Search of human proteins with 212286172

Search of human proteins with 212286172

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|212286172 RNA polymerase I polypeptide B isoform 2 [Homo
sapiens]
         (1079 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|212286172 RNA polymerase I polypeptide B isoform 2 [Homo sapi...  2209   0.0  
gi|33469941 RNA polymerase I polypeptide B isoform 1 [Homo sapiens]  2123   0.0  
gi|238908505 DNA-directed RNA polymerase III B isoform 2 [Homo s...   388   e-107
gi|238908503 DNA-directed RNA polymerase III B isoform 1 [Homo s...   388   e-107
gi|4505941 DNA directed RNA polymerase II polypeptide B [Homo sa...   378   e-104
gi|61742777 leucyl/cystinyl aminopeptidase isoform 1 [Homo sapiens]    36   0.22 
gi|61742775 leucyl/cystinyl aminopeptidase isoform 2 [Homo sapiens]    36   0.22 
gi|96975023 ankyrin repeat and death domain containing 1A [Homo ...    31   7.2  

>gi|212286172 RNA polymerase I polypeptide B isoform 2 [Homo sapiens]
          Length = 1079

 Score = 2209 bits (5725), Expect = 0.0
 Identities = 1079/1079 (100%), Positives = 1079/1079 (100%)

Query: 1    MDPGSRWRNLPSGPSLKHLTDPSYGIPREQQKAALQELTRAHVESFNYAVHEGLGLAVQA 60
            MDPGSRWRNLPSGPSLKHLTDPSYGIPREQQKAALQELTRAHVESFNYAVHEGLGLAVQA
Sbjct: 1    MDPGSRWRNLPSGPSLKHLTDPSYGIPREQQKAALQELTRAHVESFNYAVHEGLGLAVQA 60

Query: 61   DINWAVNGISKGIIKQFLGYVPIMVKSKLCNLRNLPPQALIEHHEEAEEMGGYFIINGIE 120
            DINWAVNGISKGIIKQFLGYVPIMVKSKLCNLRNLPPQALIEHHEEAEEMGGYFIINGIE
Sbjct: 61   DINWAVNGISKGIIKQFLGYVPIMVKSKLCNLRNLPPQALIEHHEEAEEMGGYFIINGIE 120

Query: 121  KVIRMLIMPRRNFPIAMIRPKWKTRGPGYTQYGVSMHCVREEHSAVNMNLHYLENGTVML 180
            KVIRMLIMPRRNFPIAMIRPKWKTRGPGYTQYGVSMHCVREEHSAVNMNLHYLENGTVML
Sbjct: 121  KVIRMLIMPRRNFPIAMIRPKWKTRGPGYTQYGVSMHCVREEHSAVNMNLHYLENGTVML 180

Query: 181  NFIYRKELFFLPLGFALKALVSFSDYQIFQELIKGKEDDSFLRNSVSQMLRIVMEEGCST 240
            NFIYRKELFFLPLGFALKALVSFSDYQIFQELIKGKEDDSFLRNSVSQMLRIVMEEGCST
Sbjct: 181  NFIYRKELFFLPLGFALKALVSFSDYQIFQELIKGKEDDSFLRNSVSQMLRIVMEEGCST 240

Query: 241  QKQVLNYLGECFRVKLNVPDWYPNEQAAEFLFNQCICIHLKSNTEKFYMLCLMTRKLFAL 300
            QKQVLNYLGECFRVKLNVPDWYPNEQAAEFLFNQCICIHLKSNTEKFYMLCLMTRKLFAL
Sbjct: 241  QKQVLNYLGECFRVKLNVPDWYPNEQAAEFLFNQCICIHLKSNTEKFYMLCLMTRKLFAL 300

Query: 301  AKGECMEDNPDSLVNQEVLTPGQLFLMFLKEKLEGWLVSIKIAFDKKAQKTSVSMNTDNL 360
            AKGECMEDNPDSLVNQEVLTPGQLFLMFLKEKLEGWLVSIKIAFDKKAQKTSVSMNTDNL
Sbjct: 301  AKGECMEDNPDSLVNQEVLTPGQLFLMFLKEKLEGWLVSIKIAFDKKAQKTSVSMNTDNL 360

Query: 361  MRIFTMGIDLTKPFEYLFATGNLRSKTGLGLLQDSGLCVVADKLNFIRYLSHFRCVHRGA 420
            MRIFTMGIDLTKPFEYLFATGNLRSKTGLGLLQDSGLCVVADKLNFIRYLSHFRCVHRGA
Sbjct: 361  MRIFTMGIDLTKPFEYLFATGNLRSKTGLGLLQDSGLCVVADKLNFIRYLSHFRCVHRGA 420

Query: 421  DFAKMRTTTVRRLLPESWGFLCPVHTPDGEPCGLMNHLTAVCEVVTQFVYTASIPALLCN 480
            DFAKMRTTTVRRLLPESWGFLCPVHTPDGEPCGLMNHLTAVCEVVTQFVYTASIPALLCN
Sbjct: 421  DFAKMRTTTVRRLLPESWGFLCPVHTPDGEPCGLMNHLTAVCEVVTQFVYTASIPALLCN 480

Query: 481  LGVTPIDGAPHRSYSECYPVLLDGVMVGWVDKDLAPGIADSLRHFKVLREKRIPPWMEVV 540
            LGVTPIDGAPHRSYSECYPVLLDGVMVGWVDKDLAPGIADSLRHFKVLREKRIPPWMEVV
Sbjct: 481  LGVTPIDGAPHRSYSECYPVLLDGVMVGWVDKDLAPGIADSLRHFKVLREKRIPPWMEVV 540

