Search of human proteins with 31742496

Search of human proteins with 31742496

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|31742496 dihydrouridine synthase 4-like [Homo sapiens]
         (317 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|31742496 dihydrouridine synthase 4-like [Homo sapiens]             652   0.0  
gi|40807366 PP3111 protein [Homo sapiens]                             160   2e-39
gi|8923374 dihydrouridine synthase 2-like, SMM1 homolog [Homo sa...   119   3e-27
gi|239788462 dihydrouridine synthase 3-like isoform 1 [Homo sapi...    77   2e-14
gi|239788483 dihydrouridine synthase 3-like isoform 2 [Homo sapi...    77   2e-14
gi|119943098 dihydropyrimidine dehydrogenase isoform 1 [Homo sap...    33   0.33 

>gi|31742496 dihydrouridine synthase 4-like [Homo sapiens]
          Length = 317

 Score =  652 bits (1683), Expect = 0.0
 Identities = 317/317 (100%), Positives = 317/317 (100%)

Query: 1   MKSDCMQTTICQERKKDPIEMFHSGQLVKVCAPMVRYSKLAFRTLVRKYSCDLCYTPMIV 60
           MKSDCMQTTICQERKKDPIEMFHSGQLVKVCAPMVRYSKLAFRTLVRKYSCDLCYTPMIV
Sbjct: 1   MKSDCMQTTICQERKKDPIEMFHSGQLVKVCAPMVRYSKLAFRTLVRKYSCDLCYTPMIV 60

Query: 61  AADFVKSIKARDSEFTTNQGDCPLIVQFAANDARLLSDAARIVCPYANGIDINCGCPQRW 120
           AADFVKSIKARDSEFTTNQGDCPLIVQFAANDARLLSDAARIVCPYANGIDINCGCPQRW
Sbjct: 61  AADFVKSIKARDSEFTTNQGDCPLIVQFAANDARLLSDAARIVCPYANGIDINCGCPQRW 120

Query: 121 AMAEGYGACLINKPELVQDMVKQVRNQVETPGFSVSIKIRIHDDLKRTVDLCQKAEATGV 180
           AMAEGYGACLINKPELVQDMVKQVRNQVETPGFSVSIKIRIHDDLKRTVDLCQKAEATGV
Sbjct: 121 AMAEGYGACLINKPELVQDMVKQVRNQVETPGFSVSIKIRIHDDLKRTVDLCQKAEATGV 180

Query: 181 SWITVHGRTAEERHQPVHYDSIKIIKENMSIPVIANGDIRSLKEAENVWRITGTDGVMVA 240
           SWITVHGRTAEERHQPVHYDSIKIIKENMSIPVIANGDIRSLKEAENVWRITGTDGVMVA
Sbjct: 181 SWITVHGRTAEERHQPVHYDSIKIIKENMSIPVIANGDIRSLKEAENVWRITGTDGVMVA 240

Query: 241 RGLLANPAMFAGYEETPLKCIWDWVDIALELGTPYMCFHQHLMYMMEKITSRQEKRVFNA 300
           RGLLANPAMFAGYEETPLKCIWDWVDIALELGTPYMCFHQHLMYMMEKITSRQEKRVFNA
Sbjct: 241 RGLLANPAMFAGYEETPLKCIWDWVDIALELGTPYMCFHQHLMYMMEKITSRQEKRVFNA 300

Query: 301 LSSTSAIIDYLTDHYGI 317
           LSSTSAIIDYLTDHYGI
Sbjct: 301 LSSTSAIIDYLTDHYGI 317


>gi|40807366 PP3111 protein [Homo sapiens]
          Length = 473

 Score =  160 bits (404), Expect = 2e-39
 Identities = 97/258 (37%), Positives = 138/258 (53%), Gaps = 8/258 (3%)

Query: 30  VCAPMVRYSKLAFRTLVRKYSCDLCYTPMIVAADFVKSIKARDSEFTTN--QGDCPLIVQ 87
           V APMV  S+LA+R L R++   LCYTPM+ A  FV+    R           D PLIVQ
Sbjct: 20  VVAPMVDQSELAWRLLSRRHGAQLCYTPMLHAQVFVRDANYRKENLYCEVCPEDRPLIVQ 79

Query: 88  FAANDARLLSDAARIVCPYANGIDINCGCPQRWAMAEGYGACLINKPELVQDMVKQVRNQ 147
           F AND  +   AA +   Y + ID+N GCPQ  A    YGA L ++ +L+Q M+     +
Sbjct: 80  FCANDPEVFVQAALLAQDYCDAIDLNLGCPQMIAKRGHYGAFLQDEWDLLQRMILLAHEK 139

