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Search of human proteins with 221139879
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|221139879 G protein-coupled receptor 63 [Homo sapiens]
(419 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|221139879 G protein-coupled receptor 63 [Homo sapiens] 843 0.0
gi|13540557 G protein-coupled receptor 63 [Homo sapiens] 843 0.0
gi|31083315 G protein-coupled receptor 45 [Homo sapiens] 404 e-113
gi|94421462 serotonin 5-HT4 receptor isoform n [Homo sapiens] 123 3e-28
gi|94421460 serotonin 5-HT4 receptor isoform i [Homo sapiens] 123 3e-28
gi|94421456 serotonin 5-HT4 receptor isoform d [Homo sapiens] 123 3e-28
gi|94421454 serotonin 5-HT4 receptor isoform a [Homo sapiens] 123 3e-28
gi|41282074 serotonin 5-HT4 receptor isoform g [Homo sapiens] 123 3e-28
gi|11321563 serotonin 5-HT4 receptor isoform b [Homo sapiens] 123 3e-28
gi|94421458 serotonin 5-HT4 receptor isoform hb [Homo sapiens] 114 2e-25
gi|24476016 G protein-coupled receptor 161 isoform 2 [Homo sapiens] 109 4e-24
gi|197085610 histamine receptor H2 isoform 1 [Homo sapiens] 104 1e-22
gi|13435405 histamine receptor H2 isoform 2 [Homo sapiens] 104 1e-22
gi|7669546 tachykinin receptor 1 isoform short [Homo sapiens] 102 5e-22
gi|4507343 tachykinin receptor 1 isoform long [Homo sapiens] 102 5e-22
gi|5174593 melatonin receptor 1A [Homo sapiens] 102 5e-22
gi|4501969 adrenergic, beta-2-, receptor, surface [Homo sapiens] 100 2e-21
gi|10880131 5-hydroxytryptamine receptor 7 isoform b [Homo sapiens] 100 3e-21
gi|10880129 5-hydroxytryptamine receptor 7 isoform d [Homo sapiens] 100 3e-21
gi|4504547 5-hydroxytryptamine receptor 7 isoform a [Homo sapiens] 100 3e-21
gi|15150803 opsin 4 isoform 1 [Homo sapiens] 100 3e-21
gi|4758474 G protein-coupled receptor 10 [Homo sapiens] 100 4e-21
gi|4504545 5-hydroxytryptamine (serotonin) receptor 6 [Homo sapi... 97 3e-20
gi|110618256 trace amine associated receptor 9 [Homo sapiens] 97 4e-20
gi|10835175 5-hydroxytryptamine (serotonin) receptor 2A [Homo sa... 96 5e-20
gi|111118990 alpha-1A-adrenergic receptor isoform 4 [Homo sapiens] 96 6e-20
gi|111118992 alpha-1A-adrenergic receptor isoform 1 [Homo sapiens] 96 6e-20
gi|111118986 alpha-1A-adrenergic receptor isoform 2 [Homo sapiens] 96 6e-20
gi|111118988 alpha-1A-adrenergic receptor isoform 3 [Homo sapiens] 96 6e-20
gi|5174595 melatonin receptor 1B [Homo sapiens] 96 6e-20
>gi|221139879 G protein-coupled receptor 63 [Homo sapiens]
Length = 419
Score = 843 bits (2177), Expect = 0.0
Identities = 419/419 (100%), Positives = 419/419 (100%)
Query: 1 MVFSAVLTAFHTGTSNTTFVVYENTYMNITLPPPFQHPDLSPLLRYSFETMAPTGLSSLT 60
MVFSAVLTAFHTGTSNTTFVVYENTYMNITLPPPFQHPDLSPLLRYSFETMAPTGLSSLT
Sbjct: 1 MVFSAVLTAFHTGTSNTTFVVYENTYMNITLPPPFQHPDLSPLLRYSFETMAPTGLSSLT 60
Query: 61 VNSTAVPTTPAAFKSLNLPLQITLSAIMIFILFVSFLGNLVVCLMVYQKAAMRSAINILL 120
VNSTAVPTTPAAFKSLNLPLQITLSAIMIFILFVSFLGNLVVCLMVYQKAAMRSAINILL
Sbjct: 61 VNSTAVPTTPAAFKSLNLPLQITLSAIMIFILFVSFLGNLVVCLMVYQKAAMRSAINILL 120
Query: 121 ASLAFADMLLAVLNMPFALVTILTTRWIFGKFFCRVSAMFFWLFVIEGVAILLIISIDRF 180
ASLAFADMLLAVLNMPFALVTILTTRWIFGKFFCRVSAMFFWLFVIEGVAILLIISIDRF
Sbjct: 121 ASLAFADMLLAVLNMPFALVTILTTRWIFGKFFCRVSAMFFWLFVIEGVAILLIISIDRF 180
Query: 181 LIIVQRQDKLNPYRAKVLIAVSWATSFCVAFPLAVGNPDLQIPSRAPQCVFGYTTNPGYQ 240
LIIVQRQDKLNPYRAKVLIAVSWATSFCVAFPLAVGNPDLQIPSRAPQCVFGYTTNPGYQ
Sbjct: 181 LIIVQRQDKLNPYRAKVLIAVSWATSFCVAFPLAVGNPDLQIPSRAPQCVFGYTTNPGYQ 240
Query: 241 AYVILISLISFFIPFLVILYSFMGILNTLRHNALRIHSYPEGICLSQASKLGLMSLQRPF 300
AYVILISLISFFIPFLVILYSFMGILNTLRHNALRIHSYPEGICLSQASKLGLMSLQRPF
Sbjct: 241 AYVILISLISFFIPFLVILYSFMGILNTLRHNALRIHSYPEGICLSQASKLGLMSLQRPF 300
Query: 301 QMSIDMGFKTRAFTTILILFAVFIVCWAPFTTYSLVATFSKHFYYQHNFFEISTWLLWLC 360
QMSIDMGFKTRAFTTILILFAVFIVCWAPFTTYSLVATFSKHFYYQHNFFEISTWLLWLC
Sbjct: 301 QMSIDMGFKTRAFTTILILFAVFIVCWAPFTTYSLVATFSKHFYYQHNFFEISTWLLWLC 360
Query: 361 YLKSALNPLIYYWRIKKFHDACLDMMPKSFKFLPQLPGHTKRRIRPSAVYVCGEHRTVV 419
YLKSALNPLIYYWRIKKFHDACLDMMPKSFKFLPQLPGHTKRRIRPSAVYVCGEHRTVV
Sbjct: 361 YLKSALNPLIYYWRIKKFHDACLDMMPKSFKFLPQLPGHTKRRIRPSAVYVCGEHRTVV 419
>gi|13540557 G protein-coupled receptor 63 [Homo sapiens]
Length = 419
Score = 843 bits (2177), Expect = 0.0
Identities = 419/419 (100%), Positives = 419/419 (100%)
Query: 1 MVFSAVLTAFHTGTSNTTFVVYENTYMNITLPPPFQHPDLSPLLRYSFETMAPTGLSSLT 60
MVFSAVLTAFHTGTSNTTFVVYENTYMNITLPPPFQHPDLSPLLRYSFETMAPTGLSSLT
Sbjct: 1 MVFSAVLTAFHTGTSNTTFVVYENTYMNITLPPPFQHPDLSPLLRYSFETMAPTGLSSLT 60
Query: 61 VNSTAVPTTPAAFKSLNLPLQITLSAIMIFILFVSFLGNLVVCLMVYQKAAMRSAINILL 120
VNSTAVPTTPAAFKSLNLPLQITLSAIMIFILFVSFLGNLVVCLMVYQKAAMRSAINILL
Sbjct: 61 VNSTAVPTTPAAFKSLNLPLQITLSAIMIFILFVSFLGNLVVCLMVYQKAAMRSAINILL 120
Query: 121 ASLAFADMLLAVLNMPFALVTILTTRWIFGKFFCRVSAMFFWLFVIEGVAILLIISIDRF 180
ASLAFADMLLAVLNMPFALVTILTTRWIFGKFFCRVSAMFFWLFVIEGVAILLIISIDRF
Sbjct: 121 ASLAFADMLLAVLNMPFALVTILTTRWIFGKFFCRVSAMFFWLFVIEGVAILLIISIDRF 180
Query: 181 LIIVQRQDKLNPYRAKVLIAVSWATSFCVAFPLAVGNPDLQIPSRAPQCVFGYTTNPGYQ 240
LIIVQRQDKLNPYRAKVLIAVSWATSFCVAFPLAVGNPDLQIPSRAPQCVFGYTTNPGYQ
Sbjct: 181 LIIVQRQDKLNPYRAKVLIAVSWATSFCVAFPLAVGNPDLQIPSRAPQCVFGYTTNPGYQ 240
Query: 241 AYVILISLISFFIPFLVILYSFMGILNTLRHNALRIHSYPEGICLSQASKLGLMSLQRPF 300
AYVILISLISFFIPFLVILYSFMGILNTLRHNALRIHSYPEGICLSQASKLGLMSLQRPF
Sbjct: 241 AYVILISLISFFIPFLVILYSFMGILNTLRHNALRIHSYPEGICLSQASKLGLMSLQRPF 300
