Guide to the Human Genome
Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Search of human proteins with 239756987

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239756987 PREDICTED: hypothetical protein XP_002345138 [Homo
sapiens]
         (459 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239756987 PREDICTED: hypothetical protein XP_002345138 [Homo ...   928   0.0  
gi|239746003 PREDICTED: hypothetical protein XP_002344191 [Homo ...   840   0.0  
gi|239751502 PREDICTED: hypothetical protein XP_002347876 [Homo ...    91   3e-18
gi|163965366 nascent polypeptide-associated complex alpha subuni...    62   8e-10
gi|110832843 TBP-associated factor 4 [Homo sapiens]                    62   1e-09
gi|24586659 scavenger receptor class F, member 2 isoform 1 [Homo...    61   2e-09
gi|33598937 scavenger receptor class F, member 2 isoform 2 [Homo...    61   2e-09
gi|169160903 PREDICTED: hypothetical protein [Homo sapiens]            59   9e-09
gi|169211815 PREDICTED: keratin associated protein 4.6 [Homo sap...    57   3e-08
gi|169162152 PREDICTED: hypothetical protein [Homo sapiens]            57   3e-08
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    57   3e-08
gi|169161145 PREDICTED: hypothetical protein [Homo sapiens]            57   3e-08
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    57   5e-08
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    55   1e-07
gi|153946391 N-methyl-D-aspartate receptor subunit 2D precursor ...    55   2e-07
gi|40353727 synaptopodin isoform A [Homo sapiens]                      54   4e-07
gi|239754674 PREDICTED: hypothetical protein [Homo sapiens]            53   5e-07
gi|14602435 Williams Beuren syndrome chromosome region 14 isofor...    52   9e-07
gi|14602433 Williams Beuren syndrome chromosome region 14 isofor...    52   9e-07
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]        52   9e-07
gi|54860079 nadrin isoform 1 [Homo sapiens]                            52   1e-06
gi|122937496 WAS/WASL interacting protein family, member 3 [Homo...    52   1e-06
gi|110815800 WD repeat domain 32 [Homo sapiens]                        52   1e-06
gi|182507165 thymus expressed gene 3-like [Homo sapiens]               51   2e-06
gi|14589876 embryonal Fyn-associated substrate isoform 2 [Homo s...    50   3e-06
gi|5031681 embryonal Fyn-associated substrate isoform 1 [Homo sa...    50   3e-06
gi|189181724 proteoglycan 4 isoform D [Homo sapiens]                   50   4e-06
gi|189181722 proteoglycan 4 isoform C [Homo sapiens]                   50   4e-06
gi|189181720 proteoglycan 4 isoform B [Homo sapiens]                   50   4e-06
gi|67190163 proteoglycan 4 isoform A [Homo sapiens]                    50   4e-06

>gi|239756987 PREDICTED: hypothetical protein XP_002345138 [Homo
           sapiens]
          Length = 459

 Score =  928 bits (2398), Expect = 0.0
 Identities = 459/459 (100%), Positives = 459/459 (100%)

Query: 1   METFEKHKAVSIQSELSNISNCCLPLGSNAQFLLRRRGMSKCDKIMCNDMGTLEPTPLLR 60
           METFEKHKAVSIQSELSNISNCCLPLGSNAQFLLRRRGMSKCDKIMCNDMGTLEPTPLLR
Sbjct: 1   METFEKHKAVSIQSELSNISNCCLPLGSNAQFLLRRRGMSKCDKIMCNDMGTLEPTPLLR 60

Query: 61  RKAAQLQPGRGKSCGARRAALPLLRYPPEPGVFPFLVLWTPPFAPGRISPPAPQAFLAQR 120
           RKAAQLQPGRGKSCGARRAALPLLRYPPEPGVFPFLVLWTPPFAPGRISPPAPQAFLAQR
Sbjct: 61  RKAAQLQPGRGKSCGARRAALPLLRYPPEPGVFPFLVLWTPPFAPGRISPPAPQAFLAQR 120

Query: 121 SPARASPGGGFTSAEGKRKTRPAGRGGGRTRRVVAAPESAAAAPGRSPSPADPGSTSSAT 180
           SPARASPGGGFTSAEGKRKTRPAGRGGGRTRRVVAAPESAAAAPGRSPSPADPGSTSSAT
Sbjct: 121 SPARASPGGGFTSAEGKRKTRPAGRGGGRTRRVVAAPESAAAAPGRSPSPADPGSTSSAT 180

Query: 181 RVPRARRSSRRALQPRHAAPDAPGAPSRSTSQATPPPAPRFPASRRPGAPRLLSRTRQRE 240
           RVPRARRSSRRALQPRHAAPDAPGAPSRSTSQATPPPAPRFPASRRPGAPRLLSRTRQRE
Sbjct: 181 RVPRARRSSRRALQPRHAAPDAPGAPSRSTSQATPPPAPRFPASRRPGAPRLLSRTRQRE 240

Query: 241 LGGSAAPSVAFSGDVTLSLERGPASAKPPPQVLTAEPREDATPGEGRLPDFEKQPHSPRE 300
           LGGSAAPSVAFSGDVTLSLERGPASAKPPPQVLTAEPREDATPGEGRLPDFEKQPHSPRE
Sbjct: 241 LGGSAAPSVAFSGDVTLSLERGPASAKPPPQVLTAEPREDATPGEGRLPDFEKQPHSPRE 300

Query: 301 RLDPPPAPFGQMILILGFRVGRGGTGSWSWRRGAGSAELPGCSCAQLAQQLARAGKSTES 360
           RLDPPPAPFGQMILILGFRVGRGGTGSWSWRRGAGSAELPGCSCAQLAQQLARAGKSTES
Sbjct: 301 RLDPPPAPFGQMILILGFRVGRGGTGSWSWRRGAGSAELPGCSCAQLAQQLARAGKSTES 360

Query: 361 RNRLNGRRGGVEARGGGGGVARAERDDVLQGLGLRGTEDWCARRAPRTSSGVRRGAAPGF 420
           RNRLNGRRGGVEARGGGGGVARAERDDVLQGLGLRGTEDWCARRAPRTSSGVRRGAAPGF
Sbjct: 361 RNRLNGRRGGVEARGGGGGVARAERDDVLQGLGLRGTEDWCARRAPRTSSGVRRGAAPGF 420

Query: 421 RGSSNTARRRSIPVSLNRAQALCPPQSTSLLVPSLQVPV 459
           RGSSNTARRRSIPVSLNRAQALCPPQSTSLLVPSLQVPV
Sbjct: 421 RGSSNTARRRSIPVSLNRAQALCPPQSTSLLVPSLQVPV 459


>gi|239746003 PREDICTED: hypothetical protein XP_002344191 [Homo
           sapiens]
          Length = 459

 Score =  840 bits (2169), Expect = 0.0
 Identities = 415/415 (100%), Positives = 415/415 (100%)

Query: 45  IMCNDMGTLEPTPLLRRKAAQLQPGRGKSCGARRAALPLLRYPPEPGVFPFLVLWTPPFA 104
           IMCNDMGTLEPTPLLRRKAAQLQPGRGKSCGARRAALPLLRYPPEPGVFPFLVLWTPPFA
Sbjct: 45  IMCNDMGTLEPTPLLRRKAAQLQPGRGKSCGARRAALPLLRYPPEPGVFPFLVLWTPPFA 104

Query: 105 PGRISPPAPQAFLAQRSPARASPGGGFTSAEGKRKTRPAGRGGGRTRRVVAAPESAAAAP 164
           PGRISPPAPQAFLAQRSPARASPGGGFTSAEGKRKTRPAGRGGGRTRRVVAAPESAAAAP
Sbjct: 105 PGRISPPAPQAFLAQRSPARASPGGGFTSAEGKRKTRPAGRGGGRTRRVVAAPESAAAAP 164

Query: 165 GRSPSPADPGSTSSATRVPRARRSSRRALQPRHAAPDAPGAPSRSTSQATPPPAPRFPAS 224
           GRSPSPADPGSTSSATRVPRARRSSRRALQPRHAAPDAPGAPSRSTSQATPPPAPRFPAS
Sbjct: 165 GRSPSPADPGSTSSATRVPRARRSSRRALQPRHAAPDAPGAPSRSTSQATPPPAPRFPAS 224

Query: 225 RRPGAPRLLSRTRQRELGGSAAPSVAFSGDVTLSLERGPASAKPPPQVLTAEPREDATPG 284
           RRPGAPRLLSRTRQRELGGSAAPSVAFSGDVTLSLERGPASAKPPPQVLTAEPREDATPG
Sbjct: 225 RRPGAPRLLSRTRQRELGGSAAPSVAFSGDVTLSLERGPASAKPPPQVLTAEPREDATPG 284

Query: 285 EGRLPDFEKQPHSPRERLDPPPAPFGQMILILGFRVGRGGTGSWSWRRGAGSAELPGCSC 344
           EGRLPDFEKQPHSPRERLDPPPAPFGQMILILGFRVGRGGTGSWSWRRGAGSAELPGCSC
Sbjct: 285 EGRLPDFEKQPHSPRERLDPPPAPFGQMILILGFRVGRGGTGSWSWRRGAGSAELPGCSC 344

Query: 345 AQLAQQLARAGKSTESRNRLNGRRGGVEARGGGGGVARAERDDVLQGLGLRGTEDWCARR 404
           AQLAQQLARAGKSTESRNRLNGRRGGVEARGGGGGVARAERDDVLQGLGLRGTEDWCARR
Sbjct: 345 AQLAQQLARAGKSTESRNRLNGRRGGVEARGGGGGVARAERDDVLQGLGLRGTEDWCARR 404

Query: 405 APRTSSGVRRGAAPGFRGSSNTARRRSIPVSLNRAQALCPPQSTSLLVPSLQVPV 459
           APRTSSGVRRGAAPGFRGSSNTARRRSIPVSLNRAQALCPPQSTSLLVPSLQVPV
Sbjct: 405 APRTSSGVRRGAAPGFRGSSNTARRRSIPVSLNRAQALCPPQSTSLLVPSLQVPV 459


>gi|239751502 PREDICTED: hypothetical protein XP_002347876 [Homo
           sapiens]
          Length = 74

 Score = 90.5 bits (223), Expect = 3e-18
 Identities = 45/49 (91%), Positives = 45/49 (91%)

Query: 411 GVRRGAAPGFRGSSNTARRRSIPVSLNRAQALCPPQSTSLLVPSLQVPV 459
           G    AAPGFRGSSNTARRRSIPVSLNRAQALCPPQSTSLLVPSLQVPV
Sbjct: 26  GFAEAAAPGFRGSSNTARRRSIPVSLNRAQALCPPQSTSLLVPSLQVPV 74


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 62.4 bits (150), Expect = 8e-10
 Identities = 74/263 (28%), Positives = 102/263 (38%), Gaps = 24/263 (9%)

Query: 84   LRYPPEPGVFPFLVLWTPPFAPGRISPPAPQAFLAQRSPARASPGGGFTSAEGK------ 137
            L  PP  G  P     TPP   G ++ P P+      +    SP GG  +   K      
Sbjct: 1117 LATPPHKGA-PTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTP 1175

Query: 138  RKTRPAGRGGGRTRRVVAAPESAAAAPGRSPSPADPGSTSSATRVPRARRSSRRALQPRH 197
              T P+ +GG  T     AP + AA P   PSP    +T S    P    ++  + +   
Sbjct: 1176 AATPPSPKGGLATPSPKGAPTTPAATP---PSPKGGLATPSPKGAPTTPAATPPSPKGGL 1232

Query: 198  AAPDAPGAPSRSTSQATPPPAPRFPASRRP-GAPRLLSRTRQRELGGSAAPSVAFSGDVT 256
            A P   GAP  +T  ATPP     PA+  P GAP   + T     GG A P    + +  
Sbjct: 1233 ATPSPKGAP--TTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPA 1290

Query: 257  LSLERGPASAKPPPQVLTAEPREDATPGEGRLPDFEKQPHSPRERLDP------PPAPFG 310
            +     P S K  P   T+ P+   TP     P  +  P +P  +  P      PP+P G
Sbjct: 1291 VVT---PPSPKGGP--ATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKG 1345

Query: 311  QMILILGFRVGRGGTGSWSWRRG 333
               L       +GG  + S + G
Sbjct: 1346 TPTLPATTPSSKGGPTTPSSKEG 1368



 Score = 60.5 bits (145), Expect = 3e-09
 Identities = 65/216 (30%), Positives = 82/216 (37%), Gaps = 22/216 (10%)

Query: 88   PEPGVFPFLVLWTPPFAPGRISPPAPQAFLAQRSPARASPGGGFTSAEGK------RKTR 141
            P P   P     TPP   G ++ P+P+      +    SP GG  +   K        T 
Sbjct: 1189 PSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATP 1248

Query: 142  PAGRGGGRTRRVVAAPESAAAAP----GRSPSPADPGSTSSATRVPRARRSSRRALQPRH 197
            P+ +GG  T     AP   AA P    G   +P   G+ + A   P + +    A  P  
Sbjct: 1249 PSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGG-PATSPPK 1307

Query: 198  AAPDAPGA--PSRSTSQATPPP--APRFPASRRP---GAPRLLSRTRQRELGGSAAPSVA 250
             AP  P A  PS   S  TPPP  AP  PA   P   G P L + T   + GG   PS  
Sbjct: 1308 GAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSK-GGPTTPSSK 1366

Query: 251  FSGD---VTLSLERGPASAKPPPQVLTAEPREDATP 283
                    T S + GPA   P P+   A P     P
Sbjct: 1367 EGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDP 1402



 Score = 53.1 bits (126), Expect = 5e-07
 Identities = 58/230 (25%), Positives = 89/230 (38%), Gaps = 46/230 (20%)

Query: 106  GRISPPAPQAFLAQRSPARASPGGGFTSAEGKRK------TRPAGRGGGRTRRVV--AAP 157
            G ++PPA      +++PA ++P GG  +   K        T P+ +     ++V   ++P
Sbjct: 1431 GDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSP 1490

Query: 158  ESAAAAPGRSPSPADPGSTSSATRVPRARRSSRR----------------ALQPRHAA-P 200
            + A A P    +P  P    S+ +   A  SSRR                 L P+ A  P
Sbjct: 1491 KKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIP 1550

Query: 201  DAPGAPSRSTSQATPPP--APRFPASRRPGAPRLLSRTRQRELGGSAAPSVAFSGDVTLS 258
             A   PS   + A P P  AP  P+S+   +P  ++ +  +      APS          
Sbjct: 1551 PAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYK-----GAPS---------- 1595

Query: 259  LERGPASAKPPPQVLTAEPREDATPGEGRLPDFEKQPHSPRERLDPPPAP 308
                P     PP V +  P+E  TP     P  EK P +P  +  P   P
Sbjct: 1596 ----PKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPP 1641



 Score = 50.1 bits (118), Expect = 4e-06
 Identities = 75/264 (28%), Positives = 95/264 (35%), Gaps = 56/264 (21%)

Query: 60   RRKAAQLQPGRGKSCGARRAALPLLRYPPEPGVFPFLVL--WTPPFAPGRISPPAPQAFL 117
            + +A     G   S   + A  P    PP P   P      W P   P   +PP+P+   
Sbjct: 920  KARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAP--TPPAATPPSPKG-- 975

Query: 118  AQRSPARASPGGGFTSAEGKRKTRPAGRGGGRTRRVVAAPESAAAAPGRSPSPADPGSTS 177
                PA  SP G  T       T P+ +GG  T     AP   A  P   PSP     + 
Sbjct: 976  ---GPATPSPKGAPTPPAA---TPPSPKGGPATPSPKGAPTPPAVTP---PSPK---GSP 1023

Query: 178  SATRVPRARRSSRRALQPRHAAPDAP-GAPSRSTSQATPPP--APRFPASRRP------- 227
            +AT  P+       A  P  A P +P G+P+     ATP P  AP  PA+  P       
Sbjct: 1024 AATPFPKG------ASTPPAATPPSPKGSPA-----ATPLPKGAPTTPAATLPSPKGGPA 1072

Query: 228  -----GAPRLLSRTRQRELGGSAAPSVAFSGDVTLSLERGPASAKPPPQVLTAEPREDAT 282
                 GAP   + T     GG A PS              PA+  P P+   A P     
Sbjct: 1073 TPSLKGAPTPPAATPPSPKGGPATPS-------PKGAPMPPAATPPSPKGGLATP----- 1120

Query: 283  PGEGRLPDFEKQPHSPRERLDPPP 306
            P +G        P SP+  L  PP
Sbjct: 1121 PHKGAPTTPAATPPSPKGGLATPP 1144



 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 58/221 (26%), Positives = 86/221 (38%), Gaps = 31/221 (14%)

Query: 105  PGRISPPAPQAFLAQRSPARASPGGGFTSAEGKRKTRPAGRGGGRTRRVVAAPESAAAAP 164
            P  ++ P P+   A  +P +A P    TS+  K+             R   AP+   A+P
Sbjct: 888  PSVVNLPFPKEGPATPAPKQA-PALSMTSSSPKKA------------RATPAPKGIPASP 934

Query: 165  GRSPSPADPGSTSSATRVPRARRSSRRALQPRHAAPDAP-GAPSRSTSQATP------PP 217
                +P  P +T  + +   A  S + A  P  A P +P G P+  + +  P      PP
Sbjct: 935  SPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPP 994

Query: 218  APR-FPASRRP-GAPRLLSRTRQRELGGSAAPSVAFSGDVTLSLERGPASAKPPPQVLTA 275
            +P+  PA+  P GAP   + T     G  AA    F    +      P S K  P   T 
Sbjct: 995  SPKGGPATPSPKGAPTPPAVTPPSPKGSPAA--TPFPKGASTPPAATPPSPKGSP-AATP 1051

Query: 276  EPREDATPGEGRLPDFEKQPHSPRERLDP------PPAPFG 310
             P+   T     LP  +  P +P  +  P      PP+P G
Sbjct: 1052 LPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKG 1092


>gi|110832843 TBP-associated factor 4 [Homo sapiens]
          Length = 1085

 Score = 62.0 bits (149), Expect = 1e-09
 Identities = 78/269 (28%), Positives = 96/269 (35%), Gaps = 52/269 (19%)

Query: 54  EPTPLLRRKAAQLQPGRGKSCGARRAALPL--------LRYPPE-------PGVFPFLVL 98
           EP P  R +     P R      RR  +P         LR PPE       P      V 
Sbjct: 88  EPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVA 147

Query: 99  WTPPFAPGRISPPAPQAFLAQRSPARASPGGGFTSAEGKRKTRPAGRGGGRTRRVVAAPE 158
             P  AP   + PA  A LA R+     PG G     G  K  PAG G  +T    AA  
Sbjct: 148 AGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPGPGK--PAGPGAAQTLNGSAALL 205

Query: 159 SA--AAAPGRS------------PSPADPGSTSSATRVPRARRSSRRALQPRHAAPDAPG 204
           ++  AAAP  S            P PA PG+         A      A  P  AAP  P 
Sbjct: 206 NSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGA------AAPPAPAAPSPPA 259

Query: 205 APSRSTSQATPPPA-------------PRFPASRRPGAPRLLSRTRQRELGGSAAPSVAF 251
           AP+ +   A PPP              P  P +  P  P   +       G + AP+ A 
Sbjct: 260 APAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAA 319

Query: 252 SGDVTLSLERGP--ASAKPPPQVLTAEPR 278
            G   +S + GP  A+A P P V    P+
Sbjct: 320 GGPAGVSGQPGPGAAAAAPAPGVKAESPK 348



 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 61/214 (28%), Positives = 77/214 (35%), Gaps = 33/214 (15%)

Query: 121 SPARASPGGGFTSAEG----KRKTRPAGR----GGGRTRRVVAAPESAAAAPGRSP---- 168
           SPA A+  G    AEG      +  PAGR    GGG  R    +P       G +P    
Sbjct: 66  SPAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPAAK 125

Query: 169 -SPADPGSTSSATRVPRARRSSRRALQPRHAAPDAPGAPSRSTSQATPPPAPRFPASRRP 227
             P   GS  S   VP A  +     +P  A P  P  P+   ++A P P P       P
Sbjct: 126 LRPPPEGSAGSCAPVP-AAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGP 184

Query: 228 GAPRLLSRTRQRELGGS---------AAPSVAFSGDVTLSLERGPASAKP------PPQV 272
           G  +       + L GS         AAP+V+   +   +L   P  A P      PP V
Sbjct: 185 GPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFV 244

Query: 273 LTAEPREDATPGEGRLPDFEKQPHSPRERLDPPP 306
             A P   A P     P     P +P     PPP
Sbjct: 245 GAAAPPAPAAPS----PPAAPAPAAPAAAPPPPP 274



 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 51/197 (25%), Positives = 69/197 (35%), Gaps = 42/197 (21%)

