Guide to the Human Genome
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Search of human proteins with 239582769

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239582769 hedgehog acyltransferase-like [Homo sapiens]
         (504 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239582769 hedgehog acyltransferase-like [Homo sapiens]            1031   0.0  
gi|170784861 hedgehog acyltransferase [Homo sapiens]                  182   6e-46
gi|170784863 hedgehog acyltransferase [Homo sapiens]                  182   6e-46
gi|46409316 zinc finger, DHHC-type containing 24 [Homo sapiens]        31   3.0  

>gi|239582769 hedgehog acyltransferase-like [Homo sapiens]
          Length = 504

 Score = 1031 bits (2665), Expect = 0.0
 Identities = 504/504 (100%), Positives = 504/504 (100%)

Query: 1   MGIKTALPAAELGLYSLVLSGALAYAGRGLLEASQDGAHRKAFRESVRPGWEYIGRKMDV 60
           MGIKTALPAAELGLYSLVLSGALAYAGRGLLEASQDGAHRKAFRESVRPGWEYIGRKMDV
Sbjct: 1   MGIKTALPAAELGLYSLVLSGALAYAGRGLLEASQDGAHRKAFRESVRPGWEYIGRKMDV 60

Query: 61  ADFEWVMWFTSFRNVIIFALSGHVLFAKLCTMVAPKLRSWMYAVYGALAVMGTMGPWYLL 120
           ADFEWVMWFTSFRNVIIFALSGHVLFAKLCTMVAPKLRSWMYAVYGALAVMGTMGPWYLL
Sbjct: 61  ADFEWVMWFTSFRNVIIFALSGHVLFAKLCTMVAPKLRSWMYAVYGALAVMGTMGPWYLL 120

Query: 121 LLLGHCVGLYVASLLGQPWLCLGLGLASLASFKMDPLISWQSGFVTGTFDLQEVLFHGGS 180
           LLLGHCVGLYVASLLGQPWLCLGLGLASLASFKMDPLISWQSGFVTGTFDLQEVLFHGGS
Sbjct: 121 LLLGHCVGLYVASLLGQPWLCLGLGLASLASFKMDPLISWQSGFVTGTFDLQEVLFHGGS 180

Query: 181 SFTVLRCTSFALESCAHPDRHYSLADLLKYNFYLPFFFFGPIMTFDRFHAQVSQVEPVRR 240
           SFTVLRCTSFALESCAHPDRHYSLADLLKYNFYLPFFFFGPIMTFDRFHAQVSQVEPVRR
Sbjct: 181 SFTVLRCTSFALESCAHPDRHYSLADLLKYNFYLPFFFFGPIMTFDRFHAQVSQVEPVRR 240

Query: 241 EGELWHIRAQAGLSVVAIMAVDIFFHFFYILTIPSDLKFANRLPDSALAGLAYSNLVYDW 300
           EGELWHIRAQAGLSVVAIMAVDIFFHFFYILTIPSDLKFANRLPDSALAGLAYSNLVYDW
Sbjct: 241 EGELWHIRAQAGLSVVAIMAVDIFFHFFYILTIPSDLKFANRLPDSALAGLAYSNLVYDW 300

Query: 301 VKAAVLFGVVNTVACLDHLDPPQPPKCITALYVFAETHFDRGINDWLCKYVYNHIGGEHS 360
           VKAAVLFGVVNTVACLDHLDPPQPPKCITALYVFAETHFDRGINDWLCKYVYNHIGGEHS
Sbjct: 301 VKAAVLFGVVNTVACLDHLDPPQPPKCITALYVFAETHFDRGINDWLCKYVYNHIGGEHS 360

Query: 361 AVIPELAATVATFAITTLWLGPCDIVYLWSFLNCFGLNFELWMQKLAEWGPLARIEASLS 420
           AVIPELAATVATFAITTLWLGPCDIVYLWSFLNCFGLNFELWMQKLAEWGPLARIEASLS
Sbjct: 361 AVIPELAATVATFAITTLWLGPCDIVYLWSFLNCFGLNFELWMQKLAEWGPLARIEASLS 420

Query: 421 VQMSRRVRALFGAMNFWAIIMYNLVSLNSLKFTELVARRLLLTGFPQTTLSILFVTYCGV 480
           VQMSRRVRALFGAMNFWAIIMYNLVSLNSLKFTELVARRLLLTGFPQTTLSILFVTYCGV
Sbjct: 421 VQMSRRVRALFGAMNFWAIIMYNLVSLNSLKFTELVARRLLLTGFPQTTLSILFVTYCGV 480

