Guide to the Human Genome
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Search of human proteins with 238908505

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|238908505 DNA-directed RNA polymerase III B isoform 2 [Homo
sapiens]
         (1075 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|238908505 DNA-directed RNA polymerase III B isoform 2 [Homo s...  2172   0.0  
gi|238908503 DNA-directed RNA polymerase III B isoform 1 [Homo s...  2172   0.0  
gi|4505941 DNA directed RNA polymerase II polypeptide B [Homo sa...   746   0.0  
gi|33469941 RNA polymerase I polypeptide B isoform 1 [Homo sapiens]   402   e-112
gi|212286172 RNA polymerase I polypeptide B isoform 2 [Homo sapi...   388   e-107
gi|20128768 serine/threonine kinase 35 [Homo sapiens]                  32   2.5  
gi|116063536 coenzyme Q5 homolog, methyltransferase [Homo sapiens]     31   5.5  
gi|123701326 zinc finger protein 831 [Homo sapiens]                    31   7.2  
gi|20357504 dystonin isoform 1eB precursor [Homo sapiens]              30   9.4  

>gi|238908505 DNA-directed RNA polymerase III B isoform 2 [Homo
            sapiens]
          Length = 1075

 Score = 2172 bits (5627), Expect = 0.0
 Identities = 1075/1075 (100%), Positives = 1075/1075 (100%)

Query: 1    MKANEKVTSDADPMWYLKYLNIYVGLPDVEESFNVTRPVSPHECRLRDMTYSAPITVDIE 60
            MKANEKVTSDADPMWYLKYLNIYVGLPDVEESFNVTRPVSPHECRLRDMTYSAPITVDIE
Sbjct: 1    MKANEKVTSDADPMWYLKYLNIYVGLPDVEESFNVTRPVSPHECRLRDMTYSAPITVDIE 60

Query: 61   YTRGSQRIIRNALPIGRMPIMLRSSNCVLTGKTPAEFAKLNECPLDPGGYFIVKGVEKVI 120
            YTRGSQRIIRNALPIGRMPIMLRSSNCVLTGKTPAEFAKLNECPLDPGGYFIVKGVEKVI
Sbjct: 61   YTRGSQRIIRNALPIGRMPIMLRSSNCVLTGKTPAEFAKLNECPLDPGGYFIVKGVEKVI 120

Query: 121  LIQEQLSKNRIIVEADRKGAVGASVTSSTHEKKSRTNMAVKQGRFYLRHNTLSEDIPIVI 180
            LIQEQLSKNRIIVEADRKGAVGASVTSSTHEKKSRTNMAVKQGRFYLRHNTLSEDIPIVI
Sbjct: 121  LIQEQLSKNRIIVEADRKGAVGASVTSSTHEKKSRTNMAVKQGRFYLRHNTLSEDIPIVI 180

Query: 181  IFKAMGVESDQEIVQMIGTEEHVMAAFGPSLEECQKAQIFTQMQALKYIGNKVRRQRMWG 240
            IFKAMGVESDQEIVQMIGTEEHVMAAFGPSLEECQKAQIFTQMQALKYIGNKVRRQRMWG
Sbjct: 181  IFKAMGVESDQEIVQMIGTEEHVMAAFGPSLEECQKAQIFTQMQALKYIGNKVRRQRMWG 240

Query: 241  GGPKKTKIEEARELLASTILTHVPVKEFNFRAKCIYTAVMVRRVILAQGDNKVDDRDYYG 300
            GGPKKTKIEEARELLASTILTHVPVKEFNFRAKCIYTAVMVRRVILAQGDNKVDDRDYYG
Sbjct: 241  GGPKKTKIEEARELLASTILTHVPVKEFNFRAKCIYTAVMVRRVILAQGDNKVDDRDYYG 300

Query: 301  NKRLELAGQLLSLLFEDLFKKFNSEMKKIADQVIPKQRAAQFDVVKHMRQDQITNGMVNA 360
            NKRLELAGQLLSLLFEDLFKKFNSEMKKIADQVIPKQRAAQFDVVKHMRQDQITNGMVNA
Sbjct: 301  NKRLELAGQLLSLLFEDLFKKFNSEMKKIADQVIPKQRAAQFDVVKHMRQDQITNGMVNA 360

Query: 361  ISTGNWSLKRFKMDRQGVTQVLSRLSYISALGMMTRISSQFEKTRKVSGPRSLQPSQWGM 420
            ISTGNWSLKRFKMDRQGVTQVLSRLSYISALGMMTRISSQFEKTRKVSGPRSLQPSQWGM
Sbjct: 361  ISTGNWSLKRFKMDRQGVTQVLSRLSYISALGMMTRISSQFEKTRKVSGPRSLQPSQWGM 420

Query: 421  LCPSDTPEGEACGLVKNLALMTHITTDMEDGPIVKLASNLGVEDVNLLCGEELSYPNVFL 480
            LCPSDTPEGEACGLVKNLALMTHITTDMEDGPIVKLASNLGVEDVNLLCGEELSYPNVFL
Sbjct: 421  LCPSDTPEGEACGLVKNLALMTHITTDMEDGPIVKLASNLGVEDVNLLCGEELSYPNVFL 480

Query: 481  VFLNGNILGVIRDHKKLVNTFRLMRRAGYINEFVSISTNLTDRCVYISSDGGRLCRPYII 540
            VFLNGNILGVIRDHKKLVNTFRLMRRAGYINEFVSISTNLTDRCVYISSDGGRLCRPYII
Sbjct: 481  VFLNGNILGVIRDHKKLVNTFRLMRRAGYINEFVSISTNLTDRCVYISSDGGRLCRPYII 540

