Search of human proteins with 238908503

Search of human proteins with 238908503

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|238908503 DNA-directed RNA polymerase III B isoform 1 [Homo
sapiens]
         (1133 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|238908503 DNA-directed RNA polymerase III B isoform 1 [Homo s...  2286   0.0  
gi|238908505 DNA-directed RNA polymerase III B isoform 2 [Homo s...  2172   0.0  
gi|4505941 DNA directed RNA polymerase II polypeptide B [Homo sa...   767   0.0  
gi|33469941 RNA polymerase I polypeptide B isoform 1 [Homo sapiens]   406   e-113
gi|212286172 RNA polymerase I polypeptide B isoform 2 [Homo sapi...   388   e-107
gi|20128768 serine/threonine kinase 35 [Homo sapiens]                  32   2.6  
gi|116063536 coenzyme Q5 homolog, methyltransferase [Homo sapiens]     31   5.8  
gi|123701326 zinc finger protein 831 [Homo sapiens]                    31   7.6  
gi|20357504 dystonin isoform 1eB precursor [Homo sapiens]              30   9.9  

>gi|238908503 DNA-directed RNA polymerase III B isoform 1 [Homo
            sapiens]
          Length = 1133

 Score = 2286 bits (5925), Expect = 0.0
 Identities = 1133/1133 (100%), Positives = 1133/1133 (100%)

Query: 1    MDVLAEEFGNLTPEQLAAPIPTVEEKWRLLPAFLKVKGLVKQHIDSFNYFINVEIKKIMK 60
            MDVLAEEFGNLTPEQLAAPIPTVEEKWRLLPAFLKVKGLVKQHIDSFNYFINVEIKKIMK
Sbjct: 1    MDVLAEEFGNLTPEQLAAPIPTVEEKWRLLPAFLKVKGLVKQHIDSFNYFINVEIKKIMK 60

Query: 61   ANEKVTSDADPMWYLKYLNIYVGLPDVEESFNVTRPVSPHECRLRDMTYSAPITVDIEYT 120
            ANEKVTSDADPMWYLKYLNIYVGLPDVEESFNVTRPVSPHECRLRDMTYSAPITVDIEYT
Sbjct: 61   ANEKVTSDADPMWYLKYLNIYVGLPDVEESFNVTRPVSPHECRLRDMTYSAPITVDIEYT 120

Query: 121  RGSQRIIRNALPIGRMPIMLRSSNCVLTGKTPAEFAKLNECPLDPGGYFIVKGVEKVILI 180
            RGSQRIIRNALPIGRMPIMLRSSNCVLTGKTPAEFAKLNECPLDPGGYFIVKGVEKVILI
Sbjct: 121  RGSQRIIRNALPIGRMPIMLRSSNCVLTGKTPAEFAKLNECPLDPGGYFIVKGVEKVILI 180

Query: 181  QEQLSKNRIIVEADRKGAVGASVTSSTHEKKSRTNMAVKQGRFYLRHNTLSEDIPIVIIF 240
            QEQLSKNRIIVEADRKGAVGASVTSSTHEKKSRTNMAVKQGRFYLRHNTLSEDIPIVIIF
Sbjct: 181  QEQLSKNRIIVEADRKGAVGASVTSSTHEKKSRTNMAVKQGRFYLRHNTLSEDIPIVIIF 240

Query: 241  KAMGVESDQEIVQMIGTEEHVMAAFGPSLEECQKAQIFTQMQALKYIGNKVRRQRMWGGG 300
            KAMGVESDQEIVQMIGTEEHVMAAFGPSLEECQKAQIFTQMQALKYIGNKVRRQRMWGGG
Sbjct: 241  KAMGVESDQEIVQMIGTEEHVMAAFGPSLEECQKAQIFTQMQALKYIGNKVRRQRMWGGG 300

Query: 301  PKKTKIEEARELLASTILTHVPVKEFNFRAKCIYTAVMVRRVILAQGDNKVDDRDYYGNK 360
            PKKTKIEEARELLASTILTHVPVKEFNFRAKCIYTAVMVRRVILAQGDNKVDDRDYYGNK
Sbjct: 301  PKKTKIEEARELLASTILTHVPVKEFNFRAKCIYTAVMVRRVILAQGDNKVDDRDYYGNK 360

Query: 361  RLELAGQLLSLLFEDLFKKFNSEMKKIADQVIPKQRAAQFDVVKHMRQDQITNGMVNAIS 420
            RLELAGQLLSLLFEDLFKKFNSEMKKIADQVIPKQRAAQFDVVKHMRQDQITNGMVNAIS
Sbjct: 361  RLELAGQLLSLLFEDLFKKFNSEMKKIADQVIPKQRAAQFDVVKHMRQDQITNGMVNAIS 420

Query: 421  TGNWSLKRFKMDRQGVTQVLSRLSYISALGMMTRISSQFEKTRKVSGPRSLQPSQWGMLC 480
            TGNWSLKRFKMDRQGVTQVLSRLSYISALGMMTRISSQFEKTRKVSGPRSLQPSQWGMLC
Sbjct: 421  TGNWSLKRFKMDRQGVTQVLSRLSYISALGMMTRISSQFEKTRKVSGPRSLQPSQWGMLC 480

Query: 481  PSDTPEGEACGLVKNLALMTHITTDMEDGPIVKLASNLGVEDVNLLCGEELSYPNVFLVF 540
            PSDTPEGEACGLVKNLALMTHITTDMEDGPIVKLASNLGVEDVNLLCGEELSYPNVFLVF
Sbjct: 481  PSDTPEGEACGLVKNLALMTHITTDMEDGPIVKLASNLGVEDVNLLCGEELSYPNVFLVF 540

Query: 541  LNGNILGVIRDHKKLVNTFRLMRRAGYINEFVSISTNLTDRCVYISSDGGRLCRPYIIVK 600
            LNGNILGVIRDHKKLVNTFRLMRRAGYINEFVSISTNLTDRCVYISSDGGRLCRPYIIVK
Sbjct: 541  LNGNILGVIRDHKKLVNTFRLMRRAGYINEFVSISTNLTDRCVYISSDGGRLCRPYIIVK 600