Query: 481 QLVKERERTLALEEEQKQDKEKPE 504
           QLVKERERTLALEEEQKQDKEKPE
Sbjct: 481 QLVKERERTLALEEEQKQDKEKPE 504


>gi|170784861 hedgehog acyltransferase [Homo sapiens]
          Length = 493

 Score =  182 bits (462), Expect = 6e-46
 Identities = 139/487 (28%), Positives = 225/487 (46%), Gaps = 25/487 (5%)

Query: 7   LPAAELGLYSLVLSGALAYAGRGLLEASQDGAHRKAFRESVRPGWEYIGRKMDVADFEWV 66
           LP  EL LY L   G   Y+   + + S++          +     + G K D  DFEW 
Sbjct: 2   LPRWELALYLLASLGFHFYSFYEVYKVSREHEEELDQEFELETDTLFGGLKKDATDFEWS 61

Query: 67  MWFTSFRNVIIFALSGHVLFAKLCTMVAPKLRSWMYAVYGALA---VMGTMGPWYLLL-- 121
            W    +  +++ L GH++ +++ T++A K R W+  +YG  A   V+GT G   +LL  
Sbjct: 62  FWMEWGKQWLVWLLLGHMVVSQMATLLARKHRPWILMLYGMWACWCVLGTPGVAMVLLHT 121

Query: 122 LLGHCVGLYVASLLGQPWLCLGLGLASLASFKMDPLISWQSGFVTGTFDLQEVLFHGGSS 181
            +  CV  + + LL   WLC  L L++L    ++ +           + LQ  L      
Sbjct: 122 TISFCVAQFRSQLL--TWLCSLLLLSTLRLQGVEEVKRRWYKTENEYYLLQFTL------ 173

Query: 182 FTVLRC---TSFALESCAHP----DRHYSLADLLKYNFYLPFFFFGPIMTFDRFHAQVSQ 234
              +RC   TSF+LE C          YS   +L Y FY P    GPI++F  F  Q+ Q
Sbjct: 174 --TVRCLYYTSFSLELCWQQLPAASTSYSFPWMLAYVFYYPVLHNGPILSFSEFIKQMQQ 231

Query: 235 VEPVRREGELWHIRAQAGLSVVAIMAVDIFFHFFYILTIPSDLKFANRLPDSALAGLAYS 294
            E    +  L  +    G  +      ++  H  Y+  I S +     +    L GLA +
Sbjct: 232 QEHDSLKASLCVLALGLGRLLCWWWLAELMAHLMYMHAIYSSIPLLETVSCWTLGGLALA 291

Query: 295 NLVYDWVKAAVLFGVVNTVACLDHLDPPQPPKCITALYVFAET--HFDRGINDWLCKYVY 352
            +++ +VK  VLFGV   +  LD L PP  P+C++ ++ F     +FD G++++L +YVY
Sbjct: 292 QVLFFYVKYLVLFGVPALLMRLDGLTPPALPRCVSTMFSFTGMWRYFDVGLHNFLIRYVY 351

Query: 353 NHIGGEHSAVIPELAATVATFAITTLWLGPCDIVYLWSFLNCFGLNFELWMQKLAEWGPL 412
             +GG    ++  L +T  TFA  + W G  D ++ W+ LN  G+  E  +++L E   +
Sbjct: 352 IPVGGSQHGLLGTLFSTAMTFAFVSYWHGGYDYLWCWAALNWLGVTVENGVRRLVETPCI 411

Query: 413 A-RIEASLSVQMSRRVRALFGAMNFWAIIMYNLVSLNSLKFTELVARRLLLTGFPQTTLS 471
              +    S Q  RR  A   + +   +I+ NLV L   +  +    R+ + G+P  TLS
Sbjct: 412 QDSLARYFSPQARRRFHAALASCSTSMLILSNLVFLGGNEVGKTYWNRIFIQGWPWVTLS 471

Query: 472 ILFVTYC 478
           +L   YC
Sbjct: 472 VLGFLYC 478


>gi|170784863 hedgehog acyltransferase [Homo sapiens]
          Length = 493

 Score =  182 bits (462), Expect = 6e-46
 Identities = 139/487 (28%), Positives = 225/487 (46%), Gaps = 25/487 (5%)

Query: 7   LPAAELGLYSLVLSGALAYAGRGLLEASQDGAHRKAFRESVRPGWEYIGRKMDVADFEWV 66
           LP  EL LY L   G   Y+   + + S++          +     + G K D  DFEW 
Sbjct: 2   LPRWELALYLLASLGFHFYSFYEVYKVSREHEEELDQEFELETDTLFGGLKKDATDFEWS 61