Query: 541  VKKQKPAVTNKHMEELAQGYRNFEDFLHESLVEYLDVNEENDCNIALYEHTINKDTTHLE 600
            VKKQKPAVTNKHMEELAQGYRNFEDFLHESLVEYLDVNEENDCNIALYEHTINKDTTHLE
Sbjct: 541  VKKQKPAVTNKHMEELAQGYRNFEDFLHESLVEYLDVNEENDCNIALYEHTINKDTTHLE 600

Query: 601  IEPFTLLGVCAGLIPYPHHNQSPRNTYQCAMGKQAMGTIGYNQRNRIDTLMYLLAYPQKP 660
            IEPFTLLGVCAGLIPYPHHNQSPRNTYQCAMGKQAMGTIGYNQRNRIDTLMYLLAYPQKP
Sbjct: 601  IEPFTLLGVCAGLIPYPHHNQSPRNTYQCAMGKQAMGTIGYNQRNRIDTLMYLLAYPQKP 660

Query: 661  MVKTKTIELIEFEKLPAGQNATVAVMSYSGYDIEDALVLNKASLDRGFGRCLVYKNAKCT 720
            MVKTKTIELIEFEKLPAGQNATVAVMSYSGYDIEDALVLNKASLDRGFGRCLVYKNAKCT
Sbjct: 661  MVKTKTIELIEFEKLPAGQNATVAVMSYSGYDIEDALVLNKASLDRGFGRCLVYKNAKCT 720

Query: 721  LKRYTNQTFDKVMGPMLDAATRKPIWRHEILDADGICSPGEKVENKQVLVNKSMPTVTQI 780
            LKRYTNQTFDKVMGPMLDAATRKPIWRHEILDADGICSPGEKVENKQVLVNKSMPTVTQI
Sbjct: 721  LKRYTNQTFDKVMGPMLDAATRKPIWRHEILDADGICSPGEKVENKQVLVNKSMPTVTQI 780

Query: 781  PLEGSNVPQQPQYKDVPITYKGATDSYIEKVMISSNAEDAFLIKMLLRQTRRPEIGDKFS 840
            PLEGSNVPQQPQYKDVPITYKGATDSYIEKVMISSNAEDAFLIKMLLRQTRRPEIGDKFS
Sbjct: 781  PLEGSNVPQQPQYKDVPITYKGATDSYIEKVMISSNAEDAFLIKMLLRQTRRPEIGDKFS 840

Query: 841  SRHGQKGVCGLIVPQEDMPFCDSGICPDIIMNPHGFPSRMTVGKLIELLAGKAGVLDGRF 900
            SRHGQKGVCGLIVPQEDMPFCDSGICPDIIMNPHGFPSRMTVGKLIELLAGKAGVLDGRF
Sbjct: 841  SRHGQKGVCGLIVPQEDMPFCDSGICPDIIMNPHGFPSRMTVGKLIELLAGKAGVLDGRF 900

Query: 901  HYGTAFGGSKVKDVCEDLVRHGYNYLGKDYVTSGITGEPLEAYIYFGPVYYQKLKHMVLD 960
            HYGTAFGGSKVKDVCEDLVRHGYNYLGKDYVTSGITGEPLEAYIYFGPVYYQKLKHMVLD
Sbjct: 901  HYGTAFGGSKVKDVCEDLVRHGYNYLGKDYVTSGITGEPLEAYIYFGPVYYQKLKHMVLD 960

Query: 961  KMHARARGPRAVLTRQPTEGRSRDGGLRLGEMERDCLIGYGASMLLLERLMISSDAFEVD 1020
            KMHARARGPRAVLTRQPTEGRSRDGGLRLGEMERDCLIGYGASMLLLERLMISSDAFEVD
Sbjct: 961  KMHARARGPRAVLTRQPTEGRSRDGGLRLGEMERDCLIGYGASMLLLERLMISSDAFEVD 1020

Query: 1021 VCGQCGLLGYSGWCHYCKSSCHVSSLRIPYACKLLFQELQSMNIIPRLKLSKYNE 1075
            VCGQCGLLGYSGWCHYCKSSCHVSSLRIPYACKLLFQELQSMNIIPRLKLSKYNE
Sbjct: 1021 VCGQCGLLGYSGWCHYCKSSCHVSSLRIPYACKLLFQELQSMNIIPRLKLSKYNE 1075


>gi|238908503 DNA-directed RNA polymerase III B isoform 1 [Homo
            sapiens]
          Length = 1133

 Score = 2172 bits (5627), Expect = 0.0
 Identities = 1075/1075 (100%), Positives = 1075/1075 (100%)

Query: 1    MKANEKVTSDADPMWYLKYLNIYVGLPDVEESFNVTRPVSPHECRLRDMTYSAPITVDIE 60
            MKANEKVTSDADPMWYLKYLNIYVGLPDVEESFNVTRPVSPHECRLRDMTYSAPITVDIE
Sbjct: 59   MKANEKVTSDADPMWYLKYLNIYVGLPDVEESFNVTRPVSPHECRLRDMTYSAPITVDIE 118

Query: 61   YTRGSQRIIRNALPIGRMPIMLRSSNCVLTGKTPAEFAKLNECPLDPGGYFIVKGVEKVI 120
            YTRGSQRIIRNALPIGRMPIMLRSSNCVLTGKTPAEFAKLNECPLDPGGYFIVKGVEKVI
Sbjct: 119  YTRGSQRIIRNALPIGRMPIMLRSSNCVLTGKTPAEFAKLNECPLDPGGYFIVKGVEKVI 178

Query: 121  LIQEQLSKNRIIVEADRKGAVGASVTSSTHEKKSRTNMAVKQGRFYLRHNTLSEDIPIVI 180
            LIQEQLSKNRIIVEADRKGAVGASVTSSTHEKKSRTNMAVKQGRFYLRHNTLSEDIPIVI
Sbjct: 179  LIQEQLSKNRIIVEADRKGAVGASVTSSTHEKKSRTNMAVKQGRFYLRHNTLSEDIPIVI 238