Query: 541  LIPMTGKPSLYPGLFLFTTPCRLVRPVQNLALGKEELIGTMEQIFMNVAIFEDEVFAGVT 600
            LIPMTGKPSLYPGLFLFTTPCRLVRPVQNLALGKEELIGTMEQIFMNVAIFEDEVFAGVT
Sbjct: 541  LIPMTGKPSLYPGLFLFTTPCRLVRPVQNLALGKEELIGTMEQIFMNVAIFEDEVFAGVT 600

Query: 601  THQELFPHSLLSVIANFIPFSDHNQSPRNMYQCQMGKQTMGFPLLTYQDRSDNKLYRLQT 660
            THQELFPHSLLSVIANFIPFSDHNQSPRNMYQCQMGKQTMGFPLLTYQDRSDNKLYRLQT
Sbjct: 601  THQELFPHSLLSVIANFIPFSDHNQSPRNMYQCQMGKQTMGFPLLTYQDRSDNKLYRLQT 660

Query: 661  PQSPLVRPSMYDYYDMDNYPIGTNAIVAVISYTGYDMEDAMIVNKASWERGFAHGSVYKS 720
            PQSPLVRPSMYDYYDMDNYPIGTNAIVAVISYTGYDMEDAMIVNKASWERGFAHGSVYKS
Sbjct: 661  PQSPLVRPSMYDYYDMDNYPIGTNAIVAVISYTGYDMEDAMIVNKASWERGFAHGSVYKS 720

Query: 721  EFIDLSEKIKQGDSSLVFGIKPGDPRVLQKLDDDGLPFIGAKLQYGDPYYSYLNLNTGES 780
            EFIDLSEKIKQGDSSLVFGIKPGDPRVLQKLDDDGLPFIGAKLQYGDPYYSYLNLNTGES
Sbjct: 721  EFIDLSEKIKQGDSSLVFGIKPGDPRVLQKLDDDGLPFIGAKLQYGDPYYSYLNLNTGES 780

Query: 781  FVMYYKSKENCVVDNIKVCSNDTGSGKFKCVCITMRVPRNPTIGDKFASRHGQKGILSRL 840
            FVMYYKSKENCVVDNIKVCSNDTGSGKFKCVCITMRVPRNPTIGDKFASRHGQKGILSRL
Sbjct: 781  FVMYYKSKENCVVDNIKVCSNDTGSGKFKCVCITMRVPRNPTIGDKFASRHGQKGILSRL 840

Query: 841  WPAEDMPFTESGMVPDILFNPHGFPSRMTIGMLIESMAGKSAALHGLCHDATPFIFSEEN 900
            WPAEDMPFTESGMVPDILFNPHGFPSRMTIGMLIESMAGKSAALHGLCHDATPFIFSEEN
Sbjct: 841  WPAEDMPFTESGMVPDILFNPHGFPSRMTIGMLIESMAGKSAALHGLCHDATPFIFSEEN 900

Query: 901  SALEYFGEMLKAAGYNFYGTERLYSGISGLELEADIFIGVVYYQRLRHMVSDKFQVRTTG 960
            SALEYFGEMLKAAGYNFYGTERLYSGISGLELEADIFIGVVYYQRLRHMVSDKFQVRTTG
Sbjct: 901  SALEYFGEMLKAAGYNFYGTERLYSGISGLELEADIFIGVVYYQRLRHMVSDKFQVRTTG 960

Query: 961  ARDRVTNQPIGGRNVQGGIRFGEMERDALLAHGTSFLLHDRLFNCSDRSVAHVCVKCGSL 1020
            ARDRVTNQPIGGRNVQGGIRFGEMERDALLAHGTSFLLHDRLFNCSDRSVAHVCVKCGSL
Sbjct: 961  ARDRVTNQPIGGRNVQGGIRFGEMERDALLAHGTSFLLHDRLFNCSDRSVAHVCVKCGSL 1020

Query: 1021 LSPLLEKPPPSWSAMRNRKYNCTLCSRSDTIDTVSVPYVFRYFVAELAAMNIKVKLDVV 1079
            LSPLLEKPPPSWSAMRNRKYNCTLCSRSDTIDTVSVPYVFRYFVAELAAMNIKVKLDVV
Sbjct: 1021 LSPLLEKPPPSWSAMRNRKYNCTLCSRSDTIDTVSVPYVFRYFVAELAAMNIKVKLDVV 1079


>gi|33469941 RNA polymerase I polypeptide B isoform 1 [Homo sapiens]
          Length = 1135

 Score = 2123 bits (5502), Expect = 0.0
 Identities = 1054/1135 (92%), Positives = 1060/1135 (93%), Gaps = 56/1135 (4%)

Query: 1    MDPGSRWRNLPSGPSLKHLTDPSYGIP--------REQQKAALQELTRAHVESFNYAVH- 51
            MDPGSRWRNLPSGPSLKHLTDPSYGIP        +E  +A ++    A  E    AV  
Sbjct: 1    MDPGSRWRNLPSGPSLKHLTDPSYGIPREQQKAALQELTRAHVESFNYAVHEGLGLAVQA 60

Query: 52   ----------EGLGLAV-------------------------------------QADINW 64
                      E +   +                                      ADINW
Sbjct: 61   IPPFEFAFKDERISFTILDAVISPPTVPKGTICKEANVYPAECRGRRSTYRGKLTADINW 120

Query: 65   AVNGISKGIIKQFLGYVPIMVKSKLCNLRNLPPQALIEHHEEAEEMGGYFIINGIEKVIR 124
            AVNGISKGIIKQFLGYVPIMVKSKLCNLRNLPPQALIEHHEEAEEMGGYFIINGIEKVIR
Sbjct: 121  AVNGISKGIIKQFLGYVPIMVKSKLCNLRNLPPQALIEHHEEAEEMGGYFIINGIEKVIR 180