Query: 67  MWFTSFRNVIIFALSGHVLFAKLCTMVAPKLRSWMYAVYGALA---VMGTMGPWYLLL-- 121
            W    +  +++ L GH++ +++ T++A K R W+  +YG  A   V+GT G   +LL  
Sbjct: 62  FWMEWGKQWLVWLLLGHMVVSQMATLLARKHRPWILMLYGMWACWCVLGTPGVAMVLLHT 121

Query: 122 LLGHCVGLYVASLLGQPWLCLGLGLASLASFKMDPLISWQSGFVTGTFDLQEVLFHGGSS 181
            +  CV  + + LL   WLC  L L++L    ++ +           + LQ  L      
Sbjct: 122 TISFCVAQFRSQLL--TWLCSLLLLSTLRLQGVEEVKRRWYKTENEYYLLQFTL------ 173

Query: 182 FTVLRC---TSFALESCAHP----DRHYSLADLLKYNFYLPFFFFGPIMTFDRFHAQVSQ 234
              +RC   TSF+LE C          YS   +L Y FY P    GPI++F  F  Q+ Q
Sbjct: 174 --TVRCLYYTSFSLELCWQQLPAASTSYSFPWMLAYVFYYPVLHNGPILSFSEFIKQMQQ 231

Query: 235 VEPVRREGELWHIRAQAGLSVVAIMAVDIFFHFFYILTIPSDLKFANRLPDSALAGLAYS 294
            E    +  L  +    G  +      ++  H  Y+  I S +     +    L GLA +
Sbjct: 232 QEHDSLKASLCVLALGLGRLLCWWWLAELMAHLMYMHAIYSSIPLLETVSCWTLGGLALA 291

Query: 295 NLVYDWVKAAVLFGVVNTVACLDHLDPPQPPKCITALYVFAET--HFDRGINDWLCKYVY 352
            +++ +VK  VLFGV   +  LD L PP  P+C++ ++ F     +FD G++++L +YVY
Sbjct: 292 QVLFFYVKYLVLFGVPALLMRLDGLTPPALPRCVSTMFSFTGMWRYFDVGLHNFLIRYVY 351

Query: 353 NHIGGEHSAVIPELAATVATFAITTLWLGPCDIVYLWSFLNCFGLNFELWMQKLAEWGPL 412
             +GG    ++  L +T  TFA  + W G  D ++ W+ LN  G+  E  +++L E   +
Sbjct: 352 IPVGGSQHGLLGTLFSTAMTFAFVSYWHGGYDYLWCWAALNWLGVTVENGVRRLVETPCI 411

Query: 413 A-RIEASLSVQMSRRVRALFGAMNFWAIIMYNLVSLNSLKFTELVARRLLLTGFPQTTLS 471
              +    S Q  RR  A   + +   +I+ NLV L   +  +    R+ + G+P  TLS
Sbjct: 412 QDSLARYFSPQARRRFHAALASCSTSMLILSNLVFLGGNEVGKTYWNRIFIQGWPWVTLS 471

Query: 472 ILFVTYC 478
           +L   YC
Sbjct: 472 VLGFLYC 478


>gi|46409316 zinc finger, DHHC-type containing 24 [Homo sapiens]
          Length = 284

 Score = 30.8 bits (68), Expect = 3.0
 Identities = 23/60 (38%), Positives = 30/60 (50%), Gaps = 1/60 (1%)

Query: 95  PKLRSWMYAVYGALAVMGTMGPWYLLLLLGHCVGLYVASLLGQPWLCLGLGLASLASFKM 154
           P L   ++A    L V   +GP    LL  H   L++A+LL  PWL L  G  SLA F +
Sbjct: 138 PFLCLLLHAAGVLLHVSVLLGPALSALLRAH-TPLHMAALLLLPWLMLLTGRVSLAQFAL 196


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.328    0.140    0.453 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,391,426
Number of Sequences: 37866
Number of extensions: 766263
Number of successful extensions: 2236
Number of sequences better than 10.0: 4
Number of HSP's better than 10.0 without gapping: 3
Number of HSP's successfully gapped in prelim test: 1
Number of HSP's that attempted gapping in prelim test: 2221
Number of HSP's gapped (non-prelim): 4
length of query: 504
length of database: 18,247,518
effective HSP length: 107
effective length of query: 397
effective length of database: 14,195,856
effective search space: 5635754832
effective search space used: 5635754832
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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