Guide to the Human Genome
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Search of human proteins with 33457326

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|33457326 GS homeobox 1 [Homo sapiens]
         (264 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|33457326 GS homeobox 1 [Homo sapiens]                              547   e-156
gi|18959212 GS homeobox 2 [Homo sapiens]                              213   1e-55
gi|4557673 pancreatic and duodenal homeobox 1 [Homo sapiens]          102   3e-22
gi|13273315 homeobox B4 [Homo sapiens]                                100   1e-21
gi|10140847 homeobox A2 [Homo sapiens]                                 99   5e-21
gi|19923391 homeobox D3 [Homo sapiens]                                 96   2e-20
gi|89257348 homeo box HB9 [Homo sapiens]                               96   3e-20
gi|24497515 homeobox A3 isoform b [Homo sapiens]                       95   5e-20
gi|24497513 homeobox A3 isoform a [Homo sapiens]                       95   5e-20
gi|13562112 homeobox A3 isoform a [Homo sapiens]                       95   5e-20
gi|84570137 homeobox B3 [Homo sapiens]                                 95   5e-20
gi|148613882 homeobox A4 [Homo sapiens]                                95   7e-20
gi|239748344 PREDICTED: NK1 homeobox 1 [Homo sapiens]                  94   1e-19
gi|239753784 PREDICTED: NK1 homeobox 1 [Homo sapiens]                  91   8e-19
gi|4504469 homeobox B5 [Homo sapiens]                                  89   3e-18
gi|23397672 homeobox D4 [Homo sapiens]                                 89   4e-18
gi|4504465 homeobox B2 [Homo sapiens]                                  89   5e-18
gi|239742243 PREDICTED: HPX-153 homeobox [Homo sapiens]                88   7e-18
gi|24497538 homeobox C4 [Homo sapiens]                                 87   2e-17
gi|24497540 homeobox C4 [Homo sapiens]                                 87   2e-17
gi|24497517 homeobox A5 [Homo sapiens]                                 86   4e-17
gi|11321638 homeobox C5 [Homo sapiens]                                 86   4e-17
gi|24497556 homeobox A7 [Homo sapiens]                                 85   7e-17
gi|24497544 homeobox C6 isoform 2 [Homo sapiens]                       81   8e-16
gi|4758554 homeobox C6 isoform 1 [Homo sapiens]                        81   8e-16
gi|226437602 NK1 homeobox 2 [Homo sapiens]                             80   1e-15
gi|239755439 PREDICTED: NK1 homeobox 2 [Homo sapiens]                  80   1e-15
gi|239749920 PREDICTED: NK1 homeobox 2 [Homo sapiens]                  80   1e-15
gi|239744223 PREDICTED: NK1 homeobox 2 [Homo sapiens]                  80   1e-15
gi|24497526 homeobox B1 [Homo sapiens]                                 80   1e-15

>gi|33457326 GS homeobox 1 [Homo sapiens]
          Length = 264

 Score =  547 bits (1409), Expect = e-156
 Identities = 264/264 (100%), Positives = 264/264 (100%)

Query: 1   MPRSFLVDSLVLREAGEKKAPEGSPPPLFPYAVPPPHALHGLSPGACHARKAGLLCVCPL 60
           MPRSFLVDSLVLREAGEKKAPEGSPPPLFPYAVPPPHALHGLSPGACHARKAGLLCVCPL
Sbjct: 1   MPRSFLVDSLVLREAGEKKAPEGSPPPLFPYAVPPPHALHGLSPGACHARKAGLLCVCPL 60

Query: 61  CVTASQLHGPPGPPALPLLKASFPPFGSQYCHAPLGRQHSAVSPGVAHGPAAAAAAAALY 120
           CVTASQLHGPPGPPALPLLKASFPPFGSQYCHAPLGRQHSAVSPGVAHGPAAAAAAAALY
Sbjct: 61  CVTASQLHGPPGPPALPLLKASFPPFGSQYCHAPLGRQHSAVSPGVAHGPAAAAAAAALY 120

Query: 121 QTSYPLPDPRQFHCISVDSSSNQLPSSKRMRTAFTSTQLLELEREFASNMYLSRLRRIEI 180
           QTSYPLPDPRQFHCISVDSSSNQLPSSKRMRTAFTSTQLLELEREFASNMYLSRLRRIEI
Sbjct: 121 QTSYPLPDPRQFHCISVDSSSNQLPSSKRMRTAFTSTQLLELEREFASNMYLSRLRRIEI 180

Query: 181 ATYLNLSEKQVKIWFQNRRVKHKKEGKGSNHRGGGGGGAGGGGSAPQGCKCASLSSAKCS 240
           ATYLNLSEKQVKIWFQNRRVKHKKEGKGSNHRGGGGGGAGGGGSAPQGCKCASLSSAKCS
Sbjct: 181 ATYLNLSEKQVKIWFQNRRVKHKKEGKGSNHRGGGGGGAGGGGSAPQGCKCASLSSAKCS 240

Query: 241 EDDDELPMSPSSSGKDDRDLTVTP 264
           EDDDELPMSPSSSGKDDRDLTVTP
Sbjct: 241 EDDDELPMSPSSSGKDDRDLTVTP 264


>gi|18959212 GS homeobox 2 [Homo sapiens]
          Length = 304

 Score =  213 bits (542), Expect = 1e-55
 Identities = 142/318 (44%), Positives = 176/318 (55%), Gaps = 73/318 (22%)

