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Search of human proteins with 208022687
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|208022687 GTPase regulator associated with the focal
adhesion kinase pp125 isoform b [Homo sapiens]
(759 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|208022687 GTPase regulator associated with the focal adhesion... 1512 0.0
gi|7662208 GTPase regulator associated with the focal adhesion k... 1470 0.0
gi|50843948 Rho GTPase activating protein 10 [Homo sapiens] 860 0.0
gi|221307575 Rho-type GTPase-activating protein FLJ32810 [Homo s... 724 0.0
gi|4505507 oligophrenin 1 [Homo sapiens] 649 0.0
gi|188497642 ARHGAP15 [Homo sapiens] 129 8e-30
gi|4757980 beta chimerin isoform 2 [Homo sapiens] 128 2e-29
gi|91106928 beta chimerin isoform 1 [Homo sapiens] 128 2e-29
gi|4502813 chimerin (chimaerin) 1 isoform a [Homo sapiens] 126 7e-29
gi|209364623 chimerin (chimaerin) 1 isoform b [Homo sapiens] 126 7e-29
gi|218563749 ArfGAP with coiled-coil, ankyrin repeat and PH doma... 123 6e-28
gi|187608516 centaurin, beta 2 [Homo sapiens] 121 3e-27
gi|226693398 Rho GTPase activating protein 27 isoform b [Homo sa... 120 4e-27
gi|40548322 Rho GTPase activating protein 27 isoform a [Homo sap... 120 4e-27
gi|26986534 Rho GTPase activating protein 12 [Homo sapiens] 108 2e-23
gi|47834348 minor histocompatibility antigen HA-1 [Homo sapiens] 104 3e-22
gi|150417981 glucocorticoid receptor DNA binding factor 1 [Homo ... 104 3e-22
gi|122939147 Rho GTPase activating protein 9 isoform 1 [Homo sap... 103 6e-22
gi|122939149 Rho GTPase activating protein 9 isoform 3 [Homo sap... 103 6e-22
gi|203097003 Rho GTPase activating protein 21 [Homo sapiens] 103 8e-22
gi|186910302 Rac GTPase activating protein 1 [Homo sapiens] 102 1e-21
gi|186910300 Rac GTPase activating protein 1 [Homo sapiens] 102 1e-21
gi|21361397 Rac GTPase activating protein 1 [Homo sapiens] 102 1e-21
gi|218083800 Rho GTPase-activating protein isoform 1 [Homo sapiens] 101 2e-21
gi|29469071 Rho GTPase-activating protein isoform 2 [Homo sapiens] 101 2e-21
gi|186928844 Cdc42 GTPase-activating protein [Homo sapiens] 100 9e-21
gi|23510413 sorting nexin 26 [Homo sapiens] 97 6e-20
gi|82546845 breakpoint cluster region isoform 2 [Homo sapiens] 95 2e-19
gi|82546843 breakpoint cluster region isoform 1 [Homo sapiens] 95 2e-19
gi|151108509 Rho GTPase-activating protein RICH2 [Homo sapiens] 95 3e-19
>gi|208022687 GTPase regulator associated with the focal adhesion
kinase pp125 isoform b [Homo sapiens]
Length = 759
Score = 1512 bits (3914), Expect = 0.0
Identities = 759/759 (100%), Positives = 759/759 (100%)
Query: 1 MGLPALEFSDCCLDSPHFRETLKSHEAELDKTNKFIKELIKDGKSLISALKNLSSAKRKF 60
MGLPALEFSDCCLDSPHFRETLKSHEAELDKTNKFIKELIKDGKSLISALKNLSSAKRKF
Sbjct: 1 MGLPALEFSDCCLDSPHFRETLKSHEAELDKTNKFIKELIKDGKSLISALKNLSSAKRKF 60
Query: 61 ADSLNEFKFQCIGDAETDDEMCIARSLQEFATVLRNLEDERIRMIENASEVLITPLEKFR 120
ADSLNEFKFQCIGDAETDDEMCIARSLQEFATVLRNLEDERIRMIENASEVLITPLEKFR
Sbjct: 61 ADSLNEFKFQCIGDAETDDEMCIARSLQEFATVLRNLEDERIRMIENASEVLITPLEKFR 120
Query: 121 KEQIGAAKEAKKKYDKETEKYCGILEKHLNLSSKKKESQLQEADSQVDLVRQHFYEVSLE 180
KEQIGAAKEAKKKYDKETEKYCGILEKHLNLSSKKKESQLQEADSQVDLVRQHFYEVSLE
Sbjct: 121 KEQIGAAKEAKKKYDKETEKYCGILEKHLNLSSKKKESQLQEADSQVDLVRQHFYEVSLE 180
Query: 181 YVFKVQEVQERKMFEFVEPLLAFLQGLFTFYHHGYELAKDFGDFKTQLTISIQNTRNRFE 240
YVFKVQEVQERKMFEFVEPLLAFLQGLFTFYHHGYELAKDFGDFKTQLTISIQNTRNRFE
Sbjct: 181 YVFKVQEVQERKMFEFVEPLLAFLQGLFTFYHHGYELAKDFGDFKTQLTISIQNTRNRFE 240
Query: 241 GTRSEVESLMKKMKENPLEHKTISPYTMEGYLYVQEKRHFGTSWVKHYCTYQRDSKQITM 300
GTRSEVESLMKKMKENPLEHKTISPYTMEGYLYVQEKRHFGTSWVKHYCTYQRDSKQITM
Sbjct: 241 GTRSEVESLMKKMKENPLEHKTISPYTMEGYLYVQEKRHFGTSWVKHYCTYQRDSKQITM 300
Query: 301 VPFDQKSGGKGGEDESVILKSCTRRKTDSIEKRFCFDVEAVDRPGVITMQALSEEDRRLW 360
VPFDQKSGGKGGEDESVILKSCTRRKTDSIEKRFCFDVEAVDRPGVITMQALSEEDRRLW
Sbjct: 301 VPFDQKSGGKGGEDESVILKSCTRRKTDSIEKRFCFDVEAVDRPGVITMQALSEEDRRLW 360
Query: 361 MEAMDGREPVYNSNKDSQSEGTAQLDSIGFSIIRKCIHAVETRGINEQGLYRIVGVNSRV 420
MEAMDGREPVYNSNKDSQSEGTAQLDSIGFSIIRKCIHAVETRGINEQGLYRIVGVNSRV
Sbjct: 361 MEAMDGREPVYNSNKDSQSEGTAQLDSIGFSIIRKCIHAVETRGINEQGLYRIVGVNSRV 420
Query: 421 QKLLSVLMDPKTASETETDICAEWEIKTITSALKTYLRMLPGPLMMYQFQRSFIKAAKLE 480
QKLLSVLMDPKTASETETDICAEWEIKTITSALKTYLRMLPGPLMMYQFQRSFIKAAKLE
Sbjct: 421 QKLLSVLMDPKTASETETDICAEWEIKTITSALKTYLRMLPGPLMMYQFQRSFIKAAKLE 480
Query: 481 NQESRVSEIHSLVHRLPEKNRQMLQLLMNHLANVANNHKQNLMTVANLGVVFGPTLLRPQ 540
NQESRVSEIHSLVHRLPEKNRQMLQLLMNHLANVANNHKQNLMTVANLGVVFGPTLLRPQ
Sbjct: 481 NQESRVSEIHSLVHRLPEKNRQMLQLLMNHLANVANNHKQNLMTVANLGVVFGPTLLRPQ 540
Query: 541 EETVAAIMDIKFQNIVIEILIENHEKIFNTVPDMPLTNAQLHLSRKKSSDSKPPSCSERP 600
EETVAAIMDIKFQNIVIEILIENHEKIFNTVPDMPLTNAQLHLSRKKSSDSKPPSCSERP
Sbjct: 541 EETVAAIMDIKFQNIVIEILIENHEKIFNTVPDMPLTNAQLHLSRKKSSDSKPPSCSERP 600
Query: 601 LTLFHTVQSTEKQEQRNSIINSSLESVSSNPNSILNSSSSLQPNMNSSDPDLAVVKPTRP 660
LTLFHTVQSTEKQEQRNSIINSSLESVSSNPNSILNSSSSLQPNMNSSDPDLAVVKPTRP
Sbjct: 601 LTLFHTVQSTEKQEQRNSIINSSLESVSSNPNSILNSSSSLQPNMNSSDPDLAVVKPTRP 660
Query: 661 NSLPPNPSPTSPLSPSWPMFSAPSSPMPTSSTSSDSSPVSTPFRKAKALYACKAEHDSEL 720
NSLPPNPSPTSPLSPSWPMFSAPSSPMPTSSTSSDSSPVSTPFRKAKALYACKAEHDSEL
Sbjct: 661 NSLPPNPSPTSPLSPSWPMFSAPSSPMPTSSTSSDSSPVSTPFRKAKALYACKAEHDSEL 720
Query: 721 SFTAGTVFDNVHPSQEPGWLEGTLNGKTGLIPENYVEFL 759
SFTAGTVFDNVHPSQEPGWLEGTLNGKTGLIPENYVEFL