Query: 125  MLIMPRRNFPIAMIRPKWKTRGPGYTQYGVSMHCVREEHSAVNMNLHYLENGTVMLNFIY 184
            MLIMPRRNFPIAMIRPKWKTRGPGYTQYGVSMHCVREEHSAVNMNLHYLENGTVMLNFIY
Sbjct: 181  MLIMPRRNFPIAMIRPKWKTRGPGYTQYGVSMHCVREEHSAVNMNLHYLENGTVMLNFIY 240

Query: 185  RKELFFLPLGFALKALVSFSDYQIFQELIKGKEDDSFLRNSVSQMLRIVMEEGCSTQKQV 244
            RKELFFLPLGFALKALVSFSDYQIFQELIKGKEDDSFLRNSVSQMLRIVMEEGCSTQKQV
Sbjct: 241  RKELFFLPLGFALKALVSFSDYQIFQELIKGKEDDSFLRNSVSQMLRIVMEEGCSTQKQV 300

Query: 245  LNYLGECFRVKLNVPDWYPNEQAAEFLFNQCICIHLKSNTEKFYMLCLMTRKLFALAKGE 304
            LNYLGECFRVKLNVPDWYPNEQAAEFLFNQCICIHLKSNTEKFYMLCLMTRKLFALAKGE
Sbjct: 301  LNYLGECFRVKLNVPDWYPNEQAAEFLFNQCICIHLKSNTEKFYMLCLMTRKLFALAKGE 360

Query: 305  CMEDNPDSLVNQEVLTPGQLFLMFLKEKLEGWLVSIKIAFDKKAQKTSVSMNTDNLMRIF 364
            CMEDNPDSLVNQEVLTPGQLFLMFLKEKLEGWLVSIKIAFDKKAQKTSVSMNTDNLMRIF
Sbjct: 361  CMEDNPDSLVNQEVLTPGQLFLMFLKEKLEGWLVSIKIAFDKKAQKTSVSMNTDNLMRIF 420

Query: 365  TMGIDLTKPFEYLFATGNLRSKTGLGLLQDSGLCVVADKLNFIRYLSHFRCVHRGADFAK 424
            TMGIDLTKPFEYLFATGNLRSKTGLGLLQDSGLCVVADKLNFIRYLSHFRCVHRGADFAK
Sbjct: 421  TMGIDLTKPFEYLFATGNLRSKTGLGLLQDSGLCVVADKLNFIRYLSHFRCVHRGADFAK 480

Query: 425  MRTTTVRRLLPESWGFLCPVHTPDGEPCGLMNHLTAVCEVVTQFVYTASIPALLCNLGVT 484
            MRTTTVRRLLPESWGFLCPVHTPDGEPCGLMNHLTAVCEVVTQFVYTASIPALLCNLGVT
Sbjct: 481  MRTTTVRRLLPESWGFLCPVHTPDGEPCGLMNHLTAVCEVVTQFVYTASIPALLCNLGVT 540

Query: 485  PIDGAPHRSYSECYPVLLDGVMVGWVDKDLAPGIADSLRHFKVLREKRIPPWMEVVLIPM 544
            PIDGAPHRSYSECYPVLLDGVMVGWVDKDLAPGIADSLRHFKVLREKRIPPWMEVVLIPM
Sbjct: 541  PIDGAPHRSYSECYPVLLDGVMVGWVDKDLAPGIADSLRHFKVLREKRIPPWMEVVLIPM 600

Query: 545  TGKPSLYPGLFLFTTPCRLVRPVQNLALGKEELIGTMEQIFMNVAIFEDEVFAGVTTHQE 604
            TGKPSLYPGLFLFTTPCRLVRPVQNLALGKEELIGTMEQIFMNVAIFEDEVFAGVTTHQE
Sbjct: 601  TGKPSLYPGLFLFTTPCRLVRPVQNLALGKEELIGTMEQIFMNVAIFEDEVFAGVTTHQE 660

Query: 605  LFPHSLLSVIANFIPFSDHNQSPRNMYQCQMGKQTMGFPLLTYQDRSDNKLYRLQTPQSP 664
            LFPHSLLSVIANFIPFSDHNQSPRNMYQCQMGKQTMGFPLLTYQDRSDNKLYRLQTPQSP
Sbjct: 661  LFPHSLLSVIANFIPFSDHNQSPRNMYQCQMGKQTMGFPLLTYQDRSDNKLYRLQTPQSP 720

Query: 665  LVRPSMYDYYDMDNYPIGTNAIVAVISYTGYDMEDAMIVNKASWERGFAHGSVYKSEFID 724
            LVRPSMYDYYDMDNYPIGTNAIVAVISYTGYDMEDAMIVNKASWERGFAHGSVYKSEFID
Sbjct: 721  LVRPSMYDYYDMDNYPIGTNAIVAVISYTGYDMEDAMIVNKASWERGFAHGSVYKSEFID 780

Query: 725  LSEKIKQGDSSLVFGIKPGDPRVLQKLDDDGLPFIGAKLQYGDPYYSYLNLNTGESFVMY 784
            LSEKIKQGDSSLVFGIKPGDPRVLQKLDDDGLPFIGAKLQYGDPYYSYLNLNTGESFVMY
Sbjct: 781  LSEKIKQGDSSLVFGIKPGDPRVLQKLDDDGLPFIGAKLQYGDPYYSYLNLNTGESFVMY 840

Query: 785  YKSKENCVVDNIKVCSNDTGSGKFKCVCITMRVPRNPTIGDKFASRHGQKGILSRLWPAE 844
            YKSKENCVVDNIKVCSNDTGSGKFKCVCITMRVPRNPTIGDKFASRHGQKGILSRLWPAE
Sbjct: 841  YKSKENCVVDNIKVCSNDTGSGKFKCVCITMRVPRNPTIGDKFASRHGQKGILSRLWPAE 900