Query: 1   MPRSFLVDSLVLREAGEK--KAPEGSPPPLF--PYAVPPPHALHGLSPGACHARKAGLLC 56
           M RSF VDSL++++        PE  P P F  P  +PPP  +    PG C +RK+G  C
Sbjct: 1   MSRSFYVDSLIIKDTSRPAPSLPEPHPGPDFFIPLGMPPPLVMSVSGPG-CPSRKSGAFC 59

Query: 57  VCPLCVTASQLHGPPGPP------------------------ALPLLKASFP--PFGSQY 90
           VCPLCVT S LH   G                          ALPLLK+ F   P  +Q+
Sbjct: 60  VCPLCVT-SHLHSSRGSVGAGSGGAGAGVTGAGGSGVAGAAGALPLLKSQFSSAPGDAQF 118

Query: 91  C----------HAPLGRQH--SAVSPGVAHGPAAAAAAAALYQ--------------TSY 124
           C          H P    H      PG A   AAAAAAAA                 T+Y
Sbjct: 119 CPRVNHAHHHHHPPQHHHHHHQPQQPGSAAAAAAAAAAAAAAAALGHPQHHAPVCTATTY 178

Query: 125 PLPDPRQFHCISVDSS-SNQLPSSKRMRTAFTSTQLLELEREFASNMYLSRLRRIEIATY 183
            + DPR+FHC+++  S ++Q+P+ KRMRTAFTSTQLLELEREF+SNMYLSRLRRIEIATY
Sbjct: 179 NVADPRRFHCLTMGGSDASQVPNGKRMRTAFTSTQLLELEREFSSNMYLSRLRRIEIATY 238

Query: 184 LNLSEKQVKIWFQNRRVKHKKEGKGSNHRGGGGGGAGGGGSAPQGCKCASLSSAKCSEDD 243
           LNLSEKQVKIWFQNRRVKHKKEGKG+              ++  GCKC   S    +  +
Sbjct: 239 LNLSEKQVKIWFQNRRVKHKKEGKGTQR------------NSHAGCKCVG-SQVHYARSE 285

Query: 244 DELPMSPSSSGKDDRDLT 261
           DE  +SP+S+  DD++++
Sbjct: 286 DEDSLSPASA-NDDKEIS 302


>gi|4557673 pancreatic and duodenal homeobox 1 [Homo sapiens]
          Length = 283

 Score =  102 bits (254), Expect = 3e-22
 Identities = 80/237 (33%), Positives = 99/237 (41%), Gaps = 53/237 (22%)

Query: 22  EGSPPPLFPYAVPPPHALHGLSPGACHARKAGLLCVCPLCVTASQLHGPPGPPALPLLKA 81
           +GSPP + PY VPP        P   H                   H  P   ALP    
Sbjct: 59  QGSPPDISPYEVPPLAD----DPAVAHLH-----------------HHLPAQLALP---- 93

Query: 82  SFPPFGSQYCHAPLGRQHSAVSPGVAHGPAAAAAAAALYQTSYPLPDPRQFHCISVDSSS 141
                     H P G       PGV   P          Q  +P     + H      + 
Sbjct: 94  ----------HPPAGPFPEGAEPGVLEEPNRV-------QLPFPWMKSTKAHAWKGQWAG 136

Query: 142 NQLPS----SKRMRTAFTSTQLLELEREFASNMYLSRLRRIEIATYLNLSEKQVKIWFQN 197
               +    +KR RTA+T  QLLELE+EF  N Y+SR RR+E+A  LNL+E+ +KIWFQN
Sbjct: 137 GAYAAEPEENKRTRTAYTRAQLLELEKEFLFNKYISRPRRVELAVMLNLTERHIKIWFQN 196

Query: 198 RRVKHKKEGKGSNHRGGGGGGAGGGGSAPQGCKCASLSSAKCSEDDDELPMSPSSSG 254
           RR+K KKE    + + GGG   GGGG A     CA  S     E+   LP  P   G
Sbjct: 197 RRMKWKKE---EDKKRGGGTAVGGGGVAEPEQDCAVTS----GEELLALPPPPPPGG 246


>gi|13273315 homeobox B4 [Homo sapiens]
          Length = 251

 Score =  100 bits (249), Expect = 1e-21
 Identities = 77/204 (37%), Positives = 95/204 (46%), Gaps = 34/204 (16%)

Query: 23  GSPPPLFPYAVPPPHALHGLSPGACHARKAGLLCVCPLCVTASQLHGPPGPPALPLLKAS 82
           G PPP  P   PPP    GLSP A                       P  PPA  LL   
Sbjct: 72  GPPPP--PPPPPPPPPPPGLSPRA-----------------------PAPPPAGALL--- 103

Query: 83  FPPFGSQYCHAPLGRQHSAVSPGVAHGPAAAAAAAALYQTSYPLPDPRQFHCISVDSSSN 142
             P   Q C A      S   P  A  P   + + +  +     P  R+ H +S  + + 
Sbjct: 104 --PEPGQRCEAV---SSSPPPPPCAQNPLHPSPSHSACKEPVVYPWMRKVH-VSTVNPNY 157

Query: 143 QLPSSKRMRTAFTSTQLLELEREFASNMYLSRLRRIEIATYLNLSEKQVKIWFQNRRVKH 202
                KR RTA+T  Q+LELE+EF  N YL+R RR+EIA  L LSE+Q+KIWFQNRR+K 
Sbjct: 158 AGGEPKRSRTAYTRQQVLELEKEFHYNRYLTRRRRVEIAHALCLSERQIKIWFQNRRMKW 217

