Search of human proteins with 10835049

Search of human proteins with 10835049

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|10835049 ras homolog gene family, member A [Homo sapiens]
         (193 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|10835049 ras homolog gene family, member A [Homo sapiens]          395   e-111
gi|111494251 ras homolog gene family, member C precursor [Homo s...   370   e-103
gi|111494248 ras homolog gene family, member C precursor [Homo s...   370   e-103
gi|28395033 ras homolog gene family, member C precursor [Homo sa...   370   e-103
gi|4757764 ras homolog gene family, member B [Homo sapiens]           337   3e-93
gi|9845511 ras-related C3 botulinum toxin substrate 1 isoform Ra...   219   1e-57
gi|46249393 ras homolog gene family, member G [Homo sapiens]          216   1e-56
gi|89903012 cell division cycle 42 isoform 1 [Homo sapiens]           213   8e-56
gi|4757952 cell division cycle 42 isoform 1 [Homo sapiens]            213   8e-56
gi|4826962 ras-related C3 botulinum toxin substrate 3 (rho famil...   211   2e-55
gi|16357472 cell division cycle 42 isoform 2 [Homo sapiens]           209   1e-54
gi|4506381 ras-related C3 botulinum toxin substrate 2 [Homo sapi...   208   3e-54
gi|9845509 ras-related C3 botulinum toxin substrate 1 isoform Ra...   207   3e-54
gi|50263042 ras-like protein TC10 [Homo sapiens]                      204   3e-53
gi|7656900 ras homolog D [Homo sapiens]                               204   4e-53
gi|4885069 ras homolog gene family, member E [Homo sapiens]           198   2e-51
gi|4885581 Rho family GTPase 2 [Homo sapiens]                         194   3e-50
gi|38016957 ras homolog gene family, member F [Homo sapiens]          192   1e-49
gi|16903164 ras homolog gene family, member J [Homo sapiens]          192   1e-49
gi|11034843 ras homolog gene family, member U [Homo sapiens]          180   8e-46
gi|7657514 GTP-binding protein RHO6 [Homo sapiens]                    167   5e-42
gi|229577148 ras homolog gene family, member V [Homo sapiens]         162   1e-40
gi|4757770 ras homolog gene family, member H [Homo sapiens]           152   1e-37
gi|237649113 Rho-related BTB domain containing 2 isoform 3 [Homo...   119   2e-27
gi|237649111 Rho-related BTB domain containing 2 isoform 2 [Homo...   119   2e-27
gi|237649109 Rho-related BTB domain containing 2 isoform 1 [Homo...   119   2e-27
gi|28629866 Rho-related BTB domain containing 1 [Homo sapiens]        117   5e-27
gi|5803135 RAB35, member RAS oncogene family [Homo sapiens]            92   3e-19
gi|21361418 RAB30, member RAS oncogene family [Homo sapiens]           92   4e-19
gi|13569962 RAB1B, member RAS oncogene family [Homo sapiens]           91   8e-19

>gi|10835049 ras homolog gene family, member A [Homo sapiens]
          Length = 193

 Score =  395 bits (1016), Expect = e-111
 Identities = 193/193 (100%), Positives = 193/193 (100%)

Query: 1   MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDT 60
           MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDT
Sbjct: 1   MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDT 60

Query: 61  AGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKD 120
           AGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKD
Sbjct: 61  AGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKD 120

Query: 121 LRNDEHTRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDGVREVFEMATRAALQ 180
           LRNDEHTRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDGVREVFEMATRAALQ
Sbjct: 121 LRNDEHTRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDGVREVFEMATRAALQ 180

Query: 181 ARRGKKKSGCLVL 193
           ARRGKKKSGCLVL
Sbjct: 181 ARRGKKKSGCLVL 193


>gi|111494251 ras homolog gene family, member C precursor [Homo
           sapiens]
          Length = 193

 Score =  370 bits (949), Expect = e-103
 Identities = 177/193 (91%), Positives = 185/193 (95%)

Query: 1   MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDT 60
           MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENY+ADIEVDGKQVELALWDT
Sbjct: 1   MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYIADIEVDGKQVELALWDT 60

Query: 61  AGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKD 120
           AGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKD
Sbjct: 61  AGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKD 120

Query: 121 LRNDEHTRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDGVREVFEMATRAALQ 180
           LR DEHTRRELAKMKQEPV+ EEGRDMANRI AFGY+ECSAKTK+GVREVFEMATRA LQ
Sbjct: 121 LRQDEHTRRELAKMKQEPVRSEEGRDMANRISAFGYLECSAKTKEGVREVFEMATRAGLQ 180

Query: 181 ARRGKKKSGCLVL 193
            R+ K++ GC +L
Sbjct: 181 VRKNKRRRGCPIL 193


>gi|111494248 ras homolog gene family, member C precursor [Homo
           sapiens]
          Length = 193

 Score =  370 bits (949), Expect = e-103
 Identities = 177/193 (91%), Positives = 185/193 (95%)

Query: 1   MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDT 60
           MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENY+ADIEVDGKQVELALWDT
Sbjct: 1   MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYIADIEVDGKQVELALWDT 60

Query: 61  AGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKD 120
           AGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKD
Sbjct: 61  AGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKD 120

