Guide to the Human Genome
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Search of human proteins with 189458852

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|189458852 ORM1-like 1 [Homo sapiens]
         (153 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|189458852 ORM1-like 1 [Homo sapiens]                               315   7e-87
gi|7706009 ORM1-like 1 [Homo sapiens]                                 315   7e-87
gi|27544927 ORM1-like 3 [Homo sapiens]                                282   7e-77
gi|7661820 ORMDL2 [Homo sapiens]                                      277   3e-75
gi|116875852 HECT domain and ankyrin repeat containing, E3 ubiqu...    30   0.62 
gi|5031627 chemokine (C-C motif) receptor 4 [Homo sapiens]             30   0.81 
gi|239740701 PREDICTED: hypothetical protein [Homo sapiens]            29   1.8  
gi|126091152 cubilin [Homo sapiens]                                    28   2.3  
gi|122937404 membrane bound O-acyltransferase domain containing ...    28   2.3  
gi|4758568 heat shock transcription factor 2 isoform a [Homo sap...    28   4.0  
gi|239735592 TRAF2 and NCK interacting kinase isoform 8 [Homo sa...    27   6.8  
gi|239735590 TRAF2 and NCK interacting kinase isoform 7 [Homo sa...    27   6.8  
gi|239735588 TRAF2 and NCK interacting kinase isoform 6 [Homo sa...    27   6.8  
gi|239735586 TRAF2 and NCK interacting kinase isoform 5 [Homo sa...    27   6.8  
gi|239735584 TRAF2 and NCK interacting kinase isoform 4 [Homo sa...    27   6.8  
gi|239735582 TRAF2 and NCK interacting kinase isoform 3 [Homo sa...    27   6.8  
gi|239735580 TRAF2 and NCK interacting kinase isoform 2 [Homo sa...    27   6.8  
gi|55741807 TRAF2 and NCK interacting kinase isoform 1 [Homo sap...    27   6.8  
gi|21264602 laminin alpha 5 [Homo sapiens]                             27   6.8  

>gi|189458852 ORM1-like 1 [Homo sapiens]
          Length = 153

 Score =  315 bits (808), Expect = 7e-87
 Identities = 153/153 (100%), Positives = 153/153 (100%)

Query: 1   MNVGVAHSEVNPNTRVMNSRGMWLTYALGVGLLHIVLLSIPFFSVPVAWTLTNIIHNLGM 60
           MNVGVAHSEVNPNTRVMNSRGMWLTYALGVGLLHIVLLSIPFFSVPVAWTLTNIIHNLGM
Sbjct: 1   MNVGVAHSEVNPNTRVMNSRGMWLTYALGVGLLHIVLLSIPFFSVPVAWTLTNIIHNLGM 60

Query: 61  YVFLHAVKGTPFETPDQGKARLLTHWEQLDYGVQFTSSRKFFTISPIILYFLASFYTKYD 120
           YVFLHAVKGTPFETPDQGKARLLTHWEQLDYGVQFTSSRKFFTISPIILYFLASFYTKYD
Sbjct: 61  YVFLHAVKGTPFETPDQGKARLLTHWEQLDYGVQFTSSRKFFTISPIILYFLASFYTKYD 120

Query: 121 PTHFILNTASLLSVLIPKMPQLHGVRIFGINKY 153
           PTHFILNTASLLSVLIPKMPQLHGVRIFGINKY
Sbjct: 121 PTHFILNTASLLSVLIPKMPQLHGVRIFGINKY 153


>gi|7706009 ORM1-like 1 [Homo sapiens]
          Length = 153

 Score =  315 bits (808), Expect = 7e-87
 Identities = 153/153 (100%), Positives = 153/153 (100%)

Query: 1   MNVGVAHSEVNPNTRVMNSRGMWLTYALGVGLLHIVLLSIPFFSVPVAWTLTNIIHNLGM 60
           MNVGVAHSEVNPNTRVMNSRGMWLTYALGVGLLHIVLLSIPFFSVPVAWTLTNIIHNLGM
Sbjct: 1   MNVGVAHSEVNPNTRVMNSRGMWLTYALGVGLLHIVLLSIPFFSVPVAWTLTNIIHNLGM 60

Query: 61  YVFLHAVKGTPFETPDQGKARLLTHWEQLDYGVQFTSSRKFFTISPIILYFLASFYTKYD 120
           YVFLHAVKGTPFETPDQGKARLLTHWEQLDYGVQFTSSRKFFTISPIILYFLASFYTKYD
Sbjct: 61  YVFLHAVKGTPFETPDQGKARLLTHWEQLDYGVQFTSSRKFFTISPIILYFLASFYTKYD 120