Query: 203 KKEGKGSNHRGGGGGGAGGGGSAP 226
           KK+ K  N +   GG AG  G  P
Sbjct: 218 KKDHKLPNTKIRSGGAAGSAGGPP 241


>gi|10140847 homeobox A2 [Homo sapiens]
          Length = 376

 Score = 98.6 bits (244), Expect = 5e-21
 Identities = 68/215 (31%), Positives = 101/215 (46%), Gaps = 36/215 (16%)

Query: 33  VPPP--HALHGLSPGACHARKAGLLCVCPLCVTASQLHGPPGPPALPLLKASFPPFGSQY 90
           +PPP    +  L+PG+     AG                P G    P+   +  P    +
Sbjct: 48  IPPPFEQTIPSLNPGSHPRHGAG----------GRPKPSPAGSRGSPVPAGALQPPEYPW 97

Query: 91  CHAPLGRQHSAVSPGVAHGPAAAAAAAALYQTSYPLPDPRQFHCISVDSSSNQLPSSKRM 150
                  + +A+ P  A    AAA   A              H  S++ +      S+R+
Sbjct: 98  MKEKKAAKKTALLPAAAAAATAAATGPACLS-----------HKESLEIADGSGGGSRRL 146

Query: 151 RTAFTSTQLLELEREFASNMYLSRLRRIEIATYLNLSEKQVKIWFQNRRVKHKKEGKGSN 210
           RTA+T+TQLLELE+EF  N YL R RR+EIA  L+L+E+QVK+WFQNRR+KHK++ +   
Sbjct: 147 RTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQTQCKE 206

Query: 211 HRGGGGGGAGGGGSAPQGCKCASLSSAKCSEDDDE 245
           ++   G             KC SL  ++  E+D+E
Sbjct: 207 NQNSEG-------------KCKSLEDSEKVEEDEE 228


>gi|19923391 homeobox D3 [Homo sapiens]
          Length = 432

 Score = 96.3 bits (238), Expect = 2e-20
 Identities = 63/155 (40%), Positives = 87/155 (56%), Gaps = 24/155 (15%)

Query: 65  SQLHGPPGPPALPLLKASFP--PFGSQYCHAPLGRQHSAVSPGVAHGPAAAAAAAALYQT 122
           S+   P  PP  P L  S P  P G      P G            GP A++++A + + 
Sbjct: 112 SEQQPPQPPPPPPTLPPSSPTNPGGGVPAKKPKG------------GPNASSSSATISKQ 159

Query: 123 SYP-LPDPRQFH-----CI----SVDSSSNQLPSSKRMRTAFTSTQLLELEREFASNMYL 172
            +P + + RQ       C     S +  S   P+SKR+RTA+TS QL+ELE+EF  N YL
Sbjct: 160 IFPWMKESRQNSKQKNSCATAGESCEDKSPPGPASKRVRTAYTSAQLVELEKEFHFNRYL 219

Query: 173 SRLRRIEIATYLNLSEKQVKIWFQNRRVKHKKEGK 207
            R RR+E+A  LNL+E+Q+KIWFQNRR+K+KK+ K
Sbjct: 220 CRPRRVEMANLLNLTERQIKIWFQNRRMKYKKDQK 254


>gi|89257348 homeo box HB9 [Homo sapiens]
          Length = 401

 Score = 95.9 bits (237), Expect = 3e-20
 Identities = 85/225 (37%), Positives = 104/225 (46%), Gaps = 36/225 (16%)

Query: 36  PHALHGLSPGACHARKAGLLCVCPLCVTASQLH--GPPGPPALPLLKASF--PPFG--SQ 89
           PH  H   PGA  A  A         + A  LH  G  G   LP   A +  P +G  + 
Sbjct: 113 PH--HHAHPGAAAAAAAAAAAAAAGGL-ALGLHPGGAQGGAGLPAQAALYGHPVYGYSAA 169

Query: 90  YCHAPLGRQHSAVS---PGV-----AHGPAAAAAAAALYQ---------TSYPLPDPRQF 132
              A L  QH A+S   P V     AH        A  +Q             LP    F
Sbjct: 170 AAAAALAGQHPALSYSYPQVQGAHPAHPADPIKLGAGTFQLDQWLRASTAGMILPKMPDF 229

Query: 133 HCISVDSSSNQLPSSKRMRTAFTSTQLLELEREFASNMYLSRLRRIEIATYLNLSEKQVK 192
           +     + SN L   +R RTAFTS QLLELE +F  N YLSR +R E+AT L L+E QVK
Sbjct: 230 NS---QAQSNLLGKCRRPRTAFTSQQLLELEHQFKLNKYLSRPKRFEVATSLMLTETQVK 286

Query: 193 IWFQNRRVKHKKEGKG-------SNHRGGGGGGAGGGGSAPQGCK 230
           IWFQNRR+K K+  K        +  + GGGGGAG GG+   G +
Sbjct: 287 IWFQNRRMKWKRSKKAKEQAAQEAEKQKGGGGGAGKGGAEEPGAE 331



 Score = 28.5 bits (62), Expect = 6.3
 Identities = 14/34 (41%), Positives = 16/34 (47%)

Query: 213 GGGGGGAGGGGSAPQGCKCASLSSAKCSEDDDEL 246
           G GGGG GGG S      C+  SS   +   D L
Sbjct: 40  GTGGGGGGGGASGGTSGSCSPASSEPPAAPADRL 73