Sbjct: 721 SFTAGTVFDNVHPSQEPGWLEGTLNGKTGLIPENYVEFL 759
>gi|7662208 GTPase regulator associated with the focal adhesion
kinase pp125 isoform a [Homo sapiens]
Length = 814
Score = 1470 bits (3805), Expect = 0.0
Identities = 754/814 (92%), Positives = 754/814 (92%), Gaps = 55/814 (6%)
Query: 1 MGLPALEFSDCCLDSPHFRETLKSHEAELDKTNKFIKELIKDGKSLISALKNLSSAKRKF 60
MGLPALEFSDCCLDSPHFRETLKSHEAELDKTNKFIKELIKDGKSLISALKNLSSAKRKF
Sbjct: 1 MGLPALEFSDCCLDSPHFRETLKSHEAELDKTNKFIKELIKDGKSLISALKNLSSAKRKF 60
Query: 61 ADSLNEFKFQCIGDAETDDEMCIARSLQEFATVLRNLEDERIRMIENASEVLITPLEKFR 120
ADSLNEFKFQCIGDAETDDEMCIARSLQEFATVLRNLEDERIRMIENASEVLITPLEKFR
Sbjct: 61 ADSLNEFKFQCIGDAETDDEMCIARSLQEFATVLRNLEDERIRMIENASEVLITPLEKFR 120
Query: 121 KEQIGAAKEAKKKYDKETEKYCGILEKHLNLSSKKKESQLQEADSQVDLVRQHFYEVSLE 180
KEQIGAAKEAKKKYDKETEKYCGILEKHLNLSSKKKESQLQEADSQVDLVRQHFYEVSLE
Sbjct: 121 KEQIGAAKEAKKKYDKETEKYCGILEKHLNLSSKKKESQLQEADSQVDLVRQHFYEVSLE 180
Query: 181 YVFKVQEVQERKMFEFVEPLLAFLQGLFTFYHHGYELAKDFGDFKTQLTISIQNTRNRFE 240
YVFKVQEVQERKMFEFVEPLLAFLQGLFTFYHHGYELAKDFGDFKTQLTISIQNTRNRFE
Sbjct: 181 YVFKVQEVQERKMFEFVEPLLAFLQGLFTFYHHGYELAKDFGDFKTQLTISIQNTRNRFE 240
Query: 241 GTRSEVESLMKKMKENPLEHKTISPYTMEGYLYVQEKRHFGTSWVKHYCTYQRDSKQITM 300
GTRSEVESLMKKMKENPLEHKTISPYTMEGYLYVQEKRHFGTSWVKHYCTYQRDSKQITM
Sbjct: 241 GTRSEVESLMKKMKENPLEHKTISPYTMEGYLYVQEKRHFGTSWVKHYCTYQRDSKQITM 300
Query: 301 VPFDQKSGGKGGEDESVILKSCTRRKTDSIEKRFCFDVEAVDRPGVITMQALSEEDRRLW 360
VPFDQKSGGKGGEDESVILKSCTRRKTDSIEKRFCFDVEAVDRPGVITMQALSEEDRRLW
Sbjct: 301 VPFDQKSGGKGGEDESVILKSCTRRKTDSIEKRFCFDVEAVDRPGVITMQALSEEDRRLW 360
Query: 361 MEAMDGREPVYNSNKDSQSEGTAQLDSIGFSIIRKCIHAVETRGINEQGLYRIVGVNSRV 420
MEAMDGREPVYNSNKDSQSEGTAQLDSIGFSIIRKCIHAVETRGINEQGLYRIVGVNSRV
Sbjct: 361 MEAMDGREPVYNSNKDSQSEGTAQLDSIGFSIIRKCIHAVETRGINEQGLYRIVGVNSRV 420
Query: 421 QKLLSVLMDPKTASETETDICAEWEIKTITSALKTYLRMLPGPLMMYQFQRSFIKAAKLE 480
QKLLSVLMDPKTASETETDICAEWEIKTITSALKTYLRMLPGPLMMYQFQRSFIKAAKLE
Sbjct: 421 QKLLSVLMDPKTASETETDICAEWEIKTITSALKTYLRMLPGPLMMYQFQRSFIKAAKLE 480
Query: 481 NQESRVSEIHSLVHRLPEKNRQMLQLLMNHLANVANNHKQNLMTVANLGVVFGPTLLRPQ 540
NQESRVSEIHSLVHRLPEKNRQMLQLLMNHLANVANNHKQNLMTVANLGVVFGPTLLRPQ
Sbjct: 481 NQESRVSEIHSLVHRLPEKNRQMLQLLMNHLANVANNHKQNLMTVANLGVVFGPTLLRPQ 540
Query: 541 EETVAAIMDIKFQNIVIEILIENHEKIFNTVPDMPLTNAQLHLSRKKSSDSKPPSCSERP 600
EETVAAIMDIKFQNIVIEILIENHEKIFNTVPDMPLTNAQLHLSRKKSSDSKPPSCSERP
Sbjct: 541 EETVAAIMDIKFQNIVIEILIENHEKIFNTVPDMPLTNAQLHLSRKKSSDSKPPSCSERP 600
Query: 601 LTLFHTVQSTEKQEQRNSIINSSLESVSSNPNSILNSSSSLQPNMNSSDPDLAVVKPTRP 660
LTLFHTVQSTEKQEQRNSIINSSLESVSSNPNSILNSSSSLQPNMNSSDPDLAVVKPTRP
Sbjct: 601 LTLFHTVQSTEKQEQRNSIINSSLESVSSNPNSILNSSSSLQPNMNSSDPDLAVVKPTRP 660
Query: 661 NSLPPNPSPTSPLSPSWPMFSAPSSPMPT---SSTSSDSSPV------------------ 699
NSLPPNPSPTSPLSPSWPMFSAPSSPMPT SS SS V
Sbjct: 661 NSLPPNPSPTSPLSPSWPMFSAPSSPMPTSSTSSDSSPVRSVAGFVWFSVAAVVLSLARS 720
Query: 700 ----------------------------------STPFRKAKALYACKAEHDSELSFTAG 725
STPFRKAKALYACKAEHDSELSFTAG
Sbjct: 721 SLHAVFSLLVNFVPCHPNLHLLFDRPEEAVHEDSSTPFRKAKALYACKAEHDSELSFTAG 780
Query: 726 TVFDNVHPSQEPGWLEGTLNGKTGLIPENYVEFL 759
TVFDNVHPSQEPGWLEGTLNGKTGLIPENYVEFL
Sbjct: 781 TVFDNVHPSQEPGWLEGTLNGKTGLIPENYVEFL 814
>gi|50843948 Rho GTPase activating protein 10 [Homo sapiens]
Length = 786
Score = 860 bits (2223), Expect = 0.0
Identities = 457/790 (57%), Positives = 574/790 (72%), Gaps = 35/790 (4%)
Query: 1 MGLPALEFSDCCLDSPHFRETLKSHEAELDKTNKFIKELIKDGKSLISALKNLSSAKRKF 60
MGL LEFSDC LDSP FRE +++HEAEL++TNKFIKELIKDGK+LI+A K+LS A+RKF
Sbjct: 1 MGLQPLEFSDCYLDSPWFRERIRAHEAELERTNKFIKELIKDGKNLIAATKSLSVAQRKF 60
Query: 61 ADSLNEFKFQCIGDAETDDEMCIARSLQEFATVLRNLEDERIRMIENASEVLITPLEKFR 120
A SL +FKF+ IGDA TDDE CI SL+EF+ L+NLE++R M + +E LI PLEKFR
Sbjct: 61 AHSLRDFKFEFIGDAVTDDERCIDASLREFSNFLKNLEEQREIMALSVTETLIKPLEKFR 120
Query: 121 KEQIGAAKEAKKKYDKETEKYCGILEKHLNLSSKKKESQLQEADSQVDLVRQHFYEVSLE 180
KEQ+GA KE KKK+DKETEK +++KHLNLS+KKK+S LQEAD QV+ RQHFYE+SLE
Sbjct: 121 KEQLGAVKEEKKKFDKETEKNYSLIDKHLNLSAKKKDSHLQEADIQVEQNRQHFYELSLE 180
Query: 181 YVFKVQEVQERKMFEFVEPLLAFLQGLFTFYHHGYELAKDFGDFKTQLTISIQNTRNRFE 240
YV K+QE+QERK FEFVEP+L+F QG+FTFYH G+ELAKDF +K +L I+IQNTRNRFE
Sbjct: 181 YVCKLQEIQERKKFEFVEPMLSFFQGMFTFYHQGHELAKDFNHYKMELQINIQNTRNRFE 240
Query: 241 GTRSEVESLMKKMKENPLEHKTISPYTMEGYLYVQEKR--HFGTSWVKHYCTYQRDSKQI 298
GTRSEVE LM K+++NP +HK S +T EGYLYVQEKR FG+SWVKHYC Y++ +K+
Sbjct: 241 GTRSEVEELMNKIRQNPKDHKRASQFTAEGYLYVQEKRPAPFGSSWVKHYCMYRKAAKKF 300
Query: 299 TMVPFDQKSGGKGGEDESVILKSCTRRKTDSIEKRFCFDVEAVDRPGV-ITMQALSEEDR 357
M+PF+ +SGGK G+ E LK CT+R TDSI++RFCFD+EA DRPGV +TMQA SEE+R
Sbjct: 301 NMIPFEHRSGGKLGDGEVFFLKECTKRHTDSIDRRFCFDIEAADRPGVSLTMQAFSEEER 360
Query: 358 RLWMEAMDGREPV---YNSNKDSQSEGTAQLDSIGFSIIRKCIHAVETRGINEQGLYRIV 414
+ W+EA+ G+E + +N+ + EG AQLD +GF+IIRKCI AVETRGIN+QGLYR+V
Sbjct: 361 KQWLEALGGKEALSHSFNTAIIPRPEGNAQLDKMGFTIIRKCISAVETRGINDQGLYRVV 420
Query: 415 GVNSRVQKLLSVLMDPKTASETETDICAEWEIKTITSALKTYLRMLPGPLMMYQFQRSFI 474
GV+S+VQ+LLS+LMD KT +E + + A+WE+KTITSALK YLR LP PLM Y+ FI
Sbjct: 421 GVSSKVQRLLSMLMDVKTCNEVDLENSADWEVKTITSALKQYLRSLPEPLMTYELHGDFI 480
Query: 475 KAAKLENQESRVSEIHSLVHRLPEKNRQMLQLLMNHLANVANNHKQNLMTVANLGVVFGP 534
AK + ESRV+ IH LVH+LPEKN++ML +L+ HL NV+N+ KQNLMTVANLGVVFGP
Sbjct: 481 VPAKSGSPESRVNAIHFLVHKLPEKNKEMLDILVKHLTNVSNHSKQNLMTVANLGVVFGP 540
Query: 535 TLLRPQEETVAAIMDIKFQNIVIEILIENHEKIFNTVPDMPLTNAQLHLSRKKSSDSKPP 594
TL+RPQEETVAA+MD+KFQNIV+EILIENHEKIF T PD T S + PP