Query: 601  KQKPAVTNKHMEELAQGYRNFEDFLHESLVEYLDVNEENDCNIALYEHTINKDTTHLEIE 660
            KQKPAVTNKHMEELAQGYRNFEDFLHESLVEYLDVNEENDCNIALYEHTINKDTTHLEIE
Sbjct: 601  KQKPAVTNKHMEELAQGYRNFEDFLHESLVEYLDVNEENDCNIALYEHTINKDTTHLEIE 660

Query: 661  PFTLLGVCAGLIPYPHHNQSPRNTYQCAMGKQAMGTIGYNQRNRIDTLMYLLAYPQKPMV 720
            PFTLLGVCAGLIPYPHHNQSPRNTYQCAMGKQAMGTIGYNQRNRIDTLMYLLAYPQKPMV
Sbjct: 661  PFTLLGVCAGLIPYPHHNQSPRNTYQCAMGKQAMGTIGYNQRNRIDTLMYLLAYPQKPMV 720

Query: 721  KTKTIELIEFEKLPAGQNATVAVMSYSGYDIEDALVLNKASLDRGFGRCLVYKNAKCTLK 780
            KTKTIELIEFEKLPAGQNATVAVMSYSGYDIEDALVLNKASLDRGFGRCLVYKNAKCTLK
Sbjct: 721  KTKTIELIEFEKLPAGQNATVAVMSYSGYDIEDALVLNKASLDRGFGRCLVYKNAKCTLK 780

Query: 781  RYTNQTFDKVMGPMLDAATRKPIWRHEILDADGICSPGEKVENKQVLVNKSMPTVTQIPL 840
            RYTNQTFDKVMGPMLDAATRKPIWRHEILDADGICSPGEKVENKQVLVNKSMPTVTQIPL
Sbjct: 781  RYTNQTFDKVMGPMLDAATRKPIWRHEILDADGICSPGEKVENKQVLVNKSMPTVTQIPL 840

Query: 841  EGSNVPQQPQYKDVPITYKGATDSYIEKVMISSNAEDAFLIKMLLRQTRRPEIGDKFSSR 900
            EGSNVPQQPQYKDVPITYKGATDSYIEKVMISSNAEDAFLIKMLLRQTRRPEIGDKFSSR
Sbjct: 841  EGSNVPQQPQYKDVPITYKGATDSYIEKVMISSNAEDAFLIKMLLRQTRRPEIGDKFSSR 900

Query: 901  HGQKGVCGLIVPQEDMPFCDSGICPDIIMNPHGFPSRMTVGKLIELLAGKAGVLDGRFHY 960
            HGQKGVCGLIVPQEDMPFCDSGICPDIIMNPHGFPSRMTVGKLIELLAGKAGVLDGRFHY
Sbjct: 901  HGQKGVCGLIVPQEDMPFCDSGICPDIIMNPHGFPSRMTVGKLIELLAGKAGVLDGRFHY 960

Query: 961  GTAFGGSKVKDVCEDLVRHGYNYLGKDYVTSGITGEPLEAYIYFGPVYYQKLKHMVLDKM 1020
            GTAFGGSKVKDVCEDLVRHGYNYLGKDYVTSGITGEPLEAYIYFGPVYYQKLKHMVLDKM
Sbjct: 961  GTAFGGSKVKDVCEDLVRHGYNYLGKDYVTSGITGEPLEAYIYFGPVYYQKLKHMVLDKM 1020

Query: 1021 HARARGPRAVLTRQPTEGRSRDGGLRLGEMERDCLIGYGASMLLLERLMISSDAFEVDVC 1080
            HARARGPRAVLTRQPTEGRSRDGGLRLGEMERDCLIGYGASMLLLERLMISSDAFEVDVC
Sbjct: 1021 HARARGPRAVLTRQPTEGRSRDGGLRLGEMERDCLIGYGASMLLLERLMISSDAFEVDVC 1080

Query: 1081 GQCGLLGYSGWCHYCKSSCHVSSLRIPYACKLLFQELQSMNIIPRLKLSKYNE 1133
            GQCGLLGYSGWCHYCKSSCHVSSLRIPYACKLLFQELQSMNIIPRLKLSKYNE
Sbjct: 1081 GQCGLLGYSGWCHYCKSSCHVSSLRIPYACKLLFQELQSMNIIPRLKLSKYNE 1133


>gi|238908505 DNA-directed RNA polymerase III B isoform 2 [Homo
            sapiens]
          Length = 1075

 Score = 2172 bits (5627), Expect = 0.0
 Identities = 1075/1075 (100%), Positives = 1075/1075 (100%)

Query: 59   MKANEKVTSDADPMWYLKYLNIYVGLPDVEESFNVTRPVSPHECRLRDMTYSAPITVDIE 118
            MKANEKVTSDADPMWYLKYLNIYVGLPDVEESFNVTRPVSPHECRLRDMTYSAPITVDIE
Sbjct: 1    MKANEKVTSDADPMWYLKYLNIYVGLPDVEESFNVTRPVSPHECRLRDMTYSAPITVDIE 60

Query: 119  YTRGSQRIIRNALPIGRMPIMLRSSNCVLTGKTPAEFAKLNECPLDPGGYFIVKGVEKVI 178
            YTRGSQRIIRNALPIGRMPIMLRSSNCVLTGKTPAEFAKLNECPLDPGGYFIVKGVEKVI
Sbjct: 61   YTRGSQRIIRNALPIGRMPIMLRSSNCVLTGKTPAEFAKLNECPLDPGGYFIVKGVEKVI 120

Query: 179  LIQEQLSKNRIIVEADRKGAVGASVTSSTHEKKSRTNMAVKQGRFYLRHNTLSEDIPIVI 238
            LIQEQLSKNRIIVEADRKGAVGASVTSSTHEKKSRTNMAVKQGRFYLRHNTLSEDIPIVI
Sbjct: 121  LIQEQLSKNRIIVEADRKGAVGASVTSSTHEKKSRTNMAVKQGRFYLRHNTLSEDIPIVI 180