Query: 121 LRNDEHTRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDGVREVFEMATRAALQ 180
           LR DEHTRRELAKMKQEPV+ EEGRDMANRI AFGY+ECSAKTK+GVREVFEMATRA LQ
Sbjct: 121 LRQDEHTRRELAKMKQEPVRSEEGRDMANRISAFGYLECSAKTKEGVREVFEMATRAGLQ 180

Query: 181 ARRGKKKSGCLVL 193
            R+ K++ GC +L
Sbjct: 181 VRKNKRRRGCPIL 193


>gi|28395033 ras homolog gene family, member C precursor [Homo
           sapiens]
          Length = 193

 Score =  370 bits (949), Expect = e-103
 Identities = 177/193 (91%), Positives = 185/193 (95%)

Query: 1   MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDT 60
           MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENY+ADIEVDGKQVELALWDT
Sbjct: 1   MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYIADIEVDGKQVELALWDT 60

Query: 61  AGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKD 120
           AGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKD
Sbjct: 61  AGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKD 120

Query: 121 LRNDEHTRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDGVREVFEMATRAALQ 180
           LR DEHTRRELAKMKQEPV+ EEGRDMANRI AFGY+ECSAKTK+GVREVFEMATRA LQ
Sbjct: 121 LRQDEHTRRELAKMKQEPVRSEEGRDMANRISAFGYLECSAKTKEGVREVFEMATRAGLQ 180

Query: 181 ARRGKKKSGCLVL 193
            R+ K++ GC +L
Sbjct: 181 VRKNKRRRGCPIL 193


>gi|4757764 ras homolog gene family, member B [Homo sapiens]
          Length = 196

 Score =  337 bits (865), Expect = 3e-93
 Identities = 163/191 (85%), Positives = 177/191 (92%), Gaps = 1/191 (0%)

Query: 1   MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDT 60
           MAAIRKKLV+VGDGACGKTCLLIVFSKD+FPEVYVPTVFENYVADIEVDGKQVELALWDT
Sbjct: 1   MAAIRKKLVVVGDGACGKTCLLIVFSKDEFPEVYVPTVFENYVADIEVDGKQVELALWDT 60

Query: 61  AGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKD 120
           AGQEDYDRLRPLSYPDTDVILMCFS+DSPDSLENIPEKW PEVKHFCPNVPIILV NKKD
Sbjct: 61  AGQEDYDRLRPLSYPDTDVILMCFSVDSPDSLENIPEKWVPEVKHFCPNVPIILVANKKD 120

Query: 121 LRNDEHTRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDGVREVFEMATRAALQ 180
           LR+DEH R ELA+MKQEPV+ ++GR MA RI A+ Y+ECSAKTK+GVREVFE ATRAALQ
Sbjct: 121 LRSDEHVRTELARMKQEPVRTDDGRAMAVRIQAYDYLECSAKTKEGVREVFETATRAALQ 180

Query: 181 ARRGKKKSGCL 191
            R G  ++GC+
Sbjct: 181 KRYG-SQNGCI 190


>gi|9845511 ras-related C3 botulinum toxin substrate 1 isoform Rac1
           [Homo sapiens]
          Length = 192

 Score =  219 bits (558), Expect = 1e-57
 Identities = 110/188 (58%), Positives = 134/188 (71%), Gaps = 1/188 (0%)

Query: 7   KLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDY 66
           K V+VGDGA GKTCLLI ++ + FP  Y+PTVF+NY A++ VDGK V L LWDTAGQEDY
Sbjct: 5   KCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDY 64

Query: 67  DRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRNDEH 126
           DRLRPLSYP TDV L+CFS+ SP S EN+  KW PEV+H CPN PIILVG K DLR+D+ 
Sbjct: 65  DRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKD 124

Query: 127 TRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDGVREVFEMATRAALQARRGKK 186
           T  +L + K  P+   +G  MA  IGA  Y+ECSA T+ G++ VF+ A RA L     KK
Sbjct: 125 TIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCPPPVKK 184

Query: 187 -KSGCLVL 193
            K  CL+L
Sbjct: 185 RKRKCLLL 192


>gi|46249393 ras homolog gene family, member G [Homo sapiens]
          Length = 191

 Score =  216 bits (550), Expect = 1e-56
 Identities = 104/187 (55%), Positives = 132/187 (70%)

Query: 7   KLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDY 66
           K V+VGDGA GKTCLLI ++ + FP+ Y+PTVF+NY A   VDG+ V L LWDTAGQE+Y
Sbjct: 5   KCVVVGDGAVGKTCLLICYTTNAFPKEYIPTVFDNYSAQSAVDGRTVNLNLWDTAGQEEY 64

Query: 67  DRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRNDEH 126
           DRLR LSYP T+V ++CFSI SP S EN+  KW PEV H CP+VPI+LVG KKDLR    
Sbjct: 65  DRLRTLSYPQTNVFVICFSIASPPSYENVRHKWHPEVCHHCPDVPILLVGTKKDLRAQPD 124