Query: 845  DMPFTESGMVPDILFNPHGFPSRMTIGMLIESMAGKSAALHGLCHDATPFIFSEENSALE 904
            DMPFTESGMVPDILFNPHGFPSRMTIGMLIESMAGKSAALHGLCHDATPFIFSEENSALE
Sbjct: 901  DMPFTESGMVPDILFNPHGFPSRMTIGMLIESMAGKSAALHGLCHDATPFIFSEENSALE 960

Query: 905  YFGEMLKAAGYNFYGTERLYSGISGLELEADIFIGVVYYQRLRHMVSDKFQVRTTGARDR 964
            YFGEMLKAAGYNFYGTERLYSGISGLELEADIFIGVVYYQRLRHMVSDKFQVRTTGARDR
Sbjct: 961  YFGEMLKAAGYNFYGTERLYSGISGLELEADIFIGVVYYQRLRHMVSDKFQVRTTGARDR 1020

Query: 965  VTNQPIGGRNVQGGIRFGEMERDALLAHGTSFLLHDRLFNCSDRSVAHVCVKCGSLLSPL 1024
            VTNQPIGGRNVQGGIRFGEMERDALLAHGTSFLLHDRLFNCSDRSVAHVCVKCGSLLSPL
Sbjct: 1021 VTNQPIGGRNVQGGIRFGEMERDALLAHGTSFLLHDRLFNCSDRSVAHVCVKCGSLLSPL 1080

Query: 1025 LEKPPPSWSAMRNRKYNCTLCSRSDTIDTVSVPYVFRYFVAELAAMNIKVKLDVV 1079
            LEKPPPSWSAMRNRKYNCTLCSRSDTIDTVSVPYVFRYFVAELAAMNIKVKLDVV
Sbjct: 1081 LEKPPPSWSAMRNRKYNCTLCSRSDTIDTVSVPYVFRYFVAELAAMNIKVKLDVV 1135


>gi|238908505 DNA-directed RNA polymerase III B isoform 2 [Homo
            sapiens]
          Length = 1075

 Score =  388 bits (997), Expect = e-107
 Identities = 322/1055 (30%), Positives = 480/1055 (45%), Gaps = 117/1055 (11%)

Query: 78   LGYVPIMVKSKLCNLRNLPPQALIEHHEEAEEMGGYFIINGIEKVIRMLIMPRRNFPIAM 137
            +G +PIM++S  C L    P    + +E   + GGYFI+ G+EKVI +     +N  I  
Sbjct: 75   IGRMPIMLRSSNCVLTGKTPAEFAKLNECPLDPGGYFIVKGVEKVILIQEQLSKNRIIVE 134

Query: 138  IRPKWKTRGPGYTQYGVSMHCVREE-HSAVNMNLHYLENGTVMLNFIYRKELFFLPLGFA 196
               K    G   T    S H  +   + AV     YL + T+  +         +P+   
Sbjct: 135  ADRKGAV-GASVTS---STHEKKSRTNMAVKQGRFYLRHNTLSED---------IPIVII 181

Query: 197  LKALVSFSDYQIFQELIKGKEDDSFLRNSVSQMLRIVMEEGCSTQKQVLNYLGECFRVKL 256
             KA+   SD +I Q +  G E+   +  +    L    +    TQ Q L Y+G   R + 
Sbjct: 182  FKAMGVESDQEIVQMI--GTEEH--VMAAFGPSLEECQKAQIFTQMQALKYIGNKVRRQR 237

Query: 257  ---NVPDWYPNEQAAEFLFNQCICIHLKSNTEKFYMLCLMTRKLFA---LAKGECMEDNP 310
                 P     E+A E L +  I  H+      F   C+ T  +     LA+G+   D+ 
Sbjct: 238  MWGGGPKKTKIEEARELLAST-ILTHVPVKEFNFRAKCIYTAVMVRRVILAQGDNKVDDR 296

Query: 311  DSLVNQEVLTPGQLFLMFLKEKLEGWLVSIKIAFDKKAQKT-SVSMNTDNLMRIFTMGID 369
            D   N+ +   GQL  +  ++  + +   +K   D+   K  +   +    MR       
Sbjct: 297  DYYGNKRLELAGQLLSLLFEDLFKKFNSEMKKIADQVIPKQRAAQFDVVKHMR----QDQ 352

Query: 370  LTKPFEYLFATGNLRSKTGLGLLQDSGLCVVADKLNFIRYLSHFRCVHRGADFAKMRTTT 429
            +T       +TGN   K     +   G+  V  +L++I  L     +   + F K R  +
Sbjct: 353  ITNGMVNAISTGNWSLKRFK--MDRQGVTQVLSRLSYISALGMMTRI--SSQFEKTRKVS 408

Query: 430  -VRRLLPESWGFLCPVHTPDGEPCGLMNHLTAVCEVVTQFVYTASIPALLCNLGVTPID- 487
              R L P  WG LCP  TP+GE CGL+ +L  +  + T  +    I  L  NLGV  ++ 
Sbjct: 409  GPRSLQPSQWGMLCPSDTPEGEACGLVKNLALMTHITTD-MEDGPIVKLASNLGVEDVNL 467

Query: 488  -GAPHRSYSECYPVLLDGVMVGWVDKDLAPGIADSLRHFKVLREKRIPPWMEVVLIPMTG 546
                  SY   + V L+G ++G +           +  F+++R          +   +T 
Sbjct: 468  LCGEELSYPNVFLVFLNGNILGVIRDH-----KKLVNTFRLMRRAGYINEFVSISTNLTD 522

Query: 547  KPSLYPGLFLFTTPCRLVRP---------------VQNLALGKE-----------ELIGT 580
            +      +++ +   RL RP               ++ LA G             E +  
Sbjct: 523  RC-----VYISSDGGRLCRPYIIVKKQKPAVTNKHMEELAQGYRNFEDFLHESLVEYLDV 577