Query: 79  AALPLLRYPPEPGVFPFLVLWTPPFAPGRISPPAPQAFLAQRSPARASPGGGFTSAEGKR 138
           A LPL    P+P   P  V+ TPPF  G  +PPAP A     +PA A+P           
Sbjct: 224 ALLPL----PKPAA-PGTVIQTPPFV-GAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAP 277

Query: 139 KTR-------------------PAGRGGGRTRRVVAAPESAAAAPGRSPSPADPGSTSSA 179
            T                    PA    G +     AP  AA  P        PG+ ++A
Sbjct: 278 ATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAA 337

Query: 180 TRVPRARRSSRRALQ--PRHAAPDAPGAPSRSTSQ---------------ATPPPAPRFP 222
                   S +R +Q  P  A   A   P+ + +                A PPPAP  P
Sbjct: 338 PAPGVKAESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVPPPAPGTP 397

Query: 223 ASRRPGAPRLLSRTRQR 239
                GA   ++++  R
Sbjct: 398 TGLPKGAAGAVTQSLSR 414



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 45/153 (29%), Positives = 52/153 (33%), Gaps = 21/153 (13%)

Query: 139 KTRPAGRGGGRTRRVVAAPESAAAAPGRSPSPADPGSTSSATRVPRARRSSRRALQPRHA 198
           + R A  G      V  +P  AA A   +P+   PG+        RAR        P   
Sbjct: 49  EVRAAAAGALGNHVVSGSPAGAAGAGPAAPAEGAPGAAPEPPPAGRAR--------PGGG 100

Query: 199 APDAPGAPSRSTSQATPPPAPRFPASRRPGAPRLLSRTRQRELGGSAAPSVAFSGDVTLS 258
            P  PG PS        P  P  PA   P A +L  R       GS AP V  +  V   
Sbjct: 101 GPQRPGPPS--------PRRPLVPAGPAPPAAKL--RPPPEGSAGSCAP-VPAAAAVAAG 149

Query: 259 LERGPASAKPP--PQVLTAEPREDATPGEGRLP 289
            E  PA    P  P  L A       PG G  P
Sbjct: 150 PEPAPAGPAKPAGPAALAARAGPGPGPGPGPGP 182



 Score = 33.5 bits (75), Expect = 0.41
 Identities = 58/212 (27%), Positives = 69/212 (32%), Gaps = 52/212 (24%)

Query: 51  GTLEPTPLLRRKAAQLQPGRGKSCGARRAALPLLRYPPEPGVFPFLVLWTP--PFAPGRI 108
           GT+  TP     AA   P       A   A P    PP P   P  +   P  P  P   
Sbjct: 235 GTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPA-PATLARPPGHPAGPPTA 293

Query: 109 SPPAPQAFLAQR------SPARASPGGGFTSAEGK-------RKTRPAGRGGGRTRRVVA 155
           +P  P    AQ       +PA A   GG     G+           P  +     R V A
Sbjct: 294 APAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQA 353

Query: 156 APESA----AAAP--------------GRSPSPAD-----PGS------------TSSAT 180
           AP +A    A+ P              G  PSPA      PG+            T S +
Sbjct: 354 APPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVPPPAPGTPTGLPKGAAGAVTQSLS 413

Query: 181 RVPRARRSSRRA-LQPRHAAPDAPGAPSRSTS 211
           R P A  S  RA L P   AP  P  P   T+
Sbjct: 414 RTPTATTSGIRATLTPTVLAPRLPQPPQNPTN 445


>gi|24586659 scavenger receptor class F, member 2 isoform 1 [Homo
           sapiens]
          Length = 870

 Score = 61.2 bits (147), Expect = 2e-09
 Identities = 78/273 (28%), Positives = 106/273 (38%), Gaps = 63/273 (23%)

Query: 88  PEPGVFPFLVLWTPPFAPGRISPPAPQAFLAQRSPARAS-PGGGFTSAEGKRKTRPA--- 143
           P P   P   L TP  A   I  P P +  ++RS +    PGG   +   +R+ RPA   
Sbjct: 588 PAPSPVP---LTTPASAEEAI--PLPASSDSERSASSVEGPGGALYARVARREARPARAR 642

Query: 144 GRGGGRT------RRVVAAPESA-------------AAAPGRSPSPADPGSTSSATRVPR 184
           G  GG +      RR    P+ A             AAA GR+PSP  PGS ++ +   R
Sbjct: 643 GEIGGLSLSPSPERRKPPPPDPATKPKVSWIHGKHSAAAAGRAPSPPPPGSEAAPSPSKR 702

Query: 185 ARRSSRRAL--------QPRHAAPDAPGAPSRSTSQATPPPAPRFPASRRPGAPRLL-SR 235
            R  S ++         + R   P  PG P  +T+ A P P    P +R   APR L + 
Sbjct: 703 KRTPSDKSAHTVEHGSPRTRDPTPRPPGLPEEATALAAPSP----PRARARAAPRPLGAH 758

Query: 236 TRQRELGGSAAPSVAFSGDV---TLSLER--------GPASAKPPPQVL---------TA 275
            R+R     A  +   + DV   T SL R        GP     PPQ             
Sbjct: 759 GRRRSPAKRAEAASMLAADVRGKTRSLGRAEVALGAQGPREKPAPPQKAKRSVPPASPAR 818

Query: 276 EPREDATPGEGRLPDFEKQPHSPRER--LDPPP 306
            P    TPG  +       P +PR++  +  PP
Sbjct: 819 APPATETPGPEKAATDLPAPETPRKKTPIQKPP 851



 Score = 55.5 bits (132), Expect = 1e-07
 Identities = 58/197 (29%), Positives = 78/197 (39%), Gaps = 25/197 (12%)

Query: 55  PTPLLRRKAAQLQPGRGKSCGARRAALPLLRYPPEPGVFPFLVLWTPPFAPGRISPPAPQ 114
           P+P  R++    +       G+ R   P  R P  P     L   +PP A  R +P    
Sbjct: 697 PSPSKRKRTPSDKSAHTVEHGSPRTRDPTPRPPGLPEEATALAAPSPPRARARAAPRPLG 756

Query: 115 AFLAQRSPARASPGGGFTSAEGKRKTRPAGRGGGRTRRVVAAPESAAAAPGRSPSPADPG 174
           A   +RSPA+ +      +A+ + KTR  GR            E A  A G    PA P 
Sbjct: 757 AHGRRRSPAKRAEAASMLAADVRGKTRSLGRA-----------EVALGAQGPREKPAPP- 804

Query: 175 STSSATRVPRARRSSRRALQPRHAAPDAPGAPSRSTSQATPPPAPRFPASRRP--GAPRL 232
                    +A+RS   A   R  AP A   P    + AT  PAP  P  + P    PR 
Sbjct: 805 --------QKAKRSVPPASPAR--APPATETPGPEKA-ATDLPAPETPRKKTPIQKPPRK 853

Query: 233 LSRTRQRELGGSAAPSV 249
            SR    ELG + AP++
Sbjct: 854 KSREAAGELGRAGAPTL 870



 Score = 33.9 bits (76), Expect = 0.32
 Identities = 40/158 (25%), Positives = 55/158 (34%), Gaps = 23/158 (14%)

Query: 153 VVAAPESAAAAPGRSPS-PADPGSTSSATRVPRARRSSRRALQPRHAAPDAPGAPSRSTS 211
           V   P   A A  R P  P  P    + + VP    +S     P  A+ D+     RS S
Sbjct: 563 VYCVPHEEAPAESRDPEVPTVPAEAPAPSPVPLTTPASAEEAIPLPASSDS----ERSAS 618

Query: 212 QATPPPAPRFP-ASRRPGAPRLLSRTRQRELGGSAAPSVAFSGDVTLSLERGPASAKPPP 270
               P    +   +RR   P   +R R  E+GG             LSL   P   KPPP
Sbjct: 619 SVEGPGGALYARVARREARP---ARARG-EIGG-------------LSLSPSPERRKPPP 661

Query: 271 QVLTAEPREDATPGEGRLPDFEKQPHSPRERLDPPPAP 308
                +P+     G+       + P  P    +  P+P
Sbjct: 662 PDPATKPKVSWIHGKHSAAAAGRAPSPPPPGSEAAPSP 699


>gi|33598937 scavenger receptor class F, member 2 isoform 2 [Homo
           sapiens]
          Length = 865

 Score = 61.2 bits (147), Expect = 2e-09
 Identities = 78/273 (28%), Positives = 106/273 (38%), Gaps = 63/273 (23%)

Query: 88  PEPGVFPFLVLWTPPFAPGRISPPAPQAFLAQRSPARAS-PGGGFTSAEGKRKTRPA--- 143
           P P   P   L TP  A   I  P P +  ++RS +    PGG   +   +R+ RPA   
Sbjct: 583 PAPSPVP---LTTPASAEEAI--PLPASSDSERSASSVEGPGGALYARVARREARPARAR 637

Query: 144 GRGGGRT------RRVVAAPESA-------------AAAPGRSPSPADPGSTSSATRVPR 184
           G  GG +      RR    P+ A             AAA GR+PSP  PGS ++ +   R
Sbjct: 638 GEIGGLSLSPSPERRKPPPPDPATKPKVSWIHGKHSAAAAGRAPSPPPPGSEAAPSPSKR 697

Query: 185 ARRSSRRAL--------QPRHAAPDAPGAPSRSTSQATPPPAPRFPASRRPGAPRLL-SR 235
            R  S ++         + R   P  PG P  +T+ A P P    P +R   APR L + 
Sbjct: 698 KRTPSDKSAHTVEHGSPRTRDPTPRPPGLPEEATALAAPSP----PRARARAAPRPLGAH 753

Query: 236 TRQRELGGSAAPSVAFSGDV---TLSLER--------GPASAKPPPQVL---------TA 275
            R+R     A  +   + DV   T SL R        GP     PPQ             
Sbjct: 754 GRRRSPAKRAEAASMLAADVRGKTRSLGRAEVALGAQGPREKPAPPQKAKRSVPPASPAR 813

Query: 276 EPREDATPGEGRLPDFEKQPHSPRER--LDPPP 306
            P    TPG  +       P +PR++  +  PP
Sbjct: 814 APPATETPGPEKAATDLPAPETPRKKTPIQKPP 846



 Score = 55.5 bits (132), Expect = 1e-07
 Identities = 58/197 (29%), Positives = 78/197 (39%), Gaps = 25/197 (12%)

Query: 55  PTPLLRRKAAQLQPGRGKSCGARRAALPLLRYPPEPGVFPFLVLWTPPFAPGRISPPAPQ 114
           P+P  R++    +       G+ R   P  R P  P     L   +PP A  R +P    
Sbjct: 692 PSPSKRKRTPSDKSAHTVEHGSPRTRDPTPRPPGLPEEATALAAPSPPRARARAAPRPLG 751

Query: 115 AFLAQRSPARASPGGGFTSAEGKRKTRPAGRGGGRTRRVVAAPESAAAAPGRSPSPADPG 174
           A   +RSPA+ +      +A+ + KTR  GR            E A  A G    PA P 
Sbjct: 752 AHGRRRSPAKRAEAASMLAADVRGKTRSLGRA-----------EVALGAQGPREKPAPP- 799

Query: 175 STSSATRVPRARRSSRRALQPRHAAPDAPGAPSRSTSQATPPPAPRFPASRRP--GAPRL 232
                    +A+RS   A   R  AP A   P    + AT  PAP  P  + P    PR 
Sbjct: 800 --------QKAKRSVPPASPAR--APPATETPGPEKA-ATDLPAPETPRKKTPIQKPPRK 848

Query: 233 LSRTRQRELGGSAAPSV 249
            SR    ELG + AP++
Sbjct: 849 KSREAAGELGRAGAPTL 865



 Score = 33.9 bits (76), Expect = 0.32
 Identities = 40/158 (25%), Positives = 55/158 (34%), Gaps = 23/158 (14%)

Query: 153 VVAAPESAAAAPGRSPS-PADPGSTSSATRVPRARRSSRRALQPRHAAPDAPGAPSRSTS 211
           V   P   A A  R P  P  P    + + VP    +S     P  A+ D+     RS S
Sbjct: 558 VYCVPHEEAPAESRDPEVPTVPAEAPAPSPVPLTTPASAEEAIPLPASSDS----ERSAS 613

Query: 212 QATPPPAPRFP-ASRRPGAPRLLSRTRQRELGGSAAPSVAFSGDVTLSLERGPASAKPPP 270
               P    +   +RR   P   +R R  E+GG             LSL   P   KPPP
Sbjct: 614 SVEGPGGALYARVARREARP---ARARG-EIGG-------------LSLSPSPERRKPPP 656

Query: 271 QVLTAEPREDATPGEGRLPDFEKQPHSPRERLDPPPAP 308
                +P+     G+       + P  P    +  P+P
Sbjct: 657 PDPATKPKVSWIHGKHSAAAAGRAPSPPPPGSEAAPSP 694


>gi|169160903 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 426

 Score = 58.9 bits (141), Expect = 9e-09
 Identities = 97/351 (27%), Positives = 126/351 (35%), Gaps = 62/351 (17%)

Query: 111 PAPQAFLAQRSPARASPGGGFTSAEGKRKTRPAGRGGGRTRRVVAAPES-AAAAPGRSPS 169
           P P     QR P RA    G   A G      A      +RR+   P +   A+PG  P+
Sbjct: 43  PPPILPAPQRPPTRAREWEGAAWAAGATGVGAALLALPGSRRLGRVPLTFREASPG--PA 100

Query: 170 PADPGSTSSATRVPRARRSSRRALQPRHAAPDAPGAPSRSTSQATPPPAPRFPASRRPGA 229
           P  P +  S  R P  R         R  AP + G    + ++A PP             
Sbjct: 101 PGAPRARGSCGREPGPR---------RRRAPSSAGKRPAAAARAAPP------------R 139

Query: 230 PRLLSRTRQRELGGSAAPSVAFS-------GDVTLSLERGPASAKPP--PQVLTAEPRED 280
            R L+R   R +G    PSV  S               R P    PP  P++ +A P   
Sbjct: 140 QRSLARCLPRSVGSCVRPSVGPSLPRRHCRRHCRCHCRRRPLPKPPPLQPRLGSASPPRL 199

Query: 281 ATPGEG-RLPDFEKQPHSPRERLDPPPAPFGQMILILGFRVGRGGTGSWSWRRGAGS--- 336
           A P  G R P     P   R R +  PA  G   L L   + RGG    + RR  G    
Sbjct: 200 AAPLAGSRAPSLSPFPRRCRRRAERSPAGHG---LPLPRSLSRGGEVVGARRRRGGEERR 256

Query: 337 --AELPGCSCAQ--LAQQLARAGKSTESRNRLNGRRGGVEARGGGGGVARAERDDVLQGL 392
                 GC+     +    A  G++ E R     R+     RGGG GV+  E     QG 
Sbjct: 257 VRGRRQGCALGSPPIPAGPAAPGRAGERRAARQWRK-----RGGGPGVSPREG---AQGE 308

Query: 393 GLRG-------TEDWCARRAPRTSSG---VRRGAAPGFRGSSNTARRRSIP 433
           G+RG           C R +P T  G    R   A G R S+ +A    +P
Sbjct: 309 GVRGGVTPRARGSSTCLRPSPATWQGGAPYRAIFAAGPRLSAPSAEAEEVP 359



 Score = 30.8 bits (68), Expect = 2.7
 Identities = 36/126 (28%), Positives = 44/126 (34%), Gaps = 12/126 (9%)

Query: 183 PRARRSSRRALQPRHAAPDAPGAPSRSTSQATPPPAPRFPASRRPGAPRLLSRTRQRELG 242
           PR        + P+    DAPG    S +   PPP    PA +RP        TR RE  
Sbjct: 11  PRTPAPGCPEVAPQPEGTDAPGPAVCSPTARAPPPI--LPAPQRP-------PTRAREWE 61

Query: 243 GSA-APSVAFSGDVTLSLERGPASAKPPPQVLTAEPREDATPGEGRLPDFEKQPHSPRER 301
           G+A A      G   L+L       + P     A P     PG  R      +   PR R
Sbjct: 62  GAAWAAGATGVGAALLALPGSRRLGRVPLTFREASP--GPAPGAPRARGSCGREPGPRRR 119

Query: 302 LDPPPA 307
             P  A
Sbjct: 120 RAPSSA 125


>gi|169211815 PREDICTED: keratin associated protein 4.6 [Homo
           sapiens]
          Length = 288

 Score = 57.4 bits (137), Expect = 3e-08
 Identities = 71/250 (28%), Positives = 87/250 (34%), Gaps = 50/250 (20%)

Query: 70  RGKSCGARRAALPLLRYPPE---PGVFPFLVLWTPPFAPGRISPPAPQAFLAQRSPARAS 126
           RG SCG  R   PL  +      P      V W P  AP  + PPA         P  A+
Sbjct: 64  RGDSCGNTRNLYPLTPWSAPVVVPSALTRAVAWRPAAAPAAVRPPAA-------GPPAAA 116

Query: 127 PGGGFTSAEGKRKTRPAGRGGGRTRRVVAAPESAAAAPGRSPSPADPGSTSSATRVPRA- 185
           P              PA           AA  SAA+    SP  A P +  +A R P A 
Sbjct: 117 PAA----------VCPA-----------AADPSAASLCAASPPAAVPAAVPAAVRPPAAG 155

Query: 186 -RRSSRRALQPRHAAPDAPGAPSRSTSQATP---PPAPRFPASRRPGAPRLLSRTRQREL 241
              ++  A+ P  A P A    + S   A P    PA   PA+  PGA            
Sbjct: 156 PPAAALAAVYPAAADPSAASLCAASPLAAVPAAASPAAVAPAAVCPGA-----------A 204

Query: 242 GGSAAPSVAFSGDVTLSLERGPASAKPPPQVLTAEPREDATPGEGRLPDFEKQPHSPRER 301
           G SAA   A S    +     PA+A P      A  R  A P    +    + P +P   
Sbjct: 205 GPSAASLCAASQPAAVPAAASPAAAAPLAVNPAAAARAAAAPAAACVQSVAESPATPLAI 264

Query: 302 LDP---PPAP 308
             P   PPAP
Sbjct: 265 AQPVSFPPAP 274


>gi|169162152 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 520

 Score = 57.0 bits (136), Expect = 3e-08
 Identities = 116/402 (28%), Positives = 148/402 (36%), Gaps = 109/402 (27%)

Query: 49  DMGTLEPTPLL----RRKAAQLQPGRGKSCGA---RRAALPLLRYPPEPGVFPFLVLWTP 101
           + G  +P+P +    R K  Q + GRG        R AA   L  P EP         TP
Sbjct: 106 ERGRSKPSPPVSGTRRGKTGQWKEGRGSHPTPEPQRLAARRWLHSPREP---------TP 156

Query: 102 PFAPGRISPPA-----PQAFLAQRSPARASPGGGFTSAEGKRKTRPAGRGGGRTRRVVAA 156
           P   GR+S P      PQ+F   R P+                  P GRG GR  R    
Sbjct: 157 P---GRLSAPPRHGPHPQSF---RRPS----------------AHPPGRGSGRVPR--GQ 192

Query: 157 PESAAAAPGRSPSPADPGSTSSATRVPRARRSSRRALQPRHAAPDAPGAPSRSTSQATPP 216
           PE  A     S   A  GS +S     +  R+ R A + R  A  A G+  R  ++    
Sbjct: 193 PEQQAWEQRSSHFLAPEGSVASLLPSAKPARAPRPAPRAREEA--AAGSRGRGGAER--- 247

Query: 217 PAPRFPASRRPGAPRLLSRTRQRELGGSAAPSVAFSGDVTLSLERGPASAKPP--PQVLT 274
           PA R  A + P A  LL+          +A S+A       SL R P    PP  P++ +
Sbjct: 248 PAARGSAQQPPLARLLLA----------SAVSLA------ASLARSP----PPLQPRLGS 287

Query: 275 AEPREDATPGEG-RLPDFEKQPHSPRERLDPPPAPFGQMILILGFRVGRGGTGSWSWRRG 333
           A P   A P  G R P     P   R R +  PA  G   L L   + RGG    + RR 
Sbjct: 288 ASPPRLAAPLAGSRAPSLSPFPRRCRRRAERSPAGHG---LPLPRSLSRGGEVVGARRRR 344

Query: 334 AGS-----AELPGCSCAQ--LAQQLARAGKSTESRNRLNGRRGGVEARGGGGGVARAERD 386
            G          GC+     +    A  G++ E R     R+     RGGG GV+  E  
Sbjct: 345 GGEERRVRGRRQGCALGSPPIPAGPAAPGRAGERRAARQWRK-----RGGGPGVSPRE-- 397