Query: 127 TRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDGVREVFEMATRAALQARRGKK 186
           T R L +  Q P+ P++G+ +A +I A  Y+ECSA  +DGV+EVF  A RA L     K+
Sbjct: 125 TLRRLKEQGQAPITPQQGQALAKQIHAVRYLECSALQQDGVKEVFAEAVRAVLNPTPIKR 184

Query: 187 KSGCLVL 193
              C++L
Sbjct: 185 GRSCILL 191


>gi|89903012 cell division cycle 42 isoform 1 [Homo sapiens]
          Length = 191

 Score =  213 bits (542), Expect = 8e-56
 Identities = 100/187 (53%), Positives = 130/187 (69%)

Query: 7   KLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDY 66
           K V+VGDGA GKTCLLI ++ ++FP  YVPTVF+NY   + + G+   L L+DTAGQEDY
Sbjct: 5   KCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAGQEDY 64

Query: 67  DRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRNDEH 126
           DRLRPLSYP TDV L+CFS+ SP S EN+ EKW PE+ H CP  P +LVG + DLR+D  
Sbjct: 65  DRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCPKTPFLLVGTQIDLRDDPS 124

Query: 127 TRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDGVREVFEMATRAALQARRGKK 186
           T  +LAK KQ+P+ PE    +A  + A  Y+ECSA T+ G++ VF+ A  AAL+    KK
Sbjct: 125 TIEKLAKNKQKPITPETAEKLARDLKAVKYVECSALTQKGLKNVFDEAILAALEPPEPKK 184

Query: 187 KSGCLVL 193
              C++L
Sbjct: 185 SRRCVLL 191


>gi|4757952 cell division cycle 42 isoform 1 [Homo sapiens]
          Length = 191

 Score =  213 bits (542), Expect = 8e-56
 Identities = 100/187 (53%), Positives = 130/187 (69%)

Query: 7   KLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDY 66
           K V+VGDGA GKTCLLI ++ ++FP  YVPTVF+NY   + + G+   L L+DTAGQEDY
Sbjct: 5   KCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAGQEDY 64

Query: 67  DRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRNDEH 126
           DRLRPLSYP TDV L+CFS+ SP S EN+ EKW PE+ H CP  P +LVG + DLR+D  
Sbjct: 65  DRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCPKTPFLLVGTQIDLRDDPS 124

Query: 127 TRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDGVREVFEMATRAALQARRGKK 186
           T  +LAK KQ+P+ PE    +A  + A  Y+ECSA T+ G++ VF+ A  AAL+    KK
Sbjct: 125 TIEKLAKNKQKPITPETAEKLARDLKAVKYVECSALTQKGLKNVFDEAILAALEPPEPKK 184

Query: 187 KSGCLVL 193
              C++L
Sbjct: 185 SRRCVLL 191


>gi|4826962 ras-related C3 botulinum toxin substrate 3 (rho family,
           small GTP binding protein Rac3) [Homo sapiens]
          Length = 192

 Score =  211 bits (538), Expect = 2e-55
 Identities = 101/173 (58%), Positives = 125/173 (72%)

Query: 7   KLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDY 66
           K V+VGDGA GKTCLLI ++ + FP  Y+PTVF+NY A++ VDGK V L LWDTAGQEDY
Sbjct: 5   KCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDY 64

Query: 67  DRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRNDEH 126
           DRLRPLSYP TDV L+CFS+ SP S EN+  KW PEV+H CP+ PI+LVG K DLR+D+ 
Sbjct: 65  DRLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPHTPILLVGTKLDLRDDKD 124

Query: 127 TRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDGVREVFEMATRAAL 179
           T   L   K  P+   +G  MA  IG+  Y+ECSA T+ G++ VF+ A RA L
Sbjct: 125 TIERLRDKKLAPITYPQGLAMAREIGSVKYLECSALTQRGLKTVFDEAIRAVL 177


>gi|16357472 cell division cycle 42 isoform 2 [Homo sapiens]
          Length = 191

 Score =  209 bits (532), Expect = 1e-54
 Identities = 98/186 (52%), Positives = 128/186 (68%)

Query: 7   KLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDY 66
           K V+VGDGA GKTCLLI ++ ++FP  YVPTVF+NY   + + G+   L L+DTAGQEDY
Sbjct: 5   KCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAGQEDY 64

Query: 67  DRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRNDEH 126
           DRLRPLSYP TDV L+CFS+ SP S EN+ EKW PE+ H CP  P +LVG + DLR+D  
Sbjct: 65  DRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCPKTPFLLVGTQIDLRDDPS 124

Query: 127 TRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDGVREVFEMATRAALQARRGKK 186
           T  +LAK KQ+P+ PE    +A  + A  Y+ECSA T+ G++ VF+ A  AAL+    + 
Sbjct: 125 TIEKLAKNKQKPITPETAEKLARDLKAVKYVECSALTQRGLKNVFDEAILAALEPPETQP 184

Query: 187 KSGCLV 192
           K  C +
Sbjct: 185 KRKCCI 190


>gi|4506381 ras-related C3 botulinum toxin substrate 2 [Homo
           sapiens]
          Length = 192

 Score =  208 bits (529), Expect = 3e-54
 Identities = 103/188 (54%), Positives = 133/188 (70%), Gaps = 2/188 (1%)

