Search of human proteins with 222537716

Search of human proteins with 222537716

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|222537716 sorting nexin 31 [Homo sapiens]
         (440 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|222537716 sorting nexin 31 [Homo sapiens]                          891   0.0  
gi|7661890 sorting nexin 17 [Homo sapiens]                            311   6e-85
gi|31742501 sorting nexin family member 27 [Homo sapiens]             119   7e-27
gi|71772838 sorting nexin 22 [Homo sapiens]                            40   0.004
gi|7662655 SBBI31 protein [Homo sapiens]                               37   0.036
gi|23111038 sorting nexin 2 [Homo sapiens]                             35   0.14 
gi|23111036 sorting nexin 1 isoform c [Homo sapiens]                   32   0.88 
gi|23111032 sorting nexin 1 isoform b [Homo sapiens]                   32   0.88 
gi|23111034 sorting nexin 1 isoform a [Homo sapiens]                   32   0.88 
gi|45439370 TAO kinase 1 [Homo sapiens]                                30   3.3  
gi|93141033 PAX interacting protein 1 [Homo sapiens]                   29   7.4  
gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo...    29   7.4  
gi|4507143 sorting nexin 3 isoform a [Homo sapiens]                    29   7.4  
gi|139948432 adlican [Homo sapiens]                                    29   7.4  
gi|221219020 NYD-SP11 protein [Homo sapiens]                           29   9.7  
gi|194239633 solute carrier family 44, member 5 isoform B [Homo ...    29   9.7  

>gi|222537716 sorting nexin 31 [Homo sapiens]
          Length = 440

 Score =  891 bits (2302), Expect = 0.0
 Identities = 440/440 (100%), Positives = 440/440 (100%)

Query: 1   MKMHFCIPVSQQRSDALGGRYVLYSVHLDGFLFCRVRYSQLHGWNEQLRRVFGNCLPPFP 60
           MKMHFCIPVSQQRSDALGGRYVLYSVHLDGFLFCRVRYSQLHGWNEQLRRVFGNCLPPFP
Sbjct: 1   MKMHFCIPVSQQRSDALGGRYVLYSVHLDGFLFCRVRYSQLHGWNEQLRRVFGNCLPPFP 60

Query: 61  PKYYLAMTTAMADERRDQLEQYLQNVTMDPNVLRSDVFVEFLKLAQLNTFDIATKKAYLD 120
           PKYYLAMTTAMADERRDQLEQYLQNVTMDPNVLRSDVFVEFLKLAQLNTFDIATKKAYLD
Sbjct: 61  PKYYLAMTTAMADERRDQLEQYLQNVTMDPNVLRSDVFVEFLKLAQLNTFDIATKKAYLD 120

Query: 121 IFLPNEQSIRIEIITSDTAERVLEVVSHKIGLCRELLGYFGLFLIRFGKEGKLSVVKKLA 180
           IFLPNEQSIRIEIITSDTAERVLEVVSHKIGLCRELLGYFGLFLIRFGKEGKLSVVKKLA
Sbjct: 121 IFLPNEQSIRIEIITSDTAERVLEVVSHKIGLCRELLGYFGLFLIRFGKEGKLSVVKKLA 180

Query: 181 DFELPYVSLGSSEVENCKVGLRKWYMAPSLDSVLMDCRVAVDLLYMQAIQDIEKGWAKPT 240
           DFELPYVSLGSSEVENCKVGLRKWYMAPSLDSVLMDCRVAVDLLYMQAIQDIEKGWAKPT
Sbjct: 181 DFELPYVSLGSSEVENCKVGLRKWYMAPSLDSVLMDCRVAVDLLYMQAIQDIEKGWAKPT 240

Query: 241 QAQRQKLEAFQKEDSQTKFLELAREVRHYGYLQLDPCTCDYPESGSGAVLSVGNNEISCC 300
           QAQRQKLEAFQKEDSQTKFLELAREVRHYGYLQLDPCTCDYPESGSGAVLSVGNNEISCC
Sbjct: 241 QAQRQKLEAFQKEDSQTKFLELAREVRHYGYLQLDPCTCDYPESGSGAVLSVGNNEISCC 300