Query: 387 DVLQGLGLRGTEDWCARRAPRTSSGVRRGAAPGFRGSSNTAR 428
                 G +G              GVR G  P  RGSS   R
Sbjct: 398 ------GAQG-------------EGVRGGVTPRARGSSTCLR 420



 Score = 36.2 bits (82), Expect = 0.064
 Identities = 62/233 (26%), Positives = 74/233 (31%), Gaps = 23/233 (9%)

Query: 59  LRRKAAQLQPGRGKSCGARRAALPLLRYPPEPGVFPFLVLWTPPFAPGRISPPAPQAFL- 117
           L R    LQP  G +   R AA       P    FP         +P     P P++   
Sbjct: 274 LARSPPPLQPRLGSASPPRLAAPLAGSRAPSLSPFPRRCRRRAERSPAGHGLPLPRSLSR 333

Query: 118 -AQRSPARASPGGGFTSAEGKRK----------TRPAGRGGGRTRRVVAAPESAAAAPGR 166
             +   AR   GG      G+R+            PA  G    RR           PG 
Sbjct: 334 GGEVVGARRRRGGEERRVRGRRQGCALGSPPIPAGPAAPGRAGERRAARQWRKRGGGPGV 393

Query: 167 SPSPADPGSTSSATRVPRARRSSRRALQPRHAAPDAPGAPSRSTSQATPP-PAPRFPASR 225
           SP     G        PRAR SS   L+P  A     GAP R+   A P   AP   A  
Sbjct: 394 SPREGAQGEGVRGGVTPRARGSS-TCLRPSPATWQG-GAPYRAIFAAGPRLSAPSAEAEE 451

Query: 226 RPGA--------PRLLSRTRQRELGGSAAPSVAFSGDVTLSLERGPASAKPPP 270
            PG           L SR  +    G  +PS   +    L  E G  S    P
Sbjct: 452 VPGGHTASNPTYEPLSSRRTKAPSEGRDSPSSPATSTHYLDRESGLGSVNSHP 504


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 57.0 bits (136), Expect = 3e-08
 Identities = 72/241 (29%), Positives = 91/241 (37%), Gaps = 42/241 (17%)

Query: 101 PPFAPGRISPPAPQAFLAQRSPARASPGGGFTS---AEGKRKTRPAGRGGGRTR------ 151
           P   P R S P       +  PA+ +  G  +S   A G  +  P G+ G R        
Sbjct: 75  PRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVA 134

Query: 152 --RVVAAPESAAAAPG--RSPSPADPGSTSSATRVPRARRSSRRALQPRHAAPDAPGAP- 206
             +   AP+ +A + G  R  S   PG+ S A    R+R +      PR A    P  P 
Sbjct: 135 RGKATEAPKRSALSAGARRDTSGPTPGTPSPAM-ARRSRAAGTEVGLPRPAPSARPRPPT 193

Query: 207 -------SRSTSQATPPPAPRFPASRRPGAPRLLSRTRQRELGGSAAP--SVAFSGDVTL 257
                  S ++  +T  P+P   A RRP A   L R   R L  SA P  S A SG    
Sbjct: 194 EGPRKSVSSASEHSTTEPSPA--ARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSAR 251

Query: 258 SLERGPA----------SAKPPPQVLTAEPREDATPGEGRLPDFEKQPHSPRERLDPPPA 307
              R PA           A  PPQV    PR+DA P  G L        SP      PP+
Sbjct: 252 GTPRAPAHPSQPKPKGLQALRPPQV--TPPRKDAAPALGPLSSSPLATPSP----SAPPS 305

Query: 308 P 308
           P
Sbjct: 306 P 306



 Score = 49.3 bits (116), Expect = 7e-06
 Identities = 97/376 (25%), Positives = 120/376 (31%), Gaps = 76/376 (20%)

Query: 57  PLLRRKAAQLQPGRGKSCGARRAALPLLRYPPEPGVFPFLVLWTPPFAPGRISPPAPQAF 116
           P L     Q+ P    S     +A P  + PP     P  +   PP AP  ++ P  QA 
Sbjct: 433 PSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQAL 492

Query: 117 LAQRSPARASPGGGFTSAEGKRKTRPAGRGGGRTRRVVAAP----------ESAAAAPGR 166
               SP  + PG    S        P      +   V+AAP               AP R
Sbjct: 493 ---PSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRR 549

Query: 167 SPSPADPGSTSSATRVPRARRSSRRALQPRHAAPDAPGAPSRSTSQATPPPAPRFPASRR 226
            P+P  P ++ S  R+  A             AP  P  PSRS S     P     +S  
Sbjct: 550 PPTPG-PDTSVSGPRLTLA------------LAPGPPPPPSRSPSSTLSGPDLAGHSSSA 596

Query: 227 PGAPRLLSRTRQRELGGSA---------------------APSVAFSGDVTLSL----ER 261
              P  L        GG+A                     AP +AF G     L      
Sbjct: 597 TSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPAT 656

Query: 262 GPASAKPPPQVLTAEPREDATPGEGRLPDFEKQPHSPRERLDPPPAPFGQMILILGFRVG 321
           GP SA     +   E  E ATP  G               LDP P+P        G +  
Sbjct: 657 GPGSADGLCTIYETEGPESATPAPG--------------ALDPGPSPGTS-----GGKAA 697

Query: 322 RGGTGSWSWR--RGAGSAELP-GCSCAQLAQQ-LARAGKSTESRNRLNGRRGGVEARGGG 377
            G     S R  + A   ELP G   A + Q  L+R      +     G  GG     GG
Sbjct: 698 AGAGAGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAAAEGAAGGSGGGPGGAEGG 757

Query: 378 G--GVARAERDDVLQG 391
           G  G ARA   D   G
Sbjct: 758 GVTGGARAALSDAELG 773



 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 61/267 (22%), Positives = 83/267 (31%), Gaps = 30/267 (11%)

Query: 48  NDMGTLEPTPLLRRKAA-----QLQPGRGKSCGARRAALPLLRYPPEPGVFPFLVLWTPP 102
           ++  T EP+P  RR+ +     Q    R  S  A   + P    P   G          P
Sbjct: 204 SEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGT---------P 254

Query: 103 FAPGRISPPAPQAFLAQRSPARASPGGGFTSAEGKRKTRPAGRGGGRTRRVVAAPESAAA 162
            AP   S P P+   A R P    P      A G   + P            +AP S   
Sbjct: 255 RAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQT 314

Query: 163 APGRSPSPADPGSTSSATRVPRARRSSRRALQPRHAAPDAPGAPSRSTSQATPPPAPRFP 222
            P    +P    +TS  +            LQ  H+   +P     +T     PPA   P
Sbjct: 315 LPSPPATPPSQATTSLGS----------PTLQATHSFLPSPPLSPLATPPPQAPPALALP 364

Query: 223 ASRRPGAPRLLSRTRQRELGGSAAPSVAFSGDVTLSLERGPASAKP-PPQVLTAEPREDA 281
             + P +P          L   A PS      + + L + P S  P PP      P    
Sbjct: 365 PLQAPPSP-----PASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASP 419

Query: 282 TPGEGRLPDFEKQPHSPRERLDPPPAP 308
                  P  +  P      L  PP+P
Sbjct: 420 PVSPSATPPSQAPPSLAAPPLQVPPSP 446



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 73/264 (27%), Positives = 85/264 (32%), Gaps = 84/264 (31%)

Query: 80  ALPLLRYPPEPGVFPFLVLWTPPFAP-GRISPPAPQAFLAQRSPARASPGGGFTSAEGKR 138
           ALP L+ PP P         +PP +P    SP AP A       A  SP           
Sbjct: 362 ALPPLQAPPSPPA-------SPPLSPLATPSPQAPNALAVHLLQAPFSPPPS-------- 406

Query: 139 KTRPAGRGGGRTRRVVAAPESAAAAPGRSPSPADPGSTSSATRVPRARRSSRRALQPRHA 198
                          V AP S  A+P  SPS   P     +   P           P   
Sbjct: 407 -------------PPVQAPFSPPASPPVSPSATPPSQAPPSLAAP-----------PLQV 442

Query: 199 APDAPGAPSRSTSQATPPPAPRFP--------ASRRPGAPRLLSRTRQRELGGSAAPSVA 250
            P  P +P  S S ATPPP    P        A   P AP  L+    + L    +P  +
Sbjct: 443 PPSPPASPPMSPS-ATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQAL---PSPPAS 498

Query: 251 FSGDV----TLSLERGPASAKPP--PQVLTA----------------EPREDATPGEGRL 288
           F G      + SL   P +  PP  P VL A                 PR   TPG    
Sbjct: 499 FPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPG---- 554

Query: 289 PDFEKQPHSPRERL----DPPPAP 308
           PD       PR  L     PPP P
Sbjct: 555 PD--TSVSGPRLTLALAPGPPPPP 576



 Score = 32.0 bits (71), Expect = 1.2
 Identities = 45/197 (22%), Positives = 68/197 (34%), Gaps = 23/197 (11%)

Query: 104 APGRISPPAPQAFLAQRSPARASPGGGFTSAEGKRKTRPAGRGGGRTRRVVAAPESAAAA 163
           APG ++P  P +    R P   +P             R  G  G   R+ +A  E A   
Sbjct: 21  APGLLTPRPPGS---PRPPPPVTPAA----------LRVLGAAGAVGRKPLA--ERAGGI 65

Query: 164 PGRSPSPADPGSTSSATRVPRARRSSRRALQPRHAAPDAPGAPSRSTSQATPPPAPRFPA 223
            G +   + P +  + T  P A     RA   ++ +P    +P R++   T  P P    
Sbjct: 66  GGATIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRAS--GTTRPGPLGQK 123

Query: 224 SRRPGAPRLLSRTRQRELGGSAAPSVAFSGDVTLSLERGPASAKPPPQVLTAEPREDATP 283
             R  A   ++R +  E    +A S     D +     GP    P P +           
Sbjct: 124 GLRISAEETVARGKATEAPKRSALSAGARRDTS-----GPTPGTPSPAMARRSRAAGTEV 178

Query: 284 GEGRLPDFEKQPHSPRE 300
           G  R P    +P  P E
Sbjct: 179 GLPR-PAPSARPRPPTE 194



 Score = 30.0 bits (66), Expect = 4.6
 Identities = 68/287 (23%), Positives = 88/287 (30%), Gaps = 57/287 (19%)

Query: 198 AAPDAPGAPSRSTSQATPPPAPRFPASRRPGAPRLLSRT----------RQRELGGSAAP 247
           AA   P A +       PP +PR P    P A R+L             R   +GG+  P
Sbjct: 12  AAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIP 71

Query: 248 SVAFSGDVTLSLERGPASAKPPPQVLTAEPREDATPGEGRLPDFEKQPHSPRERLDPPPA 307
             A     T +  R PAS +       A P ++ +PG    P         R      P 
Sbjct: 72  ESAPRAGPTRT-SRPPASGRGE----RAPPAKNTSPGPVSSPG--------RASGTTRPG 118

Query: 308 PFGQMILILGFR--VGRGGTGSWSWR-------RGAGSAELPGCSCAQLAQQLARAGKST 358
           P GQ  L +     V RG       R       R   S   PG     +A++   AG   
Sbjct: 119 PLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEV 178

Query: 359 ESRNRLNGRRGGVEARGGGGGVARAERDDVLQGLGLRGTEDWCARRAPRTSSGVRRGAA- 417
                    R      G    V+ A      +           ARR P    G++R A+ 
Sbjct: 179 GLPRPAPSARPRPPTEGPRKSVSSASEHSTTE-------PSPAARRRPSAGGGLQRPASR 231

Query: 418 ----------------PGFRGSSNTARRRSIPVSLNRAQALCPPQST 448
                           P  RG+       S P      QAL PPQ T
Sbjct: 232 SLSSSATPLSSPARSGPSARGTPRAPAHPSQP-KPKGLQALRPPQVT 277


>gi|169161145 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 520

 Score = 57.0 bits (136), Expect = 3e-08
 Identities = 116/402 (28%), Positives = 148/402 (36%), Gaps = 109/402 (27%)

Query: 49  DMGTLEPTPLL----RRKAAQLQPGRGKSCGA---RRAALPLLRYPPEPGVFPFLVLWTP 101
           + G  +P+P +    R K  Q + GRG        R AA   L  P EP         TP
Sbjct: 106 ERGRSKPSPPVSGTRRGKTGQWKEGRGSHPTPEPQRLAARRWLHSPREP---------TP 156

Query: 102 PFAPGRISPPA-----PQAFLAQRSPARASPGGGFTSAEGKRKTRPAGRGGGRTRRVVAA 156
           P   GR+S P      PQ+F   R P+                  P GRG GR  R    
Sbjct: 157 P---GRLSAPPRHGPHPQSF---RRPS----------------AHPPGRGSGRVPR--GQ 192

Query: 157 PESAAAAPGRSPSPADPGSTSSATRVPRARRSSRRALQPRHAAPDAPGAPSRSTSQATPP 216
           PE  A     S   A  GS +S     +  R+ R A + R  A  A G+  R  ++    
Sbjct: 193 PEQQAWEQRSSHFLAPEGSVASLLPSAKPARAPRPAPRAREEA--AAGSRGRGGAER--- 247

Query: 217 PAPRFPASRRPGAPRLLSRTRQRELGGSAAPSVAFSGDVTLSLERGPASAKPP--PQVLT 274
           PA R  A + P A  LL+          +A S+A       SL R P    PP  P++ +
Sbjct: 248 PAARGSAQQPPLARLLLA----------SAVSLA------ASLARSP----PPLQPRLGS 287

Query: 275 AEPREDATPGEG-RLPDFEKQPHSPRERLDPPPAPFGQMILILGFRVGRGGTGSWSWRRG 333
           A P   A P  G R P     P   R R +  PA  G   L L   + RGG    + RR 
Sbjct: 288 ASPPRLAAPLAGSRAPSLSPFPRRCRRRAERSPAGHG---LPLPRSLSRGGEVVGARRRR 344

Query: 334 AGS-----AELPGCSCAQ--LAQQLARAGKSTESRNRLNGRRGGVEARGGGGGVARAERD 386
            G          GC+     +    A  G++ E R     R+     RGGG GV+  E  
Sbjct: 345 GGEERRVRGRRQGCALGSPPIPAGPAAPGRAGERRAARQWRK-----RGGGPGVSPRE-- 397

Query: 387 DVLQGLGLRGTEDWCARRAPRTSSGVRRGAAPGFRGSSNTAR 428
                 G +G              GVR G  P  RGSS   R
Sbjct: 398 ------GAQG-------------EGVRGGVTPRARGSSTCLR 420



 Score = 36.2 bits (82), Expect = 0.064
 Identities = 62/233 (26%), Positives = 74/233 (31%), Gaps = 23/233 (9%)

Query: 59  LRRKAAQLQPGRGKSCGARRAALPLLRYPPEPGVFPFLVLWTPPFAPGRISPPAPQAFL- 117
           L R    LQP  G +   R AA       P    FP         +P     P P++   
Sbjct: 274 LARSPPPLQPRLGSASPPRLAAPLAGSRAPSLSPFPRRCRRRAERSPAGHGLPLPRSLSR 333

Query: 118 -AQRSPARASPGGGFTSAEGKRK----------TRPAGRGGGRTRRVVAAPESAAAAPGR 166
             +   AR   GG      G+R+            PA  G    RR           PG 
Sbjct: 334 GGEVVGARRRRGGEERRVRGRRQGCALGSPPIPAGPAAPGRAGERRAARQWRKRGGGPGV 393

Query: 167 SPSPADPGSTSSATRVPRARRSSRRALQPRHAAPDAPGAPSRSTSQATPP-PAPRFPASR 225
           SP     G        PRAR SS   L+P  A     GAP R+   A P   AP   A  
Sbjct: 394 SPREGAQGEGVRGGVTPRARGSS-TCLRPSPATWQG-GAPYRAIFAAGPRLSAPSAEAEE 451

Query: 226 RPGA--------PRLLSRTRQRELGGSAAPSVAFSGDVTLSLERGPASAKPPP 270
            PG           L SR  +    G  +PS   +    L  E G  S    P
Sbjct: 452 VPGGHTASNPTYEPLSSRRTKAPSEGRDSPSSPATSTHYLDRESGLGSVNSHP 504


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 56.6 bits (135), Expect = 5e-08
 Identities = 73/239 (30%), Positives = 89/239 (37%), Gaps = 46/239 (19%)

Query: 101 PPFAPGRISPPAPQAFLAQRSPARASPGGGFTSAEGKRKTRPAGRGGGRTR--------R 152
           P    G  +PPA        SP   S  G    A G  +  P G+ G R          +
Sbjct: 95  PASGRGERAPPAKNT-----SPGPVSSPG---RASGTTRPGPLGQKGLRISAEETVARGK 146

Query: 153 VVAAPESAAAAPG--RSPSPADPGSTSSATRVPRARRSSRRALQPRHAAPDAPGAP---- 206
              AP+ +A + G  R  S   PG+ S A    R+R +      PR A    P  P    
Sbjct: 147 ATEAPKRSALSAGARRDTSGPTPGTPSPAM-ARRSRAAGTEVGLPRPAPSARPRPPTEGP 205

Query: 207 ----SRSTSQATPPPAPRFPASRRPGAPRLLSRTRQRELGGSAAP--SVAFSGDVTLSLE 260
               S ++  +T  P+P   A RRP A   L R   R L  SA P  S A SG       
Sbjct: 206 RKSVSSASEHSTTEPSPA--ARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTP 263

Query: 261 RGPA----------SAKPPPQVLTAEPREDATPGEGRL---PDFEKQPHSPRERLDPPP 306
           R PA           A  PPQV    PR+DA P  G L   P     P   + R  PPP
Sbjct: 264 RAPAHPSQPKPKGLQALRPPQV--TPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPP 320



 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 72/253 (28%), Positives = 91/253 (35%), Gaps = 32/253 (12%)

Query: 80  ALPLLRYPPEPGVFPFLVLWTPPFAPGRISPPAPQAFLAQRSPARASPGGGFTSAEGKRK 139
           A P  + PP     P   L +PP +P    PP     LA   P +A P    +       
Sbjct: 588 ATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLA-LPPLQAPPSPPASPPLSPLA 646

Query: 140 TRPAGRGGGRTRRVVAAPESAAAAPG-RSP--SPADPGSTSSATRVPRARRSSRRALQPR 196
           T            ++ AP S   +P  ++P   PA P  + SAT  P ++     A  P 
Sbjct: 647 TPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSAT--PPSQAPPSLAAPPL 704

Query: 197 HAAPDAPGAPSRSTSQATPPP------------APRFPASRRPGAPRLLSRTRQRELGGS 244
              P  P +P  S S ATPPP             P  P +  P +P      R   L   
Sbjct: 705 QVPPSPPASPPMSPS-ATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPL--L 761

Query: 245 AAPSVAFSGDVTLSLERGPASAKPPPQV--------LTAEPREDAT-PGEGRLPDFEKQP 295
           AAP +        SL   P  AKPPPQ         L A P   A+ PG+         P
Sbjct: 762 AAPPLQVPPSPPASLPMSPL-AKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLP 820

Query: 296 HSPRERLDPPPAP 308
            SP     PP AP
Sbjct: 821 MSPL-ATPPPQAP 832



 Score = 46.2 bits (108), Expect = 6e-05
 Identities = 92/326 (28%), Positives = 107/326 (32%), Gaps = 83/326 (25%)

Query: 82   PLLRYPPE-PGVFPFLVLWTPPFAPGRISPPAPQAFLAQRSPARASPGGGFTSAEGKRKT 140
            PL   PP+ P V    +L  PP      SPPA     A R P    P    TS  G R T
Sbjct: 823  PLATPPPQAPPVLAAPLLQVPP------SPPASPTLQAPRRPPTPGPD---TSVSGPRLT 873

Query: 141  RPAGRGGGRTRRVVAAPESAAAAPGRSPS-----PADPGSTSSATRVPRARRSSRRALQP 195
                         +A        P RSPS     P   G +SSAT  P   R        
Sbjct: 874  -------------LALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGY------ 914

Query: 196  RHAAPDAPGAPSRSTSQATPPPAPRFPASRRPGAPRLLSRTRQRELGGSAAPSVAFSGDV 255
              + P+   A       A+PPP     A      P   SR          AP +AF G  
Sbjct: 915  -DSGPEGGAA-------ASPPPDAELAACH----PAAWSR--------GPAPPLAFRGAP 954

Query: 256  TLSLE----RGPASAKPPPQVLTAEPREDATPGEGRLPDFEKQPHSPRERLDPPPAPFGQ 311
               L      GP SA     +   E  E ATP  G               LDP P+P   
Sbjct: 955  GAPLPWPPATGPGSADGLCTIYETEGPESATPAPG--------------ALDPGPSPGTS 1000