>gi|24497515 homeobox A3 isoform b [Homo sapiens]
          Length = 285

 Score = 95.1 bits (235), Expect = 5e-20
 Identities = 48/91 (52%), Positives = 60/91 (65%)

Query: 138 DSSSNQLPSSKRMRTAFTSTQLLELEREFASNMYLSRLRRIEIATYLNLSEKQVKIWFQN 197
           D S     SSKR RTA+TS QL+ELE+EF  N YL R RR+E+A  LNL+E+Q+KIWFQN
Sbjct: 24  DKSPPGQASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQN 83

Query: 198 RRVKHKKEGKGSNHRGGGGGGAGGGGSAPQG 228
           RR+K+KK+ KG       GG +      P G
Sbjct: 84  RRMKYKKDQKGKGMLTSSGGQSPSRSPVPPG 114


>gi|24497513 homeobox A3 isoform a [Homo sapiens]
          Length = 443

 Score = 95.1 bits (235), Expect = 5e-20
 Identities = 48/91 (52%), Positives = 60/91 (65%)

Query: 138 DSSSNQLPSSKRMRTAFTSTQLLELEREFASNMYLSRLRRIEIATYLNLSEKQVKIWFQN 197
           D S     SSKR RTA+TS QL+ELE+EF  N YL R RR+E+A  LNL+E+Q+KIWFQN
Sbjct: 182 DKSPPGQASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQN 241

Query: 198 RRVKHKKEGKGSNHRGGGGGGAGGGGSAPQG 228
           RR+K+KK+ KG       GG +      P G
Sbjct: 242 RRMKYKKDQKGKGMLTSSGGQSPSRSPVPPG 272


>gi|13562112 homeobox A3 isoform a [Homo sapiens]
          Length = 443

 Score = 95.1 bits (235), Expect = 5e-20
 Identities = 48/91 (52%), Positives = 60/91 (65%)

Query: 138 DSSSNQLPSSKRMRTAFTSTQLLELEREFASNMYLSRLRRIEIATYLNLSEKQVKIWFQN 197
           D S     SSKR RTA+TS QL+ELE+EF  N YL R RR+E+A  LNL+E+Q+KIWFQN
Sbjct: 182 DKSPPGQASSKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQN 241

Query: 198 RRVKHKKEGKGSNHRGGGGGGAGGGGSAPQG 228
           RR+K+KK+ KG       GG +      P G
Sbjct: 242 RRMKYKKDQKGKGMLTSSGGQSPSRSPVPPG 272


>gi|84570137 homeobox B3 [Homo sapiens]
          Length = 431

 Score = 95.1 bits (235), Expect = 5e-20
 Identities = 57/128 (44%), Positives = 73/128 (57%), Gaps = 2/128 (1%)

Query: 138 DSSSNQLPSSKRMRTAFTSTQLLELEREFASNMYLSRLRRIEIATYLNLSEKQVKIWFQN 197
           D S     +SKR RTA+TS QL+ELE+EF  N YL R RR+E+A  LNLSE+Q+KIWFQN
Sbjct: 179 DKSPPGSAASKRARTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLSERQIKIWFQN 238

Query: 198 RRVKHKKEGKGSNHRGGGGGGAGGGGSAPQGCK-CASLSSAKCSEDDDELPMSPSSSGKD 256
           RR+K+KK+ K         GG    GS PQ  +  A   +A  S        SP + GK 
Sbjct: 239 RRMKYKKDQKAKG-LASSSGGPSPAGSPPQPMQSTAGFMNALHSMTPSYESPSPPAFGKA 297

Query: 257 DRDLTVTP 264
            ++    P
Sbjct: 298 HQNAYALP 305



 Score = 34.3 bits (77), Expect = 0.11
 Identities = 14/23 (60%), Positives = 15/23 (65%)

Query: 206 GKGSNHRGGGGGGAGGGGSAPQG 228
           G GS   GGGGGG GGG  +P G
Sbjct: 162 GGGSGGSGGGGGGGGGGDKSPPG 184



 Score = 32.3 bits (72), Expect = 0.44
 Identities = 16/44 (36%), Positives = 20/44 (45%), Gaps = 4/44 (9%)

Query: 189 KQVKIWF----QNRRVKHKKEGKGSNHRGGGGGGAGGGGSAPQG 228
           KQ+  W     Q  ++K+   G      GGGGGG GGG     G
Sbjct: 127 KQIFPWMKESRQTSKLKNNSPGTAEGCGGGGGGGGGGGSGGSGG 170


>gi|148613882 homeobox A4 [Homo sapiens]
          Length = 320

 Score = 94.7 bits (234), Expect = 7e-20
 Identities = 70/173 (40%), Positives = 88/173 (50%), Gaps = 20/173 (11%)

Query: 64  ASQLHGPPGPPALPLLKASFPPFGSQYCHAPLGRQHSAVSPGVAHGPAAAAAAAALYQTS 123
           AS +  P  PP  PL   + PP   + C A      +  +PGV  G +A A    L   S
Sbjct: 132 ASHVLQPQLPP--PLQPRAVPPAAPRRCEA------APATPGVPAGGSAPACPLLLADKS 183

Query: 124 YPL----------PDPRQFHCISVDSSSNQLPSSKRMRTAFTSTQLLELEREFASNMYLS 173
            PL          P  ++ H  +V+ S N     KR RTA+T  Q+LELE+EF  N YL+
Sbjct: 184 -PLGLKGKEPVVYPWMKKIHVSAVNPSYNG-GEPKRSRTAYTRQQVLELEKEFHFNRYLT 241