Query: 148 VETPGFSVSIKIRIHDDLKRTVDLCQKAEATGVSWITVHGRTAEERHQ---PVHYDSIKI 204
           +  P   V+ KIR+  ++ +TV   Q  E  G   +TVHGRT E++        ++ IK 
Sbjct: 140 LSVP---VTCKIRVFPEIDKTVRYAQMLEKAGCQLLTVHGRTKEQKGPLSGAASWEHIKA 196

Query: 205 IKENMSIPVIANGDIRSLKEAENVWRITGTDGVMVARGLLANPAMFAGYEETPLKCIWDW 264
           +++ ++IPV ANG+I+ L++ E   R TG  GVM A G L NPA+F G      +   ++
Sbjct: 197 VRKAVAIPVFANGNIQCLQDVERCLRDTGVQGVMSAEGNLHNPALFEGRSPAVWELAEEY 256

Query: 265 VDIALELGTPYMCFHQHL 282
           +DI  E   P      HL
Sbjct: 257 LDIVREHPCPLSYVRAHL 274


>gi|8923374 dihydrouridine synthase 2-like, SMM1 homolog [Homo
           sapiens]
          Length = 493

 Score =  119 bits (299), Expect = 3e-27
 Identities = 86/301 (28%), Positives = 142/301 (47%), Gaps = 24/301 (7%)

Query: 30  VCAPMVRYSKLAFRTLVRKYSCDLCYTPMIVAADFVKSIKARDSEFTTNQGDCP------ 83
           + APMVR   L  R L   Y  D+ Y   ++    ++  +  +   +T     P      
Sbjct: 15  ILAPMVRVGTLPMRLLALDYGADIVYCEELIDLKMIQCKRVVNEVLSTVDFVAPDDRVVF 74

Query: 84  ---------LIVQFAANDARLLSDAARIVCPYANGIDINCGCPQRWAMAEGYGACLINKP 134
                    ++ Q   +DA      AR+V     GID+N GCP++++   G GA L++ P
Sbjct: 75  RTCEREQNRVVFQMGTSDAERALAVARLVENDVAGIDVNMGCPKQYSTKGGMGAALLSDP 134

Query: 135 ELVQDMVKQVRNQVETPGFSVSIKIRIHDDLKRTVDLCQKAEATGVSWITVHGRTAEERH 194
           + ++ ++  +      P   V+ KIRI   L+ T+ L ++ E TG++ I VHGR  EER 
Sbjct: 135 DKIEKILSTLVKGTRRP---VTCKIRILPSLEDTLSLVKRIERTGIAAIAVHGRKREERP 191

Query: 195 Q-PVHYDSIKIIKENMSIPVIANG----DIRSLKEAENVWRITGTDGVMVARGLLANPAM 249
           Q PV  + IK I + +SIPVIANG     I+   + E+  + T    VMVAR  + NP++
Sbjct: 192 QHPVSCEVIKAIADTLSIPVIANGGSHDHIQQYSDIEDFRQATAASSVMVARAAMWNPSI 251

Query: 250 FAGYEETPLKCIWD-WVDIALELGTPYMCFHQHLMYMMEKITSRQEKRVFNALSSTSAII 308
           F      PL+ +   ++  A++    Y      L  M+ +     + R+ +A  S+  I 
Sbjct: 252 FLKEGLRPLEEVMQKYIRYAVQYDNHYTNTKYCLCQMLREQLESPQGRLLHAAQSSREIC 311

Query: 309 D 309
           +
Sbjct: 312 E 312


>gi|239788462 dihydrouridine synthase 3-like isoform 1 [Homo
           sapiens]
          Length = 650

 Score = 77.4 bits (189), Expect = 2e-14
 Identities = 55/228 (24%), Positives = 108/228 (47%), Gaps = 6/228 (2%)

Query: 32  APMVRYSKLAFRTLVRKYSCDLCYTPMIVAADFVKSIKARDSEFTTNQGDCPLIVQFAAN 91
           AP+     L FR + +++  D+    M V  + ++   +  +    +Q +    VQ    
Sbjct: 310 APLTTCGNLPFRRICKRFGADVTCGEMAVCTNLLQGQMSEWALLKRHQCEDIFGVQLEGA 369

Query: 92  DARLLSDAARIVCPYA--NGIDINCGCPQRWAMAEGYGACLINKPELVQDMVKQVRNQVE 149
               ++  A ++      + +DIN GCP      +G G  L+N+    Q +V+ +   ++
Sbjct: 370 FPDTMTKCAELLSRTVEVDFVDINVGCPIDLVYKKGGGCALMNRSTKFQQIVRGMNQVLD 429