Query: 312  MILILGFRVGRGGTGSWSWR--RGAGSAELP-GCSCAQLAQQ-LARAGKSTESRNRLNGR 367
                 G +   G     S R  + A   ELP G   A + Q  L+R      +     G 
Sbjct: 1001 -----GGKAAAGAGAGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAAAEGAAGGS 1055

Query: 368  RGGVEARGGGG--GVARAERDDVLQG 391
             GG     GGG  G ARA   D   G
Sbjct: 1056 GGGPGGAEGGGVTGGARAALSDAELG 1081



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 62/236 (26%), Positives = 81/236 (34%), Gaps = 45/236 (19%)

Query: 48  NDMGTLEPTPLLRRKAA-----QLQPGRGKSCGARRAALPLLRYPPEPGVFPFLVLWTPP 102
           ++  T EP+P  RR+ +     Q    R  S  A   + P    P   G          P
Sbjct: 213 SEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGT---------P 263

Query: 103 FAPGRISPPAPQAFLAQRSPARASPGGGFTSAEGKRKTRPAGRGG--GRTRRVVAAPESA 160
            AP   S P P+   A R P    P      A G   + P       G   R V  P++A
Sbjct: 264 RAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNA 323

Query: 161 AAAPGRSPSPAD-PGSTSSATRVPRARRSSRRALQPRHAAPDAPGAPSRSTSQATPPPAP 219
           A     +P PA  P S   AT +P               AP +P AP    S  T P  P
Sbjct: 324 A-----TPLPATLPPSPPLATPLP--------------LAPPSPSAP---PSLQTLPSPP 361

Query: 220 RFPASRRPGAPRLLSRTRQRELGGSAAPSVAFSGDVTLSLERGPASAKPPPQVLTA 275
             P S+ P  P + +   Q        P +     V  SL      A P P  L++
Sbjct: 362 ATPPSQAP--PSMTTPPMQAPPSLQTIPPI----QVPHSLTSPSLQAPPSPLALSS 411



 Score = 37.4 bits (85), Expect = 0.029
 Identities = 55/203 (27%), Positives = 77/203 (37%), Gaps = 26/203 (12%)

Query: 104 APGRISPPAPQAFLAQRSPARASPGG----GFTSAEGKRK-TRPAGRGGGRTRRVVAAPE 158
           APG ++P  P +    R P   +P      G   A G++     AG  GG T      PE
Sbjct: 21  APGLLTPRPPGS---PRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGAT-----IPE 72

Query: 159 SAA-AAPGRSPSPADPGSTSSATRVPRARRSSRRALQPRHAAPDAPGAPSRSTSQATPPP 217
           SA  A P RS   A   S + A+R P + R  R A   ++ +P    +P R++   T  P
Sbjct: 73  SAPRAGPTRS---AGTSSRNPASRPPASGRGER-APPAKNTSPGPVSSPGRAS--GTTRP 126

Query: 218 APRFPASRRPGAPRLLSRTRQRELGGSAAPSVAFSGDVTLSLERGPASAKPPPQVLTAEP 277
            P      R  A   ++R +  E    +A S     D +     GP    P P +     
Sbjct: 127 GPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTS-----GPTPGTPSPAMARRSR 181

Query: 278 REDATPGEGRLPDFEKQPHSPRE 300
                 G  R P    +P  P E
Sbjct: 182 AAGTEVGLPR-PAPSARPRPPTE 203



 Score = 36.6 bits (83), Expect = 0.049
 Identities = 40/153 (26%), Positives = 49/153 (32%), Gaps = 11/153 (7%)

Query: 157 PESAAAAPGRSPSPADPGSTSSATRVPRARRSSRRALQPRHAAPDAPGAPSRSTSQATPP 216
           P  A  +P  +P P  P S   AT  P+A         P  A+P   G PS   S    P
Sbjct: 568 PLQAPPSPLTTPPPETPSSI--ATPPPQA--------PPALASPPLQGLPSPPLSPLATP 617

Query: 217 PAPRFPASRRPGAPRLLSRTRQRELGGSAAPSVAFSGDVTLSLERGPASAKP-PPQVLTA 275
           P    P    P      S      L   A PS      + + L + P S  P PP     
Sbjct: 618 PPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPF 677

Query: 276 EPREDATPGEGRLPDFEKQPHSPRERLDPPPAP 308
            P           P  +  P      L  PP+P
Sbjct: 678 SPPASPPVSPSATPPSQAPPSLAAPPLQVPPSP 710



 Score = 31.6 bits (70), Expect = 1.6
 Identities = 70/291 (24%), Positives = 89/291 (30%), Gaps = 56/291 (19%)

Query: 198 AAPDAPGAPSRSTSQATPPPAPRFPASRRPGAPRLLSRT----------RQRELGGSAAP 247
           AA   P A +       PP +PR P    P A R+L             R   +GG+  P
Sbjct: 12  AAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIP 71

Query: 248 SVAFSGDVTLSL---ERGPASAKPPP-QVLTAEPREDATPGEGRLPDFEKQPHSPRERLD 303
             A     T S     R PAS  P   +   A P ++ +PG    P         R    
Sbjct: 72  ESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPG--------RASGT 123

Query: 304 PPPAPFGQMILILGFR--VGRGGTGSWSWR-------RGAGSAELPGCSCAQLAQQLARA 354
             P P GQ  L +     V RG       R       R   S   PG     +A++   A
Sbjct: 124 TRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAA 183

Query: 355 GKSTESRNRLNGRRGGVEARGGGGGVARAERDDVLQGLGLRGTEDWCARRAPRTSSGVRR 414
           G            R      G    V+ A      +           ARR P    G++R
Sbjct: 184 GTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTE-------PSPAARRRPSAGGGLQR 236

Query: 415 GAA-----------------PGFRGSSNTARRRSIPVSLNRAQALCPPQST 448
            A+                 P  RG+       S P      QAL PPQ T
Sbjct: 237 PASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQP-KPKGLQALRPPQVT 286


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 855

 Score = 55.1 bits (131), Expect = 1e-07
 Identities = 73/241 (30%), Positives = 88/241 (36%), Gaps = 46/241 (19%)

Query: 101 PPFAPGRISPPAPQAFLAQRSPARASPGGGFTSAEGKRKTRPAGRGGGRTR--------R 152
           P    G  +PPA        SP   S  G    A G  +  P G+ G R          +
Sbjct: 95  PASGRGERAPPAKNT-----SPGPVSSPG---RASGTTRPGPLGQKGLRISAEETVARGK 146

Query: 153 VVAAPESAAAAPG--RSPSPADPGSTSSATRVPRARRSSRRALQPRHAAPDAPGAP---- 206
              AP+ +A + G  R  S   PG+ S A    R+R +      PR A    P  P    
Sbjct: 147 ATEAPKRSALSAGARRDTSGPTPGTPSPAM-ARRSRAAGTEVGLPRPAPSARPRPPTEGP 205

Query: 207 ----SRSTSQATPPPAPRFPASRRPGAPRLLSRTRQRELGGSAAP--SVAFSGDVTLSLE 260
               S ++  +T  P+P   A RRP A   L R   R L  SA P  S A SG       
Sbjct: 206 RKSVSSASEHSTTEPSPA--ARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTP 263

Query: 261 RGPA----------SAKPPPQVLTAEPREDATPGEGRLPDFEKQPHSPRERLD---PPPA 307
           R PA           A  PPQV    PR+DA P  G L        SP   L    PP  
Sbjct: 264 RAPAHPSQPKPKGLQALRPPQV--TPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTL 321

Query: 308 P 308
           P
Sbjct: 322 P 322



 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 60/229 (26%), Positives = 83/229 (36%), Gaps = 32/229 (13%)

Query: 102 PFAPGRISPPAPQAFLAQR----SPARASPGGGFTSAEGKRKTRPAGRGGGRTRRVVAAP 157
           P A G +  PA ++  +      SPAR+ P    T       ++P  +G    R     P
Sbjct: 228 PSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTP 287

Query: 158 ESAAAAPG---------RSPSPADPGSTSSATRVPRARRSSRRALQ---PRHAAPDAPGA 205
               AAP           +PSP+    + +   +P    SS    Q   P   AP +P A
Sbjct: 288 PRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSA 347

Query: 206 PSRSTSQATPPPAPRFPASRRPGAPRLLSRTRQRELGGSAAPSVAFSGDVTLSLERGPAS 265
           P    +  +PP  P   A+   G+P L       +   S  PS   S   T   +  PA 
Sbjct: 348 PPSLQTLPSPPATPPSQATTSLGSPTL-------QATHSFLPSPPLSPLATPPPQAPPAL 400

Query: 266 AKPPPQVLTAEPREDATPGEGRLPDFEKQP------HSPRERLDPPPAP 308
           A PP   L A P   A+P    L     Q       H  +    PPP+P
Sbjct: 401 ALPP---LQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSP 446



 Score = 49.3 bits (116), Expect = 7e-06
 Identities = 97/376 (25%), Positives = 120/376 (31%), Gaps = 76/376 (20%)

Query: 57  PLLRRKAAQLQPGRGKSCGARRAALPLLRYPPEPGVFPFLVLWTPPFAPGRISPPAPQAF 116
           P L     Q+ P    S     +A P  + PP     P  +   PP AP  ++ P  QA 
Sbjct: 472 PSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQAL 531

Query: 117 LAQRSPARASPGGGFTSAEGKRKTRPAGRGGGRTRRVVAAP----------ESAAAAPGR 166
               SP  + PG    S        P      +   V+AAP               AP R
Sbjct: 532 ---PSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRR 588

Query: 167 SPSPADPGSTSSATRVPRARRSSRRALQPRHAAPDAPGAPSRSTSQATPPPAPRFPASRR 226
            P+P  P ++ S  R+  A             AP  P  PSRS S     P     +S  
Sbjct: 589 PPTPG-PDTSVSGPRLTLA------------LAPGPPPPPSRSPSSTLSGPDLAGHSSSA 635

Query: 227 PGAPRLLSRTRQRELGGSA---------------------APSVAFSGDVTLSL----ER 261
              P  L        GG+A                     AP +AF G     L      
Sbjct: 636 TSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPAT 695

Query: 262 GPASAKPPPQVLTAEPREDATPGEGRLPDFEKQPHSPRERLDPPPAPFGQMILILGFRVG 321
           GP SA     +   E  E ATP  G               LDP P+P        G +  
Sbjct: 696 GPGSADGLCTIYETEGPESATPAPG--------------ALDPGPSPGTS-----GGKAA 736

Query: 322 RGGTGSWSWR--RGAGSAELP-GCSCAQLAQQ-LARAGKSTESRNRLNGRRGGVEARGGG 377
            G     S R  + A   ELP G   A + Q  L+R      +     G  GG     GG
Sbjct: 737 AGAGAGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAAAEGAAGGSGGGPGGAEGG 796

Query: 378 G--GVARAERDDVLQG 391
           G  G ARA   D   G
Sbjct: 797 GVTGGARAALSDAELG 812



 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 66/287 (22%), Positives = 87/287 (30%), Gaps = 40/287 (13%)

Query: 48  NDMGTLEPTPLLRRKAA-----QLQPGRGKSCGARRAALPLLRYPPEPGVFPFLVLWTPP 102
           ++  T EP+P  RR+ +     Q    R  S  A   + P    P   G          P
Sbjct: 213 SEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGT---------P 263

Query: 103 FAPGRISPPAPQAFLAQRSPARASPGGGFTSAEGKRKTRPAGRGGGRTRRVVAAPESAAA 162
            AP   S P P+   A R P    P      A G   + P             AP +  A
Sbjct: 264 RAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPA 323

Query: 163 APGRS--------------PSPADPGSTSSATRVPRARRSSRRA------LQPRHAAPDA 202
            P  S              PSP+ P S  +    P    S          LQ  H+   +
Sbjct: 324 TPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPS 383

Query: 203 PGAPSRSTSQATPPPAPRFPASRRPGAPRLLSRTRQRELGGSAAPSVAFSGDVTLSLERG 262
           P     +T     PPA   P  + P +P          L   A PS      + + L + 
Sbjct: 384 PPLSPLATPPPQAPPALALPPLQAPPSP-----PASPPLSPLATPSPQAPNALAVHLLQA 438

Query: 263 PASAKP-PPQVLTAEPREDATPGEGRLPDFEKQPHSPRERLDPPPAP 308
           P S  P PP      P           P  +  P      L  PP+P
Sbjct: 439 PFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSP 485



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 73/264 (27%), Positives = 85/264 (32%), Gaps = 84/264 (31%)

Query: 80  ALPLLRYPPEPGVFPFLVLWTPPFAP-GRISPPAPQAFLAQRSPARASPGGGFTSAEGKR 138
           ALP L+ PP P         +PP +P    SP AP A       A  SP           
Sbjct: 401 ALPPLQAPPSPPA-------SPPLSPLATPSPQAPNALAVHLLQAPFSPPPS-------- 445

Query: 139 KTRPAGRGGGRTRRVVAAPESAAAAPGRSPSPADPGSTSSATRVPRARRSSRRALQPRHA 198
                          V AP S  A+P  SPS   P     +   P           P   
Sbjct: 446 -------------PPVQAPFSPPASPPVSPSATPPSQAPPSLAAP-----------PLQV 481

Query: 199 APDAPGAPSRSTSQATPPPAPRFP--------ASRRPGAPRLLSRTRQRELGGSAAPSVA 250
            P  P +P  S S ATPPP    P        A   P AP  L+    + L    +P  +
Sbjct: 482 PPSPPASPPMSPS-ATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQAL---PSPPAS 537

Query: 251 FSGDV----TLSLERGPASAKPP--PQVLTA----------------EPREDATPGEGRL 288
           F G      + SL   P +  PP  P VL A                 PR   TPG    
Sbjct: 538 FPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPG---- 593

Query: 289 PDFEKQPHSPRERL----DPPPAP 308
           PD       PR  L     PPP P
Sbjct: 594 PD--TSVSGPRLTLALAPGPPPPP 615



 Score = 37.4 bits (85), Expect = 0.029
 Identities = 55/203 (27%), Positives = 77/203 (37%), Gaps = 26/203 (12%)

Query: 104 APGRISPPAPQAFLAQRSPARASPGG----GFTSAEGKRK-TRPAGRGGGRTRRVVAAPE 158
           APG ++P  P +    R P   +P      G   A G++     AG  GG T      PE
Sbjct: 21  APGLLTPRPPGS---PRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGAT-----IPE 72

Query: 159 SAA-AAPGRSPSPADPGSTSSATRVPRARRSSRRALQPRHAAPDAPGAPSRSTSQATPPP 217
           SA  A P RS   A   S + A+R P + R  R A   ++ +P    +P R++   T  P
Sbjct: 73  SAPRAGPTRS---AGTSSRNPASRPPASGRGER-APPAKNTSPGPVSSPGRAS--GTTRP 126

Query: 218 APRFPASRRPGAPRLLSRTRQRELGGSAAPSVAFSGDVTLSLERGPASAKPPPQVLTAEP 277
            P      R  A   ++R +  E    +A S     D +     GP    P P +     
Sbjct: 127 GPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTS-----GPTPGTPSPAMARRSR 181

Query: 278 REDATPGEGRLPDFEKQPHSPRE 300
                 G  R P    +P  P E
Sbjct: 182 AAGTEVGLPR-PAPSARPRPPTE 203



 Score = 31.6 bits (70), Expect = 1.6
 Identities = 70/291 (24%), Positives = 89/291 (30%), Gaps = 56/291 (19%)

Query: 198 AAPDAPGAPSRSTSQATPPPAPRFPASRRPGAPRLLSRT----------RQRELGGSAAP 247
           AA   P A +       PP +PR P    P A R+L             R   +GG+  P
Sbjct: 12  AAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIP 71

Query: 248 SVAFSGDVTLSL---ERGPASAKPPP-QVLTAEPREDATPGEGRLPDFEKQPHSPRERLD 303
             A     T S     R PAS  P   +   A P ++ +PG    P         R    
Sbjct: 72  ESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPG--------RASGT 123

Query: 304 PPPAPFGQMILILGFR--VGRGGTGSWSWR-------RGAGSAELPGCSCAQLAQQLARA 354
             P P GQ  L +     V RG       R       R   S   PG     +A++   A
Sbjct: 124 TRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAA 183

Query: 355 GKSTESRNRLNGRRGGVEARGGGGGVARAERDDVLQGLGLRGTEDWCARRAPRTSSGVRR 414
           G            R      G    V+ A      +           ARR P    G++R
Sbjct: 184 GTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTE-------PSPAARRRPSAGGGLQR 236

Query: 415 GAA-----------------PGFRGSSNTARRRSIPVSLNRAQALCPPQST 448
            A+                 P  RG+       S P      QAL PPQ T
Sbjct: 237 PASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQP-KPKGLQALRPPQVT 286


>gi|153946391 N-methyl-D-aspartate receptor subunit 2D precursor [Homo
            sapiens]
          Length = 1336

 Score = 54.7 bits (130), Expect = 2e-07
 Identities = 82/302 (27%), Positives = 106/302 (35%), Gaps = 40/302 (13%)

Query: 73   SCGARRAALPLLRYPPEPGVFPFLVLWTPPFAPGRISPPAPQAFLA----QRSPARASPG 128
            SC +  AA P  + PP P   P      P  APG  +P  P+   +    +R+     PG
Sbjct: 895  SCCSAEAAPPPAKPPPPPQPLPSPAYPAPRPAPGP-APFVPRERASVDRWRRTKGAGPPG 953

Query: 129  G-----GFTSAEGKRKTRPAGRGGGRTRRVVAAPESAAAAPGRSPSPADPGSTSSATRVP 183
            G     GF    G  + +  G G G  R   AAP  AA  P  SP  A P      +   
Sbjct: 954  GAGLADGFHRYYGPIEPQGLGLGLGEAR---AAPRGAAGRP-LSPPAAQPPQKPPPSYFA 1009

Query: 184  RARRSSRRALQPRHAAPD--APGAPSRSTSQATPPPAPRFP-ASRRPGAPRLLSRT--RQ 238
              R     A  P  A P   +P AP  + + A  PP  R       P AP    R+    
Sbjct: 1010 IVR-DKEPAEPPAGAFPGFPSPPAPPAAAATAVGPPLCRLAFEDESPPAPARWPRSDPES 1068

Query: 239  RELGGSAAPSVAFSGDVTLSLERGPA---SAKPPPQVLTAEPREDATPGEGRLPD----- 290
            + L G  A     +G         P    +A PP   L  EP    +     L       
Sbjct: 1069 QPLLGPGAGGAGGTGGAGGGAPAAPPPCRAAPPPCPYLDLEPSPSDSEDSESLGGASLGG 1128

Query: 291  -----FEKQPHSPRERLDPPPAPFGQMILILGFRVG-------RGGTGSWSWRRGAGSAE 338
                 F   P+   ERL PPP  +  +  + G+R G       R G  +W  R  A    
Sbjct: 1129 LEPWWFADFPYPYAERLGPPPGRYWSVDKLGGWRAGSWDYLPPRSGPAAWHCRHCASLEL 1188

Query: 339  LP 340
            LP
Sbjct: 1189 LP 1190



 Score = 32.7 bits (73), Expect = 0.71
 Identities = 55/217 (25%), Positives = 66/217 (30%), Gaps = 44/217 (20%)

Query: 155  AAPESAAAAPGRSP--SPADPG---STSSATRVPRARRSSRRALQPRHAAPDAPGAPSRS 209
            AAP  A   P   P  SPA P    +   A  VPR R S  R  + + A P      +  
Sbjct: 901  AAPPPAKPPPPPQPLPSPAYPAPRPAPGPAPFVPRERASVDRWRRTKGAGPPGGAGLADG 960

Query: 210  TSQATPPPAPRFPASRRPGAPRLLSRTRQRELGGSAAPSVAFSGDVTLSLERGPASAKPP 269
              +   P  P+       G    L   R    G +  P         LS        KPP
Sbjct: 961  FHRYYGPIEPQ-------GLGLGLGEARAAPRGAAGRP---------LSPPAAQPPQKPP 1004

Query: 270  PQVLT-AEPREDATPGEGRLPDFEKQPHSPRERL--------------DPPPAPF----- 309
            P        +E A P  G  P F   P  P                  + PPAP      
Sbjct: 1005 PSYFAIVRDKEPAEPPAGAFPGFPSPPAPPAAAATAVGPPLCRLAFEDESPPAPARWPRS 1064

Query: 310  -GQMILILGFRVGRGGTGSWSWRRGAGSAELPGCSCA 345
              +   +LG   G GG G      G   A  P C  A
Sbjct: 1065 DPESQPLLG--PGAGGAGGTGGAGGGAPAAPPPCRAA 1099


>gi|40353727 synaptopodin isoform A [Homo sapiens]
          Length = 903

 Score = 53.5 bits (127), Expect = 4e-07
 Identities = 65/242 (26%), Positives = 89/242 (36%), Gaps = 31/242 (12%)