Query: 239  IFKAMGVESDQEIVQMIGTEEHVMAAFGPSLEECQKAQIFTQMQALKYIGNKVRRQRMWG 298
            IFKAMGVESDQEIVQMIGTEEHVMAAFGPSLEECQKAQIFTQMQALKYIGNKVRRQRMWG
Sbjct: 181  IFKAMGVESDQEIVQMIGTEEHVMAAFGPSLEECQKAQIFTQMQALKYIGNKVRRQRMWG 240

Query: 299  GGPKKTKIEEARELLASTILTHVPVKEFNFRAKCIYTAVMVRRVILAQGDNKVDDRDYYG 358
            GGPKKTKIEEARELLASTILTHVPVKEFNFRAKCIYTAVMVRRVILAQGDNKVDDRDYYG
Sbjct: 241  GGPKKTKIEEARELLASTILTHVPVKEFNFRAKCIYTAVMVRRVILAQGDNKVDDRDYYG 300

Query: 359  NKRLELAGQLLSLLFEDLFKKFNSEMKKIADQVIPKQRAAQFDVVKHMRQDQITNGMVNA 418
            NKRLELAGQLLSLLFEDLFKKFNSEMKKIADQVIPKQRAAQFDVVKHMRQDQITNGMVNA
Sbjct: 301  NKRLELAGQLLSLLFEDLFKKFNSEMKKIADQVIPKQRAAQFDVVKHMRQDQITNGMVNA 360

Query: 419  ISTGNWSLKRFKMDRQGVTQVLSRLSYISALGMMTRISSQFEKTRKVSGPRSLQPSQWGM 478
            ISTGNWSLKRFKMDRQGVTQVLSRLSYISALGMMTRISSQFEKTRKVSGPRSLQPSQWGM
Sbjct: 361  ISTGNWSLKRFKMDRQGVTQVLSRLSYISALGMMTRISSQFEKTRKVSGPRSLQPSQWGM 420

Query: 479  LCPSDTPEGEACGLVKNLALMTHITTDMEDGPIVKLASNLGVEDVNLLCGEELSYPNVFL 538
            LCPSDTPEGEACGLVKNLALMTHITTDMEDGPIVKLASNLGVEDVNLLCGEELSYPNVFL
Sbjct: 421  LCPSDTPEGEACGLVKNLALMTHITTDMEDGPIVKLASNLGVEDVNLLCGEELSYPNVFL 480

Query: 539  VFLNGNILGVIRDHKKLVNTFRLMRRAGYINEFVSISTNLTDRCVYISSDGGRLCRPYII 598
            VFLNGNILGVIRDHKKLVNTFRLMRRAGYINEFVSISTNLTDRCVYISSDGGRLCRPYII
Sbjct: 481  VFLNGNILGVIRDHKKLVNTFRLMRRAGYINEFVSISTNLTDRCVYISSDGGRLCRPYII 540

Query: 599  VKKQKPAVTNKHMEELAQGYRNFEDFLHESLVEYLDVNEENDCNIALYEHTINKDTTHLE 658
            VKKQKPAVTNKHMEELAQGYRNFEDFLHESLVEYLDVNEENDCNIALYEHTINKDTTHLE
Sbjct: 541  VKKQKPAVTNKHMEELAQGYRNFEDFLHESLVEYLDVNEENDCNIALYEHTINKDTTHLE 600

Query: 659  IEPFTLLGVCAGLIPYPHHNQSPRNTYQCAMGKQAMGTIGYNQRNRIDTLMYLLAYPQKP 718
            IEPFTLLGVCAGLIPYPHHNQSPRNTYQCAMGKQAMGTIGYNQRNRIDTLMYLLAYPQKP
Sbjct: 601  IEPFTLLGVCAGLIPYPHHNQSPRNTYQCAMGKQAMGTIGYNQRNRIDTLMYLLAYPQKP 660

Query: 719  MVKTKTIELIEFEKLPAGQNATVAVMSYSGYDIEDALVLNKASLDRGFGRCLVYKNAKCT 778
            MVKTKTIELIEFEKLPAGQNATVAVMSYSGYDIEDALVLNKASLDRGFGRCLVYKNAKCT
Sbjct: 661  MVKTKTIELIEFEKLPAGQNATVAVMSYSGYDIEDALVLNKASLDRGFGRCLVYKNAKCT 720

Query: 779  LKRYTNQTFDKVMGPMLDAATRKPIWRHEILDADGICSPGEKVENKQVLVNKSMPTVTQI 838
            LKRYTNQTFDKVMGPMLDAATRKPIWRHEILDADGICSPGEKVENKQVLVNKSMPTVTQI
Sbjct: 721  LKRYTNQTFDKVMGPMLDAATRKPIWRHEILDADGICSPGEKVENKQVLVNKSMPTVTQI 780

Query: 839  PLEGSNVPQQPQYKDVPITYKGATDSYIEKVMISSNAEDAFLIKMLLRQTRRPEIGDKFS 898
            PLEGSNVPQQPQYKDVPITYKGATDSYIEKVMISSNAEDAFLIKMLLRQTRRPEIGDKFS
Sbjct: 781  PLEGSNVPQQPQYKDVPITYKGATDSYIEKVMISSNAEDAFLIKMLLRQTRRPEIGDKFS 840

Query: 899  SRHGQKGVCGLIVPQEDMPFCDSGICPDIIMNPHGFPSRMTVGKLIELLAGKAGVLDGRF 958
            SRHGQKGVCGLIVPQEDMPFCDSGICPDIIMNPHGFPSRMTVGKLIELLAGKAGVLDGRF
Sbjct: 841  SRHGQKGVCGLIVPQEDMPFCDSGICPDIIMNPHGFPSRMTVGKLIELLAGKAGVLDGRF 900