Query: 181  IFKAMGVESDQEIVQMIGTEEHVMAAFGPSLEECQKAQIFTQMQALKYIGNKVRRQRMWG 240
            IFKAMGVESDQEIVQMIGTEEHVMAAFGPSLEECQKAQIFTQMQALKYIGNKVRRQRMWG
Sbjct: 239  IFKAMGVESDQEIVQMIGTEEHVMAAFGPSLEECQKAQIFTQMQALKYIGNKVRRQRMWG 298

Query: 241  GGPKKTKIEEARELLASTILTHVPVKEFNFRAKCIYTAVMVRRVILAQGDNKVDDRDYYG 300
            GGPKKTKIEEARELLASTILTHVPVKEFNFRAKCIYTAVMVRRVILAQGDNKVDDRDYYG
Sbjct: 299  GGPKKTKIEEARELLASTILTHVPVKEFNFRAKCIYTAVMVRRVILAQGDNKVDDRDYYG 358

Query: 301  NKRLELAGQLLSLLFEDLFKKFNSEMKKIADQVIPKQRAAQFDVVKHMRQDQITNGMVNA 360
            NKRLELAGQLLSLLFEDLFKKFNSEMKKIADQVIPKQRAAQFDVVKHMRQDQITNGMVNA
Sbjct: 359  NKRLELAGQLLSLLFEDLFKKFNSEMKKIADQVIPKQRAAQFDVVKHMRQDQITNGMVNA 418

Query: 361  ISTGNWSLKRFKMDRQGVTQVLSRLSYISALGMMTRISSQFEKTRKVSGPRSLQPSQWGM 420
            ISTGNWSLKRFKMDRQGVTQVLSRLSYISALGMMTRISSQFEKTRKVSGPRSLQPSQWGM
Sbjct: 419  ISTGNWSLKRFKMDRQGVTQVLSRLSYISALGMMTRISSQFEKTRKVSGPRSLQPSQWGM 478

Query: 421  LCPSDTPEGEACGLVKNLALMTHITTDMEDGPIVKLASNLGVEDVNLLCGEELSYPNVFL 480
            LCPSDTPEGEACGLVKNLALMTHITTDMEDGPIVKLASNLGVEDVNLLCGEELSYPNVFL
Sbjct: 479  LCPSDTPEGEACGLVKNLALMTHITTDMEDGPIVKLASNLGVEDVNLLCGEELSYPNVFL 538

Query: 481  VFLNGNILGVIRDHKKLVNTFRLMRRAGYINEFVSISTNLTDRCVYISSDGGRLCRPYII 540
            VFLNGNILGVIRDHKKLVNTFRLMRRAGYINEFVSISTNLTDRCVYISSDGGRLCRPYII
Sbjct: 539  VFLNGNILGVIRDHKKLVNTFRLMRRAGYINEFVSISTNLTDRCVYISSDGGRLCRPYII 598

Query: 541  VKKQKPAVTNKHMEELAQGYRNFEDFLHESLVEYLDVNEENDCNIALYEHTINKDTTHLE 600
            VKKQKPAVTNKHMEELAQGYRNFEDFLHESLVEYLDVNEENDCNIALYEHTINKDTTHLE
Sbjct: 599  VKKQKPAVTNKHMEELAQGYRNFEDFLHESLVEYLDVNEENDCNIALYEHTINKDTTHLE 658

Query: 601  IEPFTLLGVCAGLIPYPHHNQSPRNTYQCAMGKQAMGTIGYNQRNRIDTLMYLLAYPQKP 660
            IEPFTLLGVCAGLIPYPHHNQSPRNTYQCAMGKQAMGTIGYNQRNRIDTLMYLLAYPQKP
Sbjct: 659  IEPFTLLGVCAGLIPYPHHNQSPRNTYQCAMGKQAMGTIGYNQRNRIDTLMYLLAYPQKP 718

Query: 661  MVKTKTIELIEFEKLPAGQNATVAVMSYSGYDIEDALVLNKASLDRGFGRCLVYKNAKCT 720
            MVKTKTIELIEFEKLPAGQNATVAVMSYSGYDIEDALVLNKASLDRGFGRCLVYKNAKCT
Sbjct: 719  MVKTKTIELIEFEKLPAGQNATVAVMSYSGYDIEDALVLNKASLDRGFGRCLVYKNAKCT 778

Query: 721  LKRYTNQTFDKVMGPMLDAATRKPIWRHEILDADGICSPGEKVENKQVLVNKSMPTVTQI 780
            LKRYTNQTFDKVMGPMLDAATRKPIWRHEILDADGICSPGEKVENKQVLVNKSMPTVTQI
Sbjct: 779  LKRYTNQTFDKVMGPMLDAATRKPIWRHEILDADGICSPGEKVENKQVLVNKSMPTVTQI 838

Query: 781  PLEGSNVPQQPQYKDVPITYKGATDSYIEKVMISSNAEDAFLIKMLLRQTRRPEIGDKFS 840
            PLEGSNVPQQPQYKDVPITYKGATDSYIEKVMISSNAEDAFLIKMLLRQTRRPEIGDKFS
Sbjct: 839  PLEGSNVPQQPQYKDVPITYKGATDSYIEKVMISSNAEDAFLIKMLLRQTRRPEIGDKFS 898

Query: 841  SRHGQKGVCGLIVPQEDMPFCDSGICPDIIMNPHGFPSRMTVGKLIELLAGKAGVLDGRF 900
            SRHGQKGVCGLIVPQEDMPFCDSGICPDIIMNPHGFPSRMTVGKLIELLAGKAGVLDGRF
Sbjct: 899  SRHGQKGVCGLIVPQEDMPFCDSGICPDIIMNPHGFPSRMTVGKLIELLAGKAGVLDGRF 958