Query: 100 TPPFAPGRISPPAPQAFLAQRSPARASPGGGFTSAEGKRKTRPAGRGGGRTRRVVAA--P 157
           +PP+ PG   PP+  +     SP    PG G + +       P       + R V+   P
Sbjct: 685 SPPWTPGASRPPS--SLDGWVSPGPWEPGRGSSMSSPPPLPPPPPMSPSWSERSVSPLRP 742

Query: 158 ESAAAAPGRSPSPADPGSTSSATRVPRARRSSRRALQPRHAAPDAPGAPSRSTSQATPPP 217
           E+ A  P R        +  +A R   A   S  A  PR  +P  P AP        PPP
Sbjct: 743 ETEARPPSRQLQALLARNIINAARRKSASPRSAGAENPRPFSP--PRAPPPPPPPPPPPP 800

Query: 218 APRFPASRRPGAPRLLSRTRQRELGGSAAPSVAFSGDVTLSLERGPASAKPPPQVLTAEP 277
             R P   RPG+              +A P  AF+      L  GP+S   P   L A P
Sbjct: 801 RMRSPQPARPGS--------------AAVPGAAFAPIPRSPLPAGPSSCTSPRSPLPAPP 846

Query: 278 REDATPGEGRLPDFEKQPHSPRERLDPPPAPFGQMILILGFRV-GRGGTGSWSWRRGAGS 336
           R            + + P      LD   +   +   ILG+ +  RG  GS   +RG+  
Sbjct: 847 RPFL---------YRRSPTDSDVSLDSEDSG-AKSPGILGYNICPRGWNGSLRLKRGSLP 896

Query: 337 AE 338
           AE
Sbjct: 897 AE 898



 Score = 31.2 bits (69), Expect = 2.1
 Identities = 37/132 (28%), Positives = 43/132 (32%), Gaps = 17/132 (12%)

Query: 154 VAAPESAAAAPGRSPSPADPGSTSSATRVPRARRSSRRALQPRHAAPDAPGAPSRSTSQA 213
           +A P S      R      PG TS   R P   R   R    +  AP  P  P RS    
Sbjct: 229 LAKPPSVVNRTARPFGIQAPGGTSQMERSPMLER---RHFGEKAPAPQPPSLPDRS---- 281

Query: 214 TPPPAPRFPASRRPGAPRLLSRTR-----QRELGGSAAPSVAFSGDVTLSLERGPASAKP 268
             P   R   SR P   R +   R     +R LG   AP        TLS     +  + 
Sbjct: 282 --PRPQRHIMSRSPMVERRMMGQRSPASERRPLGNFTAPPTYTE---TLSTAPLASWVRS 336

Query: 269 PPQVLTAEPRED 280
           PP      P  D
Sbjct: 337 PPSYSVLYPSSD 348


>gi|239754674 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 480

 Score = 53.1 bits (126), Expect = 5e-07
 Identities = 66/196 (33%), Positives = 81/196 (41%), Gaps = 38/196 (19%)

Query: 96  LVLWTPPFAPGRISPPAPQAFLAQRSPARASPGGGFTSAEGKRKTRPAGRG--GGRTRRV 153
           L+L  PP  P  +     +A   QR P             G + T P   G  GGR +  
Sbjct: 149 LLLELPPRPPPNLQEGGQRAIF-QRPPVYL----------GNKPTPPRQEGSFGGRPKSQ 197

Query: 154 VAAPESAAAA---PGRSPSPA---DPGSTSSATRVPRARRSSRRALQPRHAAPDAPGAPS 207
              P+  AA    PG +  PA   +PG    A+R PR R  SR A  P   AP  PGA S
Sbjct: 198 PPLPQETAAPAPQPGPTAPPARVREPGRAEGASREPRLR--SRAARPP--PAP-GPGALS 252

Query: 208 R-STSQATPPPAPRFPASRRPGAPRLLSRTRQRE---LGGSAAPSVA------FSGDVTL 257
           R S S+A   P P F    +  APR       R    LG +A PS A       SG  T+
Sbjct: 253 RASRSRAAGRPGPGFHGGEKAAAPRAPGGGGGRNPGALGRAAPPSRARQDAWGLSGCATV 312

Query: 258 SLERG----PASAKPP 269
            L RG      S++PP
Sbjct: 313 GLRRGDCDRAGSSQPP 328



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 68/252 (26%), Positives = 84/252 (33%), Gaps = 79/252 (31%)

Query: 67  QPGRGKSCGAR-----RAALPLLRYPPEPGVFPFLVLWTPPFAPGRISPPAPQAFLAQRS 121
           +PGR +          RAA P    PP PG             PG +S        A RS
Sbjct: 222 EPGRAEGASREPRLRSRAARP----PPAPG-------------PGALSR-------ASRS 257

Query: 122 PARASPGGGFTSAEGKRKTRPAGRGGGRTRRVV--AAPESAAAAPG-------------- 165
            A   PG GF   E     R  G GGGR    +  AAP S A                  
Sbjct: 258 RAAGRPGPGFHGGEKAAAPRAPGGGGGRNPGALGRAAPPSRARQDAWGLSGCATVGLRRG 317

Query: 166 ---RSPSPADPGSTSSATRVPRARRSSRRA----LQPRHA--APDAP------------- 203
              R+ S   P ++ +  R    RR  RR      +  HA   P +P             
Sbjct: 318 DCDRAGSSQPPATSGNGERCRFCRRRRRRGGGGEGEGTHATHGPASPPGRRHDEEVGAAV 377

Query: 204 -----GAPSRSTSQATPPPAPRFPASRRPGAPRLL-----SRTRQRELGGSAAPSVAFSG 253
                G  SR   Q TPPP     A +R G  R L     S TR     G++ P +    
Sbjct: 378 LRAGSGEGSRRGLQLTPPPRRVHGALQRFGGGRNLKSNWMSTTRTPRRSGASGPKMV--A 435

Query: 254 DVTLSLERGPAS 265
           D T  + R P +
Sbjct: 436 DQTSGISRPPTA 447


>gi|14602435 Williams Beuren syndrome chromosome region 14 isoform
           beta [Homo sapiens]
          Length = 833

 Score = 52.4 bits (124), Expect = 9e-07
 Identities = 56/221 (25%), Positives = 78/221 (35%), Gaps = 21/221 (9%)

Query: 82  PLLRYPPEPGVFPFLVLWTPPFAPGRISPPAPQAFLAQRSPARASPGGGFTSAEGKRKTR 141
           P    PP PGV P       P  P  +  PAP  F     P    P G    A G   + 
Sbjct: 436 PFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPF-----PIELLPLGYSEPAFGPCFSM 490

Query: 142 PAGRGGGRTRRVVAAPESAAAAPGRSPSPADPGSTSSATRVPRARRSSRRALQPRHAAPD 201
           P G+    + R   A     A    SP P   GS +             +AL+P   +  
Sbjct: 491 PRGKPPAPSPRGQKASPPTLAPATASP-PTTAGSNNPCLTQLLTAAKPEQALEPPLVSST 549

Query: 202 ---APGAPSRS-----------TSQATPPPAPRFPASRRPGAPRLLSRTRQRELGGSAAP 247
              +PG+P  +           T   TPP  P  PA+  P  P L+ +  +      +  
Sbjct: 550 LLRSPGSPQETVPEFPCTFLPPTPAPTPPRPPPGPATLAPSRPLLVPKAERLSPPAPSGS 609

Query: 248 SVAFSGDVTLSLERGPASAK-PPPQVLTAEPREDATPGEGR 287
               SGD++     G  S +  PPQ + +  R D+   E R
Sbjct: 610 ERRLSGDLSSMPGPGTLSVRVSPPQPILSRGRPDSNKTENR 650



 Score = 30.4 bits (67), Expect = 3.5
 Identities = 41/161 (25%), Positives = 57/161 (35%), Gaps = 31/161 (19%)

Query: 170 PADPGSTSSATRVPRARRSSRRALQPRHAAPDAPGAPSRSTSQATPP--PAPRFPASRRP 227
           P  P ++S+ T +     S    LQ R++ P    + +  +S    P  P PR P    P
Sbjct: 338 PEVPPASSAMTHL-----SGHSRLQARNSCPGPLDSSAFLSSDFLLPEDPKPRLPPP--P 390

Query: 228 GAPRLLSRTRQRELGG----------SAAPSVAFSGDVTLSLERGPASAKPPPQVLTAEP 277
             P LL      ++ G            AP  A   +  L   R P    PP        
Sbjct: 391 VPPPLLHYPPPAKVPGLEPCPPPPFPPMAPPTALLQEEPLFSPRFPFPTVPP-------- 442

Query: 278 REDATPGEGRLPDFEKQPHSPRERLDPPPAPFGQMILILGF 318
                PG   LP     P +P+    P P PF   +L LG+
Sbjct: 443 ----APGVSPLPAPAAFPPTPQSVPSPAPTPFPIELLPLGY 479


>gi|14602433 Williams Beuren syndrome chromosome region 14 isoform
           alpha [Homo sapiens]
          Length = 852

 Score = 52.4 bits (124), Expect = 9e-07
 Identities = 56/221 (25%), Positives = 78/221 (35%), Gaps = 21/221 (9%)

Query: 82  PLLRYPPEPGVFPFLVLWTPPFAPGRISPPAPQAFLAQRSPARASPGGGFTSAEGKRKTR 141
           P    PP PGV P       P  P  +  PAP  F     P    P G    A G   + 
Sbjct: 436 PFPTVPPAPGVSPLPAPAAFPPTPQSVPSPAPTPF-----PIELLPLGYSEPAFGPCFSM 490

Query: 142 PAGRGGGRTRRVVAAPESAAAAPGRSPSPADPGSTSSATRVPRARRSSRRALQPRHAAPD 201
           P G+    + R   A     A    SP P   GS +             +AL+P   +  
Sbjct: 491 PRGKPPAPSPRGQKASPPTLAPATASP-PTTAGSNNPCLTQLLTAAKPEQALEPPLVSST 549

Query: 202 ---APGAPSRS-----------TSQATPPPAPRFPASRRPGAPRLLSRTRQRELGGSAAP 247
              +PG+P  +           T   TPP  P  PA+  P  P L+ +  +      +  
Sbjct: 550 LLRSPGSPQETVPEFPCTFLPPTPAPTPPRPPPGPATLAPSRPLLVPKAERLSPPAPSGS 609

Query: 248 SVAFSGDVTLSLERGPASAK-PPPQVLTAEPREDATPGEGR 287
               SGD++     G  S +  PPQ + +  R D+   E R
Sbjct: 610 ERRLSGDLSSMPGPGTLSVRVSPPQPILSRGRPDSNKTENR 650



 Score = 30.4 bits (67), Expect = 3.5
 Identities = 41/161 (25%), Positives = 57/161 (35%), Gaps = 31/161 (19%)

Query: 170 PADPGSTSSATRVPRARRSSRRALQPRHAAPDAPGAPSRSTSQATPP--PAPRFPASRRP 227
           P  P ++S+ T +     S    LQ R++ P    + +  +S    P  P PR P    P
Sbjct: 338 PEVPPASSAMTHL-----SGHSRLQARNSCPGPLDSSAFLSSDFLLPEDPKPRLPPP--P 390

Query: 228 GAPRLLSRTRQRELGG----------SAAPSVAFSGDVTLSLERGPASAKPPPQVLTAEP 277
             P LL      ++ G            AP  A   +  L   R P    PP        
Sbjct: 391 VPPPLLHYPPPAKVPGLEPCPPPPFPPMAPPTALLQEEPLFSPRFPFPTVPP-------- 442

Query: 278 REDATPGEGRLPDFEKQPHSPRERLDPPPAPFGQMILILGF 318
                PG   LP     P +P+    P P PF   +L LG+
Sbjct: 443 ----APGVSPLPAPAAFPPTPQSVPSPAPTPFPIELLPLGY 479


>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
          Length = 2752

 Score = 52.4 bits (124), Expect = 9e-07
 Identities = 77/353 (21%), Positives = 131/353 (37%), Gaps = 49/353 (13%)

Query: 107 RISPPAPQAFLAQRSPARASPGGGFTSAEGKRKTRPAGRGGGRTRRVVAAPESAAAAPGR 166
           R + PAP++  A RS +  S     TS   + ++R A      T     +P  A+   G 
Sbjct: 249 RSTTPAPKSRRAHRSTSADSASSSDTS---RSRSRSAAAKTHTTALAGRSPSPASGRRGE 305

Query: 167 SPSP-ADPGSTSS--------ATRVPRARRSSRRALQPRHAAPDAPGAPSRSTSQATPPP 217
             +P ++PG+TS+        AT+ P +    +   +   +A     +P RS++   PP 
Sbjct: 306 GDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPA 365

Query: 218 APRFPASRRPGAPRLLSRTRQRELGGSAAPSVAFSGDVTLSLERGPASAKPPPQVLTAEP 277
                A R  G+P+ L+ T   +        V    + + + +R P  +   P+ L    
Sbjct: 366 PTPLLAERHGGSPQPLATTPLSQ------EPVNPPSEASPTRDRSPPKS---PEKLPQSS 416

Query: 278 REDATPGEGRLPDFEKQPHSPRERLDPPPAPFGQMILILGFRVGRGGTGSWSWRRGAGSA 337
             +++P   +     +   S  E   P PAP     +          +   S  R  G A
Sbjct: 417 SSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREI---------SSSPTSKNRSHGRA 467

Query: 338 ELPGCSCAQLAQQLARA-----GKSTESRNRLNGRRGGVEARGGGGGVARAERDDVLQGL 392
           +         ++++ R+      K   SR+R   +RG   +R               Q  
Sbjct: 468 KRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSP-------------QWR 514

Query: 393 GLRGTEDWCARRAPRTSSGVRRGAAPGFRGSSNTARR-RSIPVSLNRAQALCP 444
             R  + W   R+P+     R    PG+  S NT RR RS      R+ +  P
Sbjct: 515 RSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSP 567



 Score = 52.4 bits (124), Expect = 9e-07
 Identities = 86/368 (23%), Positives = 134/368 (36%), Gaps = 81/368 (22%)

Query: 113  PQAFLAQRSPARASPGGGFTSAEGKRKTRPAGRGGGRTRRVVAAPESAAAAPGRSPSPAD 172
            P A   +RS + +SP       + K KTR   R   R+         +  +P RS S + 
Sbjct: 1549 PSASPQERSESDSSP-------DSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSS 1601

Query: 173  PGSTSSATRVPRARRSSRRALQPRHAAPDA---------------PGAPSRSTSQATPPP 217
            P         PRA+  S  + +P+  AP A               P     S+++++P  
Sbjct: 1602 PEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEH 1661

Query: 218  APRFPASRRPG----APRLLSRTRQRELGGSAAPSV------------AFSGDVTLSLER 261
             P+   +RR       P+  SRT  R     ++P +            A S   T S  R
Sbjct: 1662 PPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRS--R 1719

Query: 262  GPASAKPPPQVLTAEPREDATPGEGRLPDFEKQPHSPR----ERLDPPPAPFGQMILILG 317
             P   +  P V + EP E +     R     +   SPR     R    P+P  + +    
Sbjct: 1720 TPPRHRRSPSVSSPEPAEKSRSSRRR-----RSASSPRTKTTSRRGRSPSPKPRGLQRSR 1774

Query: 318  FRVGRGGTGSWSWRRGAGSAELPGCSCAQLAQQLARAGKSTESRNRLNGRRGGVEARGGG 377
             R  R  T +   R  +GS           +Q  +R  + + SR+R+  RR     RGG 
Sbjct: 1775 SRSRREKTRTTRRRDRSGS-----------SQSTSRRRQRSRSRSRVTRRR-----RGGS 1818

Query: 378  GGVARAERDDVLQGLGLRGTEDWCARRAPRTSSGVRRGAAPGFRGSSNTARRRSIPVSLN 437
            G  +R+                   + + RTSS  RRG +     S   +R R+ P    
Sbjct: 1819 GYHSRSP----------------ARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWK 1862

Query: 438  RAQALCPP 445
            R+++   P
Sbjct: 1863 RSRSRASP 1870



 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 56/224 (25%), Positives = 82/224 (36%), Gaps = 31/224 (13%)

Query: 106  GRISPPAPQAFLAQRSPARASPGGGFTSAEGKRKTRPAGRGGGRTRRVVAAPESAAAAPG 165
            G +S PAP    +      AS G    SA    +     R    +    ++  S++++  
Sbjct: 2492 GMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSS 2551

Query: 166  RSPSPADPGSTSSATRVPRARRSSRRALQPRHAAPDAPG---APSRSTSQATPP-PAP-- 219
             S S     S S  + +P         +QP  A    P    AP  +  +  PP P P  
Sbjct: 2552 SSSSSGSSSSDSEGSSLP---------VQPEVALKRVPSPTPAPKEAVREGRPPEPTPAK 2602

Query: 220  ---RFPASRRPGAPRLLSRTRQRELGGSAAPSVAFSGDVTLSLERGPASAKPPPQVL--T 274
               R  +S    +    S +       S++ S + S   + S    P+ AKP PQ L   
Sbjct: 2603 RKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKP 2662

Query: 275  AEPREDATPGEGR----------LPDFEKQPHSPRERLDPPPAP 308
            A P++   PGE R          L D     +SP ER  P P P
Sbjct: 2663 ASPKK-PPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQP 2705



 Score = 40.0 bits (92), Expect = 0.004
 Identities = 80/334 (23%), Positives = 117/334 (35%), Gaps = 53/334 (15%)

Query: 120 RSPARASPGGGFTSAEGKRKTRPAGRGGGRTRRVVAAPESAAAAPGRSPSPADPGSTSSA 179
           RSP R             R      RG  R+ R   +   + A  GRS S        S 
Sbjct: 526 RSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSR 585

Query: 180 TRVPRARRSSRRALQPRHAAPDAPGAPSRSTSQATPPPAPRFPASRRPGAPRLLSRTRQR 239
           +R P  RRS  R    R +    P    RS S+    PA R   +R P   R  SR+  R
Sbjct: 586 SRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRT---PARRRSRTRSPVRRRSRSRSPAR 642

Query: 240 ELGGSAAPSVAFSGDVTLSLERGPASAKPPPQVLTAEPREDATPGEGRLPDFEKQPHSPR 299
             G S + + A          RG + ++ P +              GR         S R
Sbjct: 643 RSGRSRSRTPA---------RRGRSRSRTPAR-------------RGRSRSRTPARRSGR 680

Query: 300 ERLDPPPAPFGQMILILGFRVGRGGTGSWSWRRG---AGSAELPGCSCAQLAQQLARAGK 356
            R   P                RG + S + RRG   + S    G S ++  Q+  R+G 
Sbjct: 681 SRSRTP--------------ARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGS 726

Query: 357 STESRNRLNGRRGGVEARGGGGGVARAERDDVLQGLGLRGTEDWCARRAPRTSSGVRR-- 414
           S+E +N+   R     +R       +  R    +   L        R   ++   +RR  
Sbjct: 727 SSERKNK--SRTSQRRSRSNSSPEMKKSRISSRRSRSLSS-----PRSKAKSRLSLRRSL 779

Query: 415 -GAAPGFRGSSNTARRRSIPVSLN-RAQALCPPQ 446
            G++P  +  S T  RRS   S   +A++  PP+
Sbjct: 780 SGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPR 813



 Score = 40.0 bits (92), Expect = 0.004
 Identities = 40/145 (27%), Positives = 54/145 (37%), Gaps = 2/145 (1%)

Query: 111 PAPQAFLAQRSPARASPGGGFTSAEGKRKTRPAGRGGGRTRRVVAAPESAAAAPGRSPS- 169
           PA +     R+PAR       T A  + ++R   R   R+R       S +  P R  S 
Sbjct: 567 PATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSR 626

Query: 170 PADPGSTSSATRVPRARRSSRRALQPRHAAPDAPGAPSRSTSQATPPPAPRFPASR-RPG 228
              P    S +R P  R    R+  P          P+R     +  PA R   SR R  
Sbjct: 627 TRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTP 686

Query: 229 APRLLSRTRQRELGGSAAPSVAFSG 253
           A R  SR+R    G S + S+   G
Sbjct: 687 ARRGRSRSRTPRRGRSRSRSLVRRG 711



 Score = 38.1 bits (87), Expect = 0.017
 Identities = 90/368 (24%), Positives = 129/368 (35%), Gaps = 54/368 (14%)

Query: 107  RISPPAPQAFLAQRSPARASPGGGFTSAEGKRKTRPAGRGGGRTRRVVAAPESAAAAPGR 166
            R S  +P+     R+P R       +S      TR A R   R+R   ++PE+ +  P R
Sbjct: 1670 RGSRSSPEPKTKSRTPPRRR-----SSRSSPELTRKA-RLSRRSRSASSSPETRSRTPPR 1723