Query: 301 QMSIDMGFKTRAFTTILILFAVFIVCWAPFTTYSLVATFSKHFYYQHNFFEISTWLLWLC 360
QMSIDMGFKTRAFTTILILFAVFIVCWAPFTTYSLVATFSKHFYYQHNFFEISTWLLWLC
Sbjct: 301 QMSIDMGFKTRAFTTILILFAVFIVCWAPFTTYSLVATFSKHFYYQHNFFEISTWLLWLC 360
Query: 361 YLKSALNPLIYYWRIKKFHDACLDMMPKSFKFLPQLPGHTKRRIRPSAVYVCGEHRTVV 419
YLKSALNPLIYYWRIKKFHDACLDMMPKSFKFLPQLPGHTKRRIRPSAVYVCGEHRTVV
Sbjct: 361 YLKSALNPLIYYWRIKKFHDACLDMMPKSFKFLPQLPGHTKRRIRPSAVYVCGEHRTVV 419
>gi|31083315 G protein-coupled receptor 45 [Homo sapiens]
Length = 372
Score = 404 bits (1039), Expect = e-113
Identities = 190/344 (55%), Positives = 262/344 (76%)
Query: 76 LNLPLQITLSAIMIFILFVSFLGNLVVCLMVYQKAAMRSAINILLASLAFADMLLAVLNM 135
L PL+I+L+ +M+ + V FLGN VVC++VYQ+ AMRSAIN+LLA+LAF+D++L++ M
Sbjct: 29 LPAPLRISLAIVMLLMTVVGFLGNTVVCIIVYQRPAMRSAINLLLATLAFSDIMLSLCCM 88
Query: 136 PFALVTILTTRWIFGKFFCRVSAMFFWLFVIEGVAILLIISIDRFLIIVQRQDKLNPYRA 195
PF VT++T RW FG FCR+SA +W FV+EGVAILLIIS+DRFLIIVQRQDKLNP RA
Sbjct: 89 PFTAVTLITVRWHFGDHFCRLSATLYWFFVLEGVAILLIISVDRFLIIVQRQDKLNPRRA 148
Query: 196 KVLIAVSWATSFCVAFPLAVGNPDLQIPSRAPQCVFGYTTNPGYQAYVILISLISFFIPF 255
KV+IAVSW SFC+A P G +++P+RAPQCV GYT P +AYV+ + + FF PF
Sbjct: 149 KVIIAVSWVLSFCIAGPSLTGWTLVEVPARAPQCVLGYTELPADRAYVVTLVVAVFFAPF 208
Query: 256 LVILYSFMGILNTLRHNALRIHSYPEGICLSQASKLGLMSLQRPFQMSIDMGFKTRAFTT 315
V+L ++M ILNT+R NA+R+H+ + + L Q ++ GL LQR Q+S+D+ FKT+AFTT
Sbjct: 209 GVMLCAYMCILNTVRKNAVRVHNQSDSLDLRQLTRAGLRRLQRQQQVSVDLSFKTKAFTT 268
Query: 316 ILILFAVFIVCWAPFTTYSLVATFSKHFYYQHNFFEISTWLLWLCYLKSALNPLIYYWRI 375
ILILF F +CW P + YSL++ FS+ FY +F+ ST +LWL YLKS NP++Y WRI
Sbjct: 269 ILILFVGFSLCWLPHSVYSLLSVFSQRFYCGSSFYATSTCVLWLSYLKSVFNPIVYCWRI 328
Query: 376 KKFHDACLDMMPKSFKFLPQLPGHTKRRIRPSAVYVCGEHRTVV 419
KKF +AC++++P++F+ LP++P +RRI+PS VYVC E+++ V
Sbjct: 329 KKFREACIELLPQTFQILPKVPERIRRRIQPSTVYVCNENQSAV 372
>gi|94421462 serotonin 5-HT4 receptor isoform n [Homo sapiens]
Length = 359
Score = 123 bits (309), Expect = 3e-28
Identities = 89/321 (27%), Positives = 154/321 (47%), Gaps = 33/321 (10%)
Query: 81 QITLSAIMIFILFVSFLGNLVVCLMV-YQKAAMRSAINILLASLAFADMLLAVLNMPFAL 139
++ L + ++ ++ LGNL+V + V + + + N + SLAFAD+L++VL MPF
Sbjct: 19 KVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGA 78
Query: 140 VTILTTRWIFGKFFCRVSAMFFWLFVIEGVAILLIISIDRFLII----VQRQDKLNPYRA 195
+ ++ WI+G+ FC V L + L IS+DR+ I + ++K+ P R
Sbjct: 79 IELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRI 138
Query: 196 KVLIAVSWATSFCVAF-PLAVGNPDLQIPSRAPQCVFGYTTNPGY------QAYVILISL 248
+++ W ++F P+ G ++ I + F +N Y + Y I S+
Sbjct: 139 ALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNKPYAITCSV 198
Query: 249 ISFFIPFLVILYSFMGILNTLRHNALRIHSYPEGICLSQASKLGLMSLQRPFQMSID--- 305
++F+IPFL+++ ++ I T + +A +I + G S RP S D
Sbjct: 199 VAFYIPFLLMVLAYYRIYVTAKEHAHQI---------QMLQRAGASSESRP--QSADQHS 247
Query: 306 ---MGFKTRAFTTILILFAVFIVCWAPFTTYSLVATFSKHFYYQHNFFEISTWLLWLCYL 362
M +T+A T+ I+ F +CWAPF ++V F + ++ T LWL Y+
Sbjct: 248 THRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPG----QVWTAFLWLGYI 303
Query: 363 KSALNPLIYYWRIKKFHDACL 383
S LNP +Y + K F A L
Sbjct: 304 NSGLNPFLYAFLNKSFRRAFL 324
>gi|94421460 serotonin 5-HT4 receptor isoform i [Homo sapiens]
Length = 428
Score = 123 bits (309), Expect = 3e-28
Identities = 89/321 (27%), Positives = 154/321 (47%), Gaps = 33/321 (10%)
Query: 81 QITLSAIMIFILFVSFLGNLVVCLMV-YQKAAMRSAINILLASLAFADMLLAVLNMPFAL 139
++ L + ++ ++ LGNL+V + V + + + N + SLAFAD+L++VL MPF
Sbjct: 19 KVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGA 78
Query: 140 VTILTTRWIFGKFFCRVSAMFFWLFVIEGVAILLIISIDRFLII----VQRQDKLNPYRA 195
+ ++ WI+G+ FC V L + L IS+DR+ I + ++K+ P R
Sbjct: 79 IELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRI 138
Query: 196 KVLIAVSWATSFCVAF-PLAVGNPDLQIPSRAPQCVFGYTTNPGY------QAYVILISL 248
+++ W ++F P+ G ++ I + F +N Y + Y I S+
Sbjct: 139 ALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNKPYAITCSV 198
Query: 249 ISFFIPFLVILYSFMGILNTLRHNALRIHSYPEGICLSQASKLGLMSLQRPFQMSID--- 305
++F+IPFL+++ ++ I T + +A +I + G S RP S D
Sbjct: 199 VAFYIPFLLMVLAYYRIYVTAKEHAHQI---------QMLQRAGASSESRP--QSADQHS 247
Query: 306 ---MGFKTRAFTTILILFAVFIVCWAPFTTYSLVATFSKHFYYQHNFFEISTWLLWLCYL 362
M +T+A T+ I+ F +CWAPF ++V F + ++ T LWL Y+
Sbjct: 248 THRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPG----QVWTAFLWLGYI 303
Query: 363 KSALNPLIYYWRIKKFHDACL 383
S LNP +Y + K F A L
Sbjct: 304 NSGLNPFLYAFLNKSFRRAFL 324
>gi|94421456 serotonin 5-HT4 receptor isoform d [Homo sapiens]
Length = 360
Score = 123 bits (309), Expect = 3e-28
Identities = 89/321 (27%), Positives = 154/321 (47%), Gaps = 33/321 (10%)
Query: 81 QITLSAIMIFILFVSFLGNLVVCLMV-YQKAAMRSAINILLASLAFADMLLAVLNMPFAL 139
++ L + ++ ++ LGNL+V + V + + + N + SLAFAD+L++VL MPF
Sbjct: 19 KVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGA 78
Query: 140 VTILTTRWIFGKFFCRVSAMFFWLFVIEGVAILLIISIDRFLII----VQRQDKLNPYRA 195
+ ++ WI+G+ FC V L + L IS+DR+ I + ++K+ P R
Sbjct: 79 IELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRI 138
Query: 196 KVLIAVSWATSFCVAF-PLAVGNPDLQIPSRAPQCVFGYTTNPGY------QAYVILISL 248
+++ W ++F P+ G ++ I + F +N Y + Y I S+
Sbjct: 139 ALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNKPYAITCSV 198
Query: 249 ISFFIPFLVILYSFMGILNTLRHNALRIHSYPEGICLSQASKLGLMSLQRPFQMSID--- 305
++F+IPFL+++ ++ I T + +A +I + G S RP S D