Query: 959  HYGTAFGGSKVKDVCEDLVRHGYNYLGKDYVTSGITGEPLEAYIYFGPVYYQKLKHMVLD 1018
            HYGTAFGGSKVKDVCEDLVRHGYNYLGKDYVTSGITGEPLEAYIYFGPVYYQKLKHMVLD
Sbjct: 901  HYGTAFGGSKVKDVCEDLVRHGYNYLGKDYVTSGITGEPLEAYIYFGPVYYQKLKHMVLD 960

Query: 1019 KMHARARGPRAVLTRQPTEGRSRDGGLRLGEMERDCLIGYGASMLLLERLMISSDAFEVD 1078
            KMHARARGPRAVLTRQPTEGRSRDGGLRLGEMERDCLIGYGASMLLLERLMISSDAFEVD
Sbjct: 961  KMHARARGPRAVLTRQPTEGRSRDGGLRLGEMERDCLIGYGASMLLLERLMISSDAFEVD 1020

Query: 1079 VCGQCGLLGYSGWCHYCKSSCHVSSLRIPYACKLLFQELQSMNIIPRLKLSKYNE 1133
            VCGQCGLLGYSGWCHYCKSSCHVSSLRIPYACKLLFQELQSMNIIPRLKLSKYNE
Sbjct: 1021 VCGQCGLLGYSGWCHYCKSSCHVSSLRIPYACKLLFQELQSMNIIPRLKLSKYNE 1075


>gi|4505941 DNA directed RNA polymerase II polypeptide B [Homo
            sapiens]
          Length = 1174

 Score =  767 bits (1981), Expect = 0.0
 Identities = 447/1164 (38%), Positives = 688/1164 (59%), Gaps = 77/1164 (6%)

Query: 24   EEKWRLLPAFLKVKGLVKQHIDSFNYFINVEIKKIMKANEKVTSDAD-----------PM 72
            E  W ++ ++   KGLV+Q +DSF+ FI + +++I++    +   A+           P 
Sbjct: 24   EACWIVISSYFDEKGLVRQQLDSFDEFIQMSVQRIVEDAPPIDLQAEAQHASGEVEEPPR 83

Query: 73   WYLKYLNIYVGLPDVEESFNVTRPVSPHECRLRDMTYSAPITVDIEYT---RGSQRIIRN 129
            + LK+  IY+  P   E      P+ P+E RLR++TYSAP+ VDI  T    G +++   
Sbjct: 84   YLLKFEQIYLSKPTHWERDGAPSPMMPNEARLRNLTYSAPLYVDITKTVIKEGEEQLQTQ 143

Query: 130  ALP--IGRMPIMLRSSNCVLTGKTPAEFAKLNECPLDPGGYFIVKGVEKVILIQEQLSKN 187
                 IG++PIMLRS+ C+L G T  +  +LNECPLDPGGYFI+ G EKV++ QE+++ N
Sbjct: 144  HQKTFIGKIPIMLRSTYCLLNGLTDRDLCELNECPLDPGGYFIINGSEKVLIAQEKMATN 203

Query: 188  RIIVEA--DRKGAVGASVTSSTHEKKSRTN-----MAVKQG----------RFYLRHNTL 230
             + V A  D K A      S        T+     M  + G          R       +
Sbjct: 204  TVYVFAKKDSKYAYTGECRSCLENSSRPTSTIWVSMLARGGQGAKKSAIGQRIVATLPYI 263

Query: 231  SEDIPIVIIFKAMGVESDQEIVQMI---GTEEHVMAAFGPSLEECQKAQIFTQMQALKYI 287
             +++PI+I+F+A+G  SD++I++ I     +  +M    PSL+E    Q   Q  AL +I
Sbjct: 264  KQEVPIIIVFRALGFVSDRDILEHIIYDFEDPEMMEMVKPSLDEAFVIQ--EQNVALNFI 321

Query: 288  GNKVRRQRMWGGGPKKTKIEEARELLASTILTHVPVKEFNFRAKCIYTAVMVRRVILAQ- 346
            G++  +     G  K+ +I+ A+E+L   +L HV V +F    K  +   MV R++LA  
Sbjct: 322  GSRGAKP----GVTKEKRIKYAKEVLQKEMLPHVGVSDFCETKKAYFLGYMVHRLLLAAL 377

Query: 347  GDNKVDDRDYYGNKRLELAGQLLSLLFEDLFKKFNSEMKKIADQVIPKQRAAQFDVVKHM 406
            G  ++DDRD+YGNKRL+LAG LL+ LF  +FK    E++  A + I   R   F++   +
Sbjct: 378  GRRELDDRDHYGNKRLDLAGPLLAFLFRGMFKNLLKEVRIYAQKFI--DRGKDFNLELAI 435

Query: 407  RQDQITNGMVNAISTGNWS-LKRFKMDRQGVTQVLSRLSYISALGMMTRISSQFEKTRKV 465
            +   I++G+  +++TGNW   K+    R GV+QVL+RL++ S L  + R++S   +  K+
Sbjct: 436  KTRIISDGLKYSLATGNWGDQKKAHQARAGVSQVLNRLTFASTLSHLRRLNSPIGRDGKL 495

Query: 466  SGPRSLQPSQWGMLCPSDTPEGEACGLVKNLALMTHITTDMEDGPIVKLASNLGVEDVNL 525
            + PR L  + WGM+CP++TPEG A GLVKNLALM +I+   +  PI++      +E++  
Sbjct: 496  AKPRQLHNTLWGMVCPAETPEGHAVGLVKNLALMAYISVGSQPSPILEFLEEWSMENLEE 555

Query: 526  LCGEELSYPNVFLVFLNGNILGVIRDHKKLVNTFRLMRRA-GYINEFVSISTNLTDRCVY 584
            +    ++  +   +F+NG  +G+ +D ++L+NT R +RR    I   VS+  ++ +R + 
Sbjct: 556  ISPAAIA--DATKIFVNGCWVGIHKDPEQLMNTLRKLRRQMDIIVSEVSMIRDIREREIR 613