Sbjct: 541 TLMRPQEETVAALMDLKFQNIVVEILIENHEKIFRTPPD---TTFPEPTCLSASPPNAPP 597
Query: 595 SCS-------ERPLTLFHTVQSTEKQE----QRNSIINSSLESVSSNPNSILNSSSSLQP 643
S +RP+ +++ E + + SSL+S+SS P
Sbjct: 598 RQSKRQGQRTKRPVAVYNLCLELEDGDNPYPSKEDTPTSSLDSLSSPSPVTTAVPGPPGP 657
Query: 644 NMN------SSDPDLAVVKPTRPNSL------PPNPSPTSPLSPSWPMFSAPSSPMPTS- 690
+ N S D A P + S P +P+ TS S P+ S SSP P S
Sbjct: 658 DKNHLLADGGSFGDWASTIPGQTRSSMVQWLNPQSPTTTSSNSAVTPL-SPGSSPFPFSP 716
Query: 691 -STSSDSSPVSTPFRKAKALYACKAEHDSELSFTAGTVFDNVHPSQEPGWLEGTLNGKTG 749
+T +D P S RKA+A+Y C+AEH SELSF G +F++V S+EPGWLEGTLNGK G
Sbjct: 717 PATVADKPPESIRSRKARAVYPCEAEHSSELSFEIGAIFEDVQTSREPGWLEGTLNGKRG 776
Query: 750 LIPENYVEFL 759
LIP+NYV+ L
Sbjct: 777 LIPQNYVKLL 786
>gi|221307575 Rho-type GTPase-activating protein FLJ32810 [Homo
sapiens]
Length = 874
Score = 724 bits (1868), Expect = 0.0
Identities = 390/722 (54%), Positives = 499/722 (69%), Gaps = 16/722 (2%)
Query: 1 MGLPALEFSDCCLDSPHFRETLKSHEAELDKTNKFIKELIKDGKSLISALKNLSSAKRKF 60
MGLP LEFSD LDSP FRE L+ HE EL++TNKFIKELIKDG LI AL+NLS A +KF
Sbjct: 1 MGLPTLEFSDSYLDSPDFRERLQCHEIELERTNKFIKELIKDGSLLIGALRNLSMAVQKF 60
Query: 61 ADSLNEFKFQCIGDAETDDEMCIARSLQEFATVLRNLEDERIRMIENASEVLITPLEKFR 120
+ SL +F+F+CIGDAETDDE+ IA+SL+EFA +L +E+ER R+I+NA++VLI PLEKFR
Sbjct: 61 SQSLQDFQFECIGDAETDDEISIAQSLKEFARLLIAVEEERRRLIQNANDVLIAPLEKFR 120
Query: 121 KEQIGAAKEAKKKYDKETEKYCGILEKHLNLSSKKKESQLQEADSQVDLVRQHFYEVSLE 180
KEQIGAAK+ KKK+DKE+EKY ILEKHLNLS+KKKES LQEAD+Q+D Q+FYE SLE
Sbjct: 121 KEQIGAAKDGKKKFDKESEKYYSILEKHLNLSAKKKESHLQEADTQIDREHQNFYEASLE 180
Query: 181 YVFKVQEVQERKMFEFVEPLLAFLQGLFTFYHHGYELAKDFGDFKTQLTISIQNTRNRFE 240
YVFK+QEVQE+K FEFVEPLL+FLQGLFTFYH GYELA++F +K QL ++QNTRN FE
Sbjct: 181 YVFKIQEVQEKKKFEFVEPLLSFLQGLFTFYHEGYELAQEFAPYKQQLQFNLQNTRNNFE 240
Query: 241 GTRSEVESLMKKMKENPLEHKTISPYTMEGYLYVQEKRHFGTSWVKHYCTYQRDSKQITM 300
TR EVE LM++MK +++ S +TMEGYLYVQEKR G +W+KHYCTY + SK TM
Sbjct: 241 STRQEVERLMQRMKSANQDYRPPSQWTMEGYLYVQEKRPLGFTWIKHYCTYDKGSKTFTM 300
Query: 301 VPFDQKSGGK-----GGEDESVILKSCTRRKTDSIEKRFCFDVEAVDRPGVITMQALSEE 355
+ KS GK E LKSC RRKTDSI+KRFCFD+E V+R G+IT+QA SE
Sbjct: 301 SVSEMKSSGKMNGLVTSSPEMFKLKSCIRRKTDSIDKRFCFDIEVVERHGIITLQAFSEA 360
Query: 356 DRRLWMEAMDGREPVYNSNKDSQSEGTAQLDSIGFSIIRKCIHAVETRGINEQGLYRIVG 415
+R+LW+EAMDG+EP+Y + L+ GF+ +RKCI AVETRGI GLYRI G
Sbjct: 361 NRKLWLEAMDGKEPIYTLPAIISKKEEMYLNEAGFNFVRKCIQAVETRGITILGLYRIGG 420
Query: 416 VNSRVQKLLSVLMDPKTASETETDICAEWEIKTITSALKTYLRMLPGPLMMYQFQRSFIK 475
VNS+VQKL++ PK+ + + DI W+ KTITS LK YLR L PLM Y+ + FI
Sbjct: 421 VNSKVQKLMNTTFSPKSPPDIDIDI-ELWDNKTITSGLKNYLRCLAEPLMTYKLHKDFII 479
Query: 476 AAKLENQESRVSEIHSLVHRLPEKNRQMLQLLMNHLANVANNHKQNLMTVANLGVVFGPT 535
A K ++Q RV +H+LVH+LPEKNR+ML +L+ HL V+ + +QNLMTV+NLGV+FGPT
Sbjct: 480 AVKSDDQNYRVEAVHALVHKLPEKNREMLDILIKHLVKVSLHSQQNLMTVSNLGVIFGPT 539
Query: 536 LLRPQEETVAAIMDIKFQNIVIEILIENHEKIFNTVPD--MPLTNAQLHLSRKKSSDSKP 593
L+R QEETVAA+M+IKFQNIV+EILIE++EKIF+T PD +PL Q +++
Sbjct: 540 LMRAQEETVAAMMNIKFQNIVVEILIEHYEKIFHTAPDPSIPLPQPQSRSGSRRTRAICL 599
Query: 594 PSCSERPLTLFHTVQSTEKQEQRNSIINS----SLESVSSNPN--SILNSSSSLQPNMNS 647
+ S +P + + + +S +S S+ES+SS+ + + S+S QP S
Sbjct: 600 STGSRKPRGRYTPCLAEPDSDSYSSSPDSTPMGSIESLSSHSSEQNSTTKSASCQPREKS 659
Query: 648 SDPDLAVVKPTRPNSLPPNPSPTSPLSPSWPMFSAPSSPMPTSSTSSDSSP--VSTPFRK 705
+ TSP S S + + S +S +SP VS P
Sbjct: 660 GGIPWIATPSSSNGQKSLGLWTTSPESSSREDATKTDAESDCQSVASVTSPGDVSPPIDL 719
Query: 706 AK 707
K
Sbjct: 720 VK 721
Score = 92.8 bits (229), Expect = 1e-18
Identities = 60/144 (41%), Positives = 77/144 (53%), Gaps = 17/144 (11%)
Query: 622 SSLESVSSNPNSI--LNSSSSLQPNMNSSDPDLA--VVKPTRPNSLPPN--PSPTSPLSP 675
S+ E S SI L S S + S +PDL + + R ++ N P S ++
Sbjct: 742 SAAEGNKSYSGSIQSLTSVGSKETPKASPNPDLPPKMCRRLRLDTASSNGYQRPGSVVAA 801
Query: 676 SWPMFSAPSSPMPTSSTSSDSSPVSTPFRKAKALYACKAEHDSELSFTAGTVFDNVHPSQ 735
+F SP P SS R+AKA+Y+CKAEH ELSF G +F NV+PS
Sbjct: 802 KAQLFENVGSPKPVSSG-----------RQAKAMYSCKAEHSHELSFPQGAIFSNVYPSV 850
Query: 736 EPGWLEGTLNGKTGLIPENYVEFL 759
EPGWL+ T GKTGL+PENYV FL
Sbjct: 851 EPGWLKATYEGKTGLVPENYVVFL 874
>gi|4505507 oligophrenin 1 [Homo sapiens]
Length = 802
Score = 649 bits (1674), Expect = 0.0
Identities = 354/714 (49%), Positives = 472/714 (66%), Gaps = 24/714 (3%)
Query: 1 MGLPALEFSDCCLDSPHFRETLKSHEAELDKTNKFIKELIKDGKSLISALKNLSSAKRKF 60
MG P LEFSDC LDSP FRE LK +E EL++TNKFIK++IKDG +LISA++N SSA +KF
Sbjct: 1 MGHPPLEFSDCYLDSPDFRERLKCYEQELERTNKFIKDVIKDGNALISAMRNYSSAVQKF 60
Query: 61 ADSLNEFKFQCIGDAETDDEMCIARSLQEFATVLRNLEDERIRMIENASEVLITPLEKFR 120
+ +L F+F IGD TDDE+ IA S +EFA +L +E+ER+ M+ NAS++LI PLE FR
Sbjct: 61 SQTLQSFQFDFIGDTLTDDEINIAESFKEFAELLNEVENERMMMVHNASDLLIKPLENFR 120
Query: 121 KEQIGAAKEAKKKYDKETEKYCGILEKHLNLSSKKKESQLQEADSQVDLVRQHFYEVSLE 180
KEQIG KE KKK++K+ E++ +L++HL+LSSKKKESQLQEAD QVD R +F+E SL+
Sbjct: 121 KEQIGFTKERKKKFEKDGERFYSLLDRHLHLSSKKKESQLQEADLQVDKERHNFFESSLD 180
Query: 181 YVFKVQEVQERKMFEFVEPLLAFLQGLFTFYHHGYELAKDFGDFKTQLTISIQNTRNRFE 240
YV+++QEVQE K F VEP+LAFL LF EL +DF +K QL +S+QNTRN F
Sbjct: 181 YVYQIQEVQESKKFNIVEPVLAFLHSLFISNSLTVELTQDFLPYKQQLQLSLQNTRNHFS 240
Query: 241 GTRSEVESLMKKMKENPLEHKTISPYTMEGYLYVQEKRHFGTSWVKHYCTYQRDSKQITM 300
TR E+E L K+MKE P K T+EGYLY QEK G SWVK+YC Y++++K +TM
Sbjct: 241 STREEMEELKKRMKEAPQTCKLPGQPTIEGYLYTQEKWALGISWVKYYCQYEKETKTLTM 300
Query: 301 VPFDQKSGGKGGEDESVILKSCTRRKTDSIEKRFCFDVEAVDRPGVITMQALSEEDRRLW 360