Query: 167  --------SPSPADPGSTSSATR---VPRARRSSRRALQPRHAAPDAPGAPSRSTSQATP 215
                    SP PA+   +S   R    PR + +SRR   P         + SRS  + T 
Sbjct: 1724 HRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTR 1783

Query: 216  PPAPR------FPASRRPGAPRLLSRTRQRELGGSA--APSVAFSGDVTLSLERGPASAK 267
                R         SRR    R  SR  +R  GGS   + S A       S  R    ++
Sbjct: 1784 TTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSR 1843

Query: 268  PPPQVLTAEPREDATPGEGRLPDFEKQPHSPRERLDPPPAPFGQMILILGFRVGRGGTGS 327
             PP       R   +P   +       P + R      P        ++  R  R  T  
Sbjct: 1844 TPP-TSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTP--------LISRRRSRSRTSP 1894

Query: 328  WSWRRGAGSAELPGCSCAQLAQQLARAGKSTESRNRLNGRRGGVEARGGGGGV------A 381
             S RR          S   + ++ +R+  S  SR R   R   V  R            +
Sbjct: 1895 VSRRRSR--------SRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRS 1946

Query: 382  RAERDDVLQGLGLRGTEDWCARRA-PRTSSGVRRGAAPGFRGSSNTARR---RSIPVSLN 437
            R+    V +      T     RR+  RTS   RR +    R S  T RR   R+ PV+  
Sbjct: 1947 RSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITRRRSRS--RTSPVTRRRSRSRTSPVTRR 2004

Query: 438  RAQALCPP 445
            R+++   P
Sbjct: 2005 RSRSRTSP 2012



 Score = 38.1 bits (87), Expect = 0.017
 Identities = 52/199 (26%), Positives = 68/199 (34%), Gaps = 12/199 (6%)

Query: 112  APQAFLAQRSPARASPGGGFTSAEGKRKTRPAGRGGGRTRRVVAAPESAAAAPGRSPSPA 171
            AP A LA R PA ++      SA              RT      P +AAA    SP  A
Sbjct: 2223 APAANLASRIPAASAAAMNLASARTPAIPTAVNLADSRT------PAAAAAMNLASPRTA 2276

Query: 172  DPGSTSSATRVPRARRSSRRALQPRHAAPDAPGAPSRSTSQATPPPAPRFP-ASRRPGAP 230
                  SA  +   R  +  A+    A   A  A    T   TPP A  +P +SR P AP
Sbjct: 2277 ---VAPSAVNLADPRTPTAPAVNLAGARTPAALAALSLTGSGTPPTAANYPSSSRTPQAP 2333

Query: 231  RLLSRTRQRELGGSAAPSVAFSGDVTLSLERGPASAKPPPQVLTAEPREDATP--GEGRL 288
               +    R    +A  ++A S            SA+  P +  A       P     R+
Sbjct: 2334 ASANLVGPRSAHATAPVNIAGSRTAAALAPASLTSARMAPALSGANLTSPRVPLSAYERV 2393

Query: 289  PDFEKQPHSPRERLDPPPA 307
                  P   R R   PP+
Sbjct: 2394 SGRTSPPLLDRARSRTPPS 2412



 Score = 37.7 bits (86), Expect = 0.022
 Identities = 46/172 (26%), Positives = 62/172 (36%), Gaps = 10/172 (5%)

Query: 100  TPPFAPGRISPPAPQAFLAQRSPARASPGGGFTSAEGKRKTRPAGRGGGRTRRVVAAPES 159
            TPP    R S         +RS +R SP    T    + +T P  R   R+R    +P +
Sbjct: 1962 TPPVTRRR-SRSRTSPITRRRSRSRTSP---VTRRRSRSRTSPVTRRRSRSR---TSPVT 2014

Query: 160  AAAAPGRSPSPADPGSTSSATRVPRARRSSRRALQPRHAAPDAPGAPSRSTSQAT-PPPA 218
               +  R+P      S S    +PR R  SR  L  R  +       +R     T  PPA
Sbjct: 2015 RRRSRSRTPPAIRRRSRSRTPLLPRKRSRSRSPLAIRRRSRSRTPRTARGKRSLTRSPPA 2074

Query: 219  PRFPASRRPGAPRLLSRT--RQRELGGSAAPSVAFSGDVTLSLERGPASAKP 268
             R  ++    + R  S T    R   GS  P VA +        R   S  P
Sbjct: 2075 IRRRSASGSSSDRSRSATPPATRNHSGSRTPPVALNSSRMSCFSRPSMSPTP 2126



 Score = 36.2 bits (82), Expect = 0.064
 Identities = 40/140 (28%), Positives = 53/140 (37%), Gaps = 24/140 (17%)

Query: 119  QRSPARASPGGGFTSAEGKRKTRPAGRGGGRTRRVVAAPESAAAAP------GRSPSPAD 172
            +RS +RASP    +    + +T P  R   R+R       S +  P       RS +P  
Sbjct: 1909 RRSRSRASP---VSRRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRSRSRTPPV 1965

Query: 173  PGSTSSATRVPRARRSSRRALQP----RHAAPDAPGAPSRSTSQA-----------TPPP 217
                S +   P  RR SR    P    R  +  +P    RS S+            TPP 
Sbjct: 1966 TRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTPPA 2025

Query: 218  APRFPASRRPGAPRLLSRTR 237
              R   SR P  PR  SR+R
Sbjct: 2026 IRRRSRSRTPLLPRKRSRSR 2045



 Score = 35.8 bits (81), Expect = 0.083
 Identities = 48/200 (24%), Positives = 76/200 (38%), Gaps = 28/200 (14%)

Query: 106  GRISPPAPQAFLAQRSPARASPGGGFTSAEGKRKTRPAGRGGGRTRRVVAAPESAAAAPG 165
            GR    +P   LA RSP R           G+    P  + G        +PE +     
Sbjct: 1097 GRSRSSSPVTELASRSPIRQD--------RGEFSASPMLKSG-------MSPEQSRFQSD 1141

Query: 166  RSPSPA-DPGSTSSATRVPRARRSSRRALQPRHAAPDAPGAPSRSTSQATPPPAPRFPAS 224
             S  P  D  S    +R+  A    + AL P+    DA  +P R   + +P P    P S
Sbjct: 1142 SSSYPTVDSNSLLGQSRLETAESKEKMALPPQE---DATASPPRQKDKFSPFPVQDRPES 1198

Query: 225  RRPGAPRLLSRTRQRELGGSAAPSVAFSGDVTLS------LERGPASAKPPPQV---LTA 275
                   L +  R+R   GS+  +   +  +  S      +E    S +P  Q+   L++
Sbjct: 1199 SLVFKDTLRTPPRERSGAGSSPETKEQNSALPTSSQDEELMEVVEKSEEPAGQILSHLSS 1258

Query: 276  EPREDATPGEGRLPDFEKQP 295
            E +E +T      P+ E++P
Sbjct: 1259 ELKEMSTSNFESSPEVEERP 1278



 Score = 35.8 bits (81), Expect = 0.083
 Identities = 43/160 (26%), Positives = 64/160 (40%), Gaps = 19/160 (11%)

Query: 149  RTRRVVAAPESAAAAPGRSPSPADPGSTSSATRVPRARRSSRRALQPRHAAPDAPGAPSR 208
            R RR  ++  S++++   S S +   S+SS++    +  SS  +  P  A P  P A  +
Sbjct: 2603 RKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKP-GPQALPK 2661

Query: 209  STSQATPPPAPRFPASRRPGAPRLLSRTRQRELGGSAAPSVAFSGDVTLSLERGPASAKP 268
              S   PPP  R   SR P  P + S    R L  S              +ER   S +P
Sbjct: 2662 PASPKKPPPGER--RSRSPRKP-IDSLRDSRSLSYS-------------PVERRRPSPQP 2705

Query: 269  PPQVLTAEPREDATPGEGRLPDFEKQPHSPRERLDPPPAP 308
             P+   +   E  +   G+  D  + P   R R  P P P
Sbjct: 2706 SPRDQQSSSSERGS-RRGQRGD-SRSPSHKRRRETPSPRP 2743



 Score = 35.0 bits (79), Expect = 0.14
 Identities = 36/142 (25%), Positives = 53/142 (37%), Gaps = 21/142 (14%)

Query: 106  GRISPPAPQAFLAQRSPARASPGGGFTSAEGKRKTRPAGRGGGRTRRVVAAPESAAAAPG 165
            G  +PP    + +     +A              T P    G RT   +A P S  +A  
Sbjct: 2313 GSGTPPTAANYPSSSRTPQAPASANLVGPRSAHATAPVNIAGSRTAAALA-PASLTSA-- 2369

Query: 166  RSPSPADPGSTSSATRVPRA--RRSSRRALQP-----RHAAPDAPGAPSRSTSQATPPPA 218
               +PA  G+  ++ RVP +   R S R   P     R   P +  + SR TS+  P P+
Sbjct: 2370 -RMAPALSGANLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPSPS 2428

Query: 219  PRF----------PASRRPGAP 230
             R           PA  +P +P
Sbjct: 2429 SRMGQAPSQSLLPPAQDQPRSP 2450



 Score = 34.7 bits (78), Expect = 0.19
 Identities = 67/274 (24%), Positives = 89/274 (32%), Gaps = 42/274 (15%)

Query: 28   SNAQFLLRRRGMSKCDKIMCNDMGTLEPTPLLRRKAAQLQPGRGKSCGARRAALPLLRYP 87
            S +   +RRR  S+  +            P +RR++A      G S    R+A P     
Sbjct: 2044 SRSPLAIRRRSRSRTPRTARGKRSLTRSPPAIRRRSAS-----GSSSDRSRSATP----- 2093

Query: 88   PEPGVFPFLVLWTPPFA--PGRIS-----PPAPQAFLAQRSPARASPGGG-------FTS 133
              P         TPP A    R+S       +P      RSP    P G           
Sbjct: 2094 --PATRNHSGSRTPPVALNSSRMSCFSRPSMSPTPLDRCRSPGMLEPLGSSRTPMSVLQQ 2151

Query: 134  AEGKRKTRPAGRGGGRTRRVV----AAPESAAAAPGRSPSPADPGSTSSATRVPRARRSS 189
            A G     P  R     R  V    A    A A    S   A P  + SA  +  AR S 
Sbjct: 2152 AGGSMMDGPGPRIPDHQRTSVPENHAQSRIALALTAISLGTARPPPSMSAAGLA-ARMSQ 2210

Query: 190  RRALQPRHAAPDAPGAPSRSTSQATPPPAPRFPASRRPGAPRLLSRTRQRELGGSAAPSV 249
              A  P  +   AP A   S   A    A    ++R P  P  ++    R    +AA ++
Sbjct: 2211 VPAPVPLMSLRTAPAANLASRIPAASAAAMNLASARTPAIPTAVNLADSRTPAAAAAMNL 2270

Query: 250  AFSGDVTLSLERGPASAKPPPQVLTAEPREDATP 283
            A            P +A  P  V  A+PR    P
Sbjct: 2271 A-----------SPRTAVAPSAVNLADPRTPTAP 2293



 Score = 34.3 bits (77), Expect = 0.24
 Identities = 31/102 (30%), Positives = 39/102 (38%), Gaps = 23/102 (22%)

Query: 166  RSPSPADPGSTSSATRVP--RARRSSRRALQPRHAAP-------------DAPGAPSRST 210
            RS S + P       R P  R+R  S   L+     P             D P  PSR  
Sbjct: 1418 RSSSASSPEMKDGLPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGR 1477

Query: 211  SQATPPPAPRF------PASRRPGAPRLLSR--TRQRELGGS 244
            S+    P P+       P SR P +P L ++  T QRE  GS
Sbjct: 1478 SECDSSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGS 1519



 Score = 33.1 bits (74), Expect = 0.54
 Identities = 33/120 (27%), Positives = 45/120 (37%), Gaps = 24/120 (20%)

Query: 111  PAPQAFLAQRSPARASPGGGFTSAEGKRKTRPAGR--GGGRTRRVVAAPESAAAAPGRSP 168
            P PQA     SP +  PG        +R++R   +     R  R ++        P   P
Sbjct: 2654 PGPQALPKPASPKKPPPG--------ERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQP 2705

Query: 169  SPADPGSTSSATRVPRARRSSRRALQPRHAAPDAPGAPSRSTSQATPPPAP-RFPASRRP 227
            SP D  S+SS     R +R   R             +PS    + TP P P R  +SR P
Sbjct: 2706 SPRDQQSSSSERGSRRGQRGDSR-------------SPSHKRRRETPSPRPMRHRSSRSP 2752



 Score = 31.6 bits (70), Expect = 1.6
 Identities = 44/203 (21%), Positives = 75/203 (36%), Gaps = 11/203 (5%)

Query: 48  NDMGTLEPTPLLRRKAAQLQPGRGKSCGARRAALPLLRYPPEPGVFPFLVLWTPP--FAP 105
           N    ++ + +  R++  L   R K+    ++ L L R        P     TPP     
Sbjct: 744 NSSPEMKKSRISSRRSRSLSSPRSKA----KSRLSLRRSLSGSSPCPKQKSQTPPRRSRS 799

Query: 106 GRISPPAPQAFLAQRSPARASPGGGFTSAEGKRKTRPAGRGGGRTRRVVAAPESAAAAPG 165
           G   P A      +RS + +SP     S    R++  +     + +      + +  +P 
Sbjct: 800 GSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQ 859

Query: 166 RSPSPADPGSTSSATRVPRARRSSRRALQPRHAAPDAPGAPSRSTSQATPPPAPRFPASR 225
            +     P   S     P     SR     RH+   +  +P R  S   P  +P   +S 
Sbjct: 860 ANEQSVTPQRRSCFESSPDPELKSRTP--SRHSCSGS--SPPRVKSSTPPRQSPSRSSSP 915

Query: 226 RPGAPRLLSRTRQRELGGSAAPS 248
           +P    ++S  RQR   GS++PS
Sbjct: 916 QPKVKAIIS-PRQRSHSGSSSPS 937



 Score = 30.8 bits (68), Expect = 2.7
 Identities = 32/148 (21%), Positives = 53/148 (35%), Gaps = 14/148 (9%)

Query: 106  GRISPPAP-----QAFLAQRSPARASPGGGFTSAEGKRKTRPAGRGGGRTRRVVAAPESA 160
            GR   P P     ++  +  S + +S     +S+     +  +      +    ++P  A
Sbjct: 2593 GRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPA 2652

Query: 161  AAAPGRSPSPADPGSTSSATRVPRARRSSRRALQPRHAAPDAPGAPSRSTSQATPPPAPR 220
               P   P PA P       + P   R SR   +P  +  D+         +  P P P 
Sbjct: 2653 KPGPQALPKPASP------KKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPS 2706

Query: 221  FPASRRPGAPRLLSRTRQRELGGSAAPS 248
             P  ++  +    SR  QR  G S +PS
Sbjct: 2707 -PRDQQSSSSERGSRRGQR--GDSRSPS 2731



 Score = 30.0 bits (66), Expect = 4.6
 Identities = 49/201 (24%), Positives = 68/201 (33%), Gaps = 26/201 (12%)

Query: 107 RISPPAPQAFLAQRSPARASPGGGFTSAEGKRKTRPAGRGGGRTRRVVAAPESAAAAPGR 166
           R   PA +     R+PAR       T A      R +GR   RT        S     GR
Sbjct: 648 RSRTPARRGRSRSRTPARRGRSRSRTPA------RRSGRSRSRTPARRGRSRSRTPRRGR 701

Query: 167 SPSPADPGSTSSATRVPRARRSSRRALQPRHAAPDAPGAPSRSTSQATPPPAPRFPASRR 226
           S S +      S +R P+ R  S  + + ++ +     +  RS S ++P       +SRR
Sbjct: 702 SRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRT---SQRRSRSNSSPEMKKSRISSRR 758

Query: 227 PGAPRLLSRTRQRELGGSAAPSVAFSGDVTLSLERGPASAKP-PPQVLTAEPREDATPGE 285
               R LS  R +                 LSL R  + + P P Q     PR   +   
Sbjct: 759 ---SRSLSSPRSK-------------AKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSS 802

Query: 286 GRLPDFEKQPHSPRERLDPPP 306
                    P   R    PPP
Sbjct: 803 QPKAKSRTPPRRSRSSSSPPP 823


>gi|54860079 nadrin isoform 1 [Homo sapiens]
          Length = 881

 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 62/250 (24%), Positives = 82/250 (32%), Gaps = 45/250 (18%)

Query: 104 APGRISPPAPQAFLAQRSPARASPGGGFTSAEGKRKT-------------RPAGRGGGRT 150
           +PG  SPP P+  ++   PA         S + + +                AG      
Sbjct: 570 SPGDGSPPKPKDPVSAAVPAPGRNNSQIASGQNQPQAAAGSHQLSMGQPHNAAGPSPHTL 629

Query: 151 RRVVAAPESAAAAPGRSPSPADPGSTSSA--------------TRVPRARRSSRRALQPR 196
           RR V  P  A   PG +P P  PG  SS+              TR P            +
Sbjct: 630 RRAVKKPAPAPPKPG-NPPPGHPGGQSSSGTSQHPPSLSPKPPTRSPSPPTQHTGQPPGQ 688

Query: 197 HAAPDAPGAPSRSTSQATPPPAPRFPASRRPGAPRLLSRTRQRELGGSAAPSVAFSGDVT 256
            +AP    AP R +S  +P  AP  P  + P     L  T+    G     ++     + 
Sbjct: 689 PSAPSQLSAPRRYSSSLSPIQAPNHPPPQPPTQATPLMHTKPNSQGPPNPMALPSEHGLE 748

Query: 257 LSLERGPASAKPP--------------PQVLTAEPREDATPGEGRLPDFEKQPHSPRER- 301
                 P +  PP              PQ L     E A P  G LP     P  PR R 
Sbjct: 749 QPSHTPPQTPTPPSTPPLGKQNPSLPAPQTLAGGNPETAQPHAGTLPRPRPVP-KPRNRP 807

Query: 302 -LDPPPAPFG 310
            + PPP P G
Sbjct: 808 SVPPPPQPPG 817



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 62/241 (25%), Positives = 87/241 (36%), Gaps = 37/241 (15%)

Query: 101 PPFAPGRISPPAPQAFLAQRSPARASPGGGFTSAEGKRKTRPAGRGGGRTRRVVAAPESA 160
           PP     + P  P+    Q S A +S GGG   +      +    G G   +      +A
Sbjct: 528 PPTDGSTVVPAGPEP-PPQSSRAESSSGGGTVPSSAGILEQGPSPGDGSPPKPKDPVSAA 586

Query: 161 AAAPGRSPS---------PADPGSTSSATRVPR-----ARRSSRRALQPRHAAPDAPGAP 206
             APGR+ S          A  GS   +   P      +  + RRA++    AP  PG P
Sbjct: 587 VPAPGRNNSQIASGQNQPQAAAGSHQLSMGQPHNAAGPSPHTLRRAVKKPAPAPPKPGNP 646

Query: 207 ---------SRSTSQATPPPAPRFPASRRPGAPRLLSRTRQRELGGSAAPSVAFSGDVTL 257
                    S  TSQ  P  +P+ P +R P  P     T Q     SA   ++     + 
Sbjct: 647 PPGHPGGQSSSGTSQHPPSLSPK-PPTRSPSPP--TQHTGQPPGQPSAPSQLSAPRRYSS 703

Query: 258 SLERGPASAKPPPQ-------VLTAEPREDATPGEGRLPD---FEKQPHSPRERLDPPPA 307
           SL    A   PPPQ       ++  +P     P    LP     E+  H+P +   PP  
Sbjct: 704 SLSPIQAPNHPPPQPPTQATPLMHTKPNSQGPPNPMALPSEHGLEQPSHTPPQTPTPPST 763

Query: 308 P 308
           P
Sbjct: 764 P 764


>gi|122937496 WAS/WASL interacting protein family, member 3 [Homo
           sapiens]
          Length = 483

 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 73/278 (26%), Positives = 101/278 (36%), Gaps = 45/278 (16%)

Query: 51  GTLEPTPLLRRKAAQ------LQPGRGKSCGARRAALPLLRYPPEPGVFPFLVLWTPPFA 104
           G+  P+P L  K           P  G +  A  AA      PP P V P     TPP  
Sbjct: 127 GSRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTA---PPRPNV-PAPPPPTPPPP 182

Query: 105 PGRISPPAPQAFLAQRSPARASPGGGFTSAEGKRKTRPAGRGGGRTRRVVAAPESAAAAP 164
           P  + PP P +    ++P  + PG             P  +G      VVA P   A  P
Sbjct: 183 PPPLPPPLPSSSPI-KTPLVSPPG-------------PLTKGN---LPVVAPPVPCAPPP 225