Query: 174 RLRRIEIATYLNLSEKQVKIWFQNRRVKHKKEGKGSNHRGGGGGGAGGGGSAP 226
           R RRIEIA  L LSE+QVKIWFQNRR+K KK+ K  N +      A      P
Sbjct: 242 RRRRIEIAHTLCLSERQVKIWFQNRRMKWKKDHKLPNTKMRSSNSASASAGPP 294


>gi|239748344 PREDICTED: NK1 homeobox 1 [Homo sapiens]
          Length = 653

 Score = 94.0 bits (232), Expect = 1e-19
 Identities = 67/165 (40%), Positives = 86/165 (52%), Gaps = 11/165 (6%)

Query: 71  PGPPALPLLKASFPPFGSQYCHAPLG-RQHSAVSPGVAHGPAAAAAAAALYQTSYPLPDP 129
           P  P+   L+ + PP        P G R++S V+PG   G AA   A    Q +     P
Sbjct: 24  PAQPSWARLRPTRPPEPPSTRQRPPGPRENSPVAPGPPGGAAAPGGAGTTPQGTATAAKP 83

Query: 130 RQFHCISVDSSSNQLPSSKRMRTAFTSTQLLELEREFASNMYLSRLRRIEIATYLNLSEK 189
           ++    S DS S +    +R RTAFT  QL+ LE +F +  YLS   R+ +A  L+L+E 
Sbjct: 84  KRKRTGS-DSKSGK---PRRARTAFTYEQLVALENKFKATRYLSVCERLNLALSLSLTET 139

Query: 190 QVKIWFQNRRVKHKKEGKG---SNHRGGGGG---GAGGGGSAPQG 228
           QVKIWFQNRR K KK+  G   S   GGGGG   GAG G   P G
Sbjct: 140 QVKIWFQNRRTKWKKQNPGADTSAPTGGGGGPGPGAGPGTGLPGG 184


>gi|239753784 PREDICTED: NK1 homeobox 1 [Homo sapiens]
          Length = 814

 Score = 91.3 bits (225), Expect = 8e-19
 Identities = 62/142 (43%), Positives = 78/142 (54%), Gaps = 10/142 (7%)

Query: 93  APLGRQHSAVSPGVAHGPAAAAAAAALYQTSYPLPDPRQFHCISVDSSSNQLPSSKRMRT 152
           AP  R++S V+PG   G AA   A    Q +     P++    S DS S +    +R RT
Sbjct: 612 APGPRENSPVAPGPPGGAAAPGGAGTTPQGTATAAKPKRKRTGS-DSKSGK---PRRART 667

Query: 153 AFTSTQLLELEREFASNMYLSRLRRIEIATYLNLSEKQVKIWFQNRRVKHKKEGKG---S 209
           AFT  QL+ LE +F +  YLS   R+ +A  L+L+E QVKIWFQNRR K KK+  G   S
Sbjct: 668 AFTYEQLVALENKFKATRYLSVCERLNLALSLSLTETQVKIWFQNRRTKWKKQNPGADTS 727

Query: 210 NHRGGGGG---GAGGGGSAPQG 228
              GGGGG   GAG G   P G
Sbjct: 728 APTGGGGGPGPGAGPGTGLPGG 749


>gi|4504469 homeobox B5 [Homo sapiens]
          Length = 269

 Score = 89.4 bits (220), Expect = 3e-18
 Identities = 56/108 (51%), Positives = 67/108 (62%), Gaps = 7/108 (6%)

Query: 103 SPGVAHG---PAAAAAAAALYQTSYPLPDPRQFHCISVDSSSNQLPSSKRMRTAFTSTQL 159
           SP +A     P A + AA   QT    P  R+ H IS D +    P  KR RTA+T  Q 
Sbjct: 151 SPSLARAQPEPMATSTAAPEGQTPQIFPWMRKLH-ISHDMTG---PDGKRARTAYTRYQT 206

Query: 160 LELEREFASNMYLSRLRRIEIATYLNLSEKQVKIWFQNRRVKHKKEGK 207
           LELE+EF  N YL+R RRIEIA  L LSE+Q+KIWFQNRR+K KK+ K
Sbjct: 207 LELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKKDNK 254


>gi|23397672 homeobox D4 [Homo sapiens]
          Length = 255

 Score = 89.0 bits (219), Expect = 4e-18
 Identities = 66/174 (37%), Positives = 82/174 (47%), Gaps = 31/174 (17%)

Query: 40  HGLSPGACHARKAGLLCVCPLCVTASQLHGPPGPPALPLLKASFPPFGSQYCHAPLGRQH 99
           HG  PG      A     CP          PP PP  PL               P  R +
Sbjct: 78  HGQEPGGPGGHYAAPGEPCP---------APPAPPPAPL---------------PGARAY 113

Query: 100 SAVSPGVAHGPAAAAAAAALYQTSYPLPDPRQFHCISVDSSSNQLPSSKRMRTAFTSTQL 159
           S   P          +  AL Q +   P  ++ H  SV+ +       KR RTA+T  Q+
Sbjct: 114 SQSDP------KQPPSGTALKQPAVVYPWMKKVHVNSVNPNYTG-GEPKRSRTAYTRQQV 166

Query: 160 LELEREFASNMYLSRLRRIEIATYLNLSEKQVKIWFQNRRVKHKKEGKGSNHRG 213
           LELE+EF  N YL+R RRIEIA  L LSE+Q+KIWFQNRR+K KK+ K  N +G
Sbjct: 167 LELEKEFHFNRYLTRRRRIEIAHTLCLSERQIKIWFQNRRMKWKKDHKLPNTKG 220