Query: 7   KLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDY 66
           K V+VGDGA GKTCLLI ++ + FP  Y+PTVF+NY A++ VD K V L LWDTAGQEDY
Sbjct: 5   KCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDSKPVNLGLWDTAGQEDY 64

Query: 67  DRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRNDEH 126
           DRLRPLSYP TDV L+CFS+ SP S EN+  KW PEV+H CP+ PIILVG K DLR+D+ 
Sbjct: 65  DRLRPLSYPQTDVFLICFSLVSPASYENVRAKWFPEVRHHCPSTPIILVGTKLDLRDDKD 124

Query: 127 TRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDGVREVFEMATRAAL--QARRG 184
           T  +L + K  P+   +G  +A  I +  Y+ECSA T+ G++ VF+ A RA L  Q  R 
Sbjct: 125 TIEKLKEKKLAPITYPQGLALAKEIDSVKYLECSALTQRGLKTVFDEAIRAVLCPQPTRQ 184

Query: 185 KKKSGCLV 192
           +K++  L+
Sbjct: 185 QKRACSLL 192


>gi|9845509 ras-related C3 botulinum toxin substrate 1 isoform Rac1b
           [Homo sapiens]
          Length = 211

 Score =  207 bits (528), Expect = 3e-54
 Identities = 110/207 (53%), Positives = 134/207 (64%), Gaps = 20/207 (9%)

Query: 7   KLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDY 66
           K V+VGDGA GKTCLLI ++ + FP  Y+PTVF+NY A++ VDGK V L LWDTAGQEDY
Sbjct: 5   KCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDY 64

Query: 67  DRLRPLSYPDT-------------------DVILMCFSIDSPDSLENIPEKWTPEVKHFC 107
           DRLRPLSYP T                   DV L+CFS+ SP S EN+  KW PEV+H C
Sbjct: 65  DRLRPLSYPQTVGETYGKDITSRGKDKPIADVFLICFSLVSPASFENVRAKWYPEVRHHC 124

Query: 108 PNVPIILVGNKKDLRNDEHTRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDGV 167
           PN PIILVG K DLR+D+ T  +L + K  P+   +G  MA  IGA  Y+ECSA T+ G+
Sbjct: 125 PNTPIILVGTKLDLRDDKDTIEKLKEKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGL 184

Query: 168 REVFEMATRAALQARRGKK-KSGCLVL 193
           + VF+ A RA L     KK K  CL+L
Sbjct: 185 KTVFDEAIRAVLCPPPVKKRKRKCLLL 211


>gi|50263042 ras-like protein TC10 [Homo sapiens]
          Length = 205

 Score =  204 bits (520), Expect = 3e-53
 Identities = 99/189 (52%), Positives = 134/189 (70%), Gaps = 2/189 (1%)

Query: 3   AIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAG 62
           A+  K V+VGDGA GKTCLL+ ++ D FPE YVPTVF++Y   + V GKQ  L L+DTAG
Sbjct: 7   ALMLKCVVVGDGAVGKTCLLMSYANDAFPEEYVPTVFDHYAVSVTVGGKQYLLGLYDTAG 66

Query: 63  QEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLR 122
           QEDYDRLRPLSYP TDV L+CFS+ +P S +N+ E+W PE+K + PNVP +L+G + DLR
Sbjct: 67  QEDYDRLRPLSYPMTDVFLICFSVVNPASFQNVKEEWVPELKEYAPNVPFLLIGTQIDLR 126

Query: 123 NDEHTRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDGVREVFEMATRAALQAR 182
           +D  T   L  MK++P+  E+G+ +A  IGA  Y+ECSA T+ G++ VF+ A  A L  +
Sbjct: 127 DDPKTLARLNDMKEKPICVEQGQKLAKEIGACCYVECSALTQKGLKTVFDEAIIAILTPK 186

Query: 183 RG--KKKSG 189
           +   KK+ G
Sbjct: 187 KHTVKKRIG 195


>gi|7656900 ras homolog D [Homo sapiens]
          Length = 210

 Score =  204 bits (519), Expect = 4e-53
 Identities = 95/176 (53%), Positives = 122/176 (69%)

Query: 7   KLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDY 66
           K+V+VGDG CGKT LL+VF+   FPE Y PTVFE Y+ +++V GK V L +WDTAGQ+DY
Sbjct: 19  KVVLVGDGGCGKTSLLMVFADGAFPESYTPTVFERYMVNLQVKGKPVHLHIWDTAGQDDY 78

Query: 67  DRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRNDEH 126
           DRLRPL YPD  V+L+CF + SP+S +NI  +W PEV HFC  VPII+VG K DLR D+ 
Sbjct: 79  DRLRPLFYPDASVLLLCFDVTSPNSFDNIFNRWYPEVNHFCKKVPIIVVGCKTDLRKDKS 138

Query: 127 TRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDGVREVFEMATRAALQAR 182
              +L +   EPV    G++MA  +GA  Y+ECSA+  D V  VF+ A   AL +R
Sbjct: 139 LVNKLRRNGLEPVTYHRGQEMARSVGAVAYLECSARLHDNVHAVFQEAAEVALSSR 194


>gi|4885069 ras homolog gene family, member E [Homo sapiens]
          Length = 244