P +QK G K G + + LK C RRKT+SI+KRFCFD+E +RPG IT+QALSE +RRLW
Sbjct: 301 TPMEQKPGAKQGPLD-LTLKYCVRRKTESIDKRFCFDIETNERPGTITLQALSEANRRLW 359
Query: 361 MEAMDGREPVYNSNKDSQSEGTAQLDSIGFSIIRKCIHAVETRGINEQGLYRIVGVNSRV 420
MEAMDG+EP+Y+S Q E +L+ +GF +RKCI+ +ET+GI +GLYR VG N +V
Sbjct: 360 MEAMDGKEPIYHSPITKQQE--MELNEVGFKFVRKCINIIETKGIKTEGLYRTVGSNIQV 417
Query: 421 QKLLSVLMDPKTASETETDICAEWEIKTITSALKTYLRMLPGPLMMYQFQRSFIKAAKLE 480
QKLL+ DPK + + ++W+IKTITS+LK YLR L P+M Y+ + + AAK +
Sbjct: 418 QKLLNAFFDPKCPGDVDFH-NSDWDIKTITSSLKFYLRNLSEPVMTYRLHKELVSAAKSD 476
Query: 481 NQESRVSEIHSLVHRLPEKNRQMLQLLMNHLANVANNHKQNLMTVANLGVVFGPTLLRPQ 540
N + R+ IHSLV++LPEKNR+ML+LL+ HL NV + K+NLMT +N+GV+FGPTL+R Q
Sbjct: 477 NLDYRLGAIHSLVYKLPEKNREMLELLIRHLVNVCEHSKENLMTPSNMGVIFGPTLMRAQ 536
Query: 541 EETVAAIMDIKFQNIVIEILIENHEKIFNTVPDMPLTNAQLHLSRKKSSDSKPPSCSERP 600
E+TVAA+M+IKFQNIV+EILIE+ KI+ P+ + R + KP + S+R
Sbjct: 537 EDTVAAMMNIKFQNIVVEILIEHFGKIYLGPPEESAA-PPVPPPRVTARRHKPITISKRL 595
Query: 601 L---TLFHTVQSTEKQEQ-----RNSIINSSLESVSSNPNSILNSSSSLQPNMNSSDPDL 652
L T+F+T E +++ N I SS+E + L P S + D
Sbjct: 596 LRERTVFYTSSLDESEDEIQHQTPNGTITSSIEPPKPPQHPKL-------PIQRSGETDP 648
Query: 653 AVVKPTRP---NSLPPNPS-PTSPLSPSWPMFSAPSSPMPTSSTSSDSSPVSTP 702
P+RP L P P L +P T+ S P TP
Sbjct: 649 GRKSPSRPILDGKLEPCPEVDVGKLVSRLQDGGTKITPKATNGPMPGSGPTKTP 702
>gi|188497642 ARHGAP15 [Homo sapiens]
Length = 475
Score = 129 bits (325), Expect = 8e-30
Identities = 64/182 (35%), Positives = 108/182 (59%), Gaps = 5/182 (2%)
Query: 393 IRKCIHAVETRGINEQGLYRIVGVNSRVQKLLSVLMDPKTASETETDICAEWE-IKTITS 451
+++CI AVE RG++ G+YR+ G + +QKL ++ + + ++ +WE I +T
Sbjct: 298 VKQCIEAVEKRGLDVDGIYRVSGNLATIQKLRFIVNQEEKLNLDDS----QWEDIHVVTG 353
Query: 452 ALKTYLRMLPGPLMMYQFQRSFIKAAKLENQESRVSEIHSLVHRLPEKNRQMLQLLMNHL 511
ALK + R LP PL Y F F++A K ++ +R+ + SLV +LP NR +++L HL
Sbjct: 354 ALKMFFRELPEPLFPYSFFEQFVEAIKKQDNNTRIEAVKSLVQKLPPPNRDTMKVLFGHL 413
Query: 512 ANVANNHKQNLMTVANLGVVFGPTLLRPQEETVAAIMDIKFQNIVIEILIENHEKIFNTV 571
+ +NLM+ +LG+VFGPTLLR + ET + + +QN + E+++ + KIF +
Sbjct: 414 TKIVAKASKNLMSTQSLGIVFGPTLLRAENETGNMAIHMVYQNQIAELMLSEYSKIFGSE 473
Query: 572 PD 573
D
Sbjct: 474 ED 475
>gi|4757980 beta chimerin isoform 2 [Homo sapiens]
Length = 468
Score = 128 bits (321), Expect = 2e-29
Identities = 69/183 (37%), Positives = 105/183 (57%), Gaps = 13/183 (7%)
Query: 392 IIRKCIHAVETRGINEQGLYRIVGVNSRVQKLLSVLMDPKTASETE---TDICAEW--EI 446
++ CI +E RG+ +GLYR+ G ++ D K A + + DI A +I
Sbjct: 293 VVDICIREIEARGLKSEGLYRVSGFTEHIE-------DVKMAFDRDGEKADISANVYPDI 345
Query: 447 KTITSALKTYLRMLPGPLMMYQFQRSFIKAAKLENQESRVSEIHSLVHRLPEKNRQMLQL 506
IT ALK Y R LP P++ Y FI AAK+ N + R+ +H ++ LP + + L+
Sbjct: 346 NIITGALKLYFRDLPIPVITYDTYSKFIDAAKISNADERLEAVHEVLMLLPPAHYETLRY 405
Query: 507 LMNHLANVANNHKQNLMTVANLGVVFGPTLLRPQEE-TVAAIMDIKFQNIVIEILIENHE 565
LM HL V N K N M NLG+VFGPTL+RP E+ T+ + D+++Q ++++ILIEN +
Sbjct: 406 LMIHLKKVTMNEKDNFMNAENLGIVFGPTLMRPPEDSTLTTLHDMRYQKLIVQILIENED 465
Query: 566 KIF 568
+F
Sbjct: 466 VLF 468
>gi|91106928 beta chimerin isoform 1 [Homo sapiens]
Length = 332
Score = 128 bits (321), Expect = 2e-29
Identities = 69/183 (37%), Positives = 105/183 (57%), Gaps = 13/183 (7%)
Query: 392 IIRKCIHAVETRGINEQGLYRIVGVNSRVQKLLSVLMDPKTASETE---TDICAEW--EI 446
++ CI +E RG+ +GLYR+ G ++ D K A + + DI A +I
Sbjct: 157 VVDICIREIEARGLKSEGLYRVSGFTEHIE-------DVKMAFDRDGEKADISANVYPDI 209
Query: 447 KTITSALKTYLRMLPGPLMMYQFQRSFIKAAKLENQESRVSEIHSLVHRLPEKNRQMLQL 506
IT ALK Y R LP P++ Y FI AAK+ N + R+ +H ++ LP + + L+
Sbjct: 210 NIITGALKLYFRDLPIPVITYDTYSKFIDAAKISNADERLEAVHEVLMLLPPAHYETLRY 269
Query: 507 LMNHLANVANNHKQNLMTVANLGVVFGPTLLRPQEE-TVAAIMDIKFQNIVIEILIENHE 565
LM HL V N K N M NLG+VFGPTL+RP E+ T+ + D+++Q ++++ILIEN +
Sbjct: 270 LMIHLKKVTMNEKDNFMNAENLGIVFGPTLMRPPEDSTLTTLHDMRYQKLIVQILIENED 329
Query: 566 KIF 568
+F
Sbjct: 330 VLF 332
>gi|4502813 chimerin (chimaerin) 1 isoform a [Homo sapiens]
Length = 459
Score = 126 bits (317), Expect = 7e-29
Identities = 63/178 (35%), Positives = 108/178 (60%), Gaps = 3/178 (1%)
Query: 392 IIRKCIHAVETRGINEQGLYRIVGVNSRVQKLLSVLMDPKTASETETDICAEWEIKTITS 451
++ CI +E+RG+N +GLYR+ G + ++ + + + + + +I IT
Sbjct: 284 VVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAF--DRDGEKADISVNMYEDINIITG 341
Query: 452 ALKTYLRMLPGPLMMYQFQRSFIKAAKLENQESRVSEIHSLVHRLPEKNRQMLQLLMNHL 511
ALK Y R LP PL+ Y FI++AK+ + + ++ +H + LP + + L+ LM HL
Sbjct: 342 ALKLYFRDLPIPLITYDAYPKFIESAKIMDPDEQLETLHEALKLLPPAHCETLRYLMAHL 401
Query: 512 ANVANNHKQNLMTVANLGVVFGPTLLR-PQEETVAAIMDIKFQNIVIEILIENHEKIF 568
V + K+NLM NLG+VFGPTL+R P+ + +AA+ DI++Q +V+E+LI+N + +F
Sbjct: 402 KRVTLHEKENLMNAENLGIVFGPTLMRSPELDAMAALNDIRYQRLVVELLIKNEDILF 459
>gi|209364623 chimerin (chimaerin) 1 isoform b [Homo sapiens]
Length = 433
Score = 126 bits (317), Expect = 7e-29
Identities = 63/178 (35%), Positives = 108/178 (60%), Gaps = 3/178 (1%)
Query: 392 IIRKCIHAVETRGINEQGLYRIVGVNSRVQKLLSVLMDPKTASETETDICAEWEIKTITS 451
++ CI +E+RG+N +GLYR+ G + ++ + + + + + +I IT
Sbjct: 258 VVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAF--DRDGEKADISVNMYEDINIITG 315
Query: 452 ALKTYLRMLPGPLMMYQFQRSFIKAAKLENQESRVSEIHSLVHRLPEKNRQMLQLLMNHL 511
ALK Y R LP PL+ Y FI++AK+ + + ++ +H + LP + + L+ LM HL
Sbjct: 316 ALKLYFRDLPIPLITYDAYPKFIESAKIMDPDEQLETLHEALKLLPPAHCETLRYLMAHL 375
Query: 512 ANVANNHKQNLMTVANLGVVFGPTLLR-PQEETVAAIMDIKFQNIVIEILIENHEKIF 568
V + K+NLM NLG+VFGPTL+R P+ + +AA+ DI++Q +V+E+LI+N + +F