Sbjct: 199 VAFYIPFLLMVLAYYRIYVTAKEHAHQI---------QMLQRAGASSESRP--QSADQHS 247
Query: 306 ---MGFKTRAFTTILILFAVFIVCWAPFTTYSLVATFSKHFYYQHNFFEISTWLLWLCYL 362
M +T+A T+ I+ F +CWAPF ++V F + ++ T LWL Y+
Sbjct: 248 THRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPG----QVWTAFLWLGYI 303
Query: 363 KSALNPLIYYWRIKKFHDACL 383
S LNP +Y + K F A L
Sbjct: 304 NSGLNPFLYAFLNKSFRRAFL 324
>gi|94421454 serotonin 5-HT4 receptor isoform a [Homo sapiens]
Length = 387
Score = 123 bits (309), Expect = 3e-28
Identities = 89/321 (27%), Positives = 154/321 (47%), Gaps = 33/321 (10%)
Query: 81 QITLSAIMIFILFVSFLGNLVVCLMV-YQKAAMRSAINILLASLAFADMLLAVLNMPFAL 139
++ L + ++ ++ LGNL+V + V + + + N + SLAFAD+L++VL MPF
Sbjct: 19 KVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGA 78
Query: 140 VTILTTRWIFGKFFCRVSAMFFWLFVIEGVAILLIISIDRFLII----VQRQDKLNPYRA 195
+ ++ WI+G+ FC V L + L IS+DR+ I + ++K+ P R
Sbjct: 79 IELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRI 138
Query: 196 KVLIAVSWATSFCVAF-PLAVGNPDLQIPSRAPQCVFGYTTNPGY------QAYVILISL 248
+++ W ++F P+ G ++ I + F +N Y + Y I S+
Sbjct: 139 ALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNKPYAITCSV 198
Query: 249 ISFFIPFLVILYSFMGILNTLRHNALRIHSYPEGICLSQASKLGLMSLQRPFQMSID--- 305
++F+IPFL+++ ++ I T + +A +I + G S RP S D
Sbjct: 199 VAFYIPFLLMVLAYYRIYVTAKEHAHQI---------QMLQRAGASSESRP--QSADQHS 247
Query: 306 ---MGFKTRAFTTILILFAVFIVCWAPFTTYSLVATFSKHFYYQHNFFEISTWLLWLCYL 362
M +T+A T+ I+ F +CWAPF ++V F + ++ T LWL Y+
Sbjct: 248 THRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPG----QVWTAFLWLGYI 303
Query: 363 KSALNPLIYYWRIKKFHDACL 383
S LNP +Y + K F A L
Sbjct: 304 NSGLNPFLYAFLNKSFRRAFL 324
>gi|41282074 serotonin 5-HT4 receptor isoform g [Homo sapiens]
Length = 378
Score = 123 bits (309), Expect = 3e-28
Identities = 89/321 (27%), Positives = 154/321 (47%), Gaps = 33/321 (10%)
Query: 81 QITLSAIMIFILFVSFLGNLVVCLMV-YQKAAMRSAINILLASLAFADMLLAVLNMPFAL 139
++ L + ++ ++ LGNL+V + V + + + N + SLAFAD+L++VL MPF
Sbjct: 19 KVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGA 78
Query: 140 VTILTTRWIFGKFFCRVSAMFFWLFVIEGVAILLIISIDRFLII----VQRQDKLNPYRA 195
+ ++ WI+G+ FC V L + L IS+DR+ I + ++K+ P R
Sbjct: 79 IELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRI 138
Query: 196 KVLIAVSWATSFCVAF-PLAVGNPDLQIPSRAPQCVFGYTTNPGY------QAYVILISL 248
+++ W ++F P+ G ++ I + F +N Y + Y I S+
Sbjct: 139 ALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNKPYAITCSV 198
Query: 249 ISFFIPFLVILYSFMGILNTLRHNALRIHSYPEGICLSQASKLGLMSLQRPFQMSID--- 305
++F+IPFL+++ ++ I T + +A +I + G S RP S D
Sbjct: 199 VAFYIPFLLMVLAYYRIYVTAKEHAHQI---------QMLQRAGASSESRP--QSADQHS 247
Query: 306 ---MGFKTRAFTTILILFAVFIVCWAPFTTYSLVATFSKHFYYQHNFFEISTWLLWLCYL 362
M +T+A T+ I+ F +CWAPF ++V F + ++ T LWL Y+
Sbjct: 248 THRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPG----QVWTAFLWLGYI 303
Query: 363 KSALNPLIYYWRIKKFHDACL 383
S LNP +Y + K F A L
Sbjct: 304 NSGLNPFLYAFLNKSFRRAFL 324
>gi|11321563 serotonin 5-HT4 receptor isoform b [Homo sapiens]
Length = 388
Score = 123 bits (309), Expect = 3e-28
Identities = 89/321 (27%), Positives = 154/321 (47%), Gaps = 33/321 (10%)
Query: 81 QITLSAIMIFILFVSFLGNLVVCLMV-YQKAAMRSAINILLASLAFADMLLAVLNMPFAL 139
++ L + ++ ++ LGNL+V + V + + + N + SLAFAD+L++VL MPF
Sbjct: 19 KVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGA 78
Query: 140 VTILTTRWIFGKFFCRVSAMFFWLFVIEGVAILLIISIDRFLII----VQRQDKLNPYRA 195
+ ++ WI+G+ FC V L + L IS+DR+ I + ++K+ P R
Sbjct: 79 IELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRI 138
Query: 196 KVLIAVSWATSFCVAF-PLAVGNPDLQIPSRAPQCVFGYTTNPGY------QAYVILISL 248
+++ W ++F P+ G ++ I + F +N Y + Y I S+
Sbjct: 139 ALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNKPYAITCSV 198
Query: 249 ISFFIPFLVILYSFMGILNTLRHNALRIHSYPEGICLSQASKLGLMSLQRPFQMSID--- 305
++F+IPFL+++ ++ I T + +A +I + G S RP S D
Sbjct: 199 VAFYIPFLLMVLAYYRIYVTAKEHAHQI---------QMLQRAGASSESRP--QSADQHS 247
Query: 306 ---MGFKTRAFTTILILFAVFIVCWAPFTTYSLVATFSKHFYYQHNFFEISTWLLWLCYL 362
M +T+A T+ I+ F +CWAPF ++V F + ++ T LWL Y+
Sbjct: 248 THRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPG----QVWTAFLWLGYI 303
Query: 363 KSALNPLIYYWRIKKFHDACL 383
S LNP +Y + K F A L
Sbjct: 304 NSGLNPFLYAFLNKSFRRAFL 324
>gi|94421458 serotonin 5-HT4 receptor isoform hb [Homo sapiens]
Length = 402
Score = 114 bits (285), Expect = 2e-25
Identities = 90/340 (26%), Positives = 154/340 (45%), Gaps = 57/340 (16%)
Query: 81 QITLSAIMIFILFVSFLGNLVVCLMV-YQKAAMRSAINILLASLAFADMLLAVLNMPFAL 139
++ L + ++ ++ LGNL+V + V + + + N + SLAFAD+L++VL MPF
Sbjct: 19 KVVLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGA 78
Query: 140 VTILTTRWIFGKFFCRVSAMFFWLFVIEGVAILLIISIDRFLII----VQRQDKLNPYRA 195
+ ++ WI+G+ FC V L + L IS+DR+ I + ++K+ P R
Sbjct: 79 IELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRI 138
Query: 196 KVLIAVSWATSFCVAF-PLAVGNPDLQI-------------------------PSRAPQC 229
+++ W ++F P+ G ++ I S + C
Sbjct: 139 ALMLGGCWVIPTFISFLPIMQGWNNIGIIDLERSLNQGLGQDFHAIEKRKFNQNSNSTYC 198
Query: 230 VFGYTTNPGYQAYVILISLISFFIPFLVILYSFMGILNTLRHNALRIHSYPEGICLSQAS 289
VF + Y I S+++F+IPFL+++ ++ I T + +A +I
Sbjct: 199 VFMVN-----KPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQI---------QMLQ 244
Query: 290 KLGLMSLQRPFQMSID------MGFKTRAFTTILILFAVFIVCWAPFTTYSLVATFSKHF 343
+ G S RP S D M +T+A T+ I+ F +CWAPF ++V F +