Query: 301 ITLPDSQTQDIVFQMSRVKCWQVTFLGTLLDTDGPQRTLNQNLELRFQYSEDSCWQWFVI 360
           ITLPDSQTQDIVFQMSRVKCWQVTFLGTLLDTDGPQRTLNQNLELRFQYSEDSCWQWFVI
Sbjct: 301 ITLPDSQTQDIVFQMSRVKCWQVTFLGTLLDTDGPQRTLNQNLELRFQYSEDSCWQWFVI 360

Query: 361 YTKQAFLLSSCLKKMISEKMVKLAAENTEMQIEVPEQSKSKKYHIQQSQQKDYSSFLSRK 420
           YTKQAFLLSSCLKKMISEKMVKLAAENTEMQIEVPEQSKSKKYHIQQSQQKDYSSFLSRK
Sbjct: 361 YTKQAFLLSSCLKKMISEKMVKLAAENTEMQIEVPEQSKSKKYHIQQSQQKDYSSFLSRK 420

Query: 421 SKIKIAKDDCVFGNIKEEDL 440
           SKIKIAKDDCVFGNIKEEDL
Sbjct: 421 SKIKIAKDDCVFGNIKEEDL 440


>gi|7661890 sorting nexin 17 [Homo sapiens]
          Length = 470

 Score =  311 bits (798), Expect = 6e-85
 Identities = 168/387 (43%), Positives = 249/387 (64%), Gaps = 8/387 (2%)

Query: 3   MHFCIPVSQQRS-DALGGRYVLYSVHLDGFLFCRVRYSQLHGWNEQLRRVFG-NCLPPFP 60
           MHF IP ++ RS D+ G  YV Y++H++G L CRVRYSQL G +EQLR+ +G N LP FP
Sbjct: 1   MHFSIPETESRSGDSGGSAYVAYNIHVNGVLHCRVRYSQLLGLHEQLRKEYGANVLPAFP 60

Query: 61  PKYYLAMTTAMADERRDQLEQYLQNVTMDPNVLRSDVFVEFLKLAQLNTFDIATKKAYLD 120
           PK   ++T A  ++RR+QLE+Y+Q V  DP +  S+ F  FL+ AQ  T  + T++  L+
Sbjct: 61  PKKLFSLTPAEVEQRREQLEKYMQAVRQDPLLGSSETFNSFLRRAQQETQQVPTEEVSLE 120

Query: 121 IFLPNEQSIRIEIITSDTAERVLEVVSHKIGLCRELLGYFGLFLIRFGKEGKLSVVKKLA 180
           + L N Q + + ++TSD  E VLE V+ K+ L  +L+GYF LFL+R  ++G  S V+KL 
Sbjct: 121 VLLSNGQKVLVNVLTSDQTEDVLEAVAAKLDLPDDLIGYFSLFLVREKEDGAFSFVRKLQ 180

Query: 181 DFELPYVSLGSSEVENCKVGLRKWYMAPSLDSVLMDCRVAVDLLYMQAIQDIEKGWAKPT 240
           +FELPYVS+ S   +  K+ LRK Y   + D  +M+ RV ++LLY Q + DIE+GW   T
Sbjct: 181 EFELPYVSVTSLRSQEYKIVLRKSYWDSAYDDDVMENRVGLNLLYAQTVSDIERGWILVT 240

Query: 241 QAQRQKLEAFQKEDSQTKFLELAREVRHYGYLQLDPCTCDYPESGSGAVLSVGNNEISCC 300
           + Q ++L++ Q++ S+ +FL LA+ +RHYGYL+ D C  D+PE     V+S GN+E+S  
Sbjct: 241 KEQHRQLKSLQEKVSKKEFLRLAQTLRHYGYLRFDACVADFPEKDCPVVVSAGNSELSLQ 300