Query: 581  MEQIFMNVAIFEDEVFAGVTTHQELFPHSLLSVIANFIPFSDHNQSPRNMYQCQMGKQTM 640
             E+   N+A++E  +    TTH E+ P +LL V A  IP+  HNQSPRN YQC MGKQ M
Sbjct: 578  NEENDCNIALYEHTINKD-TTHLEIEPFTLLGVCAGLIPYPHHNQSPRNTYQCAMGKQAM 636

Query: 641  GFPLLTYQDRSDNKLYRLQTPQSPLVRPSMYDYYDMDNYPIGTNAIVAVISYTGYDMEDA 700
            G      ++R D  +Y L  PQ P+V+    +  + +  P G NA VAV+SY+GYD+EDA
Sbjct: 637  GTIGYNQRNRIDTLMYLLAYPQKPMVKTKTIELIEFEKLPAGQNATVAVMSYSGYDIEDA 696

Query: 701  MIVNKASWERGFAHGSVYKSEFIDLSEKIKQGDSSLVFGIKPGDPRVL----QKLDDDGL 756
            +++NKAS +RGF    VYK+    L     Q    ++  +     R      + LD DG+
Sbjct: 697  LVLNKASLDRGFGRCLVYKNAKCTLKRYTNQTFDKVMGPMLDAATRKPIWRHEILDADGI 756

Query: 757  PFIGAKLQYGD-------PYYSYLNLNTG--------ESFVMYYKSKENCVVDNIKVCSN 801
               G K++          P  + + L           +   + YK   +  ++ + + SN
Sbjct: 757  CSPGEKVENKQVLVNKSMPTVTQIPLEGSNVPQQPQYKDVPITYKGATDSYIEKVMISSN 816

Query: 802  DTGSGKFKCVCITMRVPRNPTIGDKFASRHGQKGILSRLWPAEDMPFTESGMVPDILFNP 861
               +   K +   +R  R P IGDKF+SRHGQKG+   + P EDMPF +SG+ PDI+ NP
Sbjct: 817  AEDAFLIKML---LRQTRRPEIGDKFSSRHGQKGVCGLIVPQEDMPFCDSGICPDIIMNP 873

Query: 862  HGFPSRMTIGMLIESMAGKSAALHGLCHDATPFIFSEENSALEYFGEMLKAAGYNFYGTE 921
            HGFPSRMT+G LIE +AGK+  L G  H  T F      S ++   E L   GYN+ G +
Sbjct: 874  HGFPSRMTVGKLIELLAGKAGVLDGRFHYGTAF----GGSKVKDVCEDLVRHGYNYLGKD 929

Query: 922  RLYSGISGLELEADIFIGVVYYQRLRHMVSDKFQVRTTGARDRVTNQPIGGRNVQGGIRF 981
             + SGI+G  LEA I+ G VYYQ+L+HMV DK   R  G R  +T QP  GR+  GG+R 
Sbjct: 930  YVTSGITGEPLEAYIYFGPVYYQKLKHMVLDKMHARARGPRAVLTRQPTEGRSRDGGLRL 989

Query: 982  GEMERDALLAHGTSFLLHDRLFNCSDRSVAHVCVKCGSLLSPLLEKPPPSWSAMRNRKYN 1041
            GEMERD L+ +G S LL +RL   SD     VC +CG L           W         
Sbjct: 990  GEMERDCLIGYGASMLLLERLMISSDAFEVDVCGQCGLL-------GYSGW--------- 1033

Query: 1042 CTLCSRSDTIDTVSVPYVFRYFVAELAAMNIKVKL 1076
            C  C  S  + ++ +PY  +    EL +MNI  +L
Sbjct: 1034 CHYCKSSCHVSSLRIPYACKLLFQELQSMNIIPRL 1068


>gi|238908503 DNA-directed RNA polymerase III B isoform 1 [Homo
            sapiens]
          Length = 1133

 Score =  388 bits (997), Expect = e-107
 Identities = 322/1055 (30%), Positives = 480/1055 (45%), Gaps = 117/1055 (11%)

Query: 78   LGYVPIMVKSKLCNLRNLPPQALIEHHEEAEEMGGYFIINGIEKVIRMLIMPRRNFPIAM 137
            +G +PIM++S  C L    P    + +E   + GGYFI+ G+EKVI +     +N  I  
Sbjct: 133  IGRMPIMLRSSNCVLTGKTPAEFAKLNECPLDPGGYFIVKGVEKVILIQEQLSKNRIIVE 192

Query: 138  IRPKWKTRGPGYTQYGVSMHCVREE-HSAVNMNLHYLENGTVMLNFIYRKELFFLPLGFA 196
               K    G   T    S H  +   + AV     YL + T+  +         +P+   
Sbjct: 193  ADRKGAV-GASVTS---STHEKKSRTNMAVKQGRFYLRHNTLSED---------IPIVII 239

Query: 197  LKALVSFSDYQIFQELIKGKEDDSFLRNSVSQMLRIVMEEGCSTQKQVLNYLGECFRVKL 256
             KA+   SD +I Q +  G E+   +  +    L    +    TQ Q L Y+G   R + 
Sbjct: 240  FKAMGVESDQEIVQMI--GTEEH--VMAAFGPSLEECQKAQIFTQMQALKYIGNKVRRQR 295

Query: 257  ---NVPDWYPNEQAAEFLFNQCICIHLKSNTEKFYMLCLMTRKLFA---LAKGECMEDNP 310
                 P     E+A E L +  I  H+      F   C+ T  +     LA+G+   D+ 
Sbjct: 296  MWGGGPKKTKIEEARELLAST-ILTHVPVKEFNFRAKCIYTAVMVRRVILAQGDNKVDDR 354

Query: 311  DSLVNQEVLTPGQLFLMFLKEKLEGWLVSIKIAFDKKAQKT-SVSMNTDNLMRIFTMGID 369
            D   N+ +   GQL  +  ++  + +   +K   D+   K  +   +    MR       
Sbjct: 355  DYYGNKRLELAGQLLSLLFEDLFKKFNSEMKKIADQVIPKQRAAQFDVVKHMR----QDQ 410