Query: 121 PTHFILNTASLLSVLIPKMPQLHGVRIFGINKY 153
           PTHFILNTASLLSVLIPKMPQLHGVRIFGINKY
Sbjct: 121 PTHFILNTASLLSVLIPKMPQLHGVRIFGINKY 153


>gi|27544927 ORM1-like 3 [Homo sapiens]
          Length = 153

 Score =  282 bits (722), Expect = 7e-77
 Identities = 129/153 (84%), Positives = 142/153 (92%)

Query: 1   MNVGVAHSEVNPNTRVMNSRGMWLTYALGVGLLHIVLLSIPFFSVPVAWTLTNIIHNLGM 60
           MNVG AHSEVNPNTRVMNSRG+WL+Y L +GLLHIVLLSIPF SVPV WTLTN+IHN+GM
Sbjct: 1   MNVGTAHSEVNPNTRVMNSRGIWLSYVLAIGLLHIVLLSIPFVSVPVVWTLTNLIHNMGM 60

Query: 61  YVFLHAVKGTPFETPDQGKARLLTHWEQLDYGVQFTSSRKFFTISPIILYFLASFYTKYD 120
           Y+FLH VKGTPFETPDQGKARLLTHWEQ+DYGVQFT+SRKF TI+PI+LYFL SFYTKYD
Sbjct: 61  YIFLHTVKGTPFETPDQGKARLLTHWEQMDYGVQFTASRKFLTITPIVLYFLTSFYTKYD 120

Query: 121 PTHFILNTASLLSVLIPKMPQLHGVRIFGINKY 153
             HF+LNT SL+SVLIPK+PQLHGVRIFGINKY
Sbjct: 121 QIHFVLNTVSLMSVLIPKLPQLHGVRIFGINKY 153


>gi|7661820 ORMDL2 [Homo sapiens]
          Length = 153

 Score =  277 bits (708), Expect = 3e-75
 Identities = 127/153 (83%), Positives = 141/153 (92%)

Query: 1   MNVGVAHSEVNPNTRVMNSRGMWLTYALGVGLLHIVLLSIPFFSVPVAWTLTNIIHNLGM 60
           MNVGVAHSEVNPNTRVMNSRG+WL Y + VGLLH+VLLSIPFFS+PV WTLTN+IHNL  
Sbjct: 1   MNVGVAHSEVNPNTRVMNSRGIWLAYIILVGLLHMVLLSIPFFSIPVVWTLTNVIHNLAT 60

Query: 61  YVFLHAVKGTPFETPDQGKARLLTHWEQLDYGVQFTSSRKFFTISPIILYFLASFYTKYD 120
           YVFLH VKGTPFETPDQGKARLLTHWEQ+DYG+QFTSSRKF +ISPI+LY LASFYTKYD
Sbjct: 61  YVFLHTVKGTPFETPDQGKARLLTHWEQMDYGLQFTSSRKFLSISPIVLYLLASFYTKYD 120

Query: 121 PTHFILNTASLLSVLIPKMPQLHGVRIFGINKY 153
             HF++NTASLLSVL+PK+PQ HGVR+FGINKY
Sbjct: 121 AAHFLINTASLLSVLLPKLPQFHGVRVFGINKY 153


>gi|116875852 HECT domain and ankyrin repeat containing, E3
           ubiquitin protein ligase 1 [Homo sapiens]
          Length = 909

 Score = 30.4 bits (67), Expect = 0.62
 Identities = 33/123 (26%), Positives = 55/123 (44%), Gaps = 6/123 (4%)

Query: 26  YALGVGLLHIVLLSI-PFFSVPVAWTLTNIIHNLGMYVFLHA---VKGTPFETPDQ--GK 79
           + LG+ + +  + SI P ++  + W L N I +LG+ +       V G   E P +  G 
Sbjct: 669 HILGIPVNYQDVASIDPEYAKNLQWILDNDISDLGLELTFSVETDVFGAMEEVPLKPGGG 728

Query: 80  ARLLTHWEQLDYGVQFTSSRKFFTISPIILYFLASFYTKYDPTHFILNTASLLSVLIPKM 139
           + L+T   + +Y    T  R    I P I  FL  F+    P+   L     L +L+  M
Sbjct: 729 SILVTQNNKAEYVQLVTELRMTRAIQPQINAFLQGFHMFIPPSLIQLFDEYELELLLSGM 788