Query: 301 ITLPDSQTQDIVFQMSRVKCWQVTFLGTLL--DTDGPQRTLNQ-NLELRFQY--SEDSCW 355
           + LP  Q ++  F+++R++CW+VT    L    T  P R   +  LEL F+Y  S+D   
Sbjct: 301 LRLPGQQLREGSFRVTRMRCWRVTSSVPLPSGSTSSPGRGRGEVRLELAFEYLMSKDRL- 359

Query: 356 QWFVIYTKQAFLLSSCLKKMISEKMVK 382
           QW  I + QA ++S CL+ M+ E MVK
Sbjct: 360 QWVTITSPQAIMMSICLQSMVDELMVK 386


>gi|31742501 sorting nexin family member 27 [Homo sapiens]
          Length = 528

 Score =  119 bits (297), Expect = 7e-27
 Identities = 91/381 (23%), Positives = 172/381 (45%), Gaps = 32/381 (8%)

Query: 7   IPVSQQRSDAL---GGRYVLYSVHLDGFLFCRVRYSQLHGWNEQLRRVFGN-CLPPFPPK 62
           +P+S  R   +   G ++V+Y+V++ G   C  RY +    ++ L+R F N   P  P K
Sbjct: 163 VPISVPRYKHVEQNGEKFVVYNVYMAGRQLCSKRYREFAILHQNLKREFANFTFPRLPGK 222

Query: 63  YYLAMTTAMADERRDQLEQYLQNVTMDPNVLRSDVFVEFLKLAQLNTFDIATKKAYLDIF 122
           +  +++    D RR  LE+YL+ V     +  SD+  EFL  +  N   ++  +  L + 
Sbjct: 223 WPFSLSEQQLDARRRGLEEYLEKVCSIRVIGESDIMQEFLSESDENYNGVSDVE--LRVA 280

Query: 123 LPNEQSIRIEIITSDTAERVLEVVSHKIGLCRELLGYFGLFLIRFGKEGKLSVVKKLADF 182
           LP+  ++ + +  + T ++V + ++ K+G+    + YF LF +        S V+KLA  
Sbjct: 281 LPDGTTVTVRVKKNSTTDQVYQAIAAKVGMDSTTVNYFALFEVI-----SHSFVRKLAPN 335

Query: 183 ELP---YVSLGSSEVENCKVGLRKWYMAPSLDSVLMDCRVAVDLLYMQAIQDIEKGWAKP 239
           E P   Y+   +S V    + +RKW      + +L D  +AV   + QA+ D++KG+ K 
Sbjct: 336 EFPHKLYIQNYTSAVPGTCLTIRKWLFTTEEEILLNDNDLAVTYFFHQAVDDVKKGYIKA 395

Query: 240 TQAQRQKLEAFQKEDSQTKFLELAREVRHYGYLQLDPCTCDYPESGSG-AVLSVGNNEIS 298
            +   Q L+   ++     +L + R    Y  +    C CD    G     +S+ + ++ 
Sbjct: 396 EEKSYQ-LQKLYEQRKMVMYLNMLRTCEGYNEIIFPHCACDSRRKGHVITAISITHFKLH 454

Query: 299 CCITLPDSQTQDIVFQMSRVKCWQVTFLGTLLDTDGPQRTLNQNLELRFQYSE-DSCWQW 357
            C      + Q I F+   ++ W         DTD       + +   F+Y+  +   +W
Sbjct: 455 ACTEEGQLENQVIAFEWDEMQRW---------DTD------EEGMAFCFEYARGEKKPRW 499

Query: 358 FVIYTKQAFLLSSCLKKMISE 378
             I+T     +  C +++  E
Sbjct: 500 VKIFTPYFNYMHECFERVFCE 520


>gi|71772838 sorting nexin 22 [Homo sapiens]
          Length = 193

 Score = 40.0 bits (92), Expect = 0.004
 Identities = 26/92 (28%), Positives = 47/92 (51%), Gaps = 3/92 (3%)