Query: 370  LTKPFEYLFATGNLRSKTGLGLLQDSGLCVVADKLNFIRYLSHFRCVHRGADFAKMRTTT 429
            +T       +TGN   K     +   G+  V  +L++I  L     +   + F K R  +
Sbjct: 411  ITNGMVNAISTGNWSLKRFK--MDRQGVTQVLSRLSYISALGMMTRI--SSQFEKTRKVS 466

Query: 430  -VRRLLPESWGFLCPVHTPDGEPCGLMNHLTAVCEVVTQFVYTASIPALLCNLGVTPID- 487
              R L P  WG LCP  TP+GE CGL+ +L  +  + T  +    I  L  NLGV  ++ 
Sbjct: 467  GPRSLQPSQWGMLCPSDTPEGEACGLVKNLALMTHITTD-MEDGPIVKLASNLGVEDVNL 525

Query: 488  -GAPHRSYSECYPVLLDGVMVGWVDKDLAPGIADSLRHFKVLREKRIPPWMEVVLIPMTG 546
                  SY   + V L+G ++G +           +  F+++R          +   +T 
Sbjct: 526  LCGEELSYPNVFLVFLNGNILGVIRDH-----KKLVNTFRLMRRAGYINEFVSISTNLTD 580

Query: 547  KPSLYPGLFLFTTPCRLVRP---------------VQNLALGKE-----------ELIGT 580
            +      +++ +   RL RP               ++ LA G             E +  
Sbjct: 581  RC-----VYISSDGGRLCRPYIIVKKQKPAVTNKHMEELAQGYRNFEDFLHESLVEYLDV 635

Query: 581  MEQIFMNVAIFEDEVFAGVTTHQELFPHSLLSVIANFIPFSDHNQSPRNMYQCQMGKQTM 640
             E+   N+A++E  +    TTH E+ P +LL V A  IP+  HNQSPRN YQC MGKQ M
Sbjct: 636  NEENDCNIALYEHTINKD-TTHLEIEPFTLLGVCAGLIPYPHHNQSPRNTYQCAMGKQAM 694

Query: 641  GFPLLTYQDRSDNKLYRLQTPQSPLVRPSMYDYYDMDNYPIGTNAIVAVISYTGYDMEDA 700
            G      ++R D  +Y L  PQ P+V+    +  + +  P G NA VAV+SY+GYD+EDA
Sbjct: 695  GTIGYNQRNRIDTLMYLLAYPQKPMVKTKTIELIEFEKLPAGQNATVAVMSYSGYDIEDA 754

Query: 701  MIVNKASWERGFAHGSVYKSEFIDLSEKIKQGDSSLVFGIKPGDPRVL----QKLDDDGL 756
            +++NKAS +RGF    VYK+    L     Q    ++  +     R      + LD DG+
Sbjct: 755  LVLNKASLDRGFGRCLVYKNAKCTLKRYTNQTFDKVMGPMLDAATRKPIWRHEILDADGI 814

Query: 757  PFIGAKLQYGD-------PYYSYLNLNTG--------ESFVMYYKSKENCVVDNIKVCSN 801
               G K++          P  + + L           +   + YK   +  ++ + + SN
Sbjct: 815  CSPGEKVENKQVLVNKSMPTVTQIPLEGSNVPQQPQYKDVPITYKGATDSYIEKVMISSN 874

Query: 802  DTGSGKFKCVCITMRVPRNPTIGDKFASRHGQKGILSRLWPAEDMPFTESGMVPDILFNP 861
               +   K +   +R  R P IGDKF+SRHGQKG+   + P EDMPF +SG+ PDI+ NP
Sbjct: 875  AEDAFLIKML---LRQTRRPEIGDKFSSRHGQKGVCGLIVPQEDMPFCDSGICPDIIMNP 931

Query: 862  HGFPSRMTIGMLIESMAGKSAALHGLCHDATPFIFSEENSALEYFGEMLKAAGYNFYGTE 921
            HGFPSRMT+G LIE +AGK+  L G  H  T F      S ++   E L   GYN+ G +
Sbjct: 932  HGFPSRMTVGKLIELLAGKAGVLDGRFHYGTAF----GGSKVKDVCEDLVRHGYNYLGKD 987

Query: 922  RLYSGISGLELEADIFIGVVYYQRLRHMVSDKFQVRTTGARDRVTNQPIGGRNVQGGIRF 981
             + SGI+G  LEA I+ G VYYQ+L+HMV DK   R  G R  +T QP  GR+  GG+R 
Sbjct: 988  YVTSGITGEPLEAYIYFGPVYYQKLKHMVLDKMHARARGPRAVLTRQPTEGRSRDGGLRL 1047

Query: 982  GEMERDALLAHGTSFLLHDRLFNCSDRSVAHVCVKCGSLLSPLLEKPPPSWSAMRNRKYN 1041
            GEMERD L+ +G S LL +RL   SD     VC +CG L           W         
Sbjct: 1048 GEMERDCLIGYGASMLLLERLMISSDAFEVDVCGQCGLL-------GYSGW--------- 1091

Query: 1042 CTLCSRSDTIDTVSVPYVFRYFVAELAAMNIKVKL 1076
            C  C  S  + ++ +PY  +    EL +MNI  +L
Sbjct: 1092 CHYCKSSCHVSSLRIPYACKLLFQELQSMNIIPRL 1126


>gi|4505941 DNA directed RNA polymerase II polypeptide B [Homo
            sapiens]
          Length = 1174

 Score =  378 bits (971), Expect = e-104
 Identities = 320/1080 (29%), Positives = 481/1080 (44%), Gaps = 132/1080 (12%)