Query: 140 PQL 142
           P++
Sbjct: 789 PEI 791


>gi|5031627 chemokine (C-C motif) receptor 4 [Homo sapiens]
          Length = 360

 Score = 30.0 bits (66), Expect = 0.81
 Identities = 22/73 (30%), Positives = 31/73 (42%), Gaps = 15/73 (20%)

Query: 49  WTLTNIIHNLGMYVFLHAVKGTPFETPDQGKARLLTHWEQLDYGVQFTSSRKFF--TISP 106
           WT  NI+  L   V L  ++   FE               LDY +Q T +  F    ++P
Sbjct: 255 WTPYNIVLFLETLVELEVLQDCTFE-------------RYLDYAIQATETLAFVHCCLNP 301

Query: 107 IILYFLASFYTKY 119
           II +FL   + KY
Sbjct: 302 IIYFFLGEKFRKY 314


>gi|239740701 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 155

 Score = 28.9 bits (63), Expect = 1.8
 Identities = 11/32 (34%), Positives = 19/32 (59%)

Query: 29 GVGLLHIVLLSIPFFSVPVAWTLTNIIHNLGM 60
          G GL H  +  +P F +PV W+  + I ++G+
Sbjct: 26 GFGLFHSGIHDVPHFYLPVGWSRFSFIKSVGV 57


>gi|126091152 cubilin [Homo sapiens]
          Length = 3623

 Score = 28.5 bits (62), Expect = 2.3
 Identities = 18/66 (27%), Positives = 30/66 (45%), Gaps = 1/66 (1%)

Query: 10   VNPNTRVMNSRGMWLTYALGVGLLHIVLLSIPFFSVPVAWTLTNIIHNLGMYVFL-HAVK 68
            ++PN        M  TY +    L +VLL+   F +     +T    N G+++   ++V 
Sbjct: 2932 ISPNYPKQYDNNMNCTYVIEANPLSVVLLTFVSFHLEARSAVTGSCVNDGVHIIRGYSVM 2991

Query: 69   GTPFET 74
             TPF T
Sbjct: 2992 STPFAT 2997


>gi|122937404 membrane bound O-acyltransferase domain containing 1
           [Homo sapiens]
          Length = 495

 Score = 28.5 bits (62), Expect = 2.3
 Identities = 14/46 (30%), Positives = 25/46 (54%), Gaps = 1/46 (2%)

Query: 102 FTISPIILYFLASFYTKYDPTHFILNTASLLSVL-IPKMPQLHGVR 146
           +T++P ++  +    + Y   +F L+  SLL +L +P  PQ H  R
Sbjct: 436 YTVAPFVMLAVEPTISLYKSMYFYLHIISLLIILFLPMKPQAHTQR 481


>gi|4758568 heat shock transcription factor 2 isoform a [Homo
           sapiens]
          Length = 536

 Score = 27.7 bits (60), Expect = 4.0
 Identities = 18/56 (32%), Positives = 29/56 (51%), Gaps = 3/56 (5%)

Query: 78  GKARLLTHWEQLDYGV---QFTSSRKFFTISPIILYFLASFYTKYDPTHFILNTAS 130
           GK  LL + + +D  +   Q   S + F+I P +L  L +   + +PT +I NT S
Sbjct: 356 GKVELLDYLDSIDCSLEDFQAMLSGRQFSIDPDLLVDLFTSSVQMNPTDYINNTKS 411


>gi|239735592 TRAF2 and NCK interacting kinase isoform 8 [Homo
           sapiens]
          Length = 1268

 Score = 26.9 bits (58), Expect = 6.8
 Identities = 12/37 (32%), Positives = 23/37 (62%), Gaps = 3/37 (8%)

Query: 70  TPFETPDQGKARLLTHWEQLDYGVQF---TSSRKFFT 103
           +P  TP +G  R+ TH +++D G ++   +S++  FT
Sbjct: 846 SPAGTPTEGLGRVSTHSQEMDSGTEYGMGSSTKASFT 882


>gi|239735590 TRAF2 and NCK interacting kinase isoform 7 [Homo
           sapiens]
          Length = 1276

 Score = 26.9 bits (58), Expect = 6.8
 Identities = 12/37 (32%), Positives = 23/37 (62%), Gaps = 3/37 (8%)

Query: 70  TPFETPDQGKARLLTHWEQLDYGVQF---TSSRKFFT 103
           +P  TP +G  R+ TH +++D G ++   +S++  FT
Sbjct: 854 SPAGTPTEGLGRVSTHSQEMDSGTEYGMGSSTKASFT 890