Query: 37  RYSQLHGWNEQLRRVFGNCLPPFPPKYYLAMTTAMADERRDQLEQYLQNVTMDPNVLRSD 96
           RYS+ H  ++++++++   +P FP K      T   ++RR  LE Y+Q +      +  +
Sbjct: 43  RYSEFHALHKRIKKLYK--VPDFPSKRLPNWRTRGLEQRRQGLEAYIQGILYLNQEVPKE 100

Query: 97  VFVEFLKLAQLNTFDIATKKAYLDIFLPNEQS 128
           + +EFL+L    T   A+    L  FLP + S
Sbjct: 101 L-LEFLRLRHFPTDPKASNWGTLREFLPGDSS 131


>gi|7662655 SBBI31 protein [Homo sapiens]
          Length = 169

 Score = 37.0 bits (84), Expect = 0.036
 Identities = 22/75 (29%), Positives = 38/75 (50%), Gaps = 3/75 (4%)

Query: 33  FCRVRYSQLHGWNEQLRRVFGNCLPPFPPKYYLAMTTAMADERRDQLEQYLQNVTMDPNV 92
           F   RYS+ H  +++L++      P  P K+       + ++RR  LE YLQ V ++   
Sbjct: 34  FVEKRYSEFHALHKKLKKCIKT--PEIPSKHVRNWVPKVLEQRRQGLETYLQAVILENEE 91

Query: 93  LRSDVFVEFLKLAQL 107
           L   +F++FL +  L
Sbjct: 92  L-PKLFLDFLNVRHL 105


>gi|23111038 sorting nexin 2 [Homo sapiens]
          Length = 519

 Score = 35.0 bits (79), Expect = 0.14
 Identities = 24/85 (28%), Positives = 39/85 (45%), Gaps = 14/85 (16%)

Query: 37  RYSQLHGWNEQLRRVF---GNCLPPFPPKYYLAMT-----------TAMADERRDQLEQY 82
           R+S   G + +L   +   G  +PP P K  + MT           T   ++RR  LE+Y
Sbjct: 183 RFSDFLGLHSKLASKYLHVGYIVPPAPEKSIVGMTKVKVGKEDSSSTEFVEKRRAALERY 242

Query: 83  LQNVTMDPNVLRSDVFVEFLKLAQL 107
           LQ     P +L+     +FL+ ++L
Sbjct: 243 LQRTVKHPTLLQDPDLRQFLESSEL 267


>gi|23111036 sorting nexin 1 isoform c [Homo sapiens]
          Length = 474

 Score = 32.3 bits (72), Expect = 0.88
 Identities = 25/85 (29%), Positives = 37/85 (43%), Gaps = 14/85 (16%)

Query: 37  RYSQLHGWNEQLRRVF---GNCLPPFPPKYYLAMTTAMA-----------DERRDQLEQY 82
           R+S   G  E+L       G  +PP P K  + MT               ++RR  LE+Y
Sbjct: 186 RFSDFLGLYEKLSEKHSQNGFIVPPPPEKSLIGMTKVKVGKEDSSSAEFLEKRRAALERY 245

Query: 83  LQNVTMDPNVLRSDVFVEFLKLAQL 107
           LQ +   P +L+     EFL+  +L
Sbjct: 246 LQRIVNHPTMLQDPDVREFLEKEEL 270


>gi|23111032 sorting nexin 1 isoform b [Homo sapiens]
          Length = 457

 Score = 32.3 bits (72), Expect = 0.88
 Identities = 25/85 (29%), Positives = 37/85 (43%), Gaps = 14/85 (16%)

Query: 37  RYSQLHGWNEQLRRVF---GNCLPPFPPKYYLAMTTAMA-----------DERRDQLEQY 82
           R+S   G  E+L       G  +PP P K  + MT               ++RR  LE+Y
Sbjct: 121 RFSDFLGLYEKLSEKHSQNGFIVPPPPEKSLIGMTKVKVGKEDSSSAEFLEKRRAALERY 180