>gi|4504465 homeobox B2 [Homo sapiens]
          Length = 356

 Score = 88.6 bits (218), Expect = 5e-18
 Identities = 64/186 (34%), Positives = 91/186 (48%), Gaps = 29/186 (15%)

Query: 70  PPGPPALPLLKAS--FPPFGSQYCHAPLGRQHSAVSPGVAHGPAAAAAAAALYQTSYPLP 127
           PP PP LP    +  FP    +       +  ++ SP  +  PA+   + A       LP
Sbjct: 80  PPPPPPLPAAPPAPEFPWMKEKKSAKKPSQSATSPSPAASAVPASGVGSPA---DGLGLP 136

Query: 128 DPRQFHCISVDSSSNQLPSSKRMRTAFTSTQLLELEREFASNMYLSRLRRIEIATYLNLS 187
           +                  ++R+RTA+T+TQLLELE+EF  N YL R RR+EIA  L+L+
Sbjct: 137 EAGG-------------GGARRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLT 183

Query: 188 EKQVKIWFQNRRVKHKKEGKGSNHRGGGGGGAGGGGSAPQGCKCASLSSAKCSEDDDELP 247
           E+QVK+WFQNRR+KHK++   + HR    G     G+    C  A        E+    P
Sbjct: 184 ERQVKVWFQNRRMKHKRQ---TQHREPPDGEPACPGALEDICDPA--------EEPAASP 232

Query: 248 MSPSSS 253
             PS+S
Sbjct: 233 GGPSAS 238


>gi|239742243 PREDICTED: HPX-153 homeobox [Homo sapiens]
          Length = 411

 Score = 88.2 bits (217), Expect = 7e-18
 Identities = 61/142 (42%), Positives = 77/142 (54%), Gaps = 10/142 (7%)

Query: 93  APLGRQHSAVSPGVAHGPAAAAAAAALYQTSYPLPDPRQFHCISVDSSSNQLPSSKRMRT 152
           AP  R++S V+ G   G AA   A    Q +     P++    S DS S +    +R RT
Sbjct: 209 APGPRENSPVAQGPPGGAAAPGGAGTTPQGTATAAKPKRKRTGS-DSKSGK---PRRART 264

Query: 153 AFTSTQLLELEREFASNMYLSRLRRIEIATYLNLSEKQVKIWFQNRRVKHKKEGKG---S 209
           AFT  QL+ LE +F +  YLS   R+ +A  L+L+E QVKIWFQNRR K KK+  G   S
Sbjct: 265 AFTYEQLVALENKFKATRYLSVCERLNLALSLSLTETQVKIWFQNRRTKWKKQNPGADTS 324

Query: 210 NHRGGGGG---GAGGGGSAPQG 228
              GGGGG   GAG G   P G
Sbjct: 325 APTGGGGGPGPGAGPGTGLPGG 346


>gi|24497538 homeobox C4 [Homo sapiens]
          Length = 264

 Score = 86.7 bits (213), Expect = 2e-17
 Identities = 61/167 (36%), Positives = 85/167 (50%), Gaps = 9/167 (5%)

Query: 93  APLGRQHSAVSPG--VAHGPAAAAAAAALYQTSYPLPDPRQFHCISVDSSSNQLPSSKRM 150
           APL    ++ SP       PA    ++A  +     P  ++ H  +V+ + N     KR 
Sbjct: 101 APLSGASASPSPAPPACSQPAPDHPSSAASKQPIVYPWMKKIHVSTVNPNYNG-GEPKRS 159

Query: 151 RTAFTSTQLLELEREFASNMYLSRLRRIEIATYLNLSEKQVKIWFQNRRVKHKKEGKGSN 210
           RTA+T  Q+LELE+EF  N YL+R RRIEIA  L LSE+Q+KIWFQNRR+K KK+ +  N
Sbjct: 160 RTAYTRQQVLELEKEFHYNRYLTRRRRIEIAHSLCLSERQIKIWFQNRRMKWKKDHRLPN 219

Query: 211 HRGGGGGGAGGGGSAPQGCKCASLSSAKCSEDDDELPMSPSSSGKDD 257
            +      AG   S        S ++   SED  +    P     +D
Sbjct: 220 TKVRSAPPAGAAPST------LSAATPGTSEDHSQSATPPEQQRAED 260


>gi|24497540 homeobox C4 [Homo sapiens]
          Length = 264

 Score = 86.7 bits (213), Expect = 2e-17
 Identities = 61/167 (36%), Positives = 85/167 (50%), Gaps = 9/167 (5%)

Query: 93  APLGRQHSAVSPG--VAHGPAAAAAAAALYQTSYPLPDPRQFHCISVDSSSNQLPSSKRM 150
           APL    ++ SP       PA    ++A  +     P  ++ H  +V+ + N     KR 
Sbjct: 101 APLSGASASPSPAPPACSQPAPDHPSSAASKQPIVYPWMKKIHVSTVNPNYNG-GEPKRS 159

Query: 151 RTAFTSTQLLELEREFASNMYLSRLRRIEIATYLNLSEKQVKIWFQNRRVKHKKEGKGSN 210
           RTA+T  Q+LELE+EF  N YL+R RRIEIA  L LSE+Q+KIWFQNRR+K KK+ +  N
Sbjct: 160 RTAYTRQQVLELEKEFHYNRYLTRRRRIEIAHSLCLSERQIKIWFQNRRMKWKKDHRLPN 219