Query: 901  HYGTAFGGSKVKDVCEDLVRHGYNYLGKDYVTSGITGEPLEAYIYFGPVYYQKLKHMVLD 960
            HYGTAFGGSKVKDVCEDLVRHGYNYLGKDYVTSGITGEPLEAYIYFGPVYYQKLKHMVLD
Sbjct: 959  HYGTAFGGSKVKDVCEDLVRHGYNYLGKDYVTSGITGEPLEAYIYFGPVYYQKLKHMVLD 1018

Query: 961  KMHARARGPRAVLTRQPTEGRSRDGGLRLGEMERDCLIGYGASMLLLERLMISSDAFEVD 1020
            KMHARARGPRAVLTRQPTEGRSRDGGLRLGEMERDCLIGYGASMLLLERLMISSDAFEVD
Sbjct: 1019 KMHARARGPRAVLTRQPTEGRSRDGGLRLGEMERDCLIGYGASMLLLERLMISSDAFEVD 1078

Query: 1021 VCGQCGLLGYSGWCHYCKSSCHVSSLRIPYACKLLFQELQSMNIIPRLKLSKYNE 1075
            VCGQCGLLGYSGWCHYCKSSCHVSSLRIPYACKLLFQELQSMNIIPRLKLSKYNE
Sbjct: 1079 VCGQCGLLGYSGWCHYCKSSCHVSSLRIPYACKLLFQELQSMNIIPRLKLSKYNE 1133


>gi|4505941 DNA directed RNA polymerase II polypeptide B [Homo
            sapiens]
          Length = 1174

 Score =  746 bits (1925), Expect = 0.0
 Identities = 433/1106 (39%), Positives = 659/1106 (59%), Gaps = 66/1106 (5%)

Query: 13   PMWYLKYLNIYVGLPDVEESFNVTRPVSPHECRLRDMTYSAPITVDIEYT---RGSQRII 69
            P + LK+  IY+  P   E      P+ P+E RLR++TYSAP+ VDI  T    G +++ 
Sbjct: 82   PRYLLKFEQIYLSKPTHWERDGAPSPMMPNEARLRNLTYSAPLYVDITKTVIKEGEEQLQ 141

Query: 70   RNALP--IGRMPIMLRSSNCVLTGKTPAEFAKLNECPLDPGGYFIVKGVEKVILIQEQLS 127
                   IG++PIMLRS+ C+L G T  +  +LNECPLDPGGYFI+ G EKV++ QE+++
Sbjct: 142  TQHQKTFIGKIPIMLRSTYCLLNGLTDRDLCELNECPLDPGGYFIINGSEKVLIAQEKMA 201

Query: 128  KNRIIVEA--DRKGAVGASVTSSTHEKKSRTN-----MAVKQG----------RFYLRHN 170
             N + V A  D K A      S        T+     M  + G          R      
Sbjct: 202  TNTVYVFAKKDSKYAYTGECRSCLENSSRPTSTIWVSMLARGGQGAKKSAIGQRIVATLP 261

Query: 171  TLSEDIPIVIIFKAMGVESDQEIVQMI---GTEEHVMAAFGPSLEECQKAQIFTQMQALK 227
             + +++PI+I+F+A+G  SD++I++ I     +  +M    PSL+E    Q   Q  AL 
Sbjct: 262  YIKQEVPIIIVFRALGFVSDRDILEHIIYDFEDPEMMEMVKPSLDEAFVIQ--EQNVALN 319

Query: 228  YIGNKVRRQRMWGGGPKKTKIEEARELLASTILTHVPVKEFNFRAKCIYTAVMVRRVILA 287
            +IG++  +     G  K+ +I+ A+E+L   +L HV V +F    K  +   MV R++LA
Sbjct: 320  FIGSRGAKP----GVTKEKRIKYAKEVLQKEMLPHVGVSDFCETKKAYFLGYMVHRLLLA 375

Query: 288  Q-GDNKVDDRDYYGNKRLELAGQLLSLLFEDLFKKFNSEMKKIADQVIPKQRAAQFDVVK 346
              G  ++DDRD+YGNKRL+LAG LL+ LF  +FK    E++  A + I   R   F++  
Sbjct: 376  ALGRRELDDRDHYGNKRLDLAGPLLAFLFRGMFKNLLKEVRIYAQKFI--DRGKDFNLEL 433

Query: 347  HMRQDQITNGMVNAISTGNWS-LKRFKMDRQGVTQVLSRLSYISALGMMTRISSQFEKTR 405
             ++   I++G+  +++TGNW   K+    R GV+QVL+RL++ S L  + R++S   +  
Sbjct: 434  AIKTRIISDGLKYSLATGNWGDQKKAHQARAGVSQVLNRLTFASTLSHLRRLNSPIGRDG 493

Query: 406  KVSGPRSLQPSQWGMLCPSDTPEGEACGLVKNLALMTHITTDMEDGPIVKLASNLGVEDV 465
            K++ PR L  + WGM+CP++TPEG A GLVKNLALM +I+   +  PI++      +E++
Sbjct: 494  KLAKPRQLHNTLWGMVCPAETPEGHAVGLVKNLALMAYISVGSQPSPILEFLEEWSMENL 553

Query: 466  NLLCGEELSYPNVFLVFLNGNILGVIRDHKKLVNTFRLMRRA-GYINEFVSISTNLTDRC 524
              +    ++  +   +F+NG  +G+ +D ++L+NT R +RR    I   VS+  ++ +R 
Sbjct: 554  EEISPAAIA--DATKIFVNGCWVGIHKDPEQLMNTLRKLRRQMDIIVSEVSMIRDIRERE 611

Query: 525  VYISSDGGRLCRPYIIVKKQKPAVTNKHMEELAQG-YRNF--EDFLHESLVEYLDVNEEN 581
            + I +D GR+CRP +IV+KQK  +  +H+++L +  Y N+  +D +   +VEY+D  EE 
Sbjct: 612  IRIYTDAGRICRPLLIVEKQKLLLKKRHIDQLKEREYNNYSWQDLVASGVVEYIDTLEEE 671