Sbjct: 376 KRVTLHEKENLMNAENLGIVFGPTLMRSPELDAMAALNDIRYQRLVVELLIKNEDILF 433
>gi|218563749 ArfGAP with coiled-coil, ankyrin repeat and PH domains
3 [Homo sapiens]
Length = 834
Score = 123 bits (309), Expect = 6e-28
Identities = 113/451 (25%), Positives = 196/451 (43%), Gaps = 45/451 (9%)
Query: 6 LEFSDCCLDSPHFRETLKSHEAELDKTNKFIKELIKDGKSLISALKNLSSAKRKFADSLN 65
+EF +C DSP FR T+ E ++ + + +L+K ++ A K S R F +
Sbjct: 3 VEFEECVKDSPRFRATIDEVETDVVEIEAKLDKLVKLCSGMVEAGKAYVSTSRLFVSGVR 62
Query: 66 EFKFQCIGDAETDDEMCIARSLQEFATVLRNLEDERIRMIENASEVLITPLEKFRKEQIG 125
+ QC GD I+ LQ FA L+ + + + + + A + L+ F KE +
Sbjct: 63 DLSQQCQGDT------VISECLQRFADSLQEVVNYHMILFDQAQRSVRQQLQSFVKEDVR 116
Query: 126 AAKEAKKKYDKETEKYCGILEKHLNLSSKKKESQLQEADSQVDLVRQHFYEVSLEYVFKV 185
KE KK++DK E L ++ + + + +++EA + L R+ F ++L+YV ++
Sbjct: 117 KFKETKKQFDKVREDLELSLVRNAQ-APRHRPHEVEEATGALTLTRKCFRHLALDYVLQI 175
Query: 186 QEVQERKMFEFVEPLLAFLQGLFTFYHHGYELAKDFGDFK-------TQLTISIQNTRNR 238
+Q +K FE ++ +L+F+ +F+ GY L + QL I +
Sbjct: 176 NVLQAKKKFEILDSMLSFMHAQSSFFQQGYSLLHQLDPYMKKLAAELDQLVIDSAVEKRE 235
Query: 239 FEGTRSEVE--SLMKKMK--ENPLEHKTISP--YTMEGYLYVQEKRHFGTSWVKHY---- 288
E + ++ +L++ E+ +E +P MEGYL+ + F T W + +
Sbjct: 236 MERKHAAIQQRTLLQDFSYDESKVEFDVDAPSGVVMEGYLFKRASNAFKT-WNRRWFSIQ 294
Query: 289 ---CTYQRDSKQITMVPFDQKSGGKGGEDESVILKSCTRRKTDSIEKRFCFDVEAVDRPG 345
YQ+ K V D L+ C+ + + IE+RFCF+V + +
Sbjct: 295 NSQLVYQKKLKDALTVVVDD-------------LRLCSVKPCEDIERRFCFEVLSPTKS- 340
Query: 346 VITMQALSEEDRRLWMEAMDGR-EPVYNSNKDS-QSEGTAQLDSIGFSIIRKCIHAVETR 403
+QA SE+ R+ W++A+ Y + DS SE + S S I E
Sbjct: 341 -CMLQADSEKLRQAWVQAVQASIASAYRESPDSCYSERLDRTASPSTSSIDSATDTRERG 399
Query: 404 GINEQGLYRIVGVNSRVQKLLSVLMDPKTAS 434
E L R+ V Q DP+ AS
Sbjct: 400 VKGESVLQRVQSVAGNSQCGDCGQPDPRWAS 430
>gi|187608516 centaurin, beta 2 [Homo sapiens]
Length = 778
Score = 121 bits (303), Expect = 3e-27
Identities = 102/441 (23%), Positives = 198/441 (44%), Gaps = 31/441 (7%)
Query: 6 LEFSDCCLDSPHFRETLKSHEAELDKTNKFIKELIKDGKSLISALKNLSSAKRKFADSLN 65
++F +C DSP FR L+ E ++ + + +L+K ++I K A ++F + +
Sbjct: 5 VDFEECLKDSPRFRAALEEVEGDVAELELKLDKLVKLCIAMIDTGKAFCVANKQFMNGIR 64
Query: 66 EFKFQCIGDAETDDEMCIARSLQEFATVLRNLEDERIRMIENASEVLITPLEKFRKEQIG 125
+ DA + SL +F+ L+ + + + + + L+ F KE +
Sbjct: 65 DLAQYSSNDA------VVETSLTKFSDSLQEMINFHTILFDQTQRSIKAQLQNFVKEDLR 118
Query: 126 AAKEAKKKYDKETEKYCGILEKHLNLSSKKKESQLQEADSQVDLVRQHFYEVSLEYVFKV 185
K+AKK+++K +E+ L K+ + + K+ +++EA + + R+ F ++L+YV ++
Sbjct: 119 KFKDAKKQFEKVSEEKENALVKNAQVQ-RNKQHEVEEATNILTATRKCFRHIALDYVLQI 177
Query: 186 QEVQERKMFEFVEPLLAFLQGLFTFYHHGYEL-------AKDFGDFKTQLTISIQNTRNR 238
+Q ++ E ++ +L+F+ F+H GY+L KD G +L + +
Sbjct: 178 NVLQSKRRSEILKSMLSFMYAHLAFFHQGYDLFSELGPYMKDLGAQLDRLVVDAAKEKRE 237
Query: 239 FEGTRSEVESLMKKMKENPLEHK--TISPYTMEGYLYVQEKRHFGTSWVKHYCTYQRDSK 296
E S ++ ++ LE+ + MEGYL+ + F T W + + + Q +
Sbjct: 238 MEQKHSTIQQKDFSSDDSKLEYNVDAANGIVMEGYLFKRASNAFKT-WNRRWFSIQNNQL 296
Query: 297 QITMVPFDQKSGGKGGEDESVI---LKSCTRRKTDSIEKRFCFDVEAVDRPGVITMQALS 353
QK K ++ +V+ L+ CT + + IE+RFCF+V V +QA S
Sbjct: 297 VY------QK---KFKDNPTVVVEDLRLCTVKHCEDIERRFCFEV--VSPTKSCMLQADS 345
Query: 354 EEDRRLWMEAMDGREPVYNSNKDSQSEGTAQLDSIGFSIIRKCIHAVETRGINEQGLYRI 413
E+ R+ W++A+ K +SE + S + + E E L R+
Sbjct: 346 EKLRQAWIKAVQTSIATAYREKGDESEKLDKKSSPSTGSLDSGNESKEKLLKGESALQRV 405
Query: 414 VGVNSRVQKLLSVLMDPKTAS 434
+ L DP+ AS
Sbjct: 406 QCIPGNASCCDCGLADPRWAS 426
>gi|226693398 Rho GTPase activating protein 27 isoform b [Homo
sapiens]
Length = 521
Score = 120 bits (302), Expect = 4e-27
Identities = 70/178 (39%), Positives = 101/178 (56%), Gaps = 7/178 (3%)
Query: 393 IRKCIHAVETRGINEQGLYRIVGVNSRVQKLLSVLMDPKTASETETDIC-AEWE-IKTIT 450
+++CI AVE RG++ GLYRI G + +QKL K + D+ WE + IT
Sbjct: 346 VQQCIRAVEARGLDIDGLYRISGNLATIQKLRY-----KVDHDERLDLDDGRWEDVHVIT 400
Query: 451 SALKTYLRMLPGPLMMYQFQRSFIKAAKLENQESRVSEIHSLVHRLPEKNRQMLQLLMNH 510
ALK + R LP PL + R FI A KL++Q R + LV LP N L++L H
Sbjct: 401 GALKLFFRELPEPLFPFSHFRQFIAAIKLQDQARRSRCVRDLVRSLPAPNHDTLRMLFQH 460
Query: 511 LANVANNHKQNLMTVANLGVVFGPTLLRPQEETVAAIMDIKFQNIVIEILIENHEKIF 568
L V + +QN M+V ++ +VFGPTLLRP+ E + M + FQN V+E++++ IF
Sbjct: 461 LCRVIEHGEQNRMSVQSVAIVFGPTLLRPEVEETSMPMTMVFQNQVVELILQQCADIF 518
>gi|40548322 Rho GTPase activating protein 27 isoform a [Homo
sapiens]
Length = 548
Score = 120 bits (302), Expect = 4e-27
Identities = 70/178 (39%), Positives = 101/178 (56%), Gaps = 7/178 (3%)
Query: 393 IRKCIHAVETRGINEQGLYRIVGVNSRVQKLLSVLMDPKTASETETDIC-AEWE-IKTIT 450
+++CI AVE RG++ GLYRI G + +QKL K + D+ WE + IT
Sbjct: 373 VQQCIRAVEARGLDIDGLYRISGNLATIQKLRY-----KVDHDERLDLDDGRWEDVHVIT 427
Query: 451 SALKTYLRMLPGPLMMYQFQRSFIKAAKLENQESRVSEIHSLVHRLPEKNRQMLQLLMNH 510
ALK + R LP PL + R FI A KL++Q R + LV LP N L++L H
Sbjct: 428 GALKLFFRELPEPLFPFSHFRQFIAAIKLQDQARRSRCVRDLVRSLPAPNHDTLRMLFQH 487
Query: 511 LANVANNHKQNLMTVANLGVVFGPTLLRPQEETVAAIMDIKFQNIVIEILIENHEKIF 568
L V + +QN M+V ++ +VFGPTLLRP+ E + M + FQN V+E++++ IF
Sbjct: 488 LCRVIEHGEQNRMSVQSVAIVFGPTLLRPEVEETSMPMTMVFQNQVVELILQQCADIF 545
>gi|26986534 Rho GTPase activating protein 12 [Homo sapiens]
Length = 846
Score = 108 bits (270), Expect = 2e-23
Identities = 59/177 (33%), Positives = 100/177 (56%), Gaps = 6/177 (3%)
Query: 393 IRKCIHAVETRGINEQGLYRIVGVNSRVQKLLSVLMDPKTASETETDICAEWE-IKTITS 451
++ CI VE G++ G+YR+ G + +QKL + + ++ +WE I IT