Query: 165 GRSPSPADPGSTSSATRVPRARRSSRRALQPRHAAPDAP--------GAPSRSTSQATPP 216
              P P  P     A+ +  + ++ +  L P H  P  P        G P      A+P 
Sbjct: 226 PPPPPPPTPPPLPPASVL--SDKAVKPQLAPLHLPPIPPPLPLLPPCGYPGLKAEPASPA 283

Query: 217 PAPRFPASRRPGAPRLLSRTRQRELGGSAAPSVAFSGDVTLSLERGPASAKPPPQVLTAE 276
              + P +  P  P   S + +  L     P V  S +    L     S + PPQ   A+
Sbjct: 284 QDAQEPPAPPPPLPPYASCSPRASLPAPPLPGVNSSSETPPPLPPKSPSFQAPPQKAGAQ 343

Query: 277 --PREDATPGEGRLPDFEKQPH----SPRERLDPPPAP 308
             P   A PG    P  +K+ H    +   +L+PPPAP
Sbjct: 344 ALPAPPAPPGSQ--PFLQKKRHGRPGAGGGKLNPPPAP 379


>gi|110815800 WD repeat domain 32 [Homo sapiens]
          Length = 559

 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 41/116 (35%), Positives = 48/116 (41%), Gaps = 14/116 (12%)

Query: 142 PAGRGGGRTRRVVAAPESAAAAPGRSPSPADPGSTSSATRVPRARRSSRR------ALQP 195
           P G G          P    AA    PSP  PG+   AT  P   RS RR      +  P
Sbjct: 9   PGGDGSAGAGAEEPTPHEGQAAATGPPSPLHPGA--DATHPPPPARSPRRPGAPSLSPAP 66

Query: 196 RHAAPDAPGAPSRSTSQATPPPAPRFPASRRPGAPRLLSRTRQRE-----LGGSAA 246
           R      PGAP  ST+ A   P+P  P  RRPG P   +++R R      LGG  A
Sbjct: 67  RSGELGLPGAPESSTASAPGEPSPPSPPCRRPG-PDCRAKSRGRHGLGAGLGGPGA 121



 Score = 40.4 bits (93), Expect = 0.003
 Identities = 34/101 (33%), Positives = 39/101 (38%), Gaps = 14/101 (13%)

Query: 169 SPADPGSTSSATRVPRARRSSRRALQPRHAAPDAPGAPSRSTSQATPPPAPRFPASRRPG 228
           SP   GS  +    P        A  P   +P  PGA +       PPP  R P  RRPG
Sbjct: 8   SPGGDGSAGAGAEEPTPHEGQAAATGP--PSPLHPGADATH-----PPPPARSP--RRPG 58

Query: 229 APRLLSRTRQRELGGSAAPSVAFSGDVTLSLERGPASAKPP 269
           AP L    R  ELG   AP  +     T S    P+   PP
Sbjct: 59  APSLSPAPRSGELGLPGAPESS-----TASAPGEPSPPSPP 94


>gi|182507165 thymus expressed gene 3-like [Homo sapiens]
          Length = 629

 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 88/307 (28%), Positives = 112/307 (36%), Gaps = 61/307 (19%)

Query: 111 PAPQAFLAQRSP-ARASPGGGFTSAE------GKRKTRPAG--RGGGRTRRVVAAPESAA 161
           P  Q  + QR P A  SPG    + E      G   T PA   R    +    AAPE AA
Sbjct: 279 PRRQNSVRQRPPDASPSPGSARPAREPSLERVGGHPTSPAALSRAWASSWESEAAPEPAA 338

Query: 162 --AAPGRSPSPADPGSTSSATRVPRARRSSRRALQPRHAAPDAPGAPSRSTSQATPPPAP 219
             AAP    SPA+ G    A  +P A+ ++R    P  AA   P   +R  S    PP  
Sbjct: 339 PPAAPSPPDSPAE-GRLVKAQYIPGAQAATRGL--PGRAARRKPPPLTRGRSVEQSPPRE 395

Query: 220 RFPASRRPGAPRLLSRTRQRELGGSAAPSVAFSGDVTLSLERGPASAKPPPQVLTAEPRE 279
           R  A+ R G  R+   + +R  G   A   + S   T  L R  A    PP+  TAE   
Sbjct: 396 RPRAAGRRG--RMAEASGRR--GSPRARKASRSQSETSLLGRASAVPSGPPKYPTAE--- 448

Query: 280 DATPGEGRLPDFEKQPHSPRERLDPPPAPFGQMILILGFRVGRGGTGSW----------- 328
                        ++P  PR R  P P    Q           G    W           
Sbjct: 449 ------------REEPRPPRPRRGPAPTLAAQ---------AAGSCRRWRSTAEIDAADG 487

Query: 329 -SWRRGAGSAELPGCSCAQLAQQ----LARAGKSTE-SRNRLN--GRRGGVEARGGGGGV 380
              R  A +A +PG   +  A Q       AG  +E S  RL   GRRG     GGG G 
Sbjct: 488 RRVRPRAPAARVPGPGPSPSAPQRRLLYGCAGSDSECSAGRLGPLGRRGPAGGVGGGYGE 547

Query: 381 ARAERDD 387
           + +   +
Sbjct: 548 SESSASE 554



 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 63/226 (27%), Positives = 80/226 (35%), Gaps = 22/226 (9%)

Query: 102 PFAPGRISPPA--PQAFLAQRSPARASPGG-GFTSAEGKRKTRPAGRGGGRTRRVVAAPE 158
           P AP  +   A  P++F A    A  S G    +SAE + +  P           + +P 
Sbjct: 171 PSAPEVVGARAAVPRSFSAPYPTAGGSAGPEACSSAERRARAGPFLTPSPLHAVAMRSPR 230

Query: 159 SAAAAPGRSPSPADPGSTSSATRVPRARRSSRR-ALQPRHAAPDAPGAPSRSTS-QATPP 216
                P  SP     G           RR  RR A QPR +   A G P R  S +  PP
Sbjct: 231 PCGRPPTDSPDAGGAGRPLDGYISALLRRRRRRGAGQPRTSPGGADGGPRRQNSVRQRPP 290

Query: 217 PAPRFPASRRPGAPRLLSRTRQRELGGSAAPSVAFSGDVTLSLERGPASAKPPPQVLTAE 276
            A   P S RP     L R     +GG      A S     S E   + A P P    A 
Sbjct: 291 DASPSPGSARPAREPSLER-----VGGHPTSPAALSRAWASSWE---SEAAPEPAAPPAA 342

Query: 277 PREDATPGEGRLPDFEKQPHSP---------RERLDPPPAPFGQMI 313
           P    +P EGRL   +  P +            R  PPP   G+ +
Sbjct: 343 PSPPDSPAEGRLVKAQYIPGAQAATRGLPGRAARRKPPPLTRGRSV 388



 Score = 37.4 bits (85), Expect = 0.029
 Identities = 56/228 (24%), Positives = 76/228 (33%), Gaps = 24/228 (10%)

Query: 25  PLGSNAQFLLRRRGMSKCDKIMCNDMGTLEPTPLLRRKAAQLQPGRGKSCG-ARRAALPL 83
           PL      LLRRR      +   +  G  +  P  +    Q  P    S G AR A  P 
Sbjct: 248 PLDGYISALLRRRRRRGAGQPRTSPGGA-DGGPRRQNSVRQRPPDASPSPGSARPAREPS 306

Query: 84  LR----YPPEPGVFP--FLVLWTPPFAPGRISPPAPQA----------FLAQRSPARASP 127
           L     +P  P      +   W    AP   +PPA  +            AQ  P   + 
Sbjct: 307 LERVGGHPTSPAALSRAWASSWESEAAPEPAAPPAAPSPPDSPAEGRLVKAQYIPGAQAA 366

Query: 128 GGGFTSAEGKRKTRPAGRGGGRTRRVVAAPESAAAAPGRSPSPADPGSTSSATRVPRARR 187
             G      +RK  P  RG    +   + P     A GR    A+      + R  +A R
Sbjct: 367 TRGLPGRAARRKPPPLTRGRSVEQ---SPPRERPRAAGRRGRMAEASGRRGSPRARKASR 423

Query: 188 SSRRALQPRHAAPDAPGAPSRSTSQATPPPAPRFPASRRPGAPRLLSR 235
           S         A+    G P   T++   P  PR    RR  AP L ++
Sbjct: 424 SQSETSLLGRASAVPSGPPKYPTAEREEPRPPR---PRRGPAPTLAAQ 468


>gi|14589876 embryonal Fyn-associated substrate isoform 2 [Homo
           sapiens]
          Length = 468

 Score = 50.4 bits (119), Expect = 3e-06
 Identities = 69/263 (26%), Positives = 94/263 (35%), Gaps = 52/263 (19%)

Query: 82  PLLRYPPEP---GVFPFLVLWTPPFAPGRISP---------PAPQAFLAQRSPARASPGG 129
           PL R  P+P      P+ V  TP   P  + P         P P  + A  +  RAS   
Sbjct: 79  PLTRVAPQPPGEDDAPYDVPLTPK-PPAELEPDLEWEGGREPGPPIYAAPSNLKRAS--A 135

Query: 130 GFTSAEGKRKTRPAGRGGGRTRRVVAAPESAAAAPGRSPSPADPGSTSS----------- 178
                E   +    G GGG    +   P     AP   PSP  PG+ +S           
Sbjct: 136 LLNLYEAPEELLADGEGGGTDEGIYDVPLLGPEAP---PSPEPPGALASHDQDTLAQLLA 192

Query: 179 -------ATRVPRARRSSRRALQPRHAAPDAPG-------APSRSTS---QATPPPAPRF 221
                    R+P A   SRR L P    P+AP        AP R  S   +  PPP PR 
Sbjct: 193 RSPPPPHRPRLPSAESLSRRPL-PALPVPEAPSPSPVPSPAPGRKGSIQDRPLPPPPPRL 251

Query: 222 PASRRPGAPRLLSRTRQRELGGSAAPSVAFSGDVTLSLERGPASAKPPPQVLTAEPREDA 281
           P     G P++      RE+    A        + ++ E      K   +   + P + A
Sbjct: 252 PGY---GGPKVEGDPEGREMEDDPAGHHNEYEGIPMAEEYDYVHLKGMDKAQGSRPPDQA 308

Query: 282 TPGEGRLPDFEKQPHSPRERLDP 304
             G+  LP  E+   +P+E L P
Sbjct: 309 CTGDPELP--ERGMPAPQEALSP 329


>gi|5031681 embryonal Fyn-associated substrate isoform 1 [Homo
           sapiens]
          Length = 561

 Score = 50.4 bits (119), Expect = 3e-06
 Identities = 69/263 (26%), Positives = 94/263 (35%), Gaps = 52/263 (19%)

Query: 82  PLLRYPPEP---GVFPFLVLWTPPFAPGRISP---------PAPQAFLAQRSPARASPGG 129
           PL R  P+P      P+ V  TP   P  + P         P P  + A  +  RAS   
Sbjct: 172 PLTRVAPQPPGEDDAPYDVPLTPK-PPAELEPDLEWEGGREPGPPIYAAPSNLKRAS--A 228

Query: 130 GFTSAEGKRKTRPAGRGGGRTRRVVAAPESAAAAPGRSPSPADPGSTSS----------- 178
                E   +    G GGG    +   P     AP   PSP  PG+ +S           
Sbjct: 229 LLNLYEAPEELLADGEGGGTDEGIYDVPLLGPEAP---PSPEPPGALASHDQDTLAQLLA 285

Query: 179 -------ATRVPRARRSSRRALQPRHAAPDAPG-------APSRSTS---QATPPPAPRF 221
                    R+P A   SRR L P    P+AP        AP R  S   +  PPP PR 
Sbjct: 286 RSPPPPHRPRLPSAESLSRRPL-PALPVPEAPSPSPVPSPAPGRKGSIQDRPLPPPPPRL 344

Query: 222 PASRRPGAPRLLSRTRQRELGGSAAPSVAFSGDVTLSLERGPASAKPPPQVLTAEPREDA 281
           P     G P++      RE+    A        + ++ E      K   +   + P + A
Sbjct: 345 PGY---GGPKVEGDPEGREMEDDPAGHHNEYEGIPMAEEYDYVHLKGMDKAQGSRPPDQA 401

Query: 282 TPGEGRLPDFEKQPHSPRERLDP 304
             G+  LP  E+   +P+E L P
Sbjct: 402 CTGDPELP--ERGMPAPQEALSP 422


>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
          Length = 1270

 Score = 50.1 bits (118), Expect = 4e-06
 Identities = 45/205 (21%), Positives = 69/205 (33%), Gaps = 8/205 (3%)

Query: 105 PGRISPPAPQAFLAQRSPARASPGGGFTSAEGKRKTRPAGRGGGRTRRVVAAPESAAAAP 164
           P   +P  P      + PA  +P     +      T P       T+     P+  A   
Sbjct: 208 PALTTPKEPTP-TTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTT 266

Query: 165 GRSPSPADPGSTS-SATRVPRARRSSRRALQPRHAAPDAPGAPSRSTSQATPPPAPRFPA 223
            + P+P  P   + + T+ P    +      P+  AP  P  P+ +T +   P  P+ P 
Sbjct: 267 TKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPT 326

Query: 224 SRRPGAPRLLSRTRQRELGGSAAPSVAFSGDVTLSLERGPASAKPPPQVLTAEPREDATP 283
              P  P   ++          AP+       T   E  P + K P    T EP    TP
Sbjct: 327 PTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEP-SPTTP 385

Query: 284 GEGRLPDFEKQPHSPRERLDPPPAP 308
            E      +  P + +E     PAP
Sbjct: 386 KEPAPTTTKSAPTTTKE-----PAP 405



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 59/262 (22%), Positives = 85/262 (32%), Gaps = 48/262 (18%)

Query: 52  TLEPTPLLRRKAAQLQPGRGKSCGARRAALPLLRYPPEPGVFPFLVLWTPPFAPGRISPP 111
           T EP P   ++ A   P +      +    P    P EP   P       P  P   +P 
Sbjct: 423 TKEPAPTTPKEPAPTTPKKPAPTTPKE---PAPTTPKEPA--PTTTKKPAPTTPKEPAPT 477

Query: 112 APQAFLAQRSPARASPGGGFTSAEGKRKTRPAGRGGGRTRRVVAAPESAAAAPGRSPSPA 171
            P+   A  +P + +P    T+ E    T P        +     PE  A      P+P 
Sbjct: 478 TPKE-TAPTTPKKLTP----TTPEKLAPTTPE-------KPAPTTPEELAPTTPEEPTPT 525

Query: 172 DPGSTSSATRVPRARRSSRRALQPRHAAPDAPGAPSRSTSQATPP-----PAPRFPASRR 226
            P   +  T              P+ AAP+ P  P+ +T +   P     PAP  P    
Sbjct: 526 TPEEPAPTT--------------PKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETA 571

Query: 227 PGAPRLLSRTRQRELGGSAAPSVAFSGDVTLSLERGPASAKPPPQVLTAEPREDATPGEG 286
           P  P+  + T  +E   +     A         E  P + K P      +P      G  
Sbjct: 572 PTTPKGTAPTTLKEPAPTTPKKPA-------PKELAPTTTKEPTSTTCDKPAPTTPKGTA 624

Query: 287 RLPDFEKQPHSPRERLDPPPAP 308
                E  P +P+E     PAP
Sbjct: 625 PTTPKEPAPTTPKE-----PAP 641



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 61/261 (23%), Positives = 80/261 (30%), Gaps = 39/261 (14%)

Query: 52  TLEPTPLLRRKAAQLQPGRGKSCGARRAALPLLRYPPEPGVFPFLVLWTPPFAPGRISPP 111
           T EP P   + A    P   K         P    P EP         T P  P   +P 
Sbjct: 283 TKEPAPTTTKSA----PTTPKEPAPTTPKKPAPTTPKEPAP-------TTPKEPTPTTPK 331

Query: 112 APQAFLAQRSPARASPGGGFTSAEGKRKTRPAGRGGGRTRRVVAAPESAAAAPGRSPSPA 171
            P      + PA  +P     +A  K            T      P+  A    + PSP 
Sbjct: 332 EPAP--TTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTT------PKEPAPTTTKEPSPT 383

Query: 172 DPGSTSSATRVPRARRSSRRALQPRHAAPDAPGAPSRSTSQATPPPAPRFPASRRPGAPR 231
            P   +  T       +   A     +AP  P  PS +T++   P  P+ PA   P  P 
Sbjct: 384 TPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKP- 442

Query: 232 LLSRTRQRELGGSAAPSVAFSGDVTLSLERGPASAKPPPQVLTAEPREDATPGEGRLPDF 291
                         AP+       T   E  P + K P      EP    TP E      
Sbjct: 443 --------------APTTPKEPAPTTPKEPAPTTTKKPAPTTPKEP-APTTPKETAPTTP 487

Query: 292 EKQPHSPRERLDP----PPAP 308
           +K   +  E+L P     PAP
Sbjct: 488 KKLTPTTPEKLAPTTPEKPAP 508



 Score = 39.3 bits (90), Expect = 0.008
 Identities = 51/251 (20%), Positives = 83/251 (33%), Gaps = 27/251 (10%)

Query: 54  EPTPLLRRKAAQLQPGRGKSCGARRAALPLLRYPPEPGVFPFLVLWTPPFAPGRISPPAP 113
           EPTP    + A   P   K+        P    P EP   P       P  P   +P  P
Sbjct: 521 EPTPTTPEEPAPTTP---KAAAPNTPKEPAPTTPKEPA--PTTPKEPAPTTPKETAPTTP 575

Query: 114 QAFL-------AQRSPARASPGGGFTSAEGKRKTRPAGRGGGRTRRVVA--APESAAAAP 164
           +          A  +P + +P     +   +  +    +    T +  A   P+  A   
Sbjct: 576 KGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTT 635

Query: 165 GRSPSPADPGSTSSATRVPRARRSSRRALQPRHAAPDAPGAPSRSTSQATPPPAPRFPAS 224
            + P+P  P  T+  T    A  + ++   P+  AP     P+ +TS    P  P+  A 
Sbjct: 636 PKEPAPTTPKGTAPTTLKEPAPTTPKKPA-PKELAPTTTKGPTSTTSDKPAPTTPKETAP 694

Query: 225 RRPGAPRLLSRTRQRELGGSAAP------SVAFSGDVTLSLERGP------ASAKPPPQV 272
             P  P   +  +         P      S   +     ++ + P       SA+P P+ 
Sbjct: 695 TTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKA 754

Query: 273 LTAEPREDATP 283
           L   P+E   P
Sbjct: 755 LENSPKEPGVP 765



 Score = 32.7 bits (73), Expect = 0.71
 Identities = 30/118 (25%), Positives = 48/118 (40%), Gaps = 10/118 (8%)

Query: 180 TRVPRARRSSRRALQPRHAAPDAPGAPSRSTSQATPPPAPRFPASRRPGAPRLLSRTRQR 239
           T  P+ R ++ +A  P+   P    AP + TS   P   PR    +    PR ++ T   
Sbjct: 870 TAKPKDRATNSKATTPKPQKPTK--APKKPTSTKKPKTMPRVRKPKTTPTPRKMTST-MP 926

Query: 240 ELGGSAAPSVAFSGDVTLSLERGPASAKPPPQVLTAEPR-EDATPGEGRLPDFEKQPH 296
           EL  ++  + A     T        +  P  +++   P+ EDA   EG  P    +PH
Sbjct: 927 ELNPTSRIAEAMLQTTT------RPNQTPNSKLVEVNPKSEDAGGAEGETPHMLLRPH 978


>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
          Length = 1311

 Score = 50.1 bits (118), Expect = 4e-06
 Identities = 45/205 (21%), Positives = 69/205 (33%), Gaps = 8/205 (3%)

Query: 105 PGRISPPAPQAFLAQRSPARASPGGGFTSAEGKRKTRPAGRGGGRTRRVVAAPESAAAAP 164
           P   +P  P      + PA  +P     +      T P       T+     P+  A   
Sbjct: 249 PALTTPKEPTP-TTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTT 307

Query: 165 GRSPSPADPGSTS-SATRVPRARRSSRRALQPRHAAPDAPGAPSRSTSQATPPPAPRFPA 223
            + P+P  P   + + T+ P    +      P+  AP  P  P+ +T +   P  P+ P 
Sbjct: 308 TKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPT 367

Query: 224 SRRPGAPRLLSRTRQRELGGSAAPSVAFSGDVTLSLERGPASAKPPPQVLTAEPREDATP 283
              P  P   ++          AP+       T   E  P + K P    T EP    TP
Sbjct: 368 PTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEP-SPTTP 426

Query: 284 GEGRLPDFEKQPHSPRERLDPPPAP 308
            E      +  P + +E     PAP
Sbjct: 427 KEPAPTTTKSAPTTTKE-----PAP 446



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 59/262 (22%), Positives = 85/262 (32%), Gaps = 48/262 (18%)