 Score =  198 bits (504), Expect = 2e-51
 Identities = 91/177 (51%), Positives = 131/177 (74%), Gaps = 1/177 (0%)

Query: 4   IRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQ 63
           ++ K+V+VGD  CGKT LL VF+KD FPE YVPTVFENY A  E+D +++EL+LWDT+G 
Sbjct: 22  VKCKIVVVGDSQCGKTALLHVFAKDCFPENYVPTVFENYTASFEIDTQRIELSLWDTSGS 81

Query: 64  EDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRN 123
             YD +RPLSYPD+D +L+CF I  P++L+++ +KW  E++ FCPN  ++LVG K DLR 
Sbjct: 82  PYYDNVRPLSYPDSDAVLICFDISRPETLDSVLKKWKGEIQEFCPNTKMLLVGCKSDLRT 141

Query: 124 DEHTRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSA-KTKDGVREVFEMATRAAL 179
           D  T  EL+  +Q PV  ++G +MA +IGA  Y+ECSA ++++ VR++F +AT A +
Sbjct: 142 DVSTLVELSNHRQTPVSYDQGANMAKQIGAATYIECSALQSENSVRDIFHVATLACV 198


>gi|4885581 Rho family GTPase 2 [Homo sapiens]
          Length = 227

 Score =  194 bits (494), Expect = 3e-50
 Identities = 93/198 (46%), Positives = 135/198 (68%), Gaps = 11/198 (5%)

Query: 5   RKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQE 64
           R K+V+VGD  CGKT LL VF+KD +P  YVPTVFENY A  E+D +++EL +WDT+G  
Sbjct: 7   RCKIVVVGDAECGKTALLQVFAKDAYPGSYVPTVFENYTASFEIDKRRIELNMWDTSGSS 66

Query: 65  DYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRND 124
            YD +RPL+YPD+D +L+CF I  P++L+++ +KW  E + FCPN  ++LVG K D+R D
Sbjct: 67  YYDNVRPLAYPDSDAVLICFDISRPETLDSVLKKWQGETQEFCPNAKVVLVGCKLDMRTD 126

Query: 125 EHTRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKD-GVREVFEMATRAAL---- 179
             T REL+K +  PV  E+G  +A ++GA  Y+ECS+++ +  VR+VF +AT A+L    
Sbjct: 127 LATLRELSKQRLIPVTHEQGTVLAKQVGAVSYVECSSRSSERSVRDVFHVATVASLGRGH 186

Query: 180 ------QARRGKKKSGCL 191
                  +RRG ++S  L
Sbjct: 187 RQLRRTDSRRGMQRSAQL 204


>gi|38016957 ras homolog gene family, member F [Homo sapiens]
          Length = 211

 Score =  192 bits (489), Expect = 1e-49
 Identities = 94/191 (49%), Positives = 130/191 (68%), Gaps = 4/191 (2%)

Query: 7   KLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDY 66
           K+VIVGDG CGKT LL+V+S+  FPE Y P+VFE Y A + V  K+V L L+DTAGQEDY
Sbjct: 21  KIVIVGDGGCGKTSLLMVYSQGSFPEHYAPSVFEKYTASVTVGSKEVTLNLYDTAGQEDY 80

Query: 67  DRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRNDEH 126
           DRLRPLSY +T ++L+C+ + +P S +N+  KW PEV HFC  +P++L+G K DLR D+ 
Sbjct: 81  DRLRPLSYQNTHLVLICYDVMNPTSYDNVLIKWFPEVTHFCRGIPMVLIGCKTDLRKDKE 140

Query: 127 TRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDGVREVFEMATRAAL----QAR 182
             R+L   + EP+   +G     +I A  Y+ECSAK ++ V +VF  A + AL    +A+
Sbjct: 141 QLRKLRAAQLEPITYMQGLSACEQIRAALYLECSAKFRENVEDVFREAAKVALSALKKAQ 200

Query: 183 RGKKKSGCLVL 193
           R KK+  CL+L
Sbjct: 201 RQKKRRLCLLL 211


>gi|16903164 ras homolog gene family, member J [Homo sapiens]
          Length = 214

 Score =  192 bits (489), Expect = 1e-49
 Identities = 92/181 (50%), Positives = 126/181 (69%)

Query: 7   KLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDY 66
           K V+VGDGA GKTCLL+ ++ D FPE YVPTVF++Y   + V GKQ  L L+DTAGQEDY
Sbjct: 23  KCVVVGDGAVGKTCLLMSYANDAFPEEYVPTVFDHYAVTVTVGGKQHLLGLYDTAGQEDY 82

Query: 67  DRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRNDEH 126
           ++LRPLSYP+TDV L+CFS+ +P S  N+ E+W PE+K   P+VP +L+G + DLR+D  
Sbjct: 83  NQLRPLSYPNTDVFLICFSVVNPASYHNVQEEWVPELKDCMPHVPYVLIGTQIDLRDDPK 142

Query: 127 TRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDGVREVFEMATRAALQARRGKK 186
           T   L  MK++P+  E G  +A  IGA  Y+ECSA T+ G++ VF+ A       ++ KK
Sbjct: 143 TLARLLYMKEKPLTYEHGVKLAKAIGAQCYLECSALTQKGLKAVFDEAILTIFHPKKKKK 202