Sbjct: 673 VKLCIEHVEEHGLDIDGIYRVSGNLAVIQKLRFAVNHDEKLDLNDS----KWEDIHVITG 728
Query: 452 ALKTYLRMLPGPLMMYQFQRSFIKAAKLENQESRVSEIHSLVHRLPEKNRQMLQLLMNHL 511
ALK + R LP PL + F+ A K E ++ RV+ + L+ +LP+ N+ +Q+L HL
Sbjct: 729 ALKMFFRELPEPLFTFNHFNDFVNAIKQEPRQ-RVAAVKDLIRQLPKPNQDTMQILFRHL 787
Query: 512 ANVANNHKQNLMTVANLGVVFGPTLLRPQEETVAAIMDIKFQNIVIEILIENHEKIF 568
V N ++N MT ++ +VFGPTLL+P++ET + +QN ++E+++ IF
Sbjct: 788 RRVIENGEKNRMTYQSIAIVFGPTLLKPEKETGNIAVHTVYQNQIVELILLELSSIF 844
>gi|47834348 minor histocompatibility antigen HA-1 [Homo sapiens]
Length = 1136
Score = 104 bits (260), Expect = 3e-22
Identities = 71/214 (33%), Positives = 108/214 (50%), Gaps = 32/214 (14%)
Query: 386 DSIGFSIIRKCIHAVETRGINEQGLYRIVGVNSRVQKLLSVLMDPKTASETETDICAEWE 445
D + F I++KC+ +E R + +G+YR+ GV +RV+KL + K E ++
Sbjct: 772 DGVPF-IVKKCVCEIERRALRTKGIYRVNGVKTRVEKLCQAFENGKELVEL-----SQAS 825
Query: 446 IKTITSALKTYLRMLPGPLMMYQFQRSFI-------------KAAKLENQESRVSE---- 488
I++ LK YLR LP PL+ ++ + KAA Q+ SE
Sbjct: 826 PHDISNVLKLYLRQLPEPLISFRLYHELVGLAKDSLKAEAEAKAASRGRQDGSESEAVAV 885
Query: 489 -----IHSLVHRLPEKNRQMLQLLMNHLANVANNHKQNLMTVANLGVVFGPTLLRPQ--E 541
+ L+ LP +NR LQ L+ HL + + N MT NLG+VFGPTLLRP+ E
Sbjct: 886 ALAGRLRELLRDLPPENRASLQYLLRHLRRIVEVEQDNKMTPGNLGIVFGPTLLRPRPTE 945
Query: 542 ETV--AAIMDIKFQNIVIEILIENHEKIFNTVPD 573
TV ++++D Q VIE LI ++ +F P+
Sbjct: 946 ATVSLSSLVDYPHQARVIETLIVHYGLVFEEEPE 979
Score = 30.8 bits (68), Expect = 4.9
Identities = 38/166 (22%), Positives = 67/166 (40%), Gaps = 12/166 (7%)
Query: 4 PALEFSDC-CLDSPHFRETLKSHEAELDKTNKFIKELIKDGKSLISALKNLSSAKRKFAD 62
P+LE D CL + L+ E +D + K + K K LIS L+ ++ + +FA
Sbjct: 256 PSLEDCDAGCLPAEEVDVLLQRCEGGVDAALLYAKNMAKYMKDLISYLEKRTTLEMEFAK 315
Query: 63 SLNEFKFQCIGDAETDDEMCIARSLQEFATVLRNLEDERIRMIENA----SEVLITPLEK 118
L + C + M + L ++ L + M++ ++ + PL
Sbjct: 316 GLQKIAHNCRQSVMQEPHMPL---LSIYSLALEQDLEFGHSMVQAVGTLQTQTFMQPLTL 372
Query: 119 FRKEQIGAAKEAKKKYDKETEKYCGILEKHLNLSSKKKESQLQEAD 164
R E KE K+ + + K + E NL K K+ +Q +
Sbjct: 373 RRLEHEKRRKEIKEAWHRAQRK---LQEAESNL-RKAKQGYVQRCE 414
>gi|150417981 glucocorticoid receptor DNA binding factor 1 [Homo
sapiens]
Length = 1499
Score = 104 bits (259), Expect = 3e-22
Identities = 51/180 (28%), Positives = 97/180 (53%), Gaps = 4/180 (2%)
Query: 393 IRKCIHAVETRGINEQGLYRIVGVNSRVQKLLSVLMDPKTASETETDICAEWEIKTITSA 452
I +CI +E G++ +G+YR+ G S ++ L E D + + T+ A
Sbjct: 1265 IERCIEYIEATGLSTEGIYRVSGNKSEMESLQRQFDQDHNLDLAEKD----FTVNTVAGA 1320
Query: 453 LKTYLRMLPGPLMMYQFQRSFIKAAKLENQESRVSEIHSLVHRLPEKNRQMLQLLMNHLA 512
+K++ LP PL+ Y Q ++A K+ ++E ++ + ++ + P++N ++ + +++HL
Sbjct: 1321 MKSFFSELPDPLVPYNMQIDLVEAHKINDREQKLHALKEVLKKFPKENHEVFKYVISHLN 1380
Query: 513 NVANNHKQNLMTVANLGVVFGPTLLRPQEETVAAIMDIKFQNIVIEILIENHEKIFNTVP 572
V++N+K NLMT NL + F PTL+RP T+ A+ + +IE+ I+ F P
Sbjct: 1381 KVSHNNKVNLMTSENLSICFWPTLMRPDFSTMDALTATRTYQTIIELFIQQCPFFFYNRP 1440
>gi|122939147 Rho GTPase activating protein 9 isoform 1 [Homo
sapiens]
Length = 731
Score = 103 bits (257), Expect = 6e-22
Identities = 66/194 (34%), Positives = 100/194 (51%), Gaps = 17/194 (8%)
Query: 391 SIIRKCIHAVETRGINEQGLYRIVGVNSRVQKLLSVLMDPKTA--------------SET 436
S +R CI AV+ RG++ G+YR+ G + VQKL L+D + A E
Sbjct: 538 SFLRLCIAAVDKRGLDVDGIYRVSGNLAVVQKL-RFLVDRERAVTSDGRYVFPEQPGQEG 596
Query: 437 ETDI-CAEWE-IKTITSALKTYLRMLPGPLMMYQFQRSFIKAAKLENQESRVSEIHSLVH 494
D+ EW+ I +T ALK +LR LP PL+ F A L E +S+I L+
Sbjct: 597 RLDLDSTEWDDIHVVTGALKLFLRELPQPLVPPLLLPHFRAALALSESEQCLSQIQELIG 656
Query: 495 RLPEKNRQMLQLLMNHLANVANNHKQNLMTVANLGVVFGPTLLRPQEETVAAIMDIKFQN 554
+P+ N L+ L+ HL V + +N MT NLG+VFGPTL RP++ET +
Sbjct: 657 SMPKPNHDTLRYLLEHLCRVIAHSDKNRMTPHNLGIVFGPTLFRPEQETSDPAAHALYPG 716
Query: 555 IVIEILIENHEKIF 568
++++++ N +F
Sbjct: 717 QLVQLMLTNFTSLF 730
>gi|122939149 Rho GTPase activating protein 9 isoform 3 [Homo
sapiens]
Length = 547
Score = 103 bits (257), Expect = 6e-22
Identities = 66/194 (34%), Positives = 100/194 (51%), Gaps = 17/194 (8%)
Query: 391 SIIRKCIHAVETRGINEQGLYRIVGVNSRVQKLLSVLMDPKTA--------------SET 436
S +R CI AV+ RG++ G+YR+ G + VQKL L+D + A E
Sbjct: 354 SFLRLCIAAVDKRGLDVDGIYRVSGNLAVVQKL-RFLVDRERAVTSDGRYVFPEQPGQEG 412
Query: 437 ETDI-CAEWE-IKTITSALKTYLRMLPGPLMMYQFQRSFIKAAKLENQESRVSEIHSLVH 494
D+ EW+ I +T ALK +LR LP PL+ F A L E +S+I L+
Sbjct: 413 RLDLDSTEWDDIHVVTGALKLFLRELPQPLVPPLLLPHFRAALALSESEQCLSQIQELIG 472
Query: 495 RLPEKNRQMLQLLMNHLANVANNHKQNLMTVANLGVVFGPTLLRPQEETVAAIMDIKFQN 554
+P+ N L+ L+ HL V + +N MT NLG+VFGPTL RP++ET +
Sbjct: 473 SMPKPNHDTLRYLLEHLCRVIAHSDKNRMTPHNLGIVFGPTLFRPEQETSDPAAHALYPG 532
Query: 555 IVIEILIENHEKIF 568
++++++ N +F
Sbjct: 533 QLVQLMLTNFTSLF 546
>gi|203097003 Rho GTPase activating protein 21 [Homo sapiens]
Length = 1958
Score = 103 bits (256), Expect = 8e-22
Identities = 65/205 (31%), Positives = 106/205 (51%), Gaps = 10/205 (4%)
Query: 392 IIRKCIHAVETRGINEQGLYRIVGVNSRVQKLLSVLMDPKTASETETDICAEW-EIKTIT 450
I+ C VE RG+ G+YR+ G N+ + + L + + D +W ++ I+
Sbjct: 1164 IVDICCKLVEERGLEYTGIYRVPGNNAAISSMQEELNKGMADIDIQDD---KWRDLNVIS 1220
Query: 451 SALKTYLRMLPGPLMMYQFQRSFIKAAKLENQESRVSEIHSLVHRLPEKNRQMLQLLMNH 510
S LK++ R LP PL FI+A + E+ R+ + L+H LPE + + L+ L H
Sbjct: 1221 SLLKSFFRKLPEPLFTNDKYADFIEANRKEDPLDRLKTLKRLIHDLPEHHYETLKFLSAH 1280
Query: 511 LANVANNHKQNLMTVANLGVVFGPTLLRPQEETVA-AIMDIKFQNIVIEILIENHEKIFN 569
L VA N ++N M NL +VFGPTL+R E+ + + + Q ++E LI++H+ F
Sbjct: 1281 LKTVAENSEKNKMEPRNLAIVFGPTLVRTSEDNMTHMVTHMPDQYKIVETLIQHHDWFFT 1340