Query: 585  ISSDGGRLCRPYIIVKKQKPAVTNKHMEELAQG-YRNF--EDFLHESLVEYLDVNEENDC 641
            I +D GR+CRP +IV+KQK  +  +H+++L +  Y N+  +D +   +VEY+D  EE   
Sbjct: 614  IYTDAGRICRPLLIVEKQKLLLKKRHIDQLKEREYNNYSWQDLVASGVVEYIDTLEEETV 673

Query: 642  NIALYEHTINKDT-------THLEIEPFTLLGVCAGLIPYPHHNQSPRNTYQCAMGKQAM 694
             +A+    + +         TH EI P  +LGVCA +IP+P HNQSPRNTYQ AMGKQAM
Sbjct: 674  MLAMTPDDLQEKEVAYCSTYTHCEIHPSMILGVCASIIPFPDHNQSPRNTYQSAMGKQAM 733

Query: 695  GTIGYNQRNRIDTLMYLLAYPQKPMVKTKTIELIEFEKLPAGQNATVAVMSYSGYDIEDA 754
            G    N   R+DTL ++L YPQKP+V T+++E + F +LPAG N+ VA+ SY+GY+ ED+
Sbjct: 734  GVYITNFHVRMDTLAHVLYYPQKPLVTTRSMEYLRFRELPAGINSIVAIASYTGYNQEDS 793

Query: 755  LVLNKASLDRGFGRCLVYKNAKCTLKRYTNQTFDKVMGPMLDAATRKPI--WRHEI---L 809
            +++N++++DRGF R + Y++ K   ++ + + FD+    + +  TR+     RH I   L
Sbjct: 794  VIMNRSAVDRGFFRSVFYRSYK---EQESKKGFDQ--EEVFEKPTRETCQGMRHAIYDKL 848

Query: 810  DADGICSPGEKVENKQVLVNKSMPTVTQIPLEGSNVPQQPQYKDVPITYKGATDSYIEKV 869
            D DG+ +PG +V    V++ K++ T+ +   E  +  ++   +D     + +    +++V
Sbjct: 849  DDDGLIAPGVRVSGDDVIIGKTV-TLPENEDELESTNRRYTKRDCSTFLRTSETGIVDQV 907

Query: 870  MISSNAEDAFLIKMLLRQTRRPEIGDKFSSRHGQKGVCGLIVPQEDMPFCDSGICPDIIM 929
            M++ N E     K+ +R  R P+IGDKF+SRHGQKG CG+   QEDMPF   GI PDII+
Sbjct: 908  MVTLNQEGYKFCKIRVRSVRIPQIGDKFASRHGQKGTCGIQYRQEDMPFTCEGITPDIII 967

Query: 930  NPHGFPSRMTVGKLIELLAGKAGVLDGRFHYGTAFGGS-KVKDVCEDLVRHGYNYLGKDY 988
            NPH  PSRMT+G LIE L GK     G     T F  +  V+ +   L  +GY+  G + 
Sbjct: 968  NPHAIPSRMTIGHLIECLQGKVSANKGEIGDATPFNDAVNVQKISNLLSDYGYHLRGNEV 1027

Query: 989  VTSGITGEPLEAYIYFGPVYYQKLKHMVLDKMHARARGPRAVLTRQPTEGRSRDGGLRLG 1048
            + +G TG  + + I+ GP YYQ+LKHMV DK+H+RARGP  +L RQP EGRSRDGGLR G
Sbjct: 1028 LYNGFTGRKITSQIFIGPTYYQRLKHMVDDKIHSRARGPIQILNRQPMEGRSRDGGLRFG 1087

Query: 1049 EMERDCLIGYGASMLLLERLMISSDAFEVDVCGQCGLLGYSGW------CHYCKSSCHVS 1102
            EMERDC I +GA+  L ERL  +SD ++V VC  CG++  +        C  C++   +S
Sbjct: 1088 EMERDCQIAHGAAQFLRERLFEASDPYQVHVCNLCGIMAIANTRTHTYECRGCRNKTQIS 1147

Query: 1103 SLRIPYACKLLFQELQSMNIIPRL 1126
             +R+PYACKLLFQEL SM+I PR+
Sbjct: 1148 LVRMPYACKLLFQELMSMSIAPRM 1171


>gi|33469941 RNA polymerase I polypeptide B isoform 1 [Homo sapiens]
          Length = 1135

 Score =  406 bits (1044), Expect = e-113
 Identities = 348/1153 (30%), Positives = 521/1153 (45%), Gaps = 123/1153 (10%)

Query: 39   LVKQHIDSFNYFINVEIKKIMKANEKVT-SDADPMWYLKYLNIYVGLPDVEESFNVTRP- 96
            L + H++SFNY ++  +   ++A      +  D       L+  +  P V +        
Sbjct: 38   LTRAHVESFNYAVHEGLGLAVQAIPPFEFAFKDERISFTILDAVISPPTVPKGTICKEAN 97

Query: 97   VSPHECRLRDMTYSAPITVDIEYTRG--SQRIIRNALPIGRMPIMLRSSNCVLTGKTPAE 154
            V P ECR R  TY   +T DI +     S+ II+  L  G +PIM++S  C L    P  
Sbjct: 98   VYPAECRGRRSTYRGKLTADINWAVNGISKGIIKQFL--GYVPIMVKSKLCNLRNLPPQA 155

Query: 155  FAKLNECPLDPGGYFIVKGVEKVILIQEQLSKNRIIVEADRKGAV-GASVTS---STHEK 210
              + +E   + GGYFI+ G+EKVI +     +N  I     K    G   T    S H  
Sbjct: 156  LIEHHEEAEEMGGYFIINGIEKVIRMLIMPRRNFPIAMIRPKWKTRGPGYTQYGVSMHCV 215

Query: 211  KSRTNMAVKQGRFYLRHNTLSED---------IPIVIIFKAMGVESDQEIVQMI--GTEE 259
            +   + AV     YL + T+  +         +P+    KA+   SD +I Q +  G E+
Sbjct: 216  REE-HSAVNMNLHYLENGTVMLNFIYRKELFFLPLGFALKALVSFSDYQIFQELIKGKED 274