Sbjct: 245 RAGASSESRP--QSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYT 302
Query: 344 YYQHNFFEISTWLLWLCYLKSALNPLIYYWRIKKFHDACL 383
++ T LWL Y+ S LNP +Y + K F A L
Sbjct: 303 VPG----QVWTAFLWLGYINSGLNPFLYAFLNKSFRRAFL 338
>gi|24476016 G protein-coupled receptor 161 isoform 2 [Homo sapiens]
Length = 529
Score = 109 bits (273), Expect = 4e-24
Identities = 79/300 (26%), Positives = 136/300 (45%), Gaps = 22/300 (7%)
Query: 86 AIMIFILFVSFLGNLVVCLMVYQKAAMRSAINILLASLAFADMLLAVLNMPFALVTILTT 145
AI++ +FV LGNLV+ + +Y+K+ + + N + SL ++ LL+VL +PF + + +
Sbjct: 33 AIIVITIFVC-LGNLVIVVTLYKKSYLLTLSNKFVFSLTLSNFLLSVLVLPFVVTSSIRR 91
Query: 146 RWIFGKFFCRVSAMFFWLFVIEGVAILLIISIDRFLIIVQRQ---DKLNPYRAKVLIAVS 202
WIFG +C SA+ + L + L +I+IDR+ ++ K+ RA + +
Sbjct: 92 EWIFGVVWCNFSALLYLLISSASMLTLGVIAIDRYYAVLYPMVYPMKITGNRAVMALVYI 151
Query: 203 WATSFCVAFPLAVGNPDLQIPSRAPQCVFGYTTNPGYQAYVILISLISFFIPFLVILYSF 262
W S P G ++ CV + PGY A+ + PFLV+L +
Sbjct: 152 WLHSLIGCLPPLFGWSSVEFDEFKWMCVAAWHREPGYTAF---WQIWCALFPFLVMLVCY 208
Query: 263 MGILNTLRHNALRIHSYPEGICLSQASKLGLM----------SLQRPFQMSIDMGFKTRA 312
I R A ++H I A + G S + FQ + + +A
Sbjct: 209 GFIFRVARVKARKVHCGTVVIVEEDAQRTGRKNSSTSTSSSGSRRNAFQGVVYSANQCKA 268
Query: 313 FTTILILFAVFIVCWAPFTTYSLVATFSKHFYYQHNFF-EISTWLLWLCYLKSALNPLIY 371
TIL++ F+V W P+ +V S+ + + + + TW WL + + +PLIY
Sbjct: 269 LITILVVLGAFMVTWGPY----MVVIASEALWGKSSVSPSLETWATWLSFASAVCHPLIY 324
>gi|197085610 histamine receptor H2 isoform 1 [Homo sapiens]
Length = 397
Score = 104 bits (260), Expect = 1e-22
Identities = 83/331 (25%), Positives = 149/331 (45%), Gaps = 53/331 (16%)
Query: 51 MAPTGL-SSLTVNSTAVPTTPAAFKSLNLPLQITLSAIMIFILFVSFLGNLVVCLMVYQK 109
MAP G SS ++STA +IT++ ++ ++ ++ GN+VVCL V
Sbjct: 1 MAPNGTASSFCLDSTAC--------------KITITVVLAVLILITVAGNVVVCLAVGLN 46
Query: 110 AAMRSAINILLASLAFADMLLAVLNMPFALVTILTTRWIFGKFFCRVSAMFFWLFVIEGV 169
+R+ N + SLA D+LL +L +PF+ + L+ +W FGK FC + + +
Sbjct: 47 RRLRNLTNCFIVSLAITDLLLGLLVLPFSAIYQLSCKWSFGKVFCNIYTSLDVMLCTASI 106
Query: 170 AILLIISIDRFLIIVQRQDKLNPYRAKVL-----IAVSWATSFCVAFPLAVGNPDLQIPS 224
L +IS+DR+ + ++P R VL +A+S + ++ L+ + L S
Sbjct: 107 LNLFMISLDRYCAV------MDPLRYPVLVTPVRVAISLVLIWVISITLSFLSIHLGWNS 160
Query: 225 RAPQCVFGYTTN----PGYQAYVILISLISFFIPFLVILYSFMGILNTLRHNALRIHSYP 280
R +TT+ + Y ++ L++F++P L++ ++ I R A RI+
Sbjct: 161 RNETSKGNHTTSKCKVQVNEVYGLVDGLVTFYLPLLIMCITYYRIFKVARDQAKRINH-- 218
Query: 281 EGICLSQASKLGLMSLQRPFQMSIDMGFKTRAFTTILILFAVFIVCWAPFTTYSLVATFS 340
I +A+ + + +A T+ + FI+CW P+ T +
Sbjct: 219 --ISSWKAATIR----------------EHKATVTLAAVMGAFIICWFPYFTAFVYRGLR 260
Query: 341 KHFYYQHNFFEISTWLLWLCYLKSALNPLIY 371
+ +LWL Y SALNP++Y
Sbjct: 261 GDDAINE---VLEAIVLWLGYANSALNPILY 288
>gi|13435405 histamine receptor H2 isoform 2 [Homo sapiens]
Length = 359
Score = 104 bits (260), Expect = 1e-22
Identities = 83/331 (25%), Positives = 149/331 (45%), Gaps = 53/331 (16%)
Query: 51 MAPTGL-SSLTVNSTAVPTTPAAFKSLNLPLQITLSAIMIFILFVSFLGNLVVCLMVYQK 109
MAP G SS ++STA +IT++ ++ ++ ++ GN+VVCL V
Sbjct: 1 MAPNGTASSFCLDSTAC--------------KITITVVLAVLILITVAGNVVVCLAVGLN 46
Query: 110 AAMRSAINILLASLAFADMLLAVLNMPFALVTILTTRWIFGKFFCRVSAMFFWLFVIEGV 169
+R+ N + SLA D+LL +L +PF+ + L+ +W FGK FC + + +
Sbjct: 47 RRLRNLTNCFIVSLAITDLLLGLLVLPFSAIYQLSCKWSFGKVFCNIYTSLDVMLCTASI 106
Query: 170 AILLIISIDRFLIIVQRQDKLNPYRAKVL-----IAVSWATSFCVAFPLAVGNPDLQIPS 224
L +IS+DR+ + ++P R VL +A+S + ++ L+ + L S
Sbjct: 107 LNLFMISLDRYCAV------MDPLRYPVLVTPVRVAISLVLIWVISITLSFLSIHLGWNS 160
Query: 225 RAPQCVFGYTTN----PGYQAYVILISLISFFIPFLVILYSFMGILNTLRHNALRIHSYP 280
R +TT+ + Y ++ L++F++P L++ ++ I R A RI+
Sbjct: 161 RNETSKGNHTTSKCKVQVNEVYGLVDGLVTFYLPLLIMCITYYRIFKVARDQAKRINH-- 218
Query: 281 EGICLSQASKLGLMSLQRPFQMSIDMGFKTRAFTTILILFAVFIVCWAPFTTYSLVATFS 340
I +A+ + + +A T+ + FI+CW P+ T +
Sbjct: 219 --ISSWKAATIR----------------EHKATVTLAAVMGAFIICWFPYFTAFVYRGLR 260
Query: 341 KHFYYQHNFFEISTWLLWLCYLKSALNPLIY 371
+ +LWL Y SALNP++Y
Sbjct: 261 GDDAINE---VLEAIVLWLGYANSALNPILY 288
>gi|7669546 tachykinin receptor 1 isoform short [Homo sapiens]
Length = 311
Score = 102 bits (255), Expect = 5e-22
Identities = 73/296 (24%), Positives = 133/296 (44%), Gaps = 26/296 (8%)
Query: 81 QITL-SAIMIFILFVSFLGNLVVCLMVYQKAAMRSAINILLASLAFADMLLAVLNMPFAL 139
QI L +A I+ S +GN+VV ++ MR+ N L +LAFA+ +A N
Sbjct: 31 QIVLWAAAYTVIVVTSVVGNVVVMWIILAHKRMRTVTNYFLVNLAFAEASMAAFNTVVNF 90
Query: 140 VTILTTRWIFGKFFCRVSAMFFWLFVIEGVAILLIISIDRFLIIVQ-RQDKLNPYRAKVL 198
+ W +G F+C+ F V + + ++ DR++ I+ Q +L+ KV+
Sbjct: 91 TYAVHNEWYYGLFYCKFHNFFPIAAVFASIYSMTAVAFDRYMAIIHPLQPRLSATATKVV 150
Query: 199 IAVSWATSFCVAFPLAVGNPDLQIPSRAPQCVFGYTTNPG---YQAYVILISLISFFIPF 255
I V W + +AFP + +PSR C+ + +P + Y I ++++ +F+P
Sbjct: 151 ICVIWVLALLLAFPQGYYSTTETMPSRV-VCMIEWPEHPNKIYEKVYHICVTVLIYFLPL 209
Query: 256 LVILYSFMGILNTLRHNALRIHSYPEGICLSQASKLGLMSLQRPFQMSIDMGFKTRAFTT 315
LVI Y++ + GI L + G S + Q+S K +
Sbjct: 210 LVIGYAYTVV----------------GITLWASEIPGDSSDRYHEQVSA----KRKVVKM 249
Query: 316 ILILFAVFIVCWAPFTTYSLVATFSKHFYYQHNFFEISTWLLWLCYLKSALNPLIY 371
++++ F +CW PF + L+ + Y + ++ ++WL + NP+IY
Sbjct: 250 MIVVVCTFAICWLPFHIFFLLPYINPDLYLKKFIQQVYLAIMWLAMSSTMYNPIIY 305
>gi|4507343 tachykinin receptor 1 isoform long [Homo sapiens]
Length = 407
Score = 102 bits (255), Expect = 5e-22
Identities = 73/296 (24%), Positives = 133/296 (44%), Gaps = 26/296 (8%)
Query: 81 QITL-SAIMIFILFVSFLGNLVVCLMVYQKAAMRSAINILLASLAFADMLLAVLNMPFAL 139