Query: 187 K 187
           +
Sbjct: 203 R 203


>gi|11034843 ras homolog gene family, member U [Homo sapiens]
          Length = 258

 Score =  180 bits (456), Expect = 8e-46
 Identities = 84/174 (48%), Positives = 118/174 (67%)

Query: 7   KLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDY 66
           K V+VGDGA GKT L++ ++ + +P  Y+PT F+N+ A + VDG+ V L L DTAGQ+++
Sbjct: 51  KCVLVGDGAVGKTSLVVSYTTNGYPTEYIPTAFDNFSAVVSVDGRPVRLQLCDTAGQDEF 110

Query: 67  DRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRNDEH 126
           D+LRPL Y +TD+ L+CFS+ SP S +N+ EKW PE++  CP  PIILVG + DLR D  
Sbjct: 111 DKLRPLCYTNTDIFLLCFSVVSPSSFQNVSEKWVPEIRCHCPKAPIILVGTQSDLREDVK 170

Query: 127 TRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDGVREVFEMATRAALQ 180
              EL K K++PV  E  +  A  I A  Y+ECSA T+  ++EVF+ A  A +Q
Sbjct: 171 VLIELDKCKEKPVPEEAAKLCAEEIKAASYIECSALTQKNLKEVFDAAIVAGIQ 224


>gi|7657514 GTP-binding protein RHO6 [Homo sapiens]
          Length = 232

 Score =  167 bits (423), Expect = 5e-42
 Identities = 80/176 (45%), Positives = 117/176 (66%), Gaps = 1/176 (0%)

Query: 5   RKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQE 64
           R KLV+VGD  CGKT +L V +KD +PE YVPTVFENY A +E + ++VEL+LWDT+G  
Sbjct: 13  RCKLVLVGDVQCGKTAMLQVLAKDCYPETYVPTVFENYTACLETEEQRVELSLWDTSGSP 72

Query: 65  DYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRND 124
            YD +RPL Y D+D +L+CF I  P+++++  +KW  E+  +CP+  ++L+G K DLR D
Sbjct: 73  YYDNVRPLCYSDSDAVLLCFDISRPETVDSALKKWRTEILDYCPSTRVLLIGCKTDLRTD 132

Query: 125 EHTRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKD-GVREVFEMATRAAL 179
             T  EL+  KQ P+  E+G  +A ++GA  Y+E SA T +  +  +F  A+   L
Sbjct: 133 LSTLMELSHQKQAPISYEQGCAIAKQLGAEIYLEGSAFTSEKSIHSIFRTASMLCL 188


>gi|229577148 ras homolog gene family, member V [Homo sapiens]
          Length = 236

 Score =  162 bits (411), Expect = 1e-40
 Identities = 82/183 (44%), Positives = 119/183 (65%), Gaps = 3/183 (1%)

Query: 7   KLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDY 66
           K V+VGDGA GK+ L++ ++ + +P  Y PT  + +   + VDG  V + LWDTAGQED+
Sbjct: 33  KCVLVGDGAVGKSSLIVSYTCNGYPARYRPTALDTFSVQVLVDGAPVRIELWDTAGQEDF 92

Query: 67  DRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRNDEH 126
           DRLR L YPDTDV L CFS+  P S +NI EKW PE++   P  P++LVG + DLR+D +
Sbjct: 93  DRLRSLCYPDTDVFLACFSVVQPSSFQNITEKWLPEIRTHNPQAPVLLVGTQADLRDDVN 152

Query: 127 TRRELAKMKQE-PVKPEEGRDMANRIGAFGYMECSAKTKDGVREVFEMATRAALQ--ARR 183
              +L +  +E PV   + + +A +I A  Y+ECSA T+  ++EVF+ A  +A++  AR 
Sbjct: 153 VLIQLDQGGREGPVPQPQAQGLAEKIRACCYLECSALTQKNLKEVFDSAILSAIEHKARL 212

Query: 184 GKK 186
            KK
Sbjct: 213 EKK 215


>gi|4757770 ras homolog gene family, member H [Homo sapiens]
          Length = 191

 Score =  152 bits (385), Expect = 1e-37
 Identities = 77/182 (42%), Positives = 113/182 (62%), Gaps = 8/182 (4%)

Query: 7   KLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDY 66
           K V+VGD A GKT LL+ F+ + FPE Y PTV+EN   D+ +DG Q+ L LWDTAG + +
Sbjct: 6   KCVLVGDSAVGKTSLLVRFTSETFPEAYKPTVYENTGVDVFMDGIQISLGLWDTAGNDAF 65

Query: 67  DRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRNDEH 126
             +RPLSY   DV+LMC+S+ + +S  N+  KW  E++   P  P+++V  + D      
Sbjct: 66  RSIRPLSYQQADVVLMCYSVANHNSFLNLKNKWIGEIRSNLPCTPVLVVATQTD------ 119

Query: 127 TRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDGVREVFEMATRAAL-QARRGK 185
            +RE+   +   V   EG+ +A  + A GY+ECSA +  GV++VFE A R A+ QARR  
Sbjct: 120 -QREMGPHRASCVNAMEGKKLAQDVRAKGYLECSALSNRGVQQVFECAVRTAVNQARRRN 178