Query: 260  H--VMAAFGPSLEECQKAQIFTQMQALKYIGNKVRRQRMWGGGPKKTKIEEARELLAST- 316
               +  +    L    +    TQ Q L Y+G   R +      P     E+A E L +  
Sbjct: 275  DSFLRNSVSQMLRIVMEEGCSTQKQVLNYLGECFRVKL---NVPDWYPNEQAAEFLFNQC 331

Query: 317  ILTHVPVKEFNFRAKCIYTAVMVRRVILAQGDNKVDDRDYYGNKRLELAGQLLSLLFEDL 376
            I  H+      F   C+ T  +     LA+G+   D+ D   N+ +   GQL  +  ++ 
Sbjct: 332  ICIHLKSNTEKFYMLCLMTRKLFA---LAKGECMEDNPDSLVNQEVLTPGQLFLMFLKEK 388

Query: 377  FKKFNSEMKKIADQVIPKQRAAQFDVVKHMR----QDQITNGMVNAISTGNWSLKRFK-- 430
             + +   +K   D+   K  +   +    MR       +T       +TGN   K     
Sbjct: 389  LEGWLVSIKIAFDKKAQKT-SVSMNTDNLMRIFTMGIDLTKPFEYLFATGNLRSKTGLGL 447

Query: 431  MDRQGVTQVLSRLSYISALGMMTRI--SSQFEKTRKVSGPRSLQPSQWGMLCPSDTPEGE 488
            +   G+  V  +L++I  L     +   + F K R  +  R L P  WG LCP  TP+GE
Sbjct: 448  LQDSGLCVVADKLNFIRYLSHFRCVHRGADFAKMRTTT-VRRLLPESWGFLCPVHTPDGE 506

Query: 489  ACGLVKNLALMTHITTD-MEDGPIVKLASNLGVEDVNLLCGEELSYPNVFLVFLNGNILG 547
             CGL+ +L  +  + T  +    I  L  NLGV  ++       SY   + V L+G ++G
Sbjct: 507  PCGLMNHLTAVCEVVTQFVYTASIPALLCNLGVTPID--GAPHRSYSECYPVLLDGVMVG 564

Query: 548  VIRDH-----KKLVNTFRLMRRAGYINEFVSISTNLTDRC-----VYISSDGGRLCRPYI 597
             +           +  F+++R          +   +T +      +++ +   RL RP  
Sbjct: 565  WVDKDLAPGIADSLRHFKVLREKRIPPWMEVVLIPMTGKPSLYPGLFLFTTPCRLVRP-- 622

Query: 598  IVKKQKPAVTNKHMEELAQGYRNFEDFLHESLVEYLDVNEENDCNIALYEHTINKD-TTH 656
                         ++ LA G             E +   E+   N+A++E  +    TTH
Sbjct: 623  -------------VQNLALGKE-----------ELIGTMEQIFMNVAIFEDEVFAGVTTH 658

Query: 657  LEIEPFTLLGVCAGLIPYPHHNQSPRNTYQCAMGKQAMGTIGYNQRNRIDTLMYLLAYPQ 716
             E+ P +LL V A  IP+  HNQSPRN YQC MGKQ MG      ++R D  +Y L  PQ
Sbjct: 659  QELFPHSLLSVIANFIPFSDHNQSPRNMYQCQMGKQTMGFPLLTYQDRSDNKLYRLQTPQ 718

Query: 717  KPMVKTKTIELIEFEKLPAGQNATVAVMSYSGYDIEDALVLNKASLDRGFGRCLVYKNAK 776
             P+V+    +  + +  P G NA VAV+SY+GYD+EDA+++NKAS +RGF    VYK+  
Sbjct: 719  SPLVRPSMYDYYDMDNYPIGTNAIVAVISYTGYDMEDAMIVNKASWERGFAHGSVYKSEF 778

Query: 777  CTLKRYTNQTFDKVMGPMLDAATRKPIWRHEILDADGICSPGEKVENKQVLVNKSMPTVT 836
              L     Q    ++  +     R      + LD DG+   G K++          P  +
Sbjct: 779  IDLSEKIKQGDSSLVFGIKPGDPRVL----QKLDDDGLPFIGAKLQYGD-------PYYS 827

Query: 837  QIPLEGSNVPQQPQYKDVPITYKGATDSYIEKVMISSNAEDAFLIKML---LRQTRRPEI 893
             + L           +   + YK   +  ++ + + SN   +   K +   +R  R P I
Sbjct: 828  YLNLNTG--------ESFVMYYKSKENCVVDNIKVCSNDTGSGKFKCVCITMRVPRNPTI 879

Query: 894  GDKFSSRHGQKGVCGLIVPQEDMPFCDSGICPDIIMNPHGFPSRMTVGKLIELLAGKAGV 953
            GDKF+SRHGQKG+   + P EDMPF +SG+ PDI+ NPHGFPSRMT+G LIE +AGK+  
Sbjct: 880  GDKFASRHGQKGILSRLWPAEDMPFTESGMVPDILFNPHGFPSRMTIGMLIESMAGKSAA 939

Query: 954  LDGRFHYGTAF----GGSKVKDVCEDLVRHGYNYLGKDYVTSGITGEPLEAYIYFGPVYY 1009
            L G  H  T F      S ++   E L   GYN+ G + + SGI+G  LEA I+ G VYY
Sbjct: 940  LHGLCHDATPFIFSEENSALEYFGEMLKAAGYNFYGTERLYSGISGLELEADIFIGVVYY 999

Query: 1010 QKLKHMVLDKMHARARGPRAVLTRQPTEGRSRDGGLRLGEMERDCLIGYGASMLLLERLM 1069
            Q+L+HMV DK   R  G R  +T QP  GR+  GG+R GEMERD L+ +G S LL +RL 
Sbjct: 1000 QRLRHMVSDKFQVRTTGARDRVTNQPIGGRNVQGGIRFGEMERDALLAHGTSFLLHDRLF 1059