QI L +A I+ S +GN+VV ++ MR+ N L +LAFA+ +A N
Sbjct: 31 QIVLWAAAYTVIVVTSVVGNVVVMWIILAHKRMRTVTNYFLVNLAFAEASMAAFNTVVNF 90
Query: 140 VTILTTRWIFGKFFCRVSAMFFWLFVIEGVAILLIISIDRFLIIVQ-RQDKLNPYRAKVL 198
+ W +G F+C+ F V + + ++ DR++ I+ Q +L+ KV+
Sbjct: 91 TYAVHNEWYYGLFYCKFHNFFPIAAVFASIYSMTAVAFDRYMAIIHPLQPRLSATATKVV 150
Query: 199 IAVSWATSFCVAFPLAVGNPDLQIPSRAPQCVFGYTTNPG---YQAYVILISLISFFIPF 255
I V W + +AFP + +PSR C+ + +P + Y I ++++ +F+P
Sbjct: 151 ICVIWVLALLLAFPQGYYSTTETMPSRV-VCMIEWPEHPNKIYEKVYHICVTVLIYFLPL 209
Query: 256 LVILYSFMGILNTLRHNALRIHSYPEGICLSQASKLGLMSLQRPFQMSIDMGFKTRAFTT 315
LVI Y++ + GI L + G S + Q+S K +
Sbjct: 210 LVIGYAYTVV----------------GITLWASEIPGDSSDRYHEQVSA----KRKVVKM 249
Query: 316 ILILFAVFIVCWAPFTTYSLVATFSKHFYYQHNFFEISTWLLWLCYLKSALNPLIY 371
++++ F +CW PF + L+ + Y + ++ ++WL + NP+IY
Sbjct: 250 MIVVVCTFAICWLPFHIFFLLPYINPDLYLKKFIQQVYLAIMWLAMSSTMYNPIIY 305
>gi|5174593 melatonin receptor 1A [Homo sapiens]
Length = 350
Score = 102 bits (255), Expect = 5e-22
Identities = 79/300 (26%), Positives = 131/300 (43%), Gaps = 38/300 (12%)
Query: 80 LQITLSAIMIFILFVSFLGNLVVCLMVYQKAAMRSAINILLASLAFADMLLAVLNMPFAL 139
L L+ ++IF + V LGNL+V L VY+ +R+A NI + SLA AD+++A+ P L
Sbjct: 26 LASALACVLIFTIVVDILGNLLVILSVYRNKKLRNAGNIFVVSLAVADLVVAIYPYPLVL 85
Query: 140 VTILTTRWIFGKFFCRVSAMFFWLFVIEGVAILLIISIDRFLIIVQ--RQDKL-NPYRAK 196
++I W G C+VS L VI + + I+I+R+ I + DKL + +
Sbjct: 86 MSIFNNGWNLGYLHCQVSGFLMGLSVIGSIFNITGIAINRYCYICHSLKYDKLYSSKNSL 145
Query: 197 VLIAVSWATSFCVAFP-LAVGNPDLQIPSRAPQCVFGYTTNPGYQAYVILISLISFFIPF 255
+ + W + P L G LQ R C F + + AY I + + F +P
Sbjct: 146 CYVLLIWLLTLAAVLPNLRAGT--LQYDPRIYSCTFAQSVS---SAYTIAVVVFHFLVPM 200
Query: 256 LVILYSFMGILNTLRHNALRIHSYPEGICLSQASKLGLMSLQRPFQMSIDMGFKTRAFTT 315
+++++ ++ I + R+ P+ ++P D R F T
Sbjct: 201 IIVIFCYLRIWILVLQVRQRVK--PD---------------RKPKLKPQDF----RNFVT 239
Query: 316 ILILFAVFIVCWAPFTTYSLVATFSKHFYYQHNFFEISTWLL----WLCYLKSALNPLIY 371
+ ++F +F +CWAP L I WL ++ Y S LN +IY
Sbjct: 240 MFVVFVLFAICWAPLNFIGLAVASDPASMVP----RIPEWLFVASYYMAYFNSCLNAIIY 295
>gi|4501969 adrenergic, beta-2-, receptor, surface [Homo sapiens]
Length = 413
Score = 100 bits (249), Expect = 2e-21
Identities = 79/304 (25%), Positives = 141/304 (46%), Gaps = 29/304 (9%)
Query: 82 ITLSAIMIFILFVSFLGNLVVCLMVYQKAAMRSAINILLASLAFADMLLAVLNMPFALVT 141
I +S I++ I+F GN++V + + +++ N + SLA AD+++ + +PF
Sbjct: 38 IVMSLIVLAIVF----GNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGAAH 93
Query: 142 ILTTRWIFGKFFCRVSAMFFWLFVIEGVAILLIISIDRFLIIV---QRQDKLNPYRAKVL 198
IL W FG F+C L V + L +I++DR+ I + Q L +A+V+
Sbjct: 94 ILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVI 153
Query: 199 IAVSWATSFCVAF-PLAV----GNPDLQIPSRAPQCVFGYTTNPGYQAYVILISLISFFI 253
I + W S +F P+ + I A + + TN QAY I S++SF++
Sbjct: 154 ILMVWIVSGLTSFLPIQMHWYRATHQEAINCYANETCCDFFTN---QAYAIASSIVSFYV 210
Query: 254 PFLVILYSFMGILNTLRHNALRIHSYPEGIC----LSQASKLGLM--SLQRPFQMSIDMG 307
P +++++ + + + +I EG LSQ + G L+R + +
Sbjct: 211 PLVIMVFVYSRVFQEAKRQLQKIDK-SEGRFHVQNLSQVEQDGRTGHGLRRSSKFCLK-- 267
Query: 308 FKTRAFTTILILFAVFIVCWAPFTTYSLVATFSKHFYYQHNFFEISTWLLWLCYLKSALN 367
+ +A T+ I+ F +CW PF ++V + + E+ L W+ Y+ S N
Sbjct: 268 -EHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIRK----EVYILLNWIGYVNSGFN 322
Query: 368 PLIY 371
PLIY
Sbjct: 323 PLIY 326
>gi|10880131 5-hydroxytryptamine receptor 7 isoform b [Homo sapiens]
Length = 432
Score = 100 bits (248), Expect = 3e-21
Identities = 90/319 (28%), Positives = 142/319 (44%), Gaps = 43/319 (13%)
Query: 81 QITLSAIMIFILFVSFLGNLVVCLMVYQKAAMRSAINILLASLAFADMLLAVLNMPFALV 140
++ + +I+ I ++ GN +V + V +R N L+ SLA AD+ +AV MPF V
Sbjct: 81 KVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQPSNYLIVSLALADLSVAVAVMPFVSV 140
Query: 141 T-ILTTRWIFGKFFCRVSAMFFWLFVIEGVAILLIISIDRFLIIVQ------RQDKLNPY 193
T ++ +WIFG FFC V + + L +ISIDR+L I + RQ+
Sbjct: 141 TDLIGGKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQN--GKC 198
Query: 194 RAKVLIAVSWATSFCVAFPLAVGNPDLQIPSRAPQCV----FGYTTNPGYQAYVILISLI 249
AK++++V W S + P G Q + C+ FGYT I + +
Sbjct: 199 MAKMILSV-WLLSASITLPPLFG--WAQNVNDDKVCLISQDFGYT---------IYSTAV 246
Query: 250 SFFIPFLVILYSFMGILNTLRHNALRIHSYPEGICLSQASKL---GLMSLQRPFQMSIDM 306
+F+IP V+L+ + I R +A + H +P + S + G++ LQ+ + ++
Sbjct: 247 AFYIPMSVMLFMYYQIYKAARKSAAK-HKFPGFPRVEPDSVIALNGIVKLQKEVEECANL 305
Query: 307 G------------FK--TRAFTTILILFAVFIVCWAPFTTYSLVATFSKHFYYQHNFFEI 352
FK +A TT+ I+ F VCW PF S F +
Sbjct: 306 SRLLKHERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCSCIPLWV 365
Query: 353 STWLLWLCYLKSALNPLIY 371
LWL Y S +NP IY
Sbjct: 366 ERTFLWLGYANSLINPFIY 384
>gi|10880129 5-hydroxytryptamine receptor 7 isoform d [Homo sapiens]
Length = 479
Score = 100 bits (248), Expect = 3e-21
Identities = 90/319 (28%), Positives = 142/319 (44%), Gaps = 43/319 (13%)
Query: 81 QITLSAIMIFILFVSFLGNLVVCLMVYQKAAMRSAINILLASLAFADMLLAVLNMPFALV 140
++ + +I+ I ++ GN +V + V +R N L+ SLA AD+ +AV MPF V
Sbjct: 81 KVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQPSNYLIVSLALADLSVAVAVMPFVSV 140
Query: 141 T-ILTTRWIFGKFFCRVSAMFFWLFVIEGVAILLIISIDRFLIIVQ------RQDKLNPY 193
T ++ +WIFG FFC V + + L +ISIDR+L I + RQ+
Sbjct: 141 TDLIGGKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQN--GKC 198
Query: 194 RAKVLIAVSWATSFCVAFPLAVGNPDLQIPSRAPQCV----FGYTTNPGYQAYVILISLI 249
