  KYAKEVLQKEMLPHVGVSDFCETKKAYFLGYMVHRLLLAALGRRELDDRDHYGNKRLDLA 396

Query: 378  GQLFLMFLKEKLEGWLVSIKIAFDKKAQK-TSVSMNTDNLMRIFTMGIDLTKPFEYLFAT 436
            G L     +   +  L  ++I   K   +    ++      RI + G+      +Y  AT
Sbjct: 397  GPLLAFLFRGMFKNLLKEVRIYAQKFIDRGKDFNLELAIKTRIISDGL------KYSLAT 450

Query: 437  GNLRSKTGLGLLQDSGLCVVADKLNFIRYLSHFRCVH----RGADFAKMRTTTVRRLLPE 492
            GN   +      + +G+  V ++L F   LSH R ++    R    AK R     +L   
Sbjct: 451  GNWGDQKKAHQAR-AGVSQVLNRLTFASTLSHLRRLNSPIGRDGKLAKPR-----QLHNT 504

Query: 493  SWGFLCPVHTPDGEPCGLMNHLTAVCEVVTQFVYTASIPALLCNLGVTPIDGAPHRSYSE 552
             WG +CP  TP+G   GL+ +L A+   ++     + I   L    +  ++     + ++
Sbjct: 505  LWGMVCPAETPEGHAVGLVKNL-ALMAYISVGSQPSPILEFLEEWSMENLEEISPAAIAD 563

Query: 553  CYPVLLDGVMVGWVDKDLAPGIADSLRHFKVLREKRIPPWMEVVLIPMTGKPSLYPGLFL 612
               + ++G  VG + KD    + ++LR    LR +      EV +I    +  +     +
Sbjct: 564  ATKIFVNGCWVG-IHKD-PEQLMNTLRK---LRRQMDIIVSEVSMIRDIREREIR----I 614

Query: 613  FTTPCRLVRPV-----QNLALGKE------------------------ELIGTMEQIFMN 643
            +T   R+ RP+     Q L L K                         E I T+E+  + 
Sbjct: 615  YTDAGRICRPLLIVEKQKLLLKKRHIDQLKEREYNNYSWQDLVASGVVEYIDTLEEETVM 674

Query: 644  VAIFEDEV------FAGVTTHQELFPHSLLSVIANFIPFSDHNQSPRNMYQCQMGKQTMG 697
            +A+  D++      +    TH E+ P  +L V A+ IPF DHNQSPRN YQ  MGKQ MG
Sbjct: 675  LAMTPDDLQEKEVAYCSTYTHCEIHPSMILGVCASIIPFPDHNQSPRNTYQSAMGKQAMG 734

Query: 698  FPLLTYQDRSDNKLYRLQTPQSPLVRPSMYDYYDMDNYPIGTNAIVAVISYTGYDMEDAM 757
              +  +  R D   + L  PQ PLV     +Y      P G N+IVA+ SYTGY+ ED++
Sbjct: 735  VYITNFHVRMDTLAHVLYYPQKPLVTTRSMEYLRFRELPAGINSIVAIASYTGYNQEDSV 794

Query: 758  IVNKASWERGFAHGSVYKS-------EFIDLSEKIKQGDSSLVFGIKPGDPRVLQKLDDD 810
            I+N+++ +RGF     Y+S       +  D  E  ++       G++     +  KLDDD
Sbjct: 795  IMNRSAVDRGFFRSVFYRSYKEQESKKGFDQEEVFEKPTRETCQGMRHA---IYDKLDDD 851

Query: 811  GLPFIGAKL--------------QYGDPYYSYLNLNTGESFVMYYKSKENCVVDNIKVCS 856
            GL   G ++              +  D   S     T      + ++ E  +VD + V  
Sbjct: 852  GLIAPGVRVSGDDVIIGKTVTLPENEDELESTNRRYTKRDCSTFLRTSETGIVDQVMVTL 911

Query: 857  NDTGSGKFKCVCITMRVPRNPTIGDKFASRHGQKGILSRLWPAEDMPFTESGMVPDILFN 916
            N  G   +K   I +R  R P IGDKFASRHGQKG     +  EDMPFT  G+ PDI+ N
Sbjct: 912  NQEG---YKFCKIRVRSVRIPQIGDKFASRHGQKGTCGIQYRQEDMPFTCEGITPDIIIN 968

Query: 917  PHGFPSRMTIGMLIESMAGKSAALHGLCHDATPFIFSEENSALEYFGEMLKAAGYNFYGT 976
            PH  PSRMTIG LIE + GK +A  G   DATPF    +   ++    +L   GY+  G 
Sbjct: 969  PHAIPSRMTIGHLIECLQGKVSANKGEIGDATPF---NDAVNVQKISNLLSDYGYHLRGN 1025

Query: 977  ERLYSGISGLELEADIFIGVVYYQRLRHMVSDKFQVRTTGARDRVTNQPIGGRNVQGGIR 1036
            E LY+G +G ++ + IFIG  YYQRL+HMV DK   R  G    +  QP+ GR+  GG+R
Sbjct: 1026 EVLYNGFTGRKITSQIFIGPTYYQRLKHMVDDKIHSRARGPIQILNRQPMEGRSRDGGLR 1085