>gi|239735588 TRAF2 and NCK interacting kinase isoform 6 [Homo
           sapiens]
          Length = 1297

 Score = 26.9 bits (58), Expect = 6.8
 Identities = 12/37 (32%), Positives = 23/37 (62%), Gaps = 3/37 (8%)

Query: 70  TPFETPDQGKARLLTHWEQLDYGVQF---TSSRKFFT 103
           +P  TP +G  R+ TH +++D G ++   +S++  FT
Sbjct: 875 SPAGTPTEGLGRVSTHSQEMDSGTEYGMGSSTKASFT 911


>gi|239735586 TRAF2 and NCK interacting kinase isoform 5 [Homo
           sapiens]
          Length = 1305

 Score = 26.9 bits (58), Expect = 6.8
 Identities = 12/37 (32%), Positives = 23/37 (62%), Gaps = 3/37 (8%)

Query: 70  TPFETPDQGKARLLTHWEQLDYGVQF---TSSRKFFT 103
           +P  TP +G  R+ TH +++D G ++   +S++  FT
Sbjct: 883 SPAGTPTEGLGRVSTHSQEMDSGTEYGMGSSTKASFT 919


>gi|239735584 TRAF2 and NCK interacting kinase isoform 4 [Homo
           sapiens]
          Length = 1323

 Score = 26.9 bits (58), Expect = 6.8
 Identities = 12/37 (32%), Positives = 23/37 (62%), Gaps = 3/37 (8%)

Query: 70  TPFETPDQGKARLLTHWEQLDYGVQF---TSSRKFFT 103
           +P  TP +G  R+ TH +++D G ++   +S++  FT
Sbjct: 901 SPAGTPTEGLGRVSTHSQEMDSGTEYGMGSSTKASFT 937


>gi|239735582 TRAF2 and NCK interacting kinase isoform 3 [Homo
           sapiens]
          Length = 1331

 Score = 26.9 bits (58), Expect = 6.8
 Identities = 12/37 (32%), Positives = 23/37 (62%), Gaps = 3/37 (8%)

Query: 70  TPFETPDQGKARLLTHWEQLDYGVQF---TSSRKFFT 103
           +P  TP +G  R+ TH +++D G ++   +S++  FT
Sbjct: 909 SPAGTPTEGLGRVSTHSQEMDSGTEYGMGSSTKASFT 945


>gi|239735580 TRAF2 and NCK interacting kinase isoform 2 [Homo
           sapiens]
          Length = 1352

 Score = 26.9 bits (58), Expect = 6.8
 Identities = 12/37 (32%), Positives = 23/37 (62%), Gaps = 3/37 (8%)

Query: 70  TPFETPDQGKARLLTHWEQLDYGVQF---TSSRKFFT 103
           +P  TP +G  R+ TH +++D G ++   +S++  FT
Sbjct: 930 SPAGTPTEGLGRVSTHSQEMDSGTEYGMGSSTKASFT 966


>gi|55741807 TRAF2 and NCK interacting kinase isoform 1 [Homo
           sapiens]
          Length = 1360

 Score = 26.9 bits (58), Expect = 6.8
 Identities = 12/37 (32%), Positives = 23/37 (62%), Gaps = 3/37 (8%)

Query: 70  TPFETPDQGKARLLTHWEQLDYGVQF---TSSRKFFT 103
           +P  TP +G  R+ TH +++D G ++   +S++  FT
Sbjct: 938 SPAGTPTEGLGRVSTHSQEMDSGTEYGMGSSTKASFT 974


>gi|21264602 laminin alpha 5 [Homo sapiens]
          Length = 3695

 Score = 26.9 bits (58), Expect = 6.8
 Identities = 12/26 (46%), Positives = 14/26 (53%)

Query: 5    VAHSEVNPNTRVMNSRGMWLTYALGV 30
            V HSE+    RV   R +WL Y L V
Sbjct: 1354 VTHSELTVTVRVPKGRWLWLDYVLVV 1379


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.327    0.141    0.443 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 5,559,697
Number of Sequences: 37866
Number of extensions: 225055
Number of successful extensions: 480
Number of sequences better than 10.0: 19
Number of HSP's better than 10.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 13
Number of HSP's that attempted gapping in prelim test: 474
Number of HSP's gapped (non-prelim): 19
length of query: 153
length of database: 18,247,518
effective HSP length: 93
effective length of query: 60
effective length of database: 14,725,980
effective search space: 883558800
effective search space used: 883558800
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 57 (26.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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