Query: 1070 ISSDAFEVDVCGQCGLL-------GYSGW---------CHYCKSSCHVSSLRIPYACKLL 1113
              SD     VC +CG L           W         C  C  S  + ++ +PY  +  
Sbjct: 1060 NCSDRSVAHVCVKCGSLLSPLLEKPPPSWSAMRNRKYNCTLCSRSDTIDTVSVPYVFRYF 1119

Query: 1114 FQELQSMNIIPRL 1126
              EL +MNI  +L
Sbjct: 1120 VAELAAMNIKVKL 1132


>gi|212286172 RNA polymerase I polypeptide B isoform 2 [Homo sapiens]
          Length = 1079

 Score =  388 bits (997), Expect = e-107
 Identities = 322/1055 (30%), Positives = 480/1055 (45%), Gaps = 117/1055 (11%)

Query: 133  IGRMPIMLRSSNCVLTGKTPAEFAKLNECPLDPGGYFIVKGVEKVILIQEQLSKNRIIVE 192
            +G +PIM++S  C L    P    + +E   + GGYFI+ G+EKVI +     +N  I  
Sbjct: 78   LGYVPIMVKSKLCNLRNLPPQALIEHHEEAEEMGGYFIINGIEKVIRMLIMPRRNFPIAM 137

Query: 193  ADRKGAV-GASVTS---STHEKKSRTNMAVKQGRFYLRHNTLSED---------IPIVII 239
               K    G   T    S H  +   + AV     YL + T+  +         +P+   
Sbjct: 138  IRPKWKTRGPGYTQYGVSMHCVREE-HSAVNMNLHYLENGTVMLNFIYRKELFFLPLGFA 196

Query: 240  FKAMGVESDQEIVQMI--GTEEH--VMAAFGPSLEECQKAQIFTQMQALKYIGNKVRRQR 295
             KA+   SD +I Q +  G E+   +  +    L    +    TQ Q L Y+G   R + 
Sbjct: 197  LKALVSFSDYQIFQELIKGKEDDSFLRNSVSQMLRIVMEEGCSTQKQVLNYLGECFRVKL 256

Query: 296  MWGGGPKKTKIEEARELLAST-ILTHVPVKEFNFRAKCIYTAVMVRRVILAQGDNKVDDR 354
                 P     E+A E L +  I  H+      F   C+ T  +     LA+G+   D+ 
Sbjct: 257  ---NVPDWYPNEQAAEFLFNQCICIHLKSNTEKFYMLCLMTRKLFA---LAKGECMEDNP 310

Query: 355  DYYGNKRLELAGQLLSLLFEDLFKKFNSEMKKIADQVIPKQRAAQFDVVKHMR----QDQ 410
            D   N+ +   GQL  +  ++  + +   +K   D+   K  +   +    MR       
Sbjct: 311  DSLVNQEVLTPGQLFLMFLKEKLEGWLVSIKIAFDKKAQKT-SVSMNTDNLMRIFTMGID 369

Query: 411  ITNGMVNAISTGNWSLKRFK--MDRQGVTQVLSRLSYISALGMMTRI--SSQFEKTRKVS 466
            +T       +TGN   K     +   G+  V  +L++I  L     +   + F K R  +
Sbjct: 370  LTKPFEYLFATGNLRSKTGLGLLQDSGLCVVADKLNFIRYLSHFRCVHRGADFAKMRTTT 429

Query: 467  GPRSLQPSQWGMLCPSDTPEGEACGLVKNLALMTHITTD-MEDGPIVKLASNLGVEDVNL 525
              R L P  WG LCP  TP+GE CGL+ +L  +  + T  +    I  L  NLGV  ++ 
Sbjct: 430  -VRRLLPESWGFLCPVHTPDGEPCGLMNHLTAVCEVVTQFVYTASIPALLCNLGVTPID- 487

Query: 526  LCGEELSYPNVFLVFLNGNILGVIRDH-----KKLVNTFRLMRRAGYINEFVSISTNLTD 580
                  SY   + V L+G ++G +           +  F+++R          +   +T 
Sbjct: 488  -GAPHRSYSECYPVLLDGVMVGWVDKDLAPGIADSLRHFKVLREKRIPPWMEVVLIPMTG 546

Query: 581  RC-----VYISSDGGRLCRPYIIVKKQKPAVTNKHMEELAQGYRNFEDFLHESLVEYLDV 635
            +      +++ +   RL RP               ++ LA G             E +  
Sbjct: 547  KPSLYPGLFLFTTPCRLVRP---------------VQNLALGKE-----------ELIGT 580

Query: 636  NEENDCNIALYEHTINKD-TTHLEIEPFTLLGVCAGLIPYPHHNQSPRNTYQCAMGKQAM 694
             E+   N+A++E  +    TTH E+ P +LL V A  IP+  HNQSPRN YQC MGKQ M
Sbjct: 581  MEQIFMNVAIFEDEVFAGVTTHQELFPHSLLSVIANFIPFSDHNQSPRNMYQCQMGKQTM 640

Query: 695  GTIGYNQRNRIDTLMYLLAYPQKPMVKTKTIELIEFEKLPAGQNATVAVMSYSGYDIEDA 754
            G      ++R D  +Y L  PQ P+V+    +  + +  P G NA VAV+SY+GYD+EDA
Sbjct: 641  GFPLLTYQDRSDNKLYRLQTPQSPLVRPSMYDYYDMDNYPIGTNAIVAVISYTGYDMEDA 700

Query: 755  LVLNKASLDRGFGRCLVYKNAKCTLKRYTNQTFDKVMGPMLDAATRKPIWRHEILDADGI 814
            +++NKAS +RGF    VYK+    L     Q    ++  +     R      + LD DG+
Sbjct: 701  MIVNKASWERGFAHGSVYKSEFIDLSEKIKQGDSSLVFGIKPGDPRVL----QKLDDDGL 756