Query: 1037 FGEMERDALLAHGTSFLLHDRLFNCSDRSVAHVCVKCGSLLSPLLEKPPPSWSAMRNRKY 1096
            FGEMERD  +AHG +  L +RLF  SD    HVC  CG +          + +  R   Y
Sbjct: 1086 FGEMERDCQIAHGAAQFLRERLFEASDPYQVHVCNLCGIM----------AIANTRTHTY 1135

Query: 1097 NCTLCSRSDTIDTVSVPYVFRYFVAELAAMNIKVKL 1132
             C  C     I  V +PY  +    EL +M+I  ++
Sbjct: 1136 ECRGCRNKTQISLVRMPYACKLLFQELMSMSIAPRM 1171


>gi|61742777 leucyl/cystinyl aminopeptidase isoform 1 [Homo sapiens]
          Length = 1025

 Score = 35.8 bits (81), Expect = 0.24
 Identities = 33/149 (22%), Positives = 61/149 (40%), Gaps = 11/149 (7%)

Query: 591 PWMEVVL----IPMTGKPSLYPGLFLFTTPCRLVRPVQNLALGKEELIGT----MEQIFM 642
           PW ++ L    +P+  + SL+P L   T    +   VQ L +    ++ +    + ++  
Sbjct: 162 PWAQIRLPTAVVPLRYELSLHPNLTSMTFRGSVTISVQALQVTWNIILHSTGHNISRVTF 221

Query: 643 NVAIFEDEVFAGVTTHQELFPHSLLSVIANFIPFSDHNQSPRNMYQCQMGKQTMGFPLLT 702
             A+   E  A +    E   H  ++++A     + HN + +  Y   +     GF   +
Sbjct: 222 MSAVSSQEKQAEIL---EYAYHGQIAIVAPEALLAGHNYTLKIEYSANISSSYYGFYGFS 278

Query: 703 YQDRSDNKLYRLQTPQSPLVRPSMYDYYD 731
           Y D S+ K Y   T   PL   S +  +D
Sbjct: 279 YTDESNEKKYFAATQFEPLAARSAFPCFD 307


>gi|61742775 leucyl/cystinyl aminopeptidase isoform 2 [Homo sapiens]
          Length = 1011

 Score = 35.8 bits (81), Expect = 0.24
 Identities = 33/149 (22%), Positives = 61/149 (40%), Gaps = 11/149 (7%)

Query: 591 PWMEVVL----IPMTGKPSLYPGLFLFTTPCRLVRPVQNLALGKEELIGT----MEQIFM 642
           PW ++ L    +P+  + SL+P L   T    +   VQ L +    ++ +    + ++  
Sbjct: 148 PWAQIRLPTAVVPLRYELSLHPNLTSMTFRGSVTISVQALQVTWNIILHSTGHNISRVTF 207

Query: 643 NVAIFEDEVFAGVTTHQELFPHSLLSVIANFIPFSDHNQSPRNMYQCQMGKQTMGFPLLT 702
             A+   E  A +    E   H  ++++A     + HN + +  Y   +     GF   +
Sbjct: 208 MSAVSSQEKQAEIL---EYAYHGQIAIVAPEALLAGHNYTLKIEYSANISSSYYGFYGFS 264

Query: 703 YQDRSDNKLYRLQTPQSPLVRPSMYDYYD 731
           Y D S+ K Y   T   PL   S +  +D
Sbjct: 265 YTDESNEKKYFAATQFEPLAARSAFPCFD 293


>gi|96975023 ankyrin repeat and death domain containing 1A [Homo
           sapiens]
          Length = 522

 Score = 30.8 bits (68), Expect = 7.6
 Identities = 22/80 (27%), Positives = 40/80 (50%), Gaps = 10/80 (12%)

Query: 743 VAVISYTGYDMEDAMI-----VNKASWERGFAHGSVYKSEFI-----DLSEKIKQGDSSL 792
           V V+++   D+ED  +     + + ++ R   HG +   +F+     D + K K+G+++L
Sbjct: 137 VPVLAFIMEDLEDVALDHVDKLGRTAFHRAAEHGQLDALDFLVGSGCDHNVKDKEGNTAL 196

Query: 793 VFGIKPGDPRVLQKLDDDGL 812
                 G   VLQ+L D GL
Sbjct: 197 HLAAGRGHMAVLQRLVDIGL 216


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.323    0.139    0.428 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 44,499,691
Number of Sequences: 37866
Number of extensions: 2049203
Number of successful extensions: 3656
Number of sequences better than 10.0: 8
Number of HSP's better than 10.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 1
Number of HSP's that attempted gapping in prelim test: 3628
Number of HSP's gapped (non-prelim): 15
length of query: 1135
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1022
effective length of database: 13,968,660
effective search space: 14275970520
effective search space used: 14275970520
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.