Query: 75   KQFLGYVPIMVKSKLCNLRNLPPQALIEHHEEAEEMGGYFIINGIEKVIRMLIMPRRNFP 134
            K F+G +PIM++S  C L  L  + L E +E   + GGYFIING EKV+        N  
Sbjct: 146  KTFIGKIPIMLRSTYCLLNGLTDRDLCELNECPLDPGGYFIINGSEKVLIAQEKMATNTV 205

Query: 135  IAMIRPKWKTRGPGYTQYGVSMHCVREEHSAVN-MNLHYLENG-----------TVMLNF 182
                +   K     Y   G    C+       + + +  L  G            ++   
Sbjct: 206  YVFAKKDSK-----YAYTGECRSCLENSSRPTSTIWVSMLARGGQGAKKSAIGQRIVATL 260

Query: 183  IYRKELFFLPLGFALKALVSFSDYQIFQELIKGKEDDSFLRNSVSQMLRIVMEEGCSTQK 242
             Y K+   +P+    +AL   SD  I + +I   ED   +     +M++  ++E    Q+
Sbjct: 261  PYIKQE--VPIIIVFRALGFVSDRDILEHIIYDFEDPEMM-----EMVKPSLDEAFVIQE 313

Query: 243  Q--VLNYLGECFRVKLNVPDWYPNEQAAEFLFNQC---ICIHLKSNTEKFYMLCLMTRKL 297
            Q   LN++G     K  V      + A E L  +    + +     T+K Y L  M  +L
Sbjct: 314  QNVALNFIGSR-GAKPGVTKEKRIKYAKEVLQKEMLPHVGVSDFCETKKAYFLGYMVHRL 372

Query: 298  FALAKGECMEDNPDSLVNQEVLTPGQLFLMFLKEKLEGWLVSIKIAFDKKAQK-TSVSMN 356
               A G    D+ D   N+ +   G L     +   +  L  ++I   K   +    ++ 
Sbjct: 373  LLAALGRRELDDRDHYGNKRLDLAGPLLAFLFRGMFKNLLKEVRIYAQKFIDRGKDFNLE 432

Query: 357  TDNLMRIFTMGIDLTKPFEYLFATGNLRSKTGLGLLQDSGLCVVADKLNFIRYLSHFRCV 416
                 RI + G+      +Y  ATGN   +      + +G+  V ++L F   LSH R +
Sbjct: 433  LAIKTRIISDGL------KYSLATGNWGDQKKAHQAR-AGVSQVLNRLTFASTLSHLRRL 485

Query: 417  H----RGADFAKMRTTTVRRLLPESWGFLCPVHTPDGEPCGLMNHLTAVCEVVTQFVYTA 472
            +    R    AK R     +L    WG +CP  TP+G   GL+ +L A+   ++     +
Sbjct: 486  NSPIGRDGKLAKPR-----QLHNTLWGMVCPAETPEGHAVGLVKNL-ALMAYISVGSQPS 539

Query: 473  SIPALLCNLGVTPIDGAPHRSYSECYPVLLDGVMVGWVDKDLAPGIADSLRHFKVLREKR 532
             I   L    +  ++     + ++   + ++G  VG + KD    + ++LR    LR + 
Sbjct: 540  PILEFLEEWSMENLEEISPAAIADATKIFVNGCWVG-IHKD-PEQLMNTLRK---LRRQM 594

Query: 533  IPPWMEVVLIPMTGKPSLYPGLFLFTTPCRLVRPV-----QNLALGKE------------ 575
                 EV +I    +  +     ++T   R+ RP+     Q L L K             
Sbjct: 595  DIIVSEVSMIRDIREREIR----IYTDAGRICRPLLIVEKQKLLLKKRHIDQLKEREYNN 650

Query: 576  ------------ELIGTMEQIFMNVAIFEDEV------FAGVTTHQELFPHSLLSVIANF 617
                        E I T+E+  + +A+  D++      +    TH E+ P  +L V A+ 
Sbjct: 651  YSWQDLVASGVVEYIDTLEEETVMLAMTPDDLQEKEVAYCSTYTHCEIHPSMILGVCASI 710

Query: 618  IPFSDHNQSPRNMYQCQMGKQTMGFPLLTYQDRSDNKLYRLQTPQSPLVRPSMYDYYDMD 677
            IPF DHNQSPRN YQ  MGKQ MG  +  +  R D   + L  PQ PLV     +Y    
Sbjct: 711  IPFPDHNQSPRNTYQSAMGKQAMGVYITNFHVRMDTLAHVLYYPQKPLVTTRSMEYLRFR 770

Query: 678  NYPIGTNAIVAVISYTGYDMEDAMIVNKASWERGFAHGSVYKS-------EFIDLSEKIK 730
              P G N+IVA+ SYTGY+ ED++I+N+++ +RGF     Y+S       +  D  E  +
Sbjct: 771  ELPAGINSIVAIASYTGYNQEDSVIMNRSAVDRGFFRSVFYRSYKEQESKKGFDQEEVFE 830

Query: 731  QGDSSLVFGIKPGDPRVLQKLDDDGLPFIGAKL--------------QYGDPYYSYLNLN 776
            +       G++     +  KLDDDGL   G ++              +  D   S     
Sbjct: 831  KPTRETCQGMRHA---IYDKLDDDGLIAPGVRVSGDDVIIGKTVTLPENEDELESTNRRY 887

Query: 777  TGESFVMYYKSKENCVVDNIKVCSNDTGSGKFKCVCITMRVPRNPTIGDKFASRHGQKGI 836
            T      + ++ E  +VD + V  N  G   +K   I +R  R P IGDKFASRHGQKG 
Sbjct: 888  TKRDCSTFLRTSETGIVDQVMVTLNQEG---YKFCKIRVRSVRIPQIGDKFASRHGQKGT 944