AK++++V W S + P G Q + C+ FGYT I + +
Sbjct: 199 MAKMILSV-WLLSASITLPPLFG--WAQNVNDDKVCLISQDFGYT---------IYSTAV 246
Query: 250 SFFIPFLVILYSFMGILNTLRHNALRIHSYPEGICLSQASKL---GLMSLQRPFQMSIDM 306
+F+IP V+L+ + I R +A + H +P + S + G++ LQ+ + ++
Sbjct: 247 AFYIPMSVMLFMYYQIYKAARKSAAK-HKFPGFPRVEPDSVIALNGIVKLQKEVEECANL 305
Query: 307 G------------FK--TRAFTTILILFAVFIVCWAPFTTYSLVATFSKHFYYQHNFFEI 352
FK +A TT+ I+ F VCW PF S F +
Sbjct: 306 SRLLKHERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCSCIPLWV 365
Query: 353 STWLLWLCYLKSALNPLIY 371
LWL Y S +NP IY
Sbjct: 366 ERTFLWLGYANSLINPFIY 384
>gi|4504547 5-hydroxytryptamine receptor 7 isoform a [Homo sapiens]
Length = 445
Score = 100 bits (248), Expect = 3e-21
Identities = 90/319 (28%), Positives = 142/319 (44%), Gaps = 43/319 (13%)
Query: 81 QITLSAIMIFILFVSFLGNLVVCLMVYQKAAMRSAINILLASLAFADMLLAVLNMPFALV 140
++ + +I+ I ++ GN +V + V +R N L+ SLA AD+ +AV MPF V
Sbjct: 81 KVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQPSNYLIVSLALADLSVAVAVMPFVSV 140
Query: 141 T-ILTTRWIFGKFFCRVSAMFFWLFVIEGVAILLIISIDRFLIIVQ------RQDKLNPY 193
T ++ +WIFG FFC V + + L +ISIDR+L I + RQ+
Sbjct: 141 TDLIGGKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQN--GKC 198
Query: 194 RAKVLIAVSWATSFCVAFPLAVGNPDLQIPSRAPQCV----FGYTTNPGYQAYVILISLI 249
AK++++V W S + P G Q + C+ FGYT I + +
Sbjct: 199 MAKMILSV-WLLSASITLPPLFG--WAQNVNDDKVCLISQDFGYT---------IYSTAV 246
Query: 250 SFFIPFLVILYSFMGILNTLRHNALRIHSYPEGICLSQASKL---GLMSLQRPFQMSIDM 306
+F+IP V+L+ + I R +A + H +P + S + G++ LQ+ + ++
Sbjct: 247 AFYIPMSVMLFMYYQIYKAARKSAAK-HKFPGFPRVEPDSVIALNGIVKLQKEVEECANL 305
Query: 307 G------------FK--TRAFTTILILFAVFIVCWAPFTTYSLVATFSKHFYYQHNFFEI 352
FK +A TT+ I+ F VCW PF S F +
Sbjct: 306 SRLLKHERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCSCIPLWV 365
Query: 353 STWLLWLCYLKSALNPLIY 371
LWL Y S +NP IY
Sbjct: 366 ERTFLWLGYANSLINPFIY 384
>gi|15150803 opsin 4 isoform 1 [Homo sapiens]
Length = 478
Score = 100 bits (248), Expect = 3e-21
Identities = 93/394 (23%), Positives = 166/394 (42%), Gaps = 34/394 (8%)
Query: 32 PPPFQHPD-LSPLLRYSFETMAPTGLSSLTVNSTAVPTTPAAFKSLNLPL---------Q 81
P P Q P ++ S+ + + +SSL + PT P + + +PL
Sbjct: 11 PSPTQEPSCMATPAPPSWWDSSQSSISSLGRLPSISPTAPGTWAAAWVPLPTVDVPDHAH 70
Query: 82 ITLSAIMIFILFVSFLGNLVVCLMVYQKAAMRSAINILLASLAFADMLLAVLNMPFALVT 141
TL +++ + LGNL V + ++R+ N+ + +LA +D L++ P +
Sbjct: 71 YTLGTVILLVGLTGMLGNLTVIYTFCRSRSLRTPANMFIINLAVSDFLMSFTQAPVFFTS 130
Query: 142 ILTTRWIFGKFFCRVSAMFFWLFVIEGVAILLIISIDRFLIIVQRQDKL---NPYRAKVL 198
L +W+FG+ C A LF I + L I++DR+L+I + + RA +
Sbjct: 131 SLYKQWLFGETGCEFYAFCGALFGISSMITLTAIALDRYLVITRPLATFGVASKRRAAFV 190
Query: 199 IAVSWATSFCVAFPLAVGNPDLQIPSRAPQCVFGYTT-NPGYQAYVILISLISFFIPFLV 257
+ W + + P G C + Y + P +AY +L+ FF+P L+
Sbjct: 191 LLGVWLYALAWSLPPFFGWSAYVPEGLLTSCSWDYMSFTPAVRAYTMLLCCFVFFLPLLI 250
Query: 258 ILYSFMGILNTLRHNALRIHSYPEGICLSQASKLGLMSLQRPFQMSIDMGFKTRAFTTIL 317
I+Y ++ I +R + ++ G C L QR S + + +L
Sbjct: 251 IIYCYIFIFRAIRETGRALQTF--GACKGNGESL----WQRQRLQS-----ECKMAKIML 299
Query: 318 ILFAVFIVCWAPFTTYSLVATFSKHFYYQHNFFEISTWLLWLCYLKSAL-NPLIYYWRIK 376
++ +F++ WAP++ +LVA Y H + + + SA+ NP+IY
Sbjct: 300 LVILLFVLSWAPYSAVALVAFAG----YAHVLTPYMSSVPAVIAKASAIHNPIIYAITHP 355
Query: 377 KFHDACLDMMPKSFKFLPQLPGHTKRRIRPSAVY 410
K+ A +P L L G ++R RP Y
Sbjct: 356 KYRVAIAQHLP----CLGVLLGVSRRHSRPYPSY 385
>gi|4758474 G protein-coupled receptor 10 [Homo sapiens]
Length = 370
Score = 99.8 bits (247), Expect = 4e-21
Identities = 80/332 (24%), Positives = 146/332 (43%), Gaps = 39/332 (11%)
Query: 63 STAVPTTPAA--FKSLNLPLQITLSAIMIF--ILFVSFLGNLVVCLMVYQKAAMRSAINI 118
S A PA F+SL L Q+ ++++ ++ V +GN ++ L++ + + + N
Sbjct: 38 SVAGADAPAVTPFQSLQLVHQLKGLIVLLYSVVVVVGLVGNCLLVLVIARVRRLHNVTNF 97
Query: 119 LLASLAFADMLLAVLNMPFALVTILTTR-WIFGKFFCRVSAMFFWLFVIEGVAILLIISI 177
L+ +LA +D+L+ +P L R W+FG C + + V V L I++
Sbjct: 98 LIGNLALSDVLMCTACVPLTLAYAFEPRGWVFGGGLCHLVFFLQPVTVYVSVFTLTTIAV 157
Query: 178 DRFLIIVQRQDKLNPYRAKVLIAVS-------WATSFCVAFPLAVGNPDLQI-PSRAPQC 229
DR++++V +P R ++ + +S WA S +A P AV +++ P C
Sbjct: 158 DRYVVLV------HPLRRRISLRLSAYAVLAIWALSAVLALPAAVHTYHVELKPHDVRLC 211
Query: 230 V-FGYTTNPGYQAYVILISLISFFIPFLVILYSFMGILNTLRHNALRIHSYPEGICLSQA 288
F + Q Y + L+++ +P LVIL S++ + LR+ + C++Q+
Sbjct: 212 EEFWGSQERQRQLYAWGLLLVTYLLPLLVILLSYVRVSVKLRNRVVPG-------CVTQS 264
Query: 289 SKLGLMSLQRPFQMSIDMGFKTRAFTTILILFAVFIVCWAPFTTYSLVATFSKHFYYQHN 348
Q D + R F ++++ VF VCW P ++L+ H +
Sbjct: 265 ------------QADWDRARRRRTFCLLVVVVVVFAVCWLPLHVFNLLRDLDPHAIDPYA 312
Query: 349 FFEISTWLLWLCYLKSALNPLIYYWRIKKFHD 380
F + WL + NP IY W F +
Sbjct: 313 FGLVQLLCHWLAMSSACYNPFIYAWLHDSFRE 344
>gi|4504545 5-hydroxytryptamine (serotonin) receptor 6 [Homo
sapiens]
Length = 440
Score = 97.1 bits (240), Expect = 3e-20
Identities = 78/316 (24%), Positives = 149/316 (47%), Gaps = 20/316 (6%)
Query: 84 LSAIMIFILFVSFLGNLVVCLMVYQKAAMRSAINILLASLAFADMLLAVLNMPFALVTIL 143
++A + ++ ++ N ++ ++ + A+R+ N L SL +D+++ ++ MP A++ L
Sbjct: 29 VAAALCVVIALTAAANSLLIALICTQPALRNTSNFFLVSLFTSDLMVGLVVMPPAMLNAL 88
Query: 144 TTRWIFGKFFCRVSAMFFWLFVIEGVAILLIISIDRFLII---VQRQDKLNPYRAKVLIA 200
RW+ + C + F + + L +IS+DR+L+I ++ + ++ P RA L+
Sbjct: 89 YGRWVLARGLCLLWTAFDVMCCSASILNLCLISLDRYLLILSPLRYKLRMTPLRALALVL 148
Query: 201 VSWATSFCVAF-PLAVGNPDLQIPSRAPQCVFGYTTNPGYQAYVILISLISFFIPFLVIL 259
+W+ + +F PL +G +L A V G +V++ S ++FF+P I