Query: 582  DCNIALYEHTINKDT-------THLEIEPFTLLGVCAGLIPYPHHNQSPRNTYQCAMGKQ 634
               +A+    + +         TH EI P  +LGVCA +IP+P HNQSPRNTYQ AMGKQ
Sbjct: 672  TVMLAMTPDDLQEKEVAYCSTYTHCEIHPSMILGVCASIIPFPDHNQSPRNTYQSAMGKQ 731

Query: 635  AMGTIGYNQRNRIDTLMYLLAYPQKPMVKTKTIELIEFEKLPAGQNATVAVMSYSGYDIE 694
            AMG    N   R+DTL ++L YPQKP+V T+++E + F +LPAG N+ VA+ SY+GY+ E
Sbjct: 732  AMGVYITNFHVRMDTLAHVLYYPQKPLVTTRSMEYLRFRELPAGINSIVAIASYTGYNQE 791

Query: 695  DALVLNKASLDRGFGRCLVYKNAKCTLKRYTNQTFDKVMGPMLDAATRKPI--WRHEI-- 750
            D++++N++++DRGF R + Y++ K   ++ + + FD+    + +  TR+     RH I  
Sbjct: 792  DSVIMNRSAVDRGFFRSVFYRSYK---EQESKKGFDQ--EEVFEKPTRETCQGMRHAIYD 846

Query: 751  -LDADGICSPGEKVENKQVLVNKSMPTVTQIPLEGSNVPQQPQYKDVPITYKGATDSYIE 809
             LD DG+ +PG +V    V++ K++ T+ +   E  +  ++   +D     + +    ++
Sbjct: 847  KLDDDGLIAPGVRVSGDDVIIGKTV-TLPENEDELESTNRRYTKRDCSTFLRTSETGIVD 905

Query: 810  KVMISSNAEDAFLIKMLLRQTRRPEIGDKFSSRHGQKGVCGLIVPQEDMPFCDSGICPDI 869
            +VM++ N E     K+ +R  R P+IGDKF+SRHGQKG CG+   QEDMPF   GI PDI
Sbjct: 906  QVMVTLNQEGYKFCKIRVRSVRIPQIGDKFASRHGQKGTCGIQYRQEDMPFTCEGITPDI 965

Query: 870  IMNPHGFPSRMTVGKLIELLAGKAGVLDGRFHYGTAFGGS-KVKDVCEDLVRHGYNYLGK 928
            I+NPH  PSRMT+G LIE L GK     G     T F  +  V+ +   L  +GY+  G 
Sbjct: 966  IINPHAIPSRMTIGHLIECLQGKVSANKGEIGDATPFNDAVNVQKISNLLSDYGYHLRGN 1025

Query: 929  DYVTSGITGEPLEAYIYFGPVYYQKLKHMVLDKMHARARGPRAVLTRQPTEGRSRDGGLR 988
            + + +G TG  + + I+ GP YYQ+LKHMV DK+H+RARGP  +L RQP EGRSRDGGLR
Sbjct: 1026 EVLYNGFTGRKITSQIFIGPTYYQRLKHMVDDKIHSRARGPIQILNRQPMEGRSRDGGLR 1085

Query: 989  LGEMERDCLIGYGASMLLLERLMISSDAFEVDVCGQCGLLGYSGW------CHYCKSSCH 1042
             GEMERDC I +GA+  L ERL  +SD ++V VC  CG++  +        C  C++   
Sbjct: 1086 FGEMERDCQIAHGAAQFLRERLFEASDPYQVHVCNLCGIMAIANTRTHTYECRGCRNKTQ 1145

Query: 1043 VSSLRIPYACKLLFQELQSMNIIPRL 1068
            +S +R+PYACKLLFQEL SM+I PR+
Sbjct: 1146 ISLVRMPYACKLLFQELMSMSIAPRM 1171


>gi|33469941 RNA polymerase I polypeptide B isoform 1 [Homo sapiens]
          Length = 1135

 Score =  402 bits (1034), Expect = e-112
 Identities = 337/1093 (30%), Positives = 498/1093 (45%), Gaps = 121/1093 (11%)

Query: 39   VSPHECRLRDMTYSAPITVDIEYTRG--SQRIIRNALPIGRMPIMLRSSNCVLTGKTPAE 96
            V P ECR R  TY   +T DI +     S+ II+  L  G +PIM++S  C L    P  
Sbjct: 98   VYPAECRGRRSTYRGKLTADINWAVNGISKGIIKQFL--GYVPIMVKSKLCNLRNLPPQA 155

Query: 97   FAKLNECPLDPGGYFIVKGVEKVILIQEQLSKNRIIVEADRKGAV-GASVTS---STHEK 152
              + +E   + GGYFI+ G+EKVI +     +N  I     K    G   T    S H  
Sbjct: 156  LIEHHEEAEEMGGYFIINGIEKVIRMLIMPRRNFPIAMIRPKWKTRGPGYTQYGVSMHCV 215

Query: 153  KSRTNMAVKQGRFYLRHNTLSED---------IPIVIIFKAMGVESDQEIVQMI--GTEE 201
            +   + AV     YL + T+  +         +P+    KA+   SD +I Q +  G E+
Sbjct: 216  REE-HSAVNMNLHYLENGTVMLNFIYRKELFFLPLGFALKALVSFSDYQIFQELIKGKED 274

Query: 202  H--VMAAFGPSLEECQKAQIFTQMQALKYIGNKVRRQRMWGGGPKKTKIEEARELLAST- 258
               +  +    L    +    TQ Q L Y+G   R +      P     E+A E L +  
Sbjct: 275  DSFLRNSVSQMLRIVMEEGCSTQKQVLNYLGECFRVKL---NVPDWYPNEQAAEFLFNQC 331