Query: 570 TV-PDMPLTNAQLHLSRKKSSDSKP 593
+ PLT Q + + DS+P
Sbjct: 1341 EEGAEEPLTTVQ----EESTVDSQP 1361
>gi|186910302 Rac GTPase activating protein 1 [Homo sapiens]
Length = 632
Score = 102 bits (254), Expect = 1e-21
Identities = 63/175 (36%), Positives = 100/175 (57%), Gaps = 10/175 (5%)
Query: 391 SIIRKCIHAVETRGINEQGLYRIVGVNSRVQKLLSVLMDPKTASE-TETDICAEWEIKTI 449
SI+ C++ +E RG+ E GLYRI G + V++L + KT ++ D +I I
Sbjct: 364 SIVVHCVNEIEQRGLTETGLYRISGCDRTVKELKEKFLRVKTVPLLSKVD-----DIHAI 418
Query: 450 TSALKTYLRMLPGPLMMYQFQRSFIKAAKLENQESRVSEIHSLVHRLPEKNRQMLQLLMN 509
S LK +LR L PL+ ++ R+F++AA++ ++++ ++ ++ V LP+ NR L LM
Sbjct: 419 CSLLKDFLRNLKEPLLTFRLNRAFMEAAEITDEDNSIAAMYQAVGELPQANRDTLAFLMI 478
Query: 510 HLANVANNHKQNLMTVANLGVVFGPTLLR---PQEETVAAIMDIKFQNIVIEILI 561
HL VA + M VANL VFGPT++ P + V + DIK Q V+E L+
Sbjct: 479 HLQRVAQS-PHTKMDVANLAKVFGPTIVAHAVPNPDPVTMLQDIKRQPKVVERLL 532
>gi|186910300 Rac GTPase activating protein 1 [Homo sapiens]
Length = 632
Score = 102 bits (254), Expect = 1e-21
Identities = 63/175 (36%), Positives = 100/175 (57%), Gaps = 10/175 (5%)
Query: 391 SIIRKCIHAVETRGINEQGLYRIVGVNSRVQKLLSVLMDPKTASE-TETDICAEWEIKTI 449
SI+ C++ +E RG+ E GLYRI G + V++L + KT ++ D +I I
Sbjct: 364 SIVVHCVNEIEQRGLTETGLYRISGCDRTVKELKEKFLRVKTVPLLSKVD-----DIHAI 418
Query: 450 TSALKTYLRMLPGPLMMYQFQRSFIKAAKLENQESRVSEIHSLVHRLPEKNRQMLQLLMN 509
S LK +LR L PL+ ++ R+F++AA++ ++++ ++ ++ V LP+ NR L LM
Sbjct: 419 CSLLKDFLRNLKEPLLTFRLNRAFMEAAEITDEDNSIAAMYQAVGELPQANRDTLAFLMI 478
Query: 510 HLANVANNHKQNLMTVANLGVVFGPTLLR---PQEETVAAIMDIKFQNIVIEILI 561
HL VA + M VANL VFGPT++ P + V + DIK Q V+E L+
Sbjct: 479 HLQRVAQS-PHTKMDVANLAKVFGPTIVAHAVPNPDPVTMLQDIKRQPKVVERLL 532
>gi|21361397 Rac GTPase activating protein 1 [Homo sapiens]
Length = 632
Score = 102 bits (254), Expect = 1e-21
Identities = 63/175 (36%), Positives = 100/175 (57%), Gaps = 10/175 (5%)
Query: 391 SIIRKCIHAVETRGINEQGLYRIVGVNSRVQKLLSVLMDPKTASE-TETDICAEWEIKTI 449
SI+ C++ +E RG+ E GLYRI G + V++L + KT ++ D +I I
Sbjct: 364 SIVVHCVNEIEQRGLTETGLYRISGCDRTVKELKEKFLRVKTVPLLSKVD-----DIHAI 418
Query: 450 TSALKTYLRMLPGPLMMYQFQRSFIKAAKLENQESRVSEIHSLVHRLPEKNRQMLQLLMN 509
S LK +LR L PL+ ++ R+F++AA++ ++++ ++ ++ V LP+ NR L LM
Sbjct: 419 CSLLKDFLRNLKEPLLTFRLNRAFMEAAEITDEDNSIAAMYQAVGELPQANRDTLAFLMI 478
Query: 510 HLANVANNHKQNLMTVANLGVVFGPTLLR---PQEETVAAIMDIKFQNIVIEILI 561
HL VA + M VANL VFGPT++ P + V + DIK Q V+E L+
Sbjct: 479 HLQRVAQS-PHTKMDVANLAKVFGPTIVAHAVPNPDPVTMLQDIKRQPKVVERLL 532
>gi|218083800 Rho GTPase-activating protein isoform 1 [Homo sapiens]
Length = 2087
Score = 101 bits (252), Expect = 2e-21
Identities = 87/333 (26%), Positives = 144/333 (43%), Gaps = 31/333 (9%)
Query: 392 IIRKCIHAVETRGINEQGLYRIVGVNSRVQKLLSVLMDPKTASETETDICAE---WEIKT 448
+++ C +E GI + G+YR+ GV S +Q+L + SE D+ E +I +
Sbjct: 388 VLQSCTAFIERYGIVD-GIYRLSGVASNIQRLRH-----EFDSEHVPDLTKEPYVQDIHS 441
Query: 449 ITSALKTYLRMLPGPLMMYQFQRSFIKAAKLENQESRVSEIHSLVHRLPEKNRQMLQLLM 508
+ S K Y R LP PL+ YQ F A E R+ +IH ++ +LP + + L+ LM
Sbjct: 442 VGSLCKLYFRELPNPLLTYQLYEKFSDAVSAATDEERLIKIHDVIQQLPPPHYRTLEFLM 501
Query: 509 NHLANVANNHKQNLMTVANLGVVFGPTLLRPQE------ETVAAIMDIKFQNIVIEILIE 562
HL+ +A+ M NL +V+ P LLR ++ AA M+++ Q++V+E ++
Sbjct: 502 RHLSLLADYCSITNMHAKNLAIVWAPNLLRSKQIESACFSGTAAFMEVRIQSVVVEFILN 561
Query: 563 NHEKIFNTVPDMPLTNAQLHLSRKKSSDSKPPSCSERPLTLFHTVQSTEKQEQRNSIINS 622
+ + +F+ M + LSR KS P S + LTL T+ Q + +
Sbjct: 562 HVDVLFSGRISMAMQEGAASLSRPKSLLVSSP--STKLLTLEEAQARTQAQVNSPIVTEN 619
Query: 623 SLESVSSNPNSILNSSSSLQPNMNSSDPDLAVVKPTRPNSLPPNPSPTSPLSPSWPMFSA 682
V P ++LQ ++ +++ P N SP+ SW F
Sbjct: 620 KYIEVGEGP-------AALQGKFHT------IIEFPLERKRPQNKMKKSPVG-SWRSFFN 665
Query: 683 PSSPMPTSSTSSDSSPVSTPFRKAKALYACKAE 715
S + KA AL +AE
Sbjct: 666 LGKSSSVSKRKLQRNESEPSEMKAMALKGGRAE 698
>gi|29469071 Rho GTPase-activating protein isoform 2 [Homo sapiens]
Length = 1738
Score = 101 bits (252), Expect = 2e-21
Identities = 87/333 (26%), Positives = 144/333 (43%), Gaps = 31/333 (9%)
Query: 392 IIRKCIHAVETRGINEQGLYRIVGVNSRVQKLLSVLMDPKTASETETDICAE---WEIKT 448
+++ C +E GI + G+YR+ GV S +Q+L + SE D+ E +I +
Sbjct: 39 VLQSCTAFIERYGIVD-GIYRLSGVASNIQRLRH-----EFDSEHVPDLTKEPYVQDIHS 92
Query: 449 ITSALKTYLRMLPGPLMMYQFQRSFIKAAKLENQESRVSEIHSLVHRLPEKNRQMLQLLM 508
+ S K Y R LP PL+ YQ F A E R+ +IH ++ +LP + + L+ LM
Sbjct: 93 VGSLCKLYFRELPNPLLTYQLYEKFSDAVSAATDEERLIKIHDVIQQLPPPHYRTLEFLM 152
Query: 509 NHLANVANNHKQNLMTVANLGVVFGPTLLRPQE------ETVAAIMDIKFQNIVIEILIE 562
HL+ +A+ M NL +V+ P LLR ++ AA M+++ Q++V+E ++
Sbjct: 153 RHLSLLADYCSITNMHAKNLAIVWAPNLLRSKQIESACFSGTAAFMEVRIQSVVVEFILN 212
Query: 563 NHEKIFNTVPDMPLTNAQLHLSRKKSSDSKPPSCSERPLTLFHTVQSTEKQEQRNSIINS 622
+ + +F+ M + LSR KS P S + LTL T+ Q + +
Sbjct: 213 HVDVLFSGRISMAMQEGAASLSRPKSLLVSSP--STKLLTLEEAQARTQAQVNSPIVTEN 270
Query: 623 SLESVSSNPNSILNSSSSLQPNMNSSDPDLAVVKPTRPNSLPPNPSPTSPLSPSWPMFSA 682
V P ++LQ ++ +++ P N SP+ SW F
Sbjct: 271 KYIEVGEGP-------AALQGKFHT------IIEFPLERKRPQNKMKKSPVG-SWRSFFN 316
Query: 683 PSSPMPTSSTSSDSSPVSTPFRKAKALYACKAE 715
S + KA AL +AE
Sbjct: 317 LGKSSSVSKRKLQRNESEPSEMKAMALKGGRAE 349
>gi|186928844 Cdc42 GTPase-activating protein [Homo sapiens]
Length = 1444
Score = 99.8 bits (247), Expect = 9e-21
Identities = 78/294 (26%), Positives = 139/294 (47%), Gaps = 47/294 (15%)
Query: 392 IIRKCIHAVETRGINEQGLYRIVGVNSRVQKLLSVLMDPKTASETETDICAE---WEIKT 448