Query: 52  TLEPTPLLRRKAAQLQPGRGKSCGARRAALPLLRYPPEPGVFPFLVLWTPPFAPGRISPP 111
           T EP P   ++ A   P +      +    P    P EP   P       P  P   +P 
Sbjct: 464 TKEPAPTTPKEPAPTTPKKPAPTTPKE---PAPTTPKEPA--PTTTKKPAPTTPKEPAPT 518

Query: 112 APQAFLAQRSPARASPGGGFTSAEGKRKTRPAGRGGGRTRRVVAAPESAAAAPGRSPSPA 171
            P+   A  +P + +P    T+ E    T P        +     PE  A      P+P 
Sbjct: 519 TPKE-TAPTTPKKLTP----TTPEKLAPTTPE-------KPAPTTPEELAPTTPEEPTPT 566

Query: 172 DPGSTSSATRVPRARRSSRRALQPRHAAPDAPGAPSRSTSQATPP-----PAPRFPASRR 226
            P   +  T              P+ AAP+ P  P+ +T +   P     PAP  P    
Sbjct: 567 TPEEPAPTT--------------PKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETA 612

Query: 227 PGAPRLLSRTRQRELGGSAAPSVAFSGDVTLSLERGPASAKPPPQVLTAEPREDATPGEG 286
           P  P+  + T  +E   +     A         E  P + K P      +P      G  
Sbjct: 613 PTTPKGTAPTTLKEPAPTTPKKPA-------PKELAPTTTKEPTSTTCDKPAPTTPKGTA 665

Query: 287 RLPDFEKQPHSPRERLDPPPAP 308
                E  P +P+E     PAP
Sbjct: 666 PTTPKEPAPTTPKE-----PAP 682



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 61/261 (23%), Positives = 80/261 (30%), Gaps = 39/261 (14%)

Query: 52  TLEPTPLLRRKAAQLQPGRGKSCGARRAALPLLRYPPEPGVFPFLVLWTPPFAPGRISPP 111
           T EP P   + A    P   K         P    P EP         T P  P   +P 
Sbjct: 324 TKEPAPTTTKSA----PTTPKEPAPTTPKKPAPTTPKEPAP-------TTPKEPTPTTPK 372

Query: 112 APQAFLAQRSPARASPGGGFTSAEGKRKTRPAGRGGGRTRRVVAAPESAAAAPGRSPSPA 171
            P      + PA  +P     +A  K            T      P+  A    + PSP 
Sbjct: 373 EPAP--TTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTT------PKEPAPTTTKEPSPT 424

Query: 172 DPGSTSSATRVPRARRSSRRALQPRHAAPDAPGAPSRSTSQATPPPAPRFPASRRPGAPR 231
            P   +  T       +   A     +AP  P  PS +T++   P  P+ PA   P  P 
Sbjct: 425 TPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKP- 483

Query: 232 LLSRTRQRELGGSAAPSVAFSGDVTLSLERGPASAKPPPQVLTAEPREDATPGEGRLPDF 291
                         AP+       T   E  P + K P      EP    TP E      
Sbjct: 484 --------------APTTPKEPAPTTPKEPAPTTTKKPAPTTPKEP-APTTPKETAPTTP 528

Query: 292 EKQPHSPRERLDP----PPAP 308
           +K   +  E+L P     PAP
Sbjct: 529 KKLTPTTPEKLAPTTPEKPAP 549



 Score = 39.3 bits (90), Expect = 0.008
 Identities = 51/251 (20%), Positives = 83/251 (33%), Gaps = 27/251 (10%)

Query: 54  EPTPLLRRKAAQLQPGRGKSCGARRAALPLLRYPPEPGVFPFLVLWTPPFAPGRISPPAP 113
           EPTP    + A   P   K+        P    P EP   P       P  P   +P  P
Sbjct: 562 EPTPTTPEEPAPTTP---KAAAPNTPKEPAPTTPKEPA--PTTPKEPAPTTPKETAPTTP 616

Query: 114 QAFL-------AQRSPARASPGGGFTSAEGKRKTRPAGRGGGRTRRVVA--APESAAAAP 164
           +          A  +P + +P     +   +  +    +    T +  A   P+  A   
Sbjct: 617 KGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTT 676

Query: 165 GRSPSPADPGSTSSATRVPRARRSSRRALQPRHAAPDAPGAPSRSTSQATPPPAPRFPAS 224
            + P+P  P  T+  T    A  + ++   P+  AP     P+ +TS    P  P+  A 
Sbjct: 677 PKEPAPTTPKGTAPTTLKEPAPTTPKKPA-PKELAPTTTKGPTSTTSDKPAPTTPKETAP 735

Query: 225 RRPGAPRLLSRTRQRELGGSAAP------SVAFSGDVTLSLERGP------ASAKPPPQV 272
             P  P   +  +         P      S   +     ++ + P       SA+P P+ 
Sbjct: 736 TTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKA 795

Query: 273 LTAEPREDATP 283
           L   P+E   P
Sbjct: 796 LENSPKEPGVP 806



 Score = 32.7 bits (73), Expect = 0.71
 Identities = 30/118 (25%), Positives = 48/118 (40%), Gaps = 10/118 (8%)

Query: 180  TRVPRARRSSRRALQPRHAAPDAPGAPSRSTSQATPPPAPRFPASRRPGAPRLLSRTRQR 239
            T  P+ R ++ +A  P+   P    AP + TS   P   PR    +    PR ++ T   
Sbjct: 911  TAKPKDRATNSKATTPKPQKPTK--APKKPTSTKKPKTMPRVRKPKTTPTPRKMTST-MP 967

Query: 240  ELGGSAAPSVAFSGDVTLSLERGPASAKPPPQVLTAEPR-EDATPGEGRLPDFEKQPH 296
            EL  ++  + A     T        +  P  +++   P+ EDA   EG  P    +PH
Sbjct: 968  ELNPTSRIAEAMLQTTT------RPNQTPNSKLVEVNPKSEDAGGAEGETPHMLLRPH 1019


>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
          Length = 1363

 Score = 50.1 bits (118), Expect = 4e-06
 Identities = 45/205 (21%), Positives = 69/205 (33%), Gaps = 8/205 (3%)

Query: 105 PGRISPPAPQAFLAQRSPARASPGGGFTSAEGKRKTRPAGRGGGRTRRVVAAPESAAAAP 164
           P   +P  P      + PA  +P     +      T P       T+     P+  A   
Sbjct: 301 PALTTPKEPTP-TTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTT 359

Query: 165 GRSPSPADPGSTS-SATRVPRARRSSRRALQPRHAAPDAPGAPSRSTSQATPPPAPRFPA 223
            + P+P  P   + + T+ P    +      P+  AP  P  P+ +T +   P  P+ P 
Sbjct: 360 TKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPT 419

Query: 224 SRRPGAPRLLSRTRQRELGGSAAPSVAFSGDVTLSLERGPASAKPPPQVLTAEPREDATP 283
              P  P   ++          AP+       T   E  P + K P    T EP    TP
Sbjct: 420 PTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEP-SPTTP 478

Query: 284 GEGRLPDFEKQPHSPRERLDPPPAP 308
            E      +  P + +E     PAP
Sbjct: 479 KEPAPTTTKSAPTTTKE-----PAP 498



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 59/262 (22%), Positives = 85/262 (32%), Gaps = 48/262 (18%)

Query: 52  TLEPTPLLRRKAAQLQPGRGKSCGARRAALPLLRYPPEPGVFPFLVLWTPPFAPGRISPP 111
           T EP P   ++ A   P +      +    P    P EP   P       P  P   +P 
Sbjct: 516 TKEPAPTTPKEPAPTTPKKPAPTTPKE---PAPTTPKEPA--PTTTKKPAPTTPKEPAPT 570

Query: 112 APQAFLAQRSPARASPGGGFTSAEGKRKTRPAGRGGGRTRRVVAAPESAAAAPGRSPSPA 171
            P+   A  +P + +P    T+ E    T P        +     PE  A      P+P 
Sbjct: 571 TPKE-TAPTTPKKLTP----TTPEKLAPTTPE-------KPAPTTPEELAPTTPEEPTPT 618

Query: 172 DPGSTSSATRVPRARRSSRRALQPRHAAPDAPGAPSRSTSQATPP-----PAPRFPASRR 226
            P   +  T              P+ AAP+ P  P+ +T +   P     PAP  P    
Sbjct: 619 TPEEPAPTT--------------PKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETA 664

Query: 227 PGAPRLLSRTRQRELGGSAAPSVAFSGDVTLSLERGPASAKPPPQVLTAEPREDATPGEG 286
           P  P+  + T  +E   +     A         E  P + K P      +P      G  
Sbjct: 665 PTTPKGTAPTTLKEPAPTTPKKPA-------PKELAPTTTKEPTSTTCDKPAPTTPKGTA 717

Query: 287 RLPDFEKQPHSPRERLDPPPAP 308
                E  P +P+E     PAP
Sbjct: 718 PTTPKEPAPTTPKE-----PAP 734



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 61/261 (23%), Positives = 80/261 (30%), Gaps = 39/261 (14%)

Query: 52  TLEPTPLLRRKAAQLQPGRGKSCGARRAALPLLRYPPEPGVFPFLVLWTPPFAPGRISPP 111
           T EP P   + A    P   K         P    P EP         T P  P   +P 
Sbjct: 376 TKEPAPTTTKSA----PTTPKEPAPTTPKKPAPTTPKEPAP-------TTPKEPTPTTPK 424

Query: 112 APQAFLAQRSPARASPGGGFTSAEGKRKTRPAGRGGGRTRRVVAAPESAAAAPGRSPSPA 171
            P      + PA  +P     +A  K            T      P+  A    + PSP 
Sbjct: 425 EPAP--TTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTT------PKEPAPTTTKEPSPT 476

Query: 172 DPGSTSSATRVPRARRSSRRALQPRHAAPDAPGAPSRSTSQATPPPAPRFPASRRPGAPR 231
            P   +  T       +   A     +AP  P  PS +T++   P  P+ PA   P  P 
Sbjct: 477 TPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKP- 535

Query: 232 LLSRTRQRELGGSAAPSVAFSGDVTLSLERGPASAKPPPQVLTAEPREDATPGEGRLPDF 291
                         AP+       T   E  P + K P      EP    TP E      
Sbjct: 536 --------------APTTPKEPAPTTPKEPAPTTTKKPAPTTPKEP-APTTPKETAPTTP 580

Query: 292 EKQPHSPRERLDP----PPAP 308
           +K   +  E+L P     PAP
Sbjct: 581 KKLTPTTPEKLAPTTPEKPAP 601



 Score = 39.3 bits (90), Expect = 0.008
 Identities = 51/251 (20%), Positives = 83/251 (33%), Gaps = 27/251 (10%)

Query: 54  EPTPLLRRKAAQLQPGRGKSCGARRAALPLLRYPPEPGVFPFLVLWTPPFAPGRISPPAP 113
           EPTP    + A   P   K+        P    P EP   P       P  P   +P  P
Sbjct: 614 EPTPTTPEEPAPTTP---KAAAPNTPKEPAPTTPKEPA--PTTPKEPAPTTPKETAPTTP 668

Query: 114 QAFL-------AQRSPARASPGGGFTSAEGKRKTRPAGRGGGRTRRVVA--APESAAAAP 164
           +          A  +P + +P     +   +  +    +    T +  A   P+  A   
Sbjct: 669 KGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTT 728

Query: 165 GRSPSPADPGSTSSATRVPRARRSSRRALQPRHAAPDAPGAPSRSTSQATPPPAPRFPAS 224
            + P+P  P  T+  T    A  + ++   P+  AP     P+ +TS    P  P+  A 
Sbjct: 729 PKEPAPTTPKGTAPTTLKEPAPTTPKKPA-PKELAPTTTKGPTSTTSDKPAPTTPKETAP 787

Query: 225 RRPGAPRLLSRTRQRELGGSAAP------SVAFSGDVTLSLERGP------ASAKPPPQV 272
             P  P   +  +         P      S   +     ++ + P       SA+P P+ 
Sbjct: 788 TTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKA 847

Query: 273 LTAEPREDATP 283
           L   P+E   P
Sbjct: 848 LENSPKEPGVP 858



 Score = 32.7 bits (73), Expect = 0.71
 Identities = 30/118 (25%), Positives = 48/118 (40%), Gaps = 10/118 (8%)

Query: 180  TRVPRARRSSRRALQPRHAAPDAPGAPSRSTSQATPPPAPRFPASRRPGAPRLLSRTRQR 239
            T  P+ R ++ +A  P+   P    AP + TS   P   PR    +    PR ++ T   
Sbjct: 963  TAKPKDRATNSKATTPKPQKPTK--APKKPTSTKKPKTMPRVRKPKTTPTPRKMTST-MP 1019

Query: 240  ELGGSAAPSVAFSGDVTLSLERGPASAKPPPQVLTAEPR-EDATPGEGRLPDFEKQPH 296
            EL  ++  + A     T        +  P  +++   P+ EDA   EG  P    +PH
Sbjct: 1020 ELNPTSRIAEAMLQTTT------RPNQTPNSKLVEVNPKSEDAGGAEGETPHMLLRPH 1071


>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
          Length = 1404

 Score = 50.1 bits (118), Expect = 4e-06
 Identities = 45/205 (21%), Positives = 69/205 (33%), Gaps = 8/205 (3%)

Query: 105 PGRISPPAPQAFLAQRSPARASPGGGFTSAEGKRKTRPAGRGGGRTRRVVAAPESAAAAP 164
           P   +P  P      + PA  +P     +      T P       T+     P+  A   
Sbjct: 342 PALTTPKEPTP-TTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTT 400

Query: 165 GRSPSPADPGSTS-SATRVPRARRSSRRALQPRHAAPDAPGAPSRSTSQATPPPAPRFPA 223
            + P+P  P   + + T+ P    +      P+  AP  P  P+ +T +   P  P+ P 
Sbjct: 401 TKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPT 460

Query: 224 SRRPGAPRLLSRTRQRELGGSAAPSVAFSGDVTLSLERGPASAKPPPQVLTAEPREDATP 283
              P  P   ++          AP+       T   E  P + K P    T EP    TP
Sbjct: 461 PTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEP-SPTTP 519

Query: 284 GEGRLPDFEKQPHSPRERLDPPPAP 308
            E      +  P + +E     PAP
Sbjct: 520 KEPAPTTTKSAPTTTKE-----PAP 539



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 59/262 (22%), Positives = 85/262 (32%), Gaps = 48/262 (18%)

Query: 52  TLEPTPLLRRKAAQLQPGRGKSCGARRAALPLLRYPPEPGVFPFLVLWTPPFAPGRISPP 111
           T EP P   ++ A   P +      +    P    P EP   P       P  P   +P 
Sbjct: 557 TKEPAPTTPKEPAPTTPKKPAPTTPKE---PAPTTPKEPA--PTTTKKPAPTTPKEPAPT 611

Query: 112 APQAFLAQRSPARASPGGGFTSAEGKRKTRPAGRGGGRTRRVVAAPESAAAAPGRSPSPA 171
            P+   A  +P + +P    T+ E    T P        +     PE  A      P+P 
Sbjct: 612 TPKE-TAPTTPKKLTP----TTPEKLAPTTPE-------KPAPTTPEELAPTTPEEPTPT 659

Query: 172 DPGSTSSATRVPRARRSSRRALQPRHAAPDAPGAPSRSTSQATPP-----PAPRFPASRR 226
            P   +  T              P+ AAP+ P  P+ +T +   P     PAP  P    
Sbjct: 660 TPEEPAPTT--------------PKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETA 705

Query: 227 PGAPRLLSRTRQRELGGSAAPSVAFSGDVTLSLERGPASAKPPPQVLTAEPREDATPGEG 286
           P  P+  + T  +E   +     A         E  P + K P      +P      G  
Sbjct: 706 PTTPKGTAPTTLKEPAPTTPKKPA-------PKELAPTTTKEPTSTTCDKPAPTTPKGTA 758

Query: 287 RLPDFEKQPHSPRERLDPPPAP 308
                E  P +P+E     PAP
Sbjct: 759 PTTPKEPAPTTPKE-----PAP 775



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 61/261 (23%), Positives = 80/261 (30%), Gaps = 39/261 (14%)

Query: 52  TLEPTPLLRRKAAQLQPGRGKSCGARRAALPLLRYPPEPGVFPFLVLWTPPFAPGRISPP 111
           T EP P   + A    P   K         P    P EP         T P  P   +P 
Sbjct: 417 TKEPAPTTTKSA----PTTPKEPAPTTPKKPAPTTPKEPAP-------TTPKEPTPTTPK 465

Query: 112 APQAFLAQRSPARASPGGGFTSAEGKRKTRPAGRGGGRTRRVVAAPESAAAAPGRSPSPA 171
            P      + PA  +P     +A  K            T      P+  A    + PSP 
Sbjct: 466 EPAP--TTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTT------PKEPAPTTTKEPSPT 517

Query: 172 DPGSTSSATRVPRARRSSRRALQPRHAAPDAPGAPSRSTSQATPPPAPRFPASRRPGAPR 231
            P   +  T       +   A     +AP  P  PS +T++   P  P+ PA   P  P 
Sbjct: 518 TPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKP- 576

Query: 232 LLSRTRQRELGGSAAPSVAFSGDVTLSLERGPASAKPPPQVLTAEPREDATPGEGRLPDF 291
                         AP+       T   E  P + K P      EP    TP E      
Sbjct: 577 --------------APTTPKEPAPTTPKEPAPTTTKKPAPTTPKEP-APTTPKETAPTTP 621

Query: 292 EKQPHSPRERLDP----PPAP 308
           +K   +  E+L P     PAP
Sbjct: 622 KKLTPTTPEKLAPTTPEKPAP 642



 Score = 39.3 bits (90), Expect = 0.008
 Identities = 51/251 (20%), Positives = 83/251 (33%), Gaps = 27/251 (10%)

Query: 54  EPTPLLRRKAAQLQPGRGKSCGARRAALPLLRYPPEPGVFPFLVLWTPPFAPGRISPPAP 113
           EPTP    + A   P   K+        P    P EP   P       P  P   +P  P
Sbjct: 655 EPTPTTPEEPAPTTP---KAAAPNTPKEPAPTTPKEPA--PTTPKEPAPTTPKETAPTTP 709

Query: 114 QAFL-------AQRSPARASPGGGFTSAEGKRKTRPAGRGGGRTRRVVA--APESAAAAP 164
           +          A  +P + +P     +   +  +    +    T +  A   P+  A   
Sbjct: 710 KGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTT 769

Query: 165 GRSPSPADPGSTSSATRVPRARRSSRRALQPRHAAPDAPGAPSRSTSQATPPPAPRFPAS 224
            + P+P  P  T+  T    A  + ++   P+  AP     P+ +TS    P  P+  A 
Sbjct: 770 PKEPAPTTPKGTAPTTLKEPAPTTPKKPA-PKELAPTTTKGPTSTTSDKPAPTTPKETAP 828

Query: 225 RRPGAPRLLSRTRQRELGGSAAP------SVAFSGDVTLSLERGP------ASAKPPPQV 272
             P  P   +  +         P      S   +     ++ + P       SA+P P+ 
Sbjct: 829 TTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKA 888

Query: 273 LTAEPREDATP 283
           L   P+E   P
Sbjct: 889 LENSPKEPGVP 899



 Score = 32.7 bits (73), Expect = 0.71
 Identities = 30/118 (25%), Positives = 48/118 (40%), Gaps = 10/118 (8%)

Query: 180  TRVPRARRSSRRALQPRHAAPDAPGAPSRSTSQATPPPAPRFPASRRPGAPRLLSRTRQR 239
            T  P+ R ++ +A  P+   P    AP + TS   P   PR    +    PR ++ T   
Sbjct: 1004 TAKPKDRATNSKATTPKPQKPTK--APKKPTSTKKPKTMPRVRKPKTTPTPRKMTST-MP 1060

Query: 240  ELGGSAAPSVAFSGDVTLSLERGPASAKPPPQVLTAEPR-EDATPGEGRLPDFEKQPH 296
            EL  ++  + A     T        +  P  +++   P+ EDA   EG  P    +PH
Sbjct: 1061 ELNPTSRIAEAMLQTTT------RPNQTPNSKLVEVNPKSEDAGGAEGETPHMLLRPH 1112


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.133    0.406 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,505,374
Number of Sequences: 37866
Number of extensions: 1534392
Number of successful extensions: 17756
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 193
Number of HSP's successfully gapped in prelim test: 1849
Number of HSP's that attempted gapping in prelim test: 11569
Number of HSP's gapped (non-prelim): 6036
length of query: 459
length of database: 18,247,518
effective HSP length: 106
effective length of query: 353
effective length of database: 14,233,722
effective search space: 5024503866
effective search space used: 5024503866
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

CSHL Press