Query: 211 HRGGGGGGAGGGGSAPQGCKCASLSSAKCSEDDDELPMSPSSSGKDD 257
            +      AG   S        S ++   SED  +    P     +D
Sbjct: 220 TKVRSAPPAGAAPST------LSAATPGTSEDHSQSATPPEQQRAED 260


>gi|24497517 homeobox A5 [Homo sapiens]
          Length = 270

 Score = 85.5 bits (210), Expect = 4e-17
 Identities = 57/120 (47%), Positives = 70/120 (58%), Gaps = 16/120 (13%)

Query: 110 PAAAAAAAALYQTSYPLPDP----------RQFHCISVDSSSNQLPSSKRMRTAFTSTQL 159
           PA++  A+A    S P P P          R+ H IS D+     P  KR RTA+T  Q 
Sbjct: 154 PASSEQASA---QSEPSPAPPAQPQIYPWMRKLH-ISHDNIGG--PEGKRARTAYTRYQT 207

Query: 160 LELEREFASNMYLSRLRRIEIATYLNLSEKQVKIWFQNRRVKHKKEGKGSNHRGGGGGGA 219
           LELE+EF  N YL+R RRIEIA  L LSE+Q+KIWFQNRR+K KK+ K  +      GGA
Sbjct: 208 LELEKEFHFNRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKKDNKLKSMSMAAAGGA 267


>gi|11321638 homeobox C5 [Homo sapiens]
          Length = 222

 Score = 85.5 bits (210), Expect = 4e-17
 Identities = 67/187 (35%), Positives = 86/187 (45%), Gaps = 25/187 (13%)

Query: 25  PPPLFPYAVPPPHALHGLSPGA---CHARKAGLLCVCPLC-VTASQLHGPPGPPALPLLK 80
           PPP       P ++LHG+   A    H  +       P C   A+  H P    A PL  
Sbjct: 50  PPPA------PSNSLHGVDMAANPRAHPDR-------PACSAAAAPGHAPGRDEAAPLN- 95

Query: 81  ASFPPFGSQYCHAPLGRQHSAVSPGVAHGPAAAAAAAALYQTSYPLPDPRQFHCISVDSS 140
              P   SQ    P   + +  S  +    A     A L Q     P P Q +       
Sbjct: 96  ---PGMYSQKAARPALEERAKSSGEIKEEQAQTGQPAGLSQP----PAPPQIYPWMTKLH 148

Query: 141 SNQLPSSKRMRTAFTSTQLLELEREFASNMYLSRLRRIEIATYLNLSEKQVKIWFQNRRV 200
            +     KR RT++T  Q LELE+EF  N YL+R RRIEIA  L L+E+Q+KIWFQNRR+
Sbjct: 149 MSHETDGKRSRTSYTRYQTLELEKEFHFNRYLTRRRRIEIANNLCLNERQIKIWFQNRRM 208

Query: 201 KHKKEGK 207
           K KK+ K
Sbjct: 209 KWKKDSK 215


>gi|24497556 homeobox A7 [Homo sapiens]
          Length = 230

 Score = 84.7 bits (208), Expect = 7e-17
 Identities = 48/101 (47%), Positives = 59/101 (58%), Gaps = 4/101 (3%)

Query: 145 PSSKRMRTAFTSTQLLELEREFASNMYLSRLRRIEIATYLNLSEKQVKIWFQNRRVKHKK 204
           P  KR R  +T  Q LELE+EF  N YL+R RRIEIA  L L+E+Q+KIWFQNRR+K KK
Sbjct: 128 PDRKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRRMKWKK 187

Query: 205 EGKGSNHRGGGGGGAGGGGSAPQGCKCASLSSAKCSEDDDE 245
           E K      G    A   G+ P     A+   A   +DD+E
Sbjct: 188 EHKDE----GPTAAAAPEGAVPSAAATAAADKADEEDDDEE 224


>gi|24497544 homeobox C6 isoform 2 [Homo sapiens]
          Length = 153

 Score = 81.3 bits (199), Expect = 8e-16
 Identities = 41/72 (56%), Positives = 52/72 (72%)

Query: 148 KRMRTAFTSTQLLELEREFASNMYLSRLRRIEIATYLNLSEKQVKIWFQNRRVKHKKEGK 207
           +R R  ++  Q LELE+EF  N YL+R RRIEIA  L L+E+Q+KIWFQNRR+K KKE  
Sbjct: 60  RRGRQIYSRYQTLELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKESN 119

Query: 208 GSNHRGGGGGGA 219
            ++   GGGGGA
Sbjct: 120 LTSTLSGGGGGA 131


>gi|4758554 homeobox C6 isoform 1 [Homo sapiens]
          Length = 235

 Score = 81.3 bits (199), Expect = 8e-16
 Identities = 41/72 (56%), Positives = 52/72 (72%)

Query: 148 KRMRTAFTSTQLLELEREFASNMYLSRLRRIEIATYLNLSEKQVKIWFQNRRVKHKKEGK 207
           +R R  ++  Q LELE+EF  N YL+R RRIEIA  L L+E+Q+KIWFQNRR+K KKE  
Sbjct: 142 RRGRQIYSRYQTLELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKESN 201

Query: 208 GSNHRGGGGGGA 219
            ++   GGGGGA
Sbjct: 202 LTSTLSGGGGGA 213


>gi|226437602 NK1 homeobox 2 [Homo sapiens]
          Length = 310

 Score = 80.5 bits (197), Expect = 1e-15
 Identities = 43/94 (45%), Positives = 54/94 (57%), Gaps = 13/94 (13%)