+++ C +ET GI + G+YR+ GV S +Q+L + S+ D+ E +I
Sbjct: 37 VLKSCAEFIETHGIVD-GIYRLSGVTSNIQRLRQ-----EFGSDQCPDLTREVYLQDIHC 90
Query: 449 ITSALKTYLRMLPGPLMMYQFQRSFIKAAKLENQESRVSEIHSLVHRLPEKNRQMLQLLM 508
+ S K Y R LP PL+ Y+ F +A +E +++ I +++ LP + + L+ L+
Sbjct: 91 VGSLCKLYFRELPNPLLTYELYEKFTEAVSHCPEEGQLARIQNVIQELPPSHYRTLEYLI 150
Query: 509 NHLANVANNHKQNLMTVANLGVVFGPTLLRPQEETV------AAIMDIKFQNIVIEILIE 562
HLA++A+ + M NL +V+ P LLR +E AA + ++ Q +VIE ++
Sbjct: 151 RHLAHIASFSSKTNMHARNLALVWAPNLLRSKEIEATGCNGDAAFLAVRVQQVVIEFILN 210
Query: 563 NHEKIFN-------------------TVP--DMPLTNAQLHLSRKKSSDSKPPSCSER-- 599
+ ++IFN T+P +P+ L ++ +S + P+ ER
Sbjct: 211 HVDQIFNNGAPGSLENDENRPIMKSLTLPALSLPMKLVSLEEAQARSLATNHPARKERRE 270
Query: 600 --------PL-TLFHTVQSTEKQEQRNSIINSSLESVSSNPNSILNSSSSLQPN 644
P+ TLFHTV +++ S + +S+ + S +S S L N
Sbjct: 271 NSLPEIVPPMGTLFHTVLELPDNKRKLSSKSKKWKSIFNLGRSGSDSKSKLSRN 324
>gi|23510413 sorting nexin 26 [Homo sapiens]
Length = 1126
Score = 97.1 bits (240), Expect = 6e-20
Identities = 56/184 (30%), Positives = 101/184 (54%), Gaps = 9/184 (4%)
Query: 392 IIRKCIHAVETRGINEQGLYRIVGVNSRVQKLLSVLMDPKTASETETDICAEWEIKTITS 451
++R C +E G+ + G+YR+ GV+S +Q+L D + E + +I +++S
Sbjct: 331 VLRCCSEFIEAHGVVD-GIYRLSGVSSNIQRLRHEF-DSERIPELSGPAFLQ-DIHSVSS 387
Query: 452 ALKTYLRMLPGPLMMYQFQRSFIKAAKLENQESRVSEIHSLVHRLPEKNRQMLQLLMNHL 511
K Y R LP PL+ YQ F +A + +E R+ +H ++ +LP + + L+ L+ HL
Sbjct: 388 LCKLYFRELPNPLLTYQLYGKFSEAMSVPGEEERLVRVHDVIQQLPPPHYRTLEYLLRHL 447
Query: 512 ANVANNHKQNLMTVANLGVVFGPTLLRPQE-ETV-----AAIMDIKFQNIVIEILIENHE 565
A +A + M NL +V+ P LLR E E+V AA +++ Q++V+E L+ + +
Sbjct: 448 ARMARHSANTSMHARNLAIVWAPNLLRSMELESVGMGGAAAFREVRVQSVVVEFLLTHVD 507
Query: 566 KIFN 569
+F+
Sbjct: 508 VLFS 511
>gi|82546845 breakpoint cluster region isoform 2 [Homo sapiens]
Length = 1227
Score = 95.1 bits (235), Expect = 2e-19
Identities = 52/151 (34%), Positives = 83/151 (54%), Gaps = 3/151 (1%)
Query: 392 IIRKCIHAVETRGINEQGLYRIVGVNSRVQKLLSVLMDPKTASETETDICAEWEIKTITS 451
I+R+C+ +E RG+ E G+YR+ GV + +Q L + ++ + + +E ++ I
Sbjct: 1026 IVRQCVEEIERRGMEEVGIYRVSGVATDIQALKAAF---DVNNKDVSVMMSEMDVNAIAG 1082
Query: 452 ALKTYLRMLPGPLMMYQFQRSFIKAAKLENQESRVSEIHSLVHRLPEKNRQMLQLLMNHL 511
LK Y R LP PL +F +F + L + ++ S + +L+ LPE N L++HL
Sbjct: 1083 TLKLYFRELPEPLFTDEFYPNFAEGIALSDPVAKESCMLNLLLSLPEANLLTFLFLLDHL 1142
Query: 512 ANVANNHKQNLMTVANLGVVFGPTLLRPQEE 542
VA N M++ NL VFGPTLLRP E+
Sbjct: 1143 KRVAEKEAVNKMSLHNLATVFGPTLLRPSEK 1173
>gi|82546843 breakpoint cluster region isoform 1 [Homo sapiens]
Length = 1271
Score = 95.1 bits (235), Expect = 2e-19
Identities = 52/151 (34%), Positives = 83/151 (54%), Gaps = 3/151 (1%)
Query: 392 IIRKCIHAVETRGINEQGLYRIVGVNSRVQKLLSVLMDPKTASETETDICAEWEIKTITS 451
I+R+C+ +E RG+ E G+YR+ GV + +Q L + ++ + + +E ++ I
Sbjct: 1070 IVRQCVEEIERRGMEEVGIYRVSGVATDIQALKAAF---DVNNKDVSVMMSEMDVNAIAG 1126
Query: 452 ALKTYLRMLPGPLMMYQFQRSFIKAAKLENQESRVSEIHSLVHRLPEKNRQMLQLLMNHL 511
LK Y R LP PL +F +F + L + ++ S + +L+ LPE N L++HL
Sbjct: 1127 TLKLYFRELPEPLFTDEFYPNFAEGIALSDPVAKESCMLNLLLSLPEANLLTFLFLLDHL 1186
Query: 512 ANVANNHKQNLMTVANLGVVFGPTLLRPQEE 542
VA N M++ NL VFGPTLLRP E+
Sbjct: 1187 KRVAEKEAVNKMSLHNLATVFGPTLLRPSEK 1217
>gi|151108509 Rho GTPase-activating protein RICH2 [Homo sapiens]
Length = 818
Score = 94.7 bits (234), Expect = 3e-19
Identities = 91/371 (24%), Positives = 158/371 (42%), Gaps = 44/371 (11%)
Query: 393 IRKCIHAVETRGINEQGLYRIVGVNSRVQKLLSVLMDPKTASETETDICA------EWEI 446
I C+ + G+ E+GL+R+ S+++KL + L D C +
Sbjct: 272 IEACVTMLLECGMQEEGLFRVAPSASKLKKLKAAL-----------DCCVVDVQEYSADP 320
Query: 447 KTITSALKTYLRMLPGPLMMYQFQRSFIKAAKLENQESRVSEIHSLVHRLPEKNRQMLQL 506
I ALK+YLR LP PLM ++ +I+A+ ++ Q+ ++ + + +LP+ N ++
Sbjct: 321 HAIAGALKSYLRELPEPLMTFELYDEWIQASNVQEQDKKLQALWNACEKLPKANHNNIRY 380
Query: 507 LMNHLANVANNHKQNLMTVANLGVVFGPTLLRPQEE-TVAAIMDIKFQNIV--IEILIEN 563
L+ L+ ++ N MT +N+ +V GP LL PQ E + +M IV IE +I++
Sbjct: 381 LIKFLSKLSEYQDVNKMTPSNMAIVLGPNLLWPQAEGNITEMMTTVSLQIVGIIEPIIQH 440
Query: 564 HEKIFNTVPDMPLT---NAQLHLSRKKSSDSKP-----------PSCSERPLTLFHTVQS 609
+ F + +T + +H++ + S P P + RPL++
Sbjct: 441 ADWFFPGEIEFNITGNYGSPVHVNHNANYSSMPSPDMDPADRRQPEQARRPLSVATDNMM 500
Query: 610 TEKQEQRNSIINSSLESVSSNPNSILNSSSSLQPNMNSSDPDLAVVKPTRPNSLP-PNPS 668
E ++ S+ + N + SS ++ + P + P + P P+P
Sbjct: 501 LEFYKKDGLRKIQSMGVRVMDTNWVARRGSSAGRKVSCAPPSMQPPAPPAELAAPLPSPL 560
Query: 669 PTSPL-SPSWPMFSAPSSPMPTSSTSSDSSPVSTPFRKAKALYACKAEHDSELSFTAGTV 727
P PL SP+ P S S P T K+K L A+ S S + GT
Sbjct: 561 PEQPLDSPAAPALS-------PSGLGLQPGPERTSTTKSKELSPGSAQKGSPGS-SQGTA 612
Query: 728 FDNVHPSQEPG 738
P +PG
Sbjct: 613 CAGTQPGAQPG 623
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.130 0.369
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,020,520
Number of Sequences: 37866
Number of extensions: 1301437
Number of successful extensions: 12999
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 249
Number of HSP's successfully gapped in prelim test: 598
Number of HSP's that attempted gapping in prelim test: 9760
Number of HSP's gapped (non-prelim): 3285
length of query: 759
length of database: 18,247,518
effective HSP length: 110
effective length of query: 649
effective length of database: 14,082,258
effective search space: 9139385442
effective search space used: 9139385442
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.5 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.