Query: 150 TPGFSVSIKIRIHDDLKRTVDLCQKAEATGVSWITVHGRTAEERHQPV-HYDSI-KIIKE 207
            P  +V I+  + + +     L  +    GV+ +T+HGR+ E+R+  +  +  I + ++ 
Sbjct: 430 VP-LTVKIRTGVQERVNLAHRLLPELRDWGVALVTLHGRSREQRYTKLADWQYIEECVQA 488

Query: 208 NMSIPVIANGDIRSLKEAENVWRITGTDGVMVARGLLANPAMFAGYEE 255
              +P+  NGDI S ++A    + TG  G+M+ARG L  P +F   +E
Sbjct: 489 ASPMPLFGNGDILSFEDANRAMQ-TGVTGIMIARGALLKPWLFTEIKE 535


>gi|239788483 dihydrouridine synthase 3-like isoform 2 [Homo
           sapiens]
          Length = 408

 Score = 77.4 bits (189), Expect = 2e-14
 Identities = 55/228 (24%), Positives = 108/228 (47%), Gaps = 6/228 (2%)

Query: 32  APMVRYSKLAFRTLVRKYSCDLCYTPMIVAADFVKSIKARDSEFTTNQGDCPLIVQFAAN 91
           AP+     L FR + +++  D+    M V  + ++   +  +    +Q +    VQ    
Sbjct: 68  APLTTCGNLPFRRICKRFGADVTCGEMAVCTNLLQGQMSEWALLKRHQCEDIFGVQLEGA 127

Query: 92  DARLLSDAARIVCPYA--NGIDINCGCPQRWAMAEGYGACLINKPELVQDMVKQVRNQVE 149
               ++  A ++      + +DIN GCP      +G G  L+N+    Q +V+ +   ++
Sbjct: 128 FPDTMTKCAELLSRTVEVDFVDINVGCPIDLVYKKGGGCALMNRSTKFQQIVRGMNQVLD 187

Query: 150 TPGFSVSIKIRIHDDLKRTVDLCQKAEATGVSWITVHGRTAEERHQPV-HYDSI-KIIKE 207
            P  +V I+  + + +     L  +    GV+ +T+HGR+ E+R+  +  +  I + ++ 
Sbjct: 188 VP-LTVKIRTGVQERVNLAHRLLPELRDWGVALVTLHGRSREQRYTKLADWQYIEECVQA 246

Query: 208 NMSIPVIANGDIRSLKEAENVWRITGTDGVMVARGLLANPAMFAGYEE 255
              +P+  NGDI S ++A    + TG  G+M+ARG L  P +F   +E
Sbjct: 247 ASPMPLFGNGDILSFEDANRAMQ-TGVTGIMIARGALLKPWLFTEIKE 293


>gi|119943098 dihydropyrimidine dehydrogenase isoform 1 [Homo
           sapiens]
          Length = 1025

 Score = 33.1 bits (74), Expect = 0.33
 Identities = 30/125 (24%), Positives = 58/125 (46%), Gaps = 10/125 (8%)

Query: 61  AADFVKSIKARDSEFTTNQGDCPLIVQFAANDARLLSDAARIVCPYANGIDINCGCPQRW 120
           AA + +S+    ++F  N     ++  +  ND   L  A +     A+ +++N  CP   
Sbjct: 618 AAYWCQSVTELKADFPDNIVIASIMCSYNKNDWTEL--AKKSEDSGADALELNLSCPH-- 673

Query: 121 AMAE-GYGACLINKPELVQDMVKQVRNQVETPGFSVSIKIRIHDDLKRTVDLCQKAEATG 179
            M E G G      PELV+++ + VR  V+ P F+     ++  ++   V + + A+  G
Sbjct: 674 GMGERGMGLACGQDPELVRNICRWVRQAVQIPFFA-----KLTPNVTDIVSIARAAKEGG 728

Query: 180 VSWIT 184
            + +T
Sbjct: 729 ANGVT 733


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.323    0.135    0.421 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,408,692
Number of Sequences: 37866
Number of extensions: 458237
Number of successful extensions: 903
Number of sequences better than 10.0: 6
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 1
Number of HSP's that attempted gapping in prelim test: 888
Number of HSP's gapped (non-prelim): 6
length of query: 317
length of database: 18,247,518
effective HSP length: 102
effective length of query: 215
effective length of database: 14,385,186
effective search space: 3092814990
effective search space used: 3092814990
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.