Query: 148 KRMRTAFTSTQLLELEREFASNMYLSRLRRIEIATYLNLSEKQVKIWFQNRRVKHKKEGK 207
           +R RTAFT  QL+ LE +F +  YLS   R+ +A  L+L+E QVKIWFQNRR K KK+  
Sbjct: 164 RRARTAFTYEQLVALENKFRATRYLSVCERLNLALSLSLTETQVKIWFQNRRTKWKKQNP 223

Query: 208 GSN-------------HRGGGGGGAGGGGSAPQG 228
           G++               GGGGGG  GG   P G
Sbjct: 224 GADGAAQVGGGAPQPGAAGGGGGGGSGGSPGPPG 257


>gi|239755439 PREDICTED: NK1 homeobox 2 [Homo sapiens]
          Length = 332

 Score = 80.5 bits (197), Expect = 1e-15
 Identities = 43/94 (45%), Positives = 54/94 (57%), Gaps = 13/94 (13%)

Query: 148 KRMRTAFTSTQLLELEREFASNMYLSRLRRIEIATYLNLSEKQVKIWFQNRRVKHKKEGK 207
           +R RTAFT  QL+ LE +F +  YLS   R+ +A  L+L+E QVKIWFQNRR K KK+  
Sbjct: 186 RRARTAFTYEQLVALENKFRATRYLSVCERLNLALSLSLTETQVKIWFQNRRTKWKKQNP 245

Query: 208 GSN-------------HRGGGGGGAGGGGSAPQG 228
           G++               GGGGGG  GG   P G
Sbjct: 246 GADGAAQVGGGAPQPGAAGGGGGGGSGGSPGPPG 279


>gi|239749920 PREDICTED: NK1 homeobox 2 [Homo sapiens]
          Length = 332

 Score = 80.5 bits (197), Expect = 1e-15
 Identities = 43/94 (45%), Positives = 54/94 (57%), Gaps = 13/94 (13%)

Query: 148 KRMRTAFTSTQLLELEREFASNMYLSRLRRIEIATYLNLSEKQVKIWFQNRRVKHKKEGK 207
           +R RTAFT  QL+ LE +F +  YLS   R+ +A  L+L+E QVKIWFQNRR K KK+  
Sbjct: 186 RRARTAFTYEQLVALENKFRATRYLSVCERLNLALSLSLTETQVKIWFQNRRTKWKKQNP 245

Query: 208 GSN-------------HRGGGGGGAGGGGSAPQG 228
           G++               GGGGGG  GG   P G
Sbjct: 246 GADGAAQVGGGAPQPGAAGGGGGGGSGGSPGPPG 279


>gi|239744223 PREDICTED: NK1 homeobox 2 [Homo sapiens]
          Length = 332

 Score = 80.5 bits (197), Expect = 1e-15
 Identities = 43/94 (45%), Positives = 54/94 (57%), Gaps = 13/94 (13%)

Query: 148 KRMRTAFTSTQLLELEREFASNMYLSRLRRIEIATYLNLSEKQVKIWFQNRRVKHKKEGK 207
           +R RTAFT  QL+ LE +F +  YLS   R+ +A  L+L+E QVKIWFQNRR K KK+  
Sbjct: 186 RRARTAFTYEQLVALENKFRATRYLSVCERLNLALSLSLTETQVKIWFQNRRTKWKKQNP 245

Query: 208 GSN-------------HRGGGGGGAGGGGSAPQG 228
           G++               GGGGGG  GG   P G
Sbjct: 246 GADGAAQVGGGAPQPGAAGGGGGGGSGGSPGPPG 279


>gi|24497526 homeobox B1 [Homo sapiens]
          Length = 301

 Score = 80.5 bits (197), Expect = 1e-15
 Identities = 63/173 (36%), Positives = 77/173 (44%), Gaps = 27/173 (15%)

Query: 92  HAPLGRQHSAVSPGVAHGPAAAAAAAALYQTSYP----LPDPRQFHCISVDS-------- 139
           H P G + +A     +  PA A   +   +T  P     P  R F  + V          
Sbjct: 141 HPPYGNEQTA-----SFAPAYADLLSEDKETPCPSEPNTPTARTFDWMKVKRNPPKTAKV 195

Query: 140 SSNQLPSSKRMRTAFTSTQLLELEREFASNMYLSRLRRIEIATYLNLSEKQVKIWFQNRR 199
           S   L S   +RT FT+ QL ELE+EF  N YLSR RR+EIA  L L+E QVKIWFQNRR
Sbjct: 196 SEPGLGSPSGLRTNFTTRQLTELEKEFHFNKYLSRARRVEIAATLELNETQVKIWFQNRR 255

Query: 200 VKHKKEGKGSNHRGGGGGGAGGGGSAPQGCKCASLSSAKCSEDDDELPMSPSS 252
           +K KK  +            G    AP GC   +   A           SPSS
Sbjct: 256 MKQKKREREE----------GRVPPAPPGCPKEAAGDASDQSTCTSPEASPSS 298


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.133    0.411 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,976,181
Number of Sequences: 37866
Number of extensions: 851063
Number of successful extensions: 13527
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 479
Number of HSP's successfully gapped in prelim test: 274
Number of HSP's that attempted gapping in prelim test: 8245
Number of HSP's gapped (non-prelim): 4056
length of query: 264
length of database: 18,247,518
effective HSP length: 100
effective length of query: 164
effective length of database: 14,460,918
effective search space: 2371590552
effective search space used: 2371590552
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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