Query: 259  ILTHVPVKEFNFRAKCIYTAVMVRRVILAQGDNKVDDRDYYGNKRLELAGQLLSLLFEDL 318
            I  H+      F   C+ T  +     LA+G+   D+ D   N+ +   GQL  +  ++ 
Sbjct: 332  ICIHLKSNTEKFYMLCLMTRKLFA---LAKGECMEDNPDSLVNQEVLTPGQLFLMFLKEK 388

Query: 319  FKKFNSEMKKIADQVIPKQRAAQFDVVKHMR----QDQITNGMVNAISTGNWSLKRFK-- 372
             + +   +K   D+   K  +   +    MR       +T       +TGN   K     
Sbjct: 389  LEGWLVSIKIAFDKKAQKT-SVSMNTDNLMRIFTMGIDLTKPFEYLFATGNLRSKTGLGL 447

Query: 373  MDRQGVTQVLSRLSYISALGMMTRI--SSQFEKTRKVSGPRSLQPSQWGMLCPSDTPEGE 430
            +   G+  V  +L++I  L     +   + F K R  +  R L P  WG LCP  TP+GE
Sbjct: 448  LQDSGLCVVADKLNFIRYLSHFRCVHRGADFAKMRTTT-VRRLLPESWGFLCPVHTPDGE 506

Query: 431  ACGLVKNLALMTHITTD-MEDGPIVKLASNLGVEDVNLLCGEELSYPNVFLVFLNGNILG 489
             CGL+ +L  +  + T  +    I  L  NLGV  ++       SY   + V L+G ++G
Sbjct: 507  PCGLMNHLTAVCEVVTQFVYTASIPALLCNLGVTPID--GAPHRSYSECYPVLLDGVMVG 564

Query: 490  VIRDH-----KKLVNTFRLMRRAGYINEFVSISTNLTDRC-----VYISSDGGRLCRPYI 539
             +           +  F+++R          +   +T +      +++ +   RL RP  
Sbjct: 565  WVDKDLAPGIADSLRHFKVLREKRIPPWMEVVLIPMTGKPSLYPGLFLFTTPCRLVRP-- 622

Query: 540  IVKKQKPAVTNKHMEELAQGYRNFEDFLHESLVEYLDVNEENDCNIALYEHTINKD-TTH 598
                         ++ LA G             E +   E+   N+A++E  +    TTH
Sbjct: 623  -------------VQNLALGKE-----------ELIGTMEQIFMNVAIFEDEVFAGVTTH 658

Query: 599  LEIEPFTLLGVCAGLIPYPHHNQSPRNTYQCAMGKQAMGTIGYNQRNRIDTLMYLLAYPQ 658
             E+ P +LL V A  IP+  HNQSPRN YQC MGKQ MG      ++R D  +Y L  PQ
Sbjct: 659  QELFPHSLLSVIANFIPFSDHNQSPRNMYQCQMGKQTMGFPLLTYQDRSDNKLYRLQTPQ 718

Query: 659  KPMVKTKTIELIEFEKLPAGQNATVAVMSYSGYDIEDALVLNKASLDRGFGRCLVYKNAK 718
             P+V+    +  + +  P G NA VAV+SY+GYD+EDA+++NKAS +RGF    VYK+  
Sbjct: 719  SPLVRPSMYDYYDMDNYPIGTNAIVAVISYTGYDMEDAMIVNKASWERGFAHGSVYKSEF 778

Query: 719  CTLKRYTNQTFDKVMGPMLDAATRKPIWRHEILDADGICSPGEKVENKQVLVNKSMPTVT 778
              L     Q    ++  +     R      + LD DG+   G K++          P  +
Sbjct: 779  IDLSEKIKQGDSSLVFGIKPGDPRVL----QKLDDDGLPFIGAKLQYGD-------PYYS 827

Query: 779  QIPLEGSNVPQQPQYKDVPITYKGATDSYIEKVMISSNAEDAFLIKML---LRQTRRPEI 835
             + L           +   + YK   +  ++ + + SN   +   K +   +R  R P I
Sbjct: 828  YLNLNTG--------ESFVMYYKSKENCVVDNIKVCSNDTGSGKFKCVCITMRVPRNPTI 879

Query: 836  GDKFSSRHGQKGVCGLIVPQEDMPFCDSGICPDIIMNPHGFPSRMTVGKLIELLAGKAGV 895
            GDKF+SRHGQKG+   + P EDMPF +SG+ PDI+ NPHGFPSRMT+G LIE +AGK+  
Sbjct: 880  GDKFASRHGQKGILSRLWPAEDMPFTESGMVPDILFNPHGFPSRMTIGMLIESMAGKSAA 939

Query: 896  LDGRFHYGTAF----GGSKVKDVCEDLVRHGYNYLGKDYVTSGITGEPLEAYIYFGPVYY 951
            L G  H  T F      S ++   E L   GYN+ G + + SGI+G  LEA I+ G VYY
Sbjct: 940  LHGLCHDATPFIFSEENSALEYFGEMLKAAGYNFYGTERLYSGISGLELEADIFIGVVYY 999

Query: 952  QKLKHMVLDKMHARARGPRAVLTRQPTEGRSRDGGLRLGEMERDCLIGYGASMLLLERLM 1011
            Q+L+HMV DK   R  G R  +T QP  GR+  GG+R GEMERD L+ +G S LL +RL 
Sbjct: 1000 QRLRHMVSDKFQVRTTGARDRVTNQPIGGRNVQGGIRFGEMERDALLAHGTSFLLHDRLF 1059

Query: 1012 ISSDAFEVDVCGQCGLL-------GYSGW---------CHYCKSSCHVSSLRIPYACKLL 1055
              SD     VC +CG L           W         C  C  S  + ++ +PY  +  
Sbjct: 1060 NCSDRSVAHVCVKCGSLLSPLLEKPPPSWSAMRNRKYNCTLCSRSDTIDTVSVPYVFRYF 1119