Query: 83  LQNVTMDPNVLRSDVFVEFLKLAQL 107
           LQ +   P +L+     EFL+  +L
Sbjct: 181 LQRIVNHPTMLQDPDVREFLEKEEL 205


>gi|23111034 sorting nexin 1 isoform a [Homo sapiens]
          Length = 522

 Score = 32.3 bits (72), Expect = 0.88
 Identities = 25/85 (29%), Positives = 37/85 (43%), Gaps = 14/85 (16%)

Query: 37  RYSQLHGWNEQLRRVF---GNCLPPFPPKYYLAMTTAMA-----------DERRDQLEQY 82
           R+S   G  E+L       G  +PP P K  + MT               ++RR  LE+Y
Sbjct: 186 RFSDFLGLYEKLSEKHSQNGFIVPPPPEKSLIGMTKVKVGKEDSSSAEFLEKRRAALERY 245

Query: 83  LQNVTMDPNVLRSDVFVEFLKLAQL 107
           LQ +   P +L+     EFL+  +L
Sbjct: 246 LQRIVNHPTMLQDPDVREFLEKEEL 270


>gi|45439370 TAO kinase 1 [Homo sapiens]
          Length = 1001

 Score = 30.4 bits (67), Expect = 3.3
 Identities = 21/63 (33%), Positives = 35/63 (55%), Gaps = 7/63 (11%)

Query: 378 EKMVKLAAENTEMQIEVPEQSKSK-KYHIQQSQQKDYSSFL-SRKSKIKIAKDDCVFGNI 435
           EK++K      E + +V    + K + HIQ  Q+K+ +SFL S+K + K+ K+      +
Sbjct: 512 EKLIKKHQAAMEKEAKVMSNEEKKFQQHIQAQQKKELNSFLESQKREYKLRKE-----QL 566

Query: 436 KEE 438
           KEE
Sbjct: 567 KEE 569


>gi|93141033 PAX interacting protein 1 [Homo sapiens]
          Length = 1069

 Score = 29.3 bits (64), Expect = 7.4
 Identities = 45/188 (23%), Positives = 74/188 (39%), Gaps = 35/188 (18%)

Query: 261 ELAREVRHYGYLQLDPCTCDYPESGSGAVLSVGNNEISCCITLPDSQTQDI-----VFQM 315
           E+ REV++Y    +DP      ++G      V  N ++  I   D    ++     VF +
Sbjct: 11  EMFREVKYYAVGDIDPQVIQLLKAGKAK--EVSYNALASHIISEDGDNPEVGEAREVFDL 68

Query: 316 SRVK-CWQVTFL--GTLLDTDGPQRTLNQNLELRFQYSEDSCWQWFVIYTKQAFLLSSCL 372
             VK  W +  +  GTLL  +G              +S +SC  +F I        ++CL
Sbjct: 69  PVVKPSWVILSVQCGTLLPVNG--------------FSPESCQIFFGI--------TACL 106

Query: 373 KKMISEKMVKLAAENTEM--QIEVPEQSKSKKYHIQQSQQKDYSSFLSRKSKIKIAKDDC 430
            ++ SE    L A  T      ++    K     + + + + Y   L R S IKI   D 
Sbjct: 107 SQVSSEDRSALWALVTFYGGDCQLTLNKKCTHLIVPEPKGEKYECALKRAS-IKIVTPDW 165

Query: 431 VFGNIKEE 438
           V   + E+
Sbjct: 166 VLDCVSEK 173


>gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo
           sapiens]
          Length = 1938

 Score = 29.3 bits (64), Expect = 7.4
 Identities = 12/39 (30%), Positives = 23/39 (58%)

Query: 362 TKQAFLLSSCLKKMISEKMVKLAAENTEMQIEVPEQSKS 400
           TK+    S   +K + EKMV L  E  ++Q++V  ++++
Sbjct: 863 TKEELARSEARRKELEEKMVSLLQEKNDLQLQVQSETEN 901