Query: 186 KK 187
           ++
Sbjct: 179 RR 180


>gi|237649113 Rho-related BTB domain containing 2 isoform 3 [Homo
           sapiens]
          Length = 727

 Score =  119 bits (298), Expect = 2e-27
 Identities = 78/200 (39%), Positives = 112/200 (56%), Gaps = 26/200 (13%)

Query: 7   KLVIVGDGACGKTCLLIV------FSKDQFPEVYVPTVF--ENYVADIEV--------DG 50
           K V+VGD A GKT L+         ++ Q    +VPTV+  + Y    EV        D 
Sbjct: 16  KCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVLERSRDVVDD 75

Query: 51  KQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNV 110
             V L LWDT G  D+ + R  +Y  +DV+++CFSI +P+SL ++   W PE+KHFCP  
Sbjct: 76  VSVSLRLWDTFG--DHHKDRRFAYGRSDVVVLCFSIANPNSLHHVKTMWYPEIKHFCPRA 133

Query: 111 PIILVGNKKDLRNDE-----HTRRELAK--MKQEPVKPEEGRDMANRIGAFGYMECSAKT 163
           P+ILVG + DLR  +       RR LA+     E + PE+GR++A  +G   Y E S   
Sbjct: 134 PVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKELG-IPYYETSVVA 192

Query: 164 KDGVREVFEMATRAALQARR 183
           + G+++VF+ A RAAL +RR
Sbjct: 193 QFGIKDVFDNAIRAALISRR 212


>gi|237649111 Rho-related BTB domain containing 2 isoform 2 [Homo
           sapiens]
          Length = 734

 Score =  119 bits (298), Expect = 2e-27
 Identities = 78/200 (39%), Positives = 112/200 (56%), Gaps = 26/200 (13%)

Query: 7   KLVIVGDGACGKTCLLIV------FSKDQFPEVYVPTVF--ENYVADIEV--------DG 50
           K V+VGD A GKT L+         ++ Q    +VPTV+  + Y    EV        D 
Sbjct: 23  KCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVLERSRDVVDD 82

Query: 51  KQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNV 110
             V L LWDT G  D+ + R  +Y  +DV+++CFSI +P+SL ++   W PE+KHFCP  
Sbjct: 83  VSVSLRLWDTFG--DHHKDRRFAYGRSDVVVLCFSIANPNSLHHVKTMWYPEIKHFCPRA 140

Query: 111 PIILVGNKKDLRNDE-----HTRRELAK--MKQEPVKPEEGRDMANRIGAFGYMECSAKT 163
           P+ILVG + DLR  +       RR LA+     E + PE+GR++A  +G   Y E S   
Sbjct: 141 PVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKELG-IPYYETSVVA 199

Query: 164 KDGVREVFEMATRAALQARR 183
           + G+++VF+ A RAAL +RR
Sbjct: 200 QFGIKDVFDNAIRAALISRR 219


>gi|237649109 Rho-related BTB domain containing 2 isoform 1 [Homo
           sapiens]
          Length = 749

 Score =  119 bits (298), Expect = 2e-27
 Identities = 78/200 (39%), Positives = 112/200 (56%), Gaps = 26/200 (13%)

Query: 7   KLVIVGDGACGKTCLLIV------FSKDQFPEVYVPTVF--ENYVADIEV--------DG 50
           K V+VGD A GKT L+         ++ Q    +VPTV+  + Y    EV        D 
Sbjct: 38  KCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVLERSRDVVDD 97

Query: 51  KQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNV 110
             V L LWDT G  D+ + R  +Y  +DV+++CFSI +P+SL ++   W PE+KHFCP  
Sbjct: 98  VSVSLRLWDTFG--DHHKDRRFAYGRSDVVVLCFSIANPNSLHHVKTMWYPEIKHFCPRA 155

Query: 111 PIILVGNKKDLRNDE-----HTRRELAK--MKQEPVKPEEGRDMANRIGAFGYMECSAKT 163
           P+ILVG + DLR  +       RR LA+     E + PE+GR++A  +G   Y E S   
Sbjct: 156 PVILVGCQLDLRYADLEAVNRARRPLARPIKPNEILPPEKGREVAKELG-IPYYETSVVA 214

Query: 164 KDGVREVFEMATRAALQARR 183
           + G+++VF+ A RAAL +RR
Sbjct: 215 QFGIKDVFDNAIRAALISRR 234


>gi|28629866 Rho-related BTB domain containing 1 [Homo sapiens]
          Length = 696

 Score =  117 bits (294), Expect = 5e-27
 Identities = 77/200 (38%), Positives = 113/200 (56%), Gaps = 26/200 (13%)

Query: 7   KLVIVGDGACGKTCLLIV------FSKDQFPEVYVPTVF--ENYVADIEV--------DG 50
           K V+VGD A GKT L+         ++ Q    +VPTV+  + Y    EV        D 
Sbjct: 16  KCVVVGDNAVGKTRLICARACNTTLTQYQLLATHVPTVWAIDQYRVCQEVLERSRDVVDE 75