Query: 1056 FQELQSMNIIPRL 1068
              EL +MNI  +L
Sbjct: 1120 VAELAAMNIKVKL 1132


>gi|212286172 RNA polymerase I polypeptide B isoform 2 [Homo sapiens]
          Length = 1079

 Score =  388 bits (997), Expect = e-107
 Identities = 322/1055 (30%), Positives = 480/1055 (45%), Gaps = 117/1055 (11%)

Query: 75   IGRMPIMLRSSNCVLTGKTPAEFAKLNECPLDPGGYFIVKGVEKVILIQEQLSKNRIIVE 134
            +G +PIM++S  C L    P    + +E   + GGYFI+ G+EKVI +     +N  I  
Sbjct: 78   LGYVPIMVKSKLCNLRNLPPQALIEHHEEAEEMGGYFIINGIEKVIRMLIMPRRNFPIAM 137

Query: 135  ADRKGAV-GASVTS---STHEKKSRTNMAVKQGRFYLRHNTLSED---------IPIVII 181
               K    G   T    S H  +   + AV     YL + T+  +         +P+   
Sbjct: 138  IRPKWKTRGPGYTQYGVSMHCVREE-HSAVNMNLHYLENGTVMLNFIYRKELFFLPLGFA 196

Query: 182  FKAMGVESDQEIVQMI--GTEEH--VMAAFGPSLEECQKAQIFTQMQALKYIGNKVRRQR 237
             KA+   SD +I Q +  G E+   +  +    L    +    TQ Q L Y+G   R + 
Sbjct: 197  LKALVSFSDYQIFQELIKGKEDDSFLRNSVSQMLRIVMEEGCSTQKQVLNYLGECFRVKL 256

Query: 238  MWGGGPKKTKIEEARELLAST-ILTHVPVKEFNFRAKCIYTAVMVRRVILAQGDNKVDDR 296
                 P     E+A E L +  I  H+      F   C+ T  +     LA+G+   D+ 
Sbjct: 257  ---NVPDWYPNEQAAEFLFNQCICIHLKSNTEKFYMLCLMTRKLFA---LAKGECMEDNP 310

Query: 297  DYYGNKRLELAGQLLSLLFEDLFKKFNSEMKKIADQVIPKQRAAQFDVVKHMR----QDQ 352
            D   N+ +   GQL  +  ++  + +   +K   D+   K  +   +    MR       
Sbjct: 311  DSLVNQEVLTPGQLFLMFLKEKLEGWLVSIKIAFDKKAQKT-SVSMNTDNLMRIFTMGID 369

Query: 353  ITNGMVNAISTGNWSLKRFK--MDRQGVTQVLSRLSYISALGMMTRI--SSQFEKTRKVS 408
            +T       +TGN   K     +   G+  V  +L++I  L     +   + F K R  +
Sbjct: 370  LTKPFEYLFATGNLRSKTGLGLLQDSGLCVVADKLNFIRYLSHFRCVHRGADFAKMRTTT 429

Query: 409  GPRSLQPSQWGMLCPSDTPEGEACGLVKNLALMTHITTD-MEDGPIVKLASNLGVEDVNL 467
              R L P  WG LCP  TP+GE CGL+ +L  +  + T  +    I  L  NLGV  ++ 
Sbjct: 430  -VRRLLPESWGFLCPVHTPDGEPCGLMNHLTAVCEVVTQFVYTASIPALLCNLGVTPID- 487

Query: 468  LCGEELSYPNVFLVFLNGNILGVIRDH-----KKLVNTFRLMRRAGYINEFVSISTNLTD 522
                  SY   + V L+G ++G +           +  F+++R          +   +T 
Sbjct: 488  -GAPHRSYSECYPVLLDGVMVGWVDKDLAPGIADSLRHFKVLREKRIPPWMEVVLIPMTG 546

Query: 523  RC-----VYISSDGGRLCRPYIIVKKQKPAVTNKHMEELAQGYRNFEDFLHESLVEYLDV 577
            +      +++ +   RL RP               ++ LA G             E +  
Sbjct: 547  KPSLYPGLFLFTTPCRLVRP---------------VQNLALGKE-----------ELIGT 580

Query: 578  NEENDCNIALYEHTINKD-TTHLEIEPFTLLGVCAGLIPYPHHNQSPRNTYQCAMGKQAM 636
             E+   N+A++E  +    TTH E+ P +LL V A  IP+  HNQSPRN YQC MGKQ M
Sbjct: 581  MEQIFMNVAIFEDEVFAGVTTHQELFPHSLLSVIANFIPFSDHNQSPRNMYQCQMGKQTM 640

Query: 637  GTIGYNQRNRIDTLMYLLAYPQKPMVKTKTIELIEFEKLPAGQNATVAVMSYSGYDIEDA 696
            G      ++R D  +Y L  PQ P+V+    +  + +  P G NA VAV+SY+GYD+EDA
Sbjct: 641  GFPLLTYQDRSDNKLYRLQTPQSPLVRPSMYDYYDMDNYPIGTNAIVAVISYTGYDMEDA 700

Query: 697  LVLNKASLDRGFGRCLVYKNAKCTLKRYTNQTFDKVMGPMLDAATRKPIWRHEILDADGI 756
            +++NKAS +RGF    VYK+    L     Q    ++  +     R      + LD DG+
Sbjct: 701  MIVNKASWERGFAHGSVYKSEFIDLSEKIKQGDSSLVFGIKPGDPRVL----QKLDDDGL 756

Query: 757  CSPGEKVENKQVLVNKSMPTVTQIPLEGSNVPQQPQYKDVPITYKGATDSYIEKVMISSN 816
               G K++          P  + + L           +   + YK   +  ++ + + SN
Sbjct: 757  PFIGAKLQYGD-------PYYSYLNLNTG--------ESFVMYYKSKENCVVDNIKVCSN 801