>gi|4507143 sorting nexin 3 isoform a [Homo sapiens]
          Length = 162

 Score = 29.3 bits (64), Expect = 7.4
 Identities = 27/103 (26%), Positives = 39/103 (37%), Gaps = 19/103 (18%)

Query: 7   IPVSQQRSDALG-GRYVLYSVHLDGFL--------FCRVRYSQLHGWNEQLRRVFGNCLP 57
           I VS  ++  +G GR+  Y + +   L          R RYS       +L R     +P
Sbjct: 31  IDVSNPQTVGVGRGRFTTYEIRVKTNLPIFKLKESTVRRRYSDFEWLRSELERESKVVVP 90

Query: 58  PFPPKYYLAMTTAMAD----------ERRDQLEQYLQNVTMDP 90
           P P K +L       D          ER+  LEQ++  V   P
Sbjct: 91  PLPGKAFLRQLPFRGDDGIFDDNFIEERKQGLEQFINKVAGHP 133


>gi|139948432 adlican [Homo sapiens]
          Length = 2828

 Score = 29.3 bits (64), Expect = 7.4
 Identities = 21/43 (48%), Positives = 24/43 (55%), Gaps = 1/43 (2%)

Query: 291  SVGNNEISCCITLPDSQTQDIVFQMSRVKCWQVTFLGTLLDTD 333
            S    + S  ITLPDS T  I+  MS VK    T +GTLLD D
Sbjct: 1083 SESEGQESKSITLPDS-TLGIMSSMSPVKKPAETTVGTLLDKD 1124


>gi|221219020 NYD-SP11 protein [Homo sapiens]
          Length = 2873

 Score = 28.9 bits (63), Expect = 9.7
 Identities = 19/66 (28%), Positives = 36/66 (54%), Gaps = 2/66 (3%)

Query: 363  KQAFLLSSCLKKMISEKMVKLAAENTEMQIEVPEQSKSKKYHIQQSQQKDYSSFLSRKSK 422
            K+   L+  +K++  EKM  +  + T  + E PE S+ +K  + Q +Q+ +   LS + K
Sbjct: 1958 KEEKALNLEMKRLAEEKMRLVEGKETLSKGETPETSRQRK--MTQVEQELFERKLSLEEK 2015

Query: 423  IKIAKD 428
            I + +D
Sbjct: 2016 ILLHED 2021


>gi|194239633 solute carrier family 44, member 5 isoform B [Homo
           sapiens]
          Length = 717

 Score = 28.9 bits (63), Expect = 9.7
 Identities = 25/106 (23%), Positives = 49/106 (46%), Gaps = 6/106 (5%)

Query: 159 YFGLFLIRFGKEGKLSVVKKLADFE-LPYVSLGSSEVENCKVGLR-----KWYMAPSLDS 212
           YF LFL +    G + V+  L   + LP ++ G + +    V L       + +A    S
Sbjct: 610 YFVLFLGKLLVAGSIGVLAFLFFTQRLPVIAQGPASLNYYWVPLLTVIFGSYLIAHGFFS 669

Query: 213 VLMDCRVAVDLLYMQAIQDIEKGWAKPTQAQRQKLEAFQKEDSQTK 258
           V   C   + + +++ ++  +   A+P    +  L+ FQ+E+ QT+
Sbjct: 670 VYAMCVETIFICFLEDLERNDGSTARPYYVSQPLLKIFQEENPQTR 715


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.136    0.408 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,694,792
Number of Sequences: 37866
Number of extensions: 661099
Number of successful extensions: 1800
Number of sequences better than 10.0: 16
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 1788
Number of HSP's gapped (non-prelim): 17
length of query: 440
length of database: 18,247,518
effective HSP length: 105
effective length of query: 335
effective length of database: 14,271,588
effective search space: 4780981980
effective search space used: 4780981980
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.