Sbjct: 149 GAWSLAALASFLPLLLGWHEL---GHARPPVPGQCRLLASLPFVLVASGLTFFLPSGAIC 205
Query: 260 YSFMGILNTLRHNALRIHSYPEGICLSQASKLGLMSLQRPFQMSID---MGFK-----TR 311
+++ IL R A+++ S G+ + L + RP S D + K +
Sbjct: 206 FTYCRILLAARKQAVQVASLTTGMASQASETLQVPRTPRPGVESADSRRLATKHSRKALK 265
Query: 312 AFTTILILFAVFIVCWAPFTTYSLVATFSKHFYYQHNFFEISTWLLWLCYLKSALNPLIY 371
A T+ IL +F V W PF ++V F++ L WL Y S +NP+IY
Sbjct: 266 ASLTLGILLGMFFVTWLPFFVANIVQAVCD--CISPGLFDV---LTWLGYCNSTMNPIIY 320
Query: 372 YWRIKKFHDACLDMMP 387
++ F A +P
Sbjct: 321 PLFMRDFKRALGRFLP 336
>gi|110618256 trace amine associated receptor 9 [Homo sapiens]
Length = 348
Score = 96.7 bits (239), Expect = 4e-20
Identities = 81/294 (27%), Positives = 135/294 (45%), Gaps = 23/294 (7%)
Query: 84 LSAIMIFILFVSFLGNLVVCLMVYQKAAMRSAINILLASLAFADMLLAVLNMPFALVTIL 143
L A++ F ++ GNL+V + + + + N L+ASLA AD L+ V MPF+ V +
Sbjct: 35 LYAVLGFGAVLAAFGNLLVMIAILHFKQLHTPTNFLIASLACADFLVGVTVMPFSTVRSV 94
Query: 144 TTRWIFGKFFCRVSAMFFWLFVIEGVAILLIISIDRFLII---VQRQDKLNPYRAKVLIA 200
+ W FG +C+ F F + L IS+DR++ + + K + + I
Sbjct: 95 ESCWYFGDSYCKFHTCFDTSFCFASLFHLCCISVDRYIAVTDPLTYPTKFTVSVSGICIV 154
Query: 201 VSWATSFCVAFPL---AVGNPDLQIPSRAPQCVFGYTTNPGYQAYVILISLISFFIPFLV 257
+SW S +F + ++ A CV G P Q +V+L L+ FFIP +
Sbjct: 155 LSWFFSVTYSFSIFYTGANEEGIEELVVALTCVGGCQA-PLNQNWVLLCFLL-FFIPNVA 212
Query: 258 ILYSFMGILNTLRHNALRIHSYPEGICLSQASKLGLMSLQRPFQMSIDMGFKTRAFTTIL 317
+++ + I +H A +I S SQA +R + + +A T+
Sbjct: 213 MVFIYSKIFLVAKHQARKIES-----TASQAQSSSESYKERVAKR------ERKAAKTLG 261
Query: 318 ILFAVFIVCWAPFTTYSLVATFSKHFYYQHNFFEISTWLLWLCYLKSALNPLIY 371
I A F+V W P+ +++ + +F +EI L+W Y SA+NPLIY
Sbjct: 262 IAMAAFLVSWLPYLVDAVIDAY-MNFITPPYVYEI---LVWCVYYNSAMNPLIY 311
>gi|10835175 5-hydroxytryptamine (serotonin) receptor 2A [Homo
sapiens]
Length = 471
Score = 96.3 bits (238), Expect = 5e-20
Identities = 85/335 (25%), Positives = 151/335 (45%), Gaps = 28/335 (8%)
Query: 69 TPAAFKSLNLPLQITLSAIMIFILFVSFLGNLVVCLMVYQKAAMRSAINILLASLAFADM 128
+P+ L+L + + + ++ ++ GN++V + V + +++A N L SLA ADM
Sbjct: 62 SPSCLSLLHLQEKNWSALLTAVVIILTIAGNILVIMAVSLEKKLQNATNYFLMSLAIADM 121
Query: 129 LLAVLNMPFALVTIL-TTRWIFGKFFCRVSAMFFWLFVIEGVAILLIISIDRFLII---V 184
LL L MP +++TIL RW C V LF + L IS+DR++ I +
Sbjct: 122 LLGFLVMPVSMLTILYGYRWPLPSKLCAVWIYLDVLFSTASIMHLCAISLDRYVAIQNPI 181
Query: 185 QRQDKLNPYRAKVLIAVSWATSFCVAFPLAV-GNPDLQIPSRAPQCVFGYTTNPGYQAYV 243
+ +A + I W S ++ P+ V G D + C+ +V
Sbjct: 182 HHSRFNSRTKAFLKIIAVWTISVGISMPIPVFGLQDDSKVFKEGSCLLADDN------FV 235
Query: 244 ILISLISFFIPFLVILYSFMGILNTLRHNA-LRIHSYPEGICLSQASKLGLMSL--QRPF 300
++ S +SFFIP +++ ++ + +L+ A L + L+ S L SL ++ F
Sbjct: 236 LIGSFVSFFIPLTIMVITYFLTIKSLQKEATLCVSDLGTRAKLASFSFLPQSSLSSEKLF 295
Query: 301 QMSI--------------DMGFKTRAFTTILILFAVFIVCWAPFTTYSLVATFSKHFYYQ 346
Q SI + + +A + I+F +F+V W PF +++A K +
Sbjct: 296 QRSIHREPGSYTGRRTMQSISNEQKACKVLGIVFFLFVVMWCPFFITNIMAVICKESCNE 355
Query: 347 HNFFEISTWLLWLCYLKSALNPLIYYWRIKKFHDA 381
+ +W+ YL SA+NPL+Y K + A
Sbjct: 356 DVIGALLNVFVWIGYLSSAVNPLVYTLFNKTYRSA 390
>gi|111118990 alpha-1A-adrenergic receptor isoform 4 [Homo sapiens]
Length = 455
Score = 95.9 bits (237), Expect = 6e-20
Identities = 89/369 (24%), Positives = 159/369 (43%), Gaps = 39/369 (10%)
Query: 76 LNLPLQITLSAIMIFILFVSFLGNLVVCLMVYQKAAMRSAINILLASLAFADMLLAVLNM 135
+N+ I L I+ ++ LGN++V L V + S + + +LA AD+LL +
Sbjct: 21 VNISKAILLGVILGGLILFGVLGNILVILSVACHRHLHSVTHYYIVNLAVADLLLTSTVL 80
Query: 136 PFALVTILTTRWIFGKFFCRVSAMFFWLFVIEGVAILLIISIDRFLII---VQRQDKLNP 192
PF+ + + W FG+ FC + A L + L IISIDR++ + ++ +
Sbjct: 81 PFSAIFEVLGYWAFGRVFCNIWAAVDVLCCTASIMGLCIISIDRYIGVSYPLRYPTIVTQ 140
Query: 193 YRAKVLIAVSWATSFCVAFPLAVGNPDLQIPSRAPQCVFGYTTNPGYQAYVILISLISFF 252
R + + WA S ++ G + P+ + + PG YV+ +L SF+
Sbjct: 141 RRGLMALLCVWALSLVISIGPLFG---WRQPAPEDETICQINEEPG---YVLFSALGSFY 194
Query: 253 IPFLVILYSF-----------MGILNTLRHN-------ALRIHSYPEGICLSQASKLGLM 294
+P +IL + G+ + L+ + LRIH + A G+
Sbjct: 195 LPLAIILVMYCRVYVVAKRESRGLKSGLKTDKSDSEQVTLRIHRKN-----APAGGSGMA 249
Query: 295 SLQRPFQMSIDM---GFKTRAFTTILILFAVFIVCWAPFTTYSLVATFSKHFYYQHNFFE 351
S + S+ + + +A T+ I+ F++CW PF + +F F F+
Sbjct: 250 SAKTKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPDFKPSETVFK 309
Query: 352 ISTWLLWLCYLKSALNPLIYYWRIKKFHDACLDMMPKSFKFLPQLPGHT-KRRIRPSAVY 410
I + WL YL S +NP+IY ++F A +++ Q H + P +
Sbjct: 310 I---VFWLGYLNSCINPIIYPCSSQEFKKAFQNVLRIQCLCRKQSSKHALGYTLHPPSQA 366
Query: 411 VCGEHRTVV 419
V G+H+ +V
Sbjct: 367 VEGQHKDMV 375
>gi|111118992 alpha-1A-adrenergic receptor isoform 1 [Homo sapiens]
Length = 466
Score = 95.9 bits (237), Expect = 6e-20
Identities = 89/369 (24%), Positives = 159/369 (43%), Gaps = 39/369 (10%)
Query: 76 LNLPLQITLSAIMIFILFVSFLGNLVVCLMVYQKAAMRSAINILLASLAFADMLLAVLNM 135
+N+ I L I+ ++ LGN++V L V + S + + +LA AD+LL +
Sbjct: 21 VNISKAILLGVILGGLILFGVLGNILVILSVACHRHLHSVTHYYIVNLAVADLLLTSTVL 80
Query: 136 PFALVTILTTRWIFGKFFCRVSAMFFWLFVIEGVAILLIISIDRFLII---VQRQDKLNP 192
PF+ + + W FG+ FC + A L + L IISIDR++ + ++ +
Sbjct: 81 PFSAIFEVLGYWAFGRVFCNIWAAVDVLCCTASIMGLCIISIDRYIGVSYPLRYPTIVTQ 140
Query: 193 YRAKVLIAVSWATSFCVAFPLAVGNPDLQIPSRAPQCVFGYTTNPGYQAYVILISLISFF 252
R + + WA S ++ G + P+ + + PG YV+ +L SF+
Sbjct: 141 RRGLMALLCVWALSLVISIGPLFG---WRQPAPEDETICQINEEPG---YVLFSALGSFY 194
Query: 253 IPFLVILYSF-----------MGILNTLRHN-------ALRIHSYPEGICLSQASKLGLM 294
+P +IL + G+ + L+ + LRIH + A G+