Query: 817  AEDAFLIKML---LRQTRRPEIGDKFSSRHGQKGVCGLIVPQEDMPFCDSGICPDIIMNP 873
               +   K +   +R  R P IGDKF+SRHGQKG+   + P EDMPF +SG+ PDI+ NP
Sbjct: 802  DTGSGKFKCVCITMRVPRNPTIGDKFASRHGQKGILSRLWPAEDMPFTESGMVPDILFNP 861

Query: 874  HGFPSRMTVGKLIELLAGKAGVLDGRFHYGTAF----GGSKVKDVCEDLVRHGYNYLGKD 929
            HGFPSRMT+G LIE +AGK+  L G  H  T F      S ++   E L   GYN+ G +
Sbjct: 862  HGFPSRMTIGMLIESMAGKSAALHGLCHDATPFIFSEENSALEYFGEMLKAAGYNFYGTE 921

Query: 930  YVTSGITGEPLEAYIYFGPVYYQKLKHMVLDKMHARARGPRAVLTRQPTEGRSRDGGLRL 989
             + SGI+G  LEA I+ G VYYQ+L+HMV DK   R  G R  +T QP  GR+  GG+R 
Sbjct: 922  RLYSGISGLELEADIFIGVVYYQRLRHMVSDKFQVRTTGARDRVTNQPIGGRNVQGGIRF 981

Query: 990  GEMERDCLIGYGASMLLLERLMISSDAFEVDVCGQCGLL-------GYSGW--------- 1033
            GEMERD L+ +G S LL +RL   SD     VC +CG L           W         
Sbjct: 982  GEMERDALLAHGTSFLLHDRLFNCSDRSVAHVCVKCGSLLSPLLEKPPPSWSAMRNRKYN 1041

Query: 1034 CHYCKSSCHVSSLRIPYACKLLFQELQSMNIIPRL 1068
            C  C  S  + ++ +PY  +    EL +MNI  +L
Sbjct: 1042 CTLCSRSDTIDTVSVPYVFRYFVAELAAMNIKVKL 1076


>gi|20128768 serine/threonine kinase 35 [Homo sapiens]
          Length = 401

 Score = 32.3 bits (72), Expect = 2.5
 Identities = 25/86 (29%), Positives = 41/86 (47%), Gaps = 11/86 (12%)

Query: 530 DGGRLCRPYIIVKKQKPAVTNKHMEELAQGYRNFEDFLHESLVEYLDVNEENDCNIALYE 589
           +GG L   Y++ ++  PA     M +L         FLH++ + + D+  +N   I + E
Sbjct: 186 EGGDL-NQYVLSRRPDPATNKSFMLQLTSAIA----FLHKNHIVHRDLKPDN---ILITE 237

Query: 590 HTINKDTTHLEIEPFTLLGVCAGLIP 615
            +    T  L++  F L  VCAGL P
Sbjct: 238 RS---GTPILKVADFGLSKVCAGLAP 260


>gi|116063536 coenzyme Q5 homolog, methyltransferase [Homo sapiens]
          Length = 327

 Score = 31.2 bits (69), Expect = 5.5
 Identities = 17/39 (43%), Positives = 23/39 (58%)

Query: 542 KKQKPAVTNKHMEELAQGYRNFEDFLHESLVEYLDVNEE 580
           K+Q  A  N   EE+A+ Y+N ED L  S V   D+N+E
Sbjct: 137 KRQLRAQQNLSWEEIAKEYQNEEDSLGGSRVVVCDINKE 175


>gi|123701326 zinc finger protein 831 [Homo sapiens]
          Length = 1677

 Score = 30.8 bits (68), Expect = 7.2
 Identities = 23/79 (29%), Positives = 37/79 (46%), Gaps = 3/79 (3%)

Query: 812  MISSNAEDAFLIKMLLR--QTRRP-EIGDKFSSRHGQKGVCGLIVPQEDMPFCDSGICPD 868
            ++S+ A++AF  K LLR  Q   P  +   +  RH Q  +C    P+E   F  SG+   
Sbjct: 928  VLSALADNAFSPKYLLRLPQAETPLPLPIPWGPRHSQDSLCSSGWPEERASFVGSGLGTP 987

Query: 869  IIMNPHGFPSRMTVGKLIE 887
            +  +P   PS      ++E
Sbjct: 988  LSPSPASGPSPGEADSILE 1006


>gi|20357504 dystonin isoform 1eB precursor [Homo sapiens]
          Length = 3062

 Score = 30.4 bits (67), Expect = 9.4
 Identities = 21/87 (24%), Positives = 35/87 (40%)

Query: 377  GVTQVLSRLSYISALGMMTRISSQFEKTRKVSGPRSLQPSQWGMLCPSDTPEGEACGLVK 436
            G T +   L  +S+ G+    +S  EK    + P S      G     +TPE   C + +
Sbjct: 1706 GNTAIKECLDVLSSSGVFLNNASGREKDECTATPSSFNKCHCGEPEHEETPENRKCAIDE 1765

Query: 437  NLALMTHITTDMEDGPIVKLASNLGVE 463
                M +   + E     KLAS + ++
Sbjct: 1766 EFNEMRNTVINSEFSQSGKLASTISID 1792


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.137    0.406 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 39,549,304
Number of Sequences: 37866
Number of extensions: 1779663
Number of successful extensions: 3496
Number of sequences better than 10.0: 9
Number of HSP's better than 10.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 3463
Number of HSP's gapped (non-prelim): 14
length of query: 1075
length of database: 18,247,518
effective HSP length: 113
effective length of query: 962
effective length of database: 13,968,660
effective search space: 13437850920
effective search space used: 13437850920
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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