Query: 815  CSPGEKVENKQVLVNKSMPTVTQIPLEGSNVPQQPQYKDVPITYKGATDSYIEKVMISSN 874
               G K++          P  + + L           +   + YK   +  ++ + + SN
Sbjct: 757  PFIGAKLQYGD-------PYYSYLNLNTG--------ESFVMYYKSKENCVVDNIKVCSN 801

Query: 875  AEDAFLIKML---LRQTRRPEIGDKFSSRHGQKGVCGLIVPQEDMPFCDSGICPDIIMNP 931
               +   K +   +R  R P IGDKF+SRHGQKG+   + P EDMPF +SG+ PDI+ NP
Sbjct: 802  DTGSGKFKCVCITMRVPRNPTIGDKFASRHGQKGILSRLWPAEDMPFTESGMVPDILFNP 861

Query: 932  HGFPSRMTVGKLIELLAGKAGVLDGRFHYGTAF----GGSKVKDVCEDLVRHGYNYLGKD 987
            HGFPSRMT+G LIE +AGK+  L G  H  T F      S ++   E L   GYN+ G +
Sbjct: 862  HGFPSRMTIGMLIESMAGKSAALHGLCHDATPFIFSEENSALEYFGEMLKAAGYNFYGTE 921

Query: 988  YVTSGITGEPLEAYIYFGPVYYQKLKHMVLDKMHARARGPRAVLTRQPTEGRSRDGGLRL 1047
             + SGI+G  LEA I+ G VYYQ+L+HMV DK   R  G R  +T QP  GR+  GG+R 
Sbjct: 922  RLYSGISGLELEADIFIGVVYYQRLRHMVSDKFQVRTTGARDRVTNQPIGGRNVQGGIRF 981

Query: 1048 GEMERDCLIGYGASMLLLERLMISSDAFEVDVCGQCGLL-------GYSGW--------- 1091
            GEMERD L+ +G S LL +RL   SD     VC +CG L           W         
Sbjct: 982  GEMERDALLAHGTSFLLHDRLFNCSDRSVAHVCVKCGSLLSPLLEKPPPSWSAMRNRKYN 1041

Query: 1092 CHYCKSSCHVSSLRIPYACKLLFQELQSMNIIPRL 1126
            C  C  S  + ++ +PY  +    EL +MNI  +L
Sbjct: 1042 CTLCSRSDTIDTVSVPYVFRYFVAELAAMNIKVKL 1076


>gi|20128768 serine/threonine kinase 35 [Homo sapiens]
          Length = 401

 Score = 32.3 bits (72), Expect = 2.6
 Identities = 25/86 (29%), Positives = 41/86 (47%), Gaps = 11/86 (12%)

Query: 588 DGGRLCRPYIIVKKQKPAVTNKHMEELAQGYRNFEDFLHESLVEYLDVNEENDCNIALYE 647
           +GG L   Y++ ++  PA     M +L         FLH++ + + D+  +N   I + E
Sbjct: 186 EGGDL-NQYVLSRRPDPATNKSFMLQLTSAIA----FLHKNHIVHRDLKPDN---ILITE 237

Query: 648 HTINKDTTHLEIEPFTLLGVCAGLIP 673
            +    T  L++  F L  VCAGL P
Sbjct: 238 RS---GTPILKVADFGLSKVCAGLAP 260


>gi|116063536 coenzyme Q5 homolog, methyltransferase [Homo sapiens]
          Length = 327

 Score = 31.2 bits (69), Expect = 5.8
 Identities = 17/39 (43%), Positives = 23/39 (58%)

Query: 600 KKQKPAVTNKHMEELAQGYRNFEDFLHESLVEYLDVNEE 638
           K+Q  A  N   EE+A+ Y+N ED L  S V   D+N+E
Sbjct: 137 KRQLRAQQNLSWEEIAKEYQNEEDSLGGSRVVVCDINKE 175


>gi|123701326 zinc finger protein 831 [Homo sapiens]
          Length = 1677

 Score = 30.8 bits (68), Expect = 7.6
 Identities = 23/79 (29%), Positives = 37/79 (46%), Gaps = 3/79 (3%)

Query: 870  MISSNAEDAFLIKMLLR--QTRRP-EIGDKFSSRHGQKGVCGLIVPQEDMPFCDSGICPD 926
            ++S+ A++AF  K LLR  Q   P  +   +  RH Q  +C    P+E   F  SG+   
Sbjct: 928  VLSALADNAFSPKYLLRLPQAETPLPLPIPWGPRHSQDSLCSSGWPEERASFVGSGLGTP 987

Query: 927  IIMNPHGFPSRMTVGKLIE 945
            +  +P   PS      ++E
Sbjct: 988  LSPSPASGPSPGEADSILE 1006


>gi|20357504 dystonin isoform 1eB precursor [Homo sapiens]
          Length = 3062

 Score = 30.4 bits (67), Expect = 9.9
 Identities = 21/87 (24%), Positives = 35/87 (40%)

Query: 435  GVTQVLSRLSYISALGMMTRISSQFEKTRKVSGPRSLQPSQWGMLCPSDTPEGEACGLVK 494
            G T +   L  +S+ G+    +S  EK    + P S      G     +TPE   C + +
Sbjct: 1706 GNTAIKECLDVLSSSGVFLNNASGREKDECTATPSSFNKCHCGEPEHEETPENRKCAIDE 1765

Query: 495  NLALMTHITTDMEDGPIVKLASNLGVE 521
                M +   + E     KLAS + ++
Sbjct: 1766 EFNEMRNTVINSEFSQSGKLASTISID 1792


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.137    0.406 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 41,738,789
Number of Sequences: 37866
Number of extensions: 1880297
Number of successful extensions: 3780
Number of sequences better than 10.0: 9
Number of HSP's better than 10.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 3743
Number of HSP's gapped (non-prelim): 16
length of query: 1133
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1020
effective length of database: 13,968,660
effective search space: 14248033200
effective search space used: 14248033200
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.