Sbjct: 195 LPLAIILVMYCRVYVVAKRESRGLKSGLKTDKSDSEQVTLRIHRKN-----APAGGSGMA 249
Query: 295 SLQRPFQMSIDM---GFKTRAFTTILILFAVFIVCWAPFTTYSLVATFSKHFYYQHNFFE 351
S + S+ + + +A T+ I+ F++CW PF + +F F F+
Sbjct: 250 SAKTKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPDFKPSETVFK 309
Query: 352 ISTWLLWLCYLKSALNPLIYYWRIKKFHDACLDMMPKSFKFLPQLPGHT-KRRIRPSAVY 410
I + WL YL S +NP+IY ++F A +++ Q H + P +
Sbjct: 310 I---VFWLGYLNSCINPIIYPCSSQEFKKAFQNVLRIQCLCRKQSSKHALGYTLHPPSQA 366
Query: 411 VCGEHRTVV 419
V G+H+ +V
Sbjct: 367 VEGQHKDMV 375
>gi|111118986 alpha-1A-adrenergic receptor isoform 2 [Homo sapiens]
Length = 475
Score = 95.9 bits (237), Expect = 6e-20
Identities = 89/369 (24%), Positives = 159/369 (43%), Gaps = 39/369 (10%)
Query: 76 LNLPLQITLSAIMIFILFVSFLGNLVVCLMVYQKAAMRSAINILLASLAFADMLLAVLNM 135
+N+ I L I+ ++ LGN++V L V + S + + +LA AD+LL +
Sbjct: 21 VNISKAILLGVILGGLILFGVLGNILVILSVACHRHLHSVTHYYIVNLAVADLLLTSTVL 80
Query: 136 PFALVTILTTRWIFGKFFCRVSAMFFWLFVIEGVAILLIISIDRFLII---VQRQDKLNP 192
PF+ + + W FG+ FC + A L + L IISIDR++ + ++ +
Sbjct: 81 PFSAIFEVLGYWAFGRVFCNIWAAVDVLCCTASIMGLCIISIDRYIGVSYPLRYPTIVTQ 140
Query: 193 YRAKVLIAVSWATSFCVAFPLAVGNPDLQIPSRAPQCVFGYTTNPGYQAYVILISLISFF 252
R + + WA S ++ G + P+ + + PG YV+ +L SF+
Sbjct: 141 RRGLMALLCVWALSLVISIGPLFG---WRQPAPEDETICQINEEPG---YVLFSALGSFY 194
Query: 253 IPFLVILYSF-----------MGILNTLRHN-------ALRIHSYPEGICLSQASKLGLM 294
+P +IL + G+ + L+ + LRIH + A G+
Sbjct: 195 LPLAIILVMYCRVYVVAKRESRGLKSGLKTDKSDSEQVTLRIHRKN-----APAGGSGMA 249
Query: 295 SLQRPFQMSIDM---GFKTRAFTTILILFAVFIVCWAPFTTYSLVATFSKHFYYQHNFFE 351
S + S+ + + +A T+ I+ F++CW PF + +F F F+
Sbjct: 250 SAKTKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPDFKPSETVFK 309
Query: 352 ISTWLLWLCYLKSALNPLIYYWRIKKFHDACLDMMPKSFKFLPQLPGHT-KRRIRPSAVY 410
I + WL YL S +NP+IY ++F A +++ Q H + P +
Sbjct: 310 I---VFWLGYLNSCINPIIYPCSSQEFKKAFQNVLRIQCLCRKQSSKHALGYTLHPPSQA 366
Query: 411 VCGEHRTVV 419
V G+H+ +V
Sbjct: 367 VEGQHKDMV 375
>gi|111118988 alpha-1A-adrenergic receptor isoform 3 [Homo sapiens]
Length = 429
Score = 95.9 bits (237), Expect = 6e-20
Identities = 89/369 (24%), Positives = 159/369 (43%), Gaps = 39/369 (10%)
Query: 76 LNLPLQITLSAIMIFILFVSFLGNLVVCLMVYQKAAMRSAINILLASLAFADMLLAVLNM 135
+N+ I L I+ ++ LGN++V L V + S + + +LA AD+LL +
Sbjct: 21 VNISKAILLGVILGGLILFGVLGNILVILSVACHRHLHSVTHYYIVNLAVADLLLTSTVL 80
Query: 136 PFALVTILTTRWIFGKFFCRVSAMFFWLFVIEGVAILLIISIDRFLII---VQRQDKLNP 192
PF+ + + W FG+ FC + A L + L IISIDR++ + ++ +
Sbjct: 81 PFSAIFEVLGYWAFGRVFCNIWAAVDVLCCTASIMGLCIISIDRYIGVSYPLRYPTIVTQ 140
Query: 193 YRAKVLIAVSWATSFCVAFPLAVGNPDLQIPSRAPQCVFGYTTNPGYQAYVILISLISFF 252
R + + WA S ++ G + P+ + + PG YV+ +L SF+
Sbjct: 141 RRGLMALLCVWALSLVISIGPLFG---WRQPAPEDETICQINEEPG---YVLFSALGSFY 194
Query: 253 IPFLVILYSF-----------MGILNTLRHN-------ALRIHSYPEGICLSQASKLGLM 294
+P +IL + G+ + L+ + LRIH + A G+
Sbjct: 195 LPLAIILVMYCRVYVVAKRESRGLKSGLKTDKSDSEQVTLRIHRKN-----APAGGSGMA 249
Query: 295 SLQRPFQMSIDM---GFKTRAFTTILILFAVFIVCWAPFTTYSLVATFSKHFYYQHNFFE 351
S + S+ + + +A T+ I+ F++CW PF + +F F F+
Sbjct: 250 SAKTKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPDFKPSETVFK 309
Query: 352 ISTWLLWLCYLKSALNPLIYYWRIKKFHDACLDMMPKSFKFLPQLPGHT-KRRIRPSAVY 410
I + WL YL S +NP+IY ++F A +++ Q H + P +
Sbjct: 310 I---VFWLGYLNSCINPIIYPCSSQEFKKAFQNVLRIQCLCRKQSSKHALGYTLHPPSQA 366
Query: 411 VCGEHRTVV 419
V G+H+ +V
Sbjct: 367 VEGQHKDMV 375
>gi|5174595 melatonin receptor 1B [Homo sapiens]
Length = 362
Score = 95.9 bits (237), Expect = 6e-20
Identities = 79/292 (27%), Positives = 121/292 (41%), Gaps = 30/292 (10%)
Query: 84 LSAIMIFILFVSFLGNLVVCLMVYQKAAMRSAINILLASLAFADMLLAVLNMPFALVTIL 143
LSA++I V +GNL+V L V + +R+A N+ L SLA AD+++A P LV I
Sbjct: 43 LSAVLIVTTAVDVVGNLLVILSVLRNRKLRNAGNLFLVSLALADLVVAFYPYPLILVAIF 102
Query: 144 TTRWIFGKFFCRVSAMFFWLFVIEGVAILLIISIDRFLIIVQRQDKLNPYR---AKVLIA 200
W G+ C+ SA L VI V + I+I+R+ I YR + I
Sbjct: 103 YDGWALGEEHCKASAFVMGLSVIGSVFNITAIAINRYCYICHSMAYHRIYRRWHTPLHIC 162
Query: 201 VSWATSFCVAFP-LAVGNPDLQIPSRAPQCVFGYTTNPGYQAYVILISLISFFIPFLVIL 259
+ W + P VG+ L+ R C F T + Y A V+ +I F +P V+
Sbjct: 163 LIWLLTVVALLPNFFVGS--LEYDPRIYSCTFIQTASTQYTAAVV---VIHFLLPIAVVS 217
Query: 260 YSFMGILNTLRHNALRIHSYPEGICLSQASKLGLMSLQRPFQMSIDMGFKTRAFTTILIL 319
+ ++ I L A R +CL + R+F T+ ++
Sbjct: 218 FCYLRIW-VLVLQARRKAKPESRLCLKPSD--------------------LRSFLTMFVV 256
Query: 320 FAVFIVCWAPFTTYSLVATFSKHFYYQHNFFEISTWLLWLCYLKSALNPLIY 371
F +F +CWAP L + + L Y S LN ++Y
Sbjct: 257 FVIFAICWAPLNCIGLAVAINPQEMAPQIPEGLFVTSYLLAYFNSCLNAIVY 308
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.332 0.142 0.446
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,739,183
Number of Sequences: 37866
Number of extensions: 607719
Number of successful extensions: 3239
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 474
Number of HSP's successfully gapped in prelim test: 180
Number of HSP's that attempted gapping in prelim test: 2021
Number of HSP's gapped (non-prelim): 895
length of query: 419
length of database: 18,247,518
effective HSP length: 105
effective length of query: 314
effective length of database: 14,271,588
effective search space: 4481278632
effective search space used: 4481278632
T: 11
A: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (22.0 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.