Query: 51  KQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNV 110
             V L LWDT G  D+ + R  +Y  +DV+++CFSI +P+SL ++   W PE+KHFCP  
Sbjct: 76  VSVSLRLWDTFG--DHHKDRRFAYGRSDVVVLCFSIANPNSLNHVKSMWYPEIKHFCPRT 133

Query: 111 PIILVGNKKDLRNDE-----HTRRELAK--MKQEPVKPEEGRDMANRIGAFGYMECSAKT 163
           P+ILVG + DLR  +       RR LA+   + + + PE+GR++A  +G   Y E S   
Sbjct: 134 PVILVGCQLDLRYADLEAVNRARRPLARPIKRGDILPPEKGREVAKELG-LPYYETSVFD 192

Query: 164 KDGVREVFEMATRAALQARR 183
           + G+++VF+ A RAAL +RR
Sbjct: 193 QFGIKDVFDNAIRAALISRR 212


>gi|5803135 RAB35, member RAS oncogene family [Homo sapiens]
          Length = 201

 Score = 92.0 bits (227), Expect = 3e-19
 Identities = 56/178 (31%), Positives = 97/178 (54%), Gaps = 15/178 (8%)

Query: 7   KLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENY-VADIEVDGKQVELALWDTAGQED 65
           KL+I+GD   GK+ LL+ F+ + F   Y+ T+  ++ +  +E++G++V+L +WDTAGQE 
Sbjct: 10  KLLIIGDSGVGKSSLLLRFADNTFSGSYITTIGVDFKIRTVEINGEKVKLQIWDTAGQER 69

Query: 66  YDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRNDE 125
           +  +    Y  T  +++ + + S +S  N+ ++W  E+   C +V  ILVGNK    ND+
Sbjct: 70  FRTITSTYYRGTHGVIVVYDVTSAESFVNV-KRWLHEINQNCDDVCRILVGNK----NDD 124

Query: 126 HTRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDGVREVFEMATRAALQARR 183
             R+         V+ E+    A ++G     E SAK    V E+F   T   L+A++
Sbjct: 125 PERK--------VVETEDAYKFAGQMG-IQLFETSAKENVNVEEMFNCITELVLRAKK 173


>gi|21361418 RAB30, member RAS oncogene family [Homo sapiens]
          Length = 203

 Score = 91.7 bits (226), Expect = 4e-19
 Identities = 58/180 (32%), Positives = 101/180 (56%), Gaps = 17/180 (9%)

Query: 7   KLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENY-VADIEVDGKQVELALWDTAGQED 65
           K+V++G+   GKTCL+  F++  FP     T+  ++ +  +E++G++V+L +WDTAGQE 
Sbjct: 11  KIVLIGNAGVGKTCLVRRFTQGLFPPGQGATIGVDFMIKTVEINGEKVKLQIWDTAGQER 70

Query: 66  YDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPN-VPIILVGNKKDLRND 124
           +  +    Y   + +++ + I   +S   +PE W  E++ +  N V  +LVGNK DL   
Sbjct: 71  FRSITQSYYRSANALILTYDITCEESFRCLPE-WLREIEQYASNKVITVLVGNKIDLAE- 128

Query: 125 EHTRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDGVREVF-EMATRAALQARR 183
              RRE+++ + E     E +DM        Y+E SAK  D V ++F ++A R   +AR+
Sbjct: 129 ---RREVSQQRAEEF--SEAQDMY-------YLETSAKESDNVEKLFLDLACRLISEARQ 176


>gi|13569962 RAB1B, member RAS oncogene family [Homo sapiens]
          Length = 201

 Score = 90.5 bits (223), Expect = 8e-19
 Identities = 56/180 (31%), Positives = 94/180 (52%), Gaps = 17/180 (9%)

Query: 7   KLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENY-VADIEVDGKQVELALWDTAGQED 65
           KL+++GD   GK+CLL+ F+ D + E Y+ T+  ++ +  IE+DGK ++L +WDTAGQE 
Sbjct: 10  KLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQER 69

Query: 66  YDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFC-PNVPIILVGNKKDLRND 124
           +  +    Y     I++ + +   +S  N+ ++W  E+  +   NV  +LVGNK DL   
Sbjct: 70  FRTITSSYYRGAHGIIVVYDVTDQESYANV-KQWLQEIDRYASENVNKLLVGNKSDLTTK 128

Query: 125 EHTRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDGVREVFEMATRAALQARRG 184
           +      AK            + A+ +G   ++E SAK    V + F M   A ++ R G
Sbjct: 129 KVVDNTTAK------------EFADSLG-IPFLETSAKNATNVEQAF-MTMAAEIKKRMG 174


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.137    0.413 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,420,602
Number of Sequences: 37866
Number of extensions: 322978
Number of successful extensions: 1224
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 171
Number of HSP's successfully gapped in prelim test: 56
Number of HSP's that attempted gapping in prelim test: 835
Number of HSP's gapped (non-prelim): 230
length of query: 193
length of database: 18,247,518
effective HSP length: 97
effective length of query: 96
effective length of database: 14,574,516
effective search space: 1399153536
effective search space used: 1399153536
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.