Query: 837  LSRLWPAEDMPFTESGMVPDILFNPHGFPSRMTIGMLIESMAGKSAALHGLCHDATPFIF 896
                +  EDMPFT  G+ PDI+ NPH  PSRMTIG LIE + GK +A  G   DATPF  
Sbjct: 945  CGIQYRQEDMPFTCEGITPDIIINPHAIPSRMTIGHLIECLQGKVSANKGEIGDATPF-- 1002

Query: 897  SEENSALEYFGEMLKAAGYNFYGTERLYSGISGLELEADIFIGVVYYQRLRHMVSDKFQV 956
              +   ++    +L   GY+  G E LY+G +G ++ + IFIG  YYQRL+HMV DK   
Sbjct: 1003 -NDAVNVQKISNLLSDYGYHLRGNEVLYNGFTGRKITSQIFIGPTYYQRLKHMVDDKIHS 1061

Query: 957  RTTGARDRVTNQPIGGRNVQGGIRFGEMERDALLAHGTSFLLHDRLFNCSDRSVAHVCVK 1016
            R  G    +  QP+ GR+  GG+RFGEMERD  +AHG +  L +RLF  SD    HVC  
Sbjct: 1062 RARGPIQILNRQPMEGRSRDGGLRFGEMERDCQIAHGAAQFLRERLFEASDPYQVHVCNL 1121

Query: 1017 CGSLLSPLLEKPPPSWSAMRNRKYNCTLCSRSDTIDTVSVPYVFRYFVAELAAMNIKVKL 1076
            CG +          + +  R   Y C  C     I  V +PY  +    EL +M+I  ++
Sbjct: 1122 CGIM----------AIANTRTHTYECRGCRNKTQISLVRMPYACKLLFQELMSMSIAPRM 1171


>gi|61742777 leucyl/cystinyl aminopeptidase isoform 1 [Homo sapiens]
          Length = 1025

 Score = 35.8 bits (81), Expect = 0.22
 Identities = 33/149 (22%), Positives = 61/149 (40%), Gaps = 11/149 (7%)

Query: 535 PWMEVVL----IPMTGKPSLYPGLFLFTTPCRLVRPVQNLALGKEELIGT----MEQIFM 586
           PW ++ L    +P+  + SL+P L   T    +   VQ L +    ++ +    + ++  
Sbjct: 162 PWAQIRLPTAVVPLRYELSLHPNLTSMTFRGSVTISVQALQVTWNIILHSTGHNISRVTF 221

Query: 587 NVAIFEDEVFAGVTTHQELFPHSLLSVIANFIPFSDHNQSPRNMYQCQMGKQTMGFPLLT 646
             A+   E  A +    E   H  ++++A     + HN + +  Y   +     GF   +
Sbjct: 222 MSAVSSQEKQAEIL---EYAYHGQIAIVAPEALLAGHNYTLKIEYSANISSSYYGFYGFS 278

Query: 647 YQDRSDNKLYRLQTPQSPLVRPSMYDYYD 675
           Y D S+ K Y   T   PL   S +  +D
Sbjct: 279 YTDESNEKKYFAATQFEPLAARSAFPCFD 307


>gi|61742775 leucyl/cystinyl aminopeptidase isoform 2 [Homo sapiens]
          Length = 1011

 Score = 35.8 bits (81), Expect = 0.22
 Identities = 33/149 (22%), Positives = 61/149 (40%), Gaps = 11/149 (7%)

Query: 535 PWMEVVL----IPMTGKPSLYPGLFLFTTPCRLVRPVQNLALGKEELIGT----MEQIFM 586
           PW ++ L    +P+  + SL+P L   T    +   VQ L +    ++ +    + ++  
Sbjct: 148 PWAQIRLPTAVVPLRYELSLHPNLTSMTFRGSVTISVQALQVTWNIILHSTGHNISRVTF 207

Query: 587 NVAIFEDEVFAGVTTHQELFPHSLLSVIANFIPFSDHNQSPRNMYQCQMGKQTMGFPLLT 646
             A+   E  A +    E   H  ++++A     + HN + +  Y   +     GF   +
Sbjct: 208 MSAVSSQEKQAEIL---EYAYHGQIAIVAPEALLAGHNYTLKIEYSANISSSYYGFYGFS 264

Query: 647 YQDRSDNKLYRLQTPQSPLVRPSMYDYYD 675
           Y D S+ K Y   T   PL   S +  +D
Sbjct: 265 YTDESNEKKYFAATQFEPLAARSAFPCFD 293


>gi|96975023 ankyrin repeat and death domain containing 1A [Homo
           sapiens]
          Length = 522

 Score = 30.8 bits (68), Expect = 7.2
 Identities = 22/80 (27%), Positives = 40/80 (50%), Gaps = 10/80 (12%)

Query: 687 VAVISYTGYDMEDAMI-----VNKASWERGFAHGSVYKSEFI-----DLSEKIKQGDSSL 736
           V V+++   D+ED  +     + + ++ R   HG +   +F+     D + K K+G+++L
Sbjct: 137 VPVLAFIMEDLEDVALDHVDKLGRTAFHRAAEHGQLDALDFLVGSGCDHNVKDKEGNTAL 196

Query: 737 VFGIKPGDPRVLQKLDDDGL 756
                 G   VLQ+L D GL
Sbjct: 197 HLAAGRGHMAVLQRLVDIGL 216


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.323    0.139    0.428 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 42,068,751
Number of Sequences: 37866
Number of extensions: 1934703
Number of successful extensions: 3442
Number of sequences better than 10.0: 8
Number of HSP's better than 10.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 1
Number of HSP's that attempted gapping in prelim test: 3416
Number of HSP's gapped (non-prelim): 16
length of query: 1079
length of database: 18,247,518
effective HSP length: 113
effective length of query: 966
effective length of database: 13,968,660
effective search space: 13493725560
effective search